|
|
|
Welcome to the Quality Counts. For those health conscious consumers and medical professionals that are looking to purchase nutritional supplements, vitamins, herbs, learning about medications, losing weight, health food, low carbs, high protein nutrition, and exercise, you have come to the right place. Quality Counts serves both the medical practitioner and consumer interested in nutritional therapy and alternative medicine.
Home > Health Conditions > Memory Loss
Memory Loss
Related Topics:
Popular Supplements:
Alternative News:
-
Age-Associated
Mental Impairment - Life Extension Magazine
- Memory and Focus -
natmedonline.com
- Memory Loss - Dr.
Weil
-
Study supports Pycnogenol for better memory in elderly - Nutra USA, 3/18/08
- "150mg of Pycnogenol ... three months, the
participants receiving Pycnogenol had "significantly improved" memory, as seen
in a factor that combined accuracy scored from spatial working memory and
numeric working memory tasks" - See
Pine Bark/Pycnogenol products at iHerb
.
-
DHEAS
Levels Linked to Cognitive Function in Women - Medscape, 3/13/07 -
"There are data that suggest that DHEA and DHEAS may
have neuroprotective effects and that the decline in the production of these
steroids with healthy aging may contribute to neuronal dysfunction and
degeneration, and thus cognitive decline ... women with higher circulating
levels of DHEAS performed better on executive function tests. A positive
association was also observed between circulating DHEAS and higher scores on
tests of simple concentration and working memory in women with more than 12
years of education" - See
DHEA products at iHerb
.
-
Gingko may boost memory - if you remember to take it - Nutra USA, 2/28/08 -
"The new study involved 118 people age 85 and older with
no memory problems. The elderly subjects were randomly assigned to receive
either a ginkgo biloba extract (240 mg daily, provided by Thorne Research) or
placebo for three years. The extracts were independently verified to contain at
least six per cent terpene lactones and 24 per cent flavone glycosides ... when
the researchers considered only people who followed the directions in taking the
study pills, they found that people took at least 84 per cent of the supplements
as directed had a 68 per cent lower risk of developing mild memory problems"
- See
Ginkgo Biloba products at iHerb
.
-
A
randomized placebo-controlled trial of ginkgo biloba for the prevention of
cognitive decline - Neurology. 2008 Feb 27 - "In the
secondary analysis, where we controlled the medication adherence level, the GBE
group had a lower risk of progression from CDR = 0 to CDR = 0.5 (HR = 0.33, p =
0.02), and a smaller decline in memory scores" - See
Ginkgo Biloba products at iHerb
.
-
Folate
Deficiency Associated With Tripling Of Dementia Risk, Study Shows - Science
Daily, 2/5/08 - "Folate deficiency is associated with a
tripling in the risk of developing dementia among elderly people" - See
iHerb
folic acid products.
-
n-3
Fatty acids, hypertension and risk of cognitive decline among older adults in
the Atherosclerosis Risk in Communities (ARIC) study - Public Health Nutr.
2008 Jan;11(1):17-29 - "Word Fluency Test (WFT) ... an
increase of one standard deviation in dietary long-chain n-3 fatty acids (% of
energy intake) and balancing long-chain n-3/n-6 decreased the risk of 6-year
cognitive decline in verbal fluency with an odds ratio (95% confidence interval)
of 0.79 (0.66-0.95) and 0.81 (0.68-0.96), respectively, among hypertensives. An
interaction with hypertensive status was found for dietary long-chain n-3 fatty
acids (g day-1) and WFT decline (likelihood ratio test, P = 0.06). This exposure
in plasma cholesteryl esters was also protective against WFT decline,
particularly among hypertensives (OR = 0.51" - See Mega Twin EPA at
iHerb
.
-
Moderate Exercise May Cut Dementia Risk - WebMD,12/19/07-
"Moderate physical activity (such as walking and
climbing stairs) may help prevent dementia in people aged 65 and older"
-
Dietary intake adequacy and cognitive function in free-living active elderly: A
cross-sectional and short-term prospective study - Clin Nutr. 2007 Dec 12 -
"mini-mental state examination (MMSE) ... subjects whose
consumption of calcium was above the dietary reference intake had a
significantly higher odds ratio (OR) of improving their MMSE (OR=5.41; 95% CI:
1.44-20.29)" - See
calcium products at iHerb
.
-
DHEA sulfate levels are associated with more favorable cognitive function in
women - J Clin Endocrinol Metab. 2007 Dec 11 -
"In the multiple linear regression analysis the DHEAS term made a
significant independent positive contribution to the Controlled Oral Word
Association Test score, a measure of executive function. In addition, women
with a DHEAS level in the highest tertile who also had more than 12 years of
education performed better on both Digit Span Forward and Digit Span
Backward tests which are tests of simple concentration and working memory
respectively" - See
DHEA products at iHerb
.
-
Increased B12 levels could ward off dementia - Nutra USA, 11/16/07 -
"The longitudinal cohort study followed 1648
participants for 10 years, and found a doubling in holotranscobalamin (holoTC)
concentrations was associated with a 30 per cent slower rate of cognitive
decline ... increased levels of the amino acid homocysteine doubled the risk
of dementia or cognitive impairment" - [Abstract]
- See
iHerb
vitamin B12 products.
-
Fish for brain health supported by trio of studies - Nutra USA, 11/14/07
- "These recent reports are novel in that they
address the association of n-3 fatty acid intake and cognitive function in
non-demented individuals and, thus, present a shift in the attention to
earlier stages of cognitive decline with the hope of preventing progression
to states of dementia and disability before they become irreversible"
- See Mega Twin EPA at
iHerb
.
-
Eating Fish, Omega-3 Oils, Fruits And Veggies Lowers Risk Of Memory Problems
- Science Daily, 11/13/07 - "people who regularly
consumed omega-3 rich oils, such as canola oil, flaxseed oil and walnut oil,
reduced their risk of dementia by 60 percent compared to people who did not
regularly consume such oils. People who ate fruits and vegetables daily also
reduced their risk of dementia by 30 percent compared to those who didn't
regularly eat fruits and vegetables ... people who ate fish at least once a
week had a 35-percent lower risk of Alzheimer's disease and 40-percent lower
risk of dementia, but only if they did not carry the gene that increases the
risk of Alzheimer's, called apolipoprotein E4, or ApoE4 ... Given that most
people do not carry the ApoE4 gene, these results could have considerable
implications in terms of public health" - See Mega Twin EPA at
iHerb
.
-
The role of folate in depression and dementia - J Clin Psychiatry. 2007;68
Suppl 10:28-33 - "folate deficiencies may be caused by
improper absorption and utilization, often due to genetic polymorphisms.
Individuals, therefore, can have insufficient levels or lack needed forms of
folate, despite adequate intake. Supplementation with the active form of folate,
methyltetrahydrofolate, which is more readily absorbed, may be effective in the
prevention and treatment of both depression and dementia" -
See
iHerb
folic acid products.
-
Low vitamin B-12 status and risk of cognitive decline in older adults -
Am J Clin Nutr. 2007 Nov;86(5):1384-91 - "Low
vitamin B-12 status was associated with more rapid cognitive decline"
- See
iHerb
vitamin B12 products.
-
Cognitive performance among the elderly and dietary fish intake: the
Hordaland Health Study - Am J Clin Nutr. 2007 Nov;86(5):1470-8 -
"In the elderly, a diet high in fish and fish
products is associated with better cognitive performance in a dose-dependent
manner" - See Mega Twin EPA at
iHerb
.
-
n 3 Fatty acid proportions in plasma and cognitive performance in older
adults - Am J Clin Nutr. 2007 Nov;86(5):1479-85 -
"In this population, plasma n-3 PUFA proportions
were associated with less decline in the speed-related cognitive domains
over 3 y" - See Mega Twin EPA at
iHerb
.
-
Diet
Linked To Cognitive Decline And Dementia - WebMD, 11/6/07 -
"An article published in Annals of the New York
Academy of Sciences highlights information on the benefits of diets high in
fruit, vegetables, cereals and fish and low in saturated fats in reducing
dementia risk"
-
Diet
Of Walnuts, Blueberries Improve Cognition; May Help Maintain Brain Function
- Science Daily, 11/6/07 - "Diets containing two
percent, six percent, or nine percent walnuts, when given to old rats, were
found to reverse several parameters of brain aging, as well as age-related
motor and cognitive deficits"
-
The role of folate in depression and dementia - J Clin Psychiatry.
2007;68 Suppl 10:28-33 - "folate deficiencies may be
caused by improper absorption and utilization, often due to genetic
polymorphisms. Individuals, therefore, can have insufficient levels or lack
needed forms of folate, despite adequate intake. Supplementation with the
active form of folate, methyltetrahydrofolate, which is more readily
absorbed, may be effective in the prevention and treatment of both
depression and dementia" -
iHerb
folic acid products.
-
n-3 Fatty acids, hypertension and risk of cognitive decline among older
adults in the Atherosclerosis Risk in Communities (ARIC) study - Public
Health Nutr. 2007 Jul 12;:1-13 - "Word Fluency Test
(WFT) ... Findings indicated that an increase of one standard deviation in
dietary long-chain n-3 fatty acids (% of energy intake) and balancing
long-chain n-3/n-6 decreased the risk of 6-year cognitive decline in verbal
fluency with an odds ratio (95% confidence interval) of 0.79 (0.66-0.95) and
0.81 (0.68-0.96), respectively, among hypertensives. An interaction with
hypertensive status was found for dietary long-chain n-3 fatty acids (g
day-1) and WFT decline (likelihood ratio test, P = 0.06). This exposure in
plasma cholesteryl esters was also protective against WFT decline,
particularly among hypertensives (OR = 0.51"
-
Plasma folate concentration and cognitive performance: Rotterdam Scan Study
- Am J Clin Nutr. 2007 Sep;86(3):728-34 - "After
multivariate adjustment, the mean change in test score per 1-SD increase in
plasma folate was 0.05 (95% CI: 0.01, 0.09) for global cognitive function,
0.08 (95% CI: 0.04, 0.13) for psychomotor speed, and 0.02 (95% CI: -0.04,
0.07) for memory function ... The odds ratio relating a 1-SD increase in
plasma folate to the presence compared with the absence of severe white
matter lesions was 0.79 (95% CI: 0.66, 0.94), whereas no relation was seen
between folate status and hippocampal or amygdalar volume" - See
iHerb
folic acid products.
-
Caffeine May Help Women's Memory - WebMD, 8/6/07 -
"Women who reported drinking at least three cups of
coffee or tea per day at the study's start showed less of a drop in their
test scores during the study, compared with women who reported consuming at
most one daily cup of tea or coffee ... The biggest benefit was seen in the
women's verbal memory"
-
Tea, Chocolate Chemical May Boost Memory - WebMD, 5/30/07 -
"studied epicatechin, which is a
type of antioxidant called a flavonol, in female mice ... The mice that
consumed epicatechin did better at memorizing the maze than the mice that
got no epicatechin. The mice that consumed epicatechin and also ran on their
running wheels had the best results of all"
-
Moderate Alcohol Use May Slow Progression to Dementia - Medscape,
5/21/07 - "Moderate drinkers with
MCI who consumed 1 or fewer drink per day of wine had a significantly lower
rate of progression to dementia than did abstainers (HR, 0.15"
-
Fish consumption, n-3 fatty acids, and subsequent 5-y cognitive decline in
elderly men: the Zutphen Elderly Study - Am J Clin Nutr. 2007
Apr;85(4):1142-7 - "Fish consumers
had significantly (P = 0.01) less 5-y subsequent cognitive decline than did nonconsumers. A linear trend was observed for the relation between the
intake of EPA+DHA and cognitive decline (P = 0.01). An average difference of
approximately 380 mg/d in EPA+DHA intake was associated with a 1.1-point
difference in cognitive decline" - See Mega Twin EPA at
iHerb
.
-
Plasma n-3 fatty acids and the risk of cognitive decline in older adults:
the Atherosclerosis Risk in Communities Study - Am J Clin Nutr. 2007
Apr;85(4):1103-11 - "Promoting
higher intakes of n-3 HUFAs in the diet of hypertensive and dyslipidemic
persons may have substantial benefits in reducing their risk of cognitive
decline in the area of verbal fluency"
-
Folate And B12 May Influence Cognition In Seniors - Science Daily,
2/12/07 - "People with normal
vitamin B12 status performed better if their serum folate was high ... But
for people with low vitamin B12 status, high serum folate was associated
with poor performance on the cognitive test ... For seniors, low vitamin B12
status and high serum folate was the worst combination" - See
iHerb folic acid products
and
iHerb vitamin B12 products .
-
Report: Nutritional Strategies To Preserve Memory And Cognition - Life
Extension Magazine, 2/07
-
Folic acid effects two-faced depending on B12 levels, says study - Nutra
USA, 1/31/07 - "In this study of
older Americans in the age of folic acid fortification, we found direct
associations between high serum folate and both anaemia and cognitive
impairment in subjects with low vitamin B12 status ... Among subjects with
normal vitamin B12 status, on the other hand, high serum folate was
associated with protection from cognitive impairment" - See
iHerb
vitamin B12 products.
-
Effect of 3-year folic acid supplementation on cognitive
function in older adults in the FACIT trial: a randomised, double blind,
controlled trial - Lancet. 2007 Jan
20;369(9557):208-16 - "Folic acid
supplementation for 3 years significantly improved domains of cognitive
function that tend to decline with age"
-
Folic Acid Improves Cognitive Performance in Older Adults - Medscape,
1/19/07 - "Patients were randomized
to either placebo or 800 µg daily of folic acid for 3 years ... 3 years of
treatment with folic acid conferred on individuals resulted in the
performance of someone 4.7 years younger for memory, 1.7 years younger for sensorimotor speed, 2.1 years younger for information processing speed, and
1.5 years younger for global cognitive function"
- See
iHerb
folic acid products.
-
Can
Fish Intake Predict Chances Of Developing Dementia? - Science Daily,
1/3/07 - "the participants who
reported consuming an average of about three servings of oily fish a
week--equivalent to blood levels of DHA at 180 milligrams daily--were
associated with a significantly reduced risk of developing dementia of all
types, including Alzheimer's disease. No other fatty acid blood level was
independently linked to the risk of dementia" - See
Jarrow Max DHA at iHerb
.
-
Higher Level Of Certain Fatty Acid Associated With Lower Dementia Risk -
Science Daily, 11/28/06 - "men and
women in the quartile with the highest DHA levels had a 47 percent lower
risk of developing dementia and 39 percent lower risk of developing
Alzheimer's disease than the other three quartiles with lower DHA levels ...
those in the top quartile of blood DHA levels reported that they ate an
average of .18 grams of DHA a day and an average of three fish servings a
week. Participants in the other quartiles ate substantially less fish"
- See
iHerb
or
Vitacost
DHA products. My favorite is
Jarrow Max DHA at iHerb .
-
Vegetables May
Help Save Brain's Vigor - WebMD, 10/23/06 -
"All participants had some mental
slowdown as they aged ... But the yearly slowdown was 40% slower for people
who ate the most vegetables -- three or four servings daily -- compared with
those who ate less than one serving daily"
-
Natural Chemical Found In Strawberries Boosts Memory In Healthy Mice -
Science Daily, 10/20/06 - "Fisetin,
a naturally occurring flavonoid commonly found in strawberries and other
fruits and vegetables, stimulates signaling pathways that enhance long-term
memory"
-
Berries May Help Keep Brain Sharp - WebMD, 8/24/06 -
"The radiated rats that had eaten the
plain chow performed worst on the maze tests and had the lowest dopamine levels
of any of the rats ... But the berry-eating, radiated rats didn't show those
shortfalls. Their test results were generally comparable to those of rats that
hadn't been radiated"
-
Apple Juice May
Boost Memory - WebMD, 8/4/06 -
"consumption of antioxidant-rich foods such as apples and apple juice can
help reduce problems associated with memory loss"
-
Preventive Maintenance For the Brain - WashingtonPost.com, 2/21/06 -
"increased mental activity
throughout life appears to preserve brainpower ... those who exercised the
most -- at least three times a week -- were least likely to develop
Alzheimer's disease ... diet (for brain health, nutritionists suggest a diet
low in saturated fats and rich in vegetables, fruit and fish with omega-3
fatty acids), social life (an active one is thought to improve immunity and
reduce inflammation, believed to play a role in Alzheimer's) and health
problems like diabetes and heart disease"
-
Green Tea May Do
Wonders for the Brain - WebMD, 2/17/06 -
"Those who reported drinking the
most green tea were least likely to show cognitive impairment, based on
their test scores ... Drinking at least two daily cups of green tea was tied
to the lowest risk of cognitive impairment" - See
iHerb
or
Vitacost
green tea products.
- Staying
active helps keep the mind sharp - MSNBC, 1/16/06 -
"healthy people who reported
exercising regularly had a 30 to 40 percent lower risk of dementia"
- Folic Acid
to Boost Memory? - Dr. Weil, 12/13/05 -
"those who took the folic acid had
memory scores equal to people five and a half years younger"
-
Low Vitamin E Serum Levels Correlate With Dementia Risk - Clinical
Psychiatry News, 10/05 - "those
individuals in the bottom tertile of vitamin E plasma levels were at
significantly higher risk not only of being demented (OR 2.6, 95% CI) but
also of having impaired cognitive function (OR 2.2, 95% CI), compared with
the highest vitamin E tertile"
-
Eating Fish Associated with Slower Cognitive Decline - Doctor's Guide,
10/12/05 - "Consuming fish at least
once a week was associated with a 10% per year slower rate of cognitive
decline in elderly people ... consumption of one omega-3 fatty acid in
particular, docosahexaenoic acid (DHA), is important for memory performance
in aged animals" - See
iHerb
or
Vitacost
DHA products. My favorite is
Jarrow Max DHA at iHerb .
-
Fish Fights Aging in the Brain - WebMD, 10/10/05 -
"eating fish at least once a week
slowed the rate of mental or cognitive decline in elderly people by 10%-13%
per year ... Researchers attribute the protective effects of fish on the
brain to omega-3 fatty acids" - See Mega Twin EPA at
iHerb
or
Vitacost .
-
Obesity at Midlife Raises Dementia Risk Later - WebMD, 10/10/05 -
"people who were obese at midlife
were nearly 2.5 times more likely to develop dementia more than 20 years
later than those who were normal weight ... high blood pressure and total
cholesterol levels at midlife also doubled the risk of dementia in later
life ... when a person had all three of these risk factors at midlife, the
risk of dementia or Alzheimer's disease was six times higher"
-
Fish Consumption and Cognitive Decline With Age in a Large Community Study
- Arch Neurol. 2005;62 - "Compared
with a decline rate in score of –0.100 SU/y among persons who consumed fish
less than weekly, the rate was 10% slower (–0.090 SU/y) among persons who
consumed 1 fish meal per week and 13% slower (–0.088 SU/y) among persons who
consumed 2 or more fish meals per week"
-
Preserving and Restoring Brain Function
- Life Extension Magazine, 10/05 -
"Clinical trials using small groups of patients with cognitive decline
demonstrated significant improvements with phosphatidylserine
supplementation, especially among patients in the early stages"
-
Veggies May Keep an Aging Brain Sharp - WebMD, 9/28/05
-
Leafy Green Vegetables May Help Keep Brains Sharp Through Aging -
Science Daily, 9/26/05 - "men who
obtained more folate in their diets showed significantly less of a decline
in verbal fluency skills over the course of three years than did men with
lower dietary folate intake ... High folate levels, both in the diet and in
the blood, also appeared to be protective against declines in another
category of cognitive skills known as spatial copying"
-
Exercise could build brain cells in elderly, study suggests - USAToday,
9/20/05 - "Older mice that exercised
on a running wheel developed new brain cells and learned a new task more
effectively than older mice that took it easy all day"
-
Midlife Obesity Linked to Late-Life Dementia - WebMD, 4/28/05 -
"For those with an obese BMI (30 or
higher) in middle age, the risk of dementia in old age was 74% higher than
for those with normal BMI. For those who were overweight (BMI of 25-29.9),
late-life dementia risk was 35% higher than those with normal BMI"
-
Fruit and vegetable consumption and cognitive decline in
aging women - Ann Neurol 2005;57:713-720 - "Fruits were not
associated with cognition or cognitive decline. However, total vegetable
intake was significantly associated with less decline. Specifically, on a
global score combining all tests, women in the highest quintile of
cruciferous vegetables declined slower (by 0.04 unit; 95% confidence
interval, 0.003, 0.07; p trend = 0.1) compared with the lowest quintile.
Women consuming the most green leafy vegetables also experienced slower
decline than women consuming the least amount (by 0.05 unit; 95% confidence
interval, 0.02, 0.09; p trend < 0.001). These mean differences were
equivalent to those observed for women about 1 to 2 years apart in age"
-
Preventing Age-Related Cognitive Decline
- Life Extension Magazine, 4/05 -
"Free radicals are a significant culprit, interfering with energy
metabolism, blood flow, and nerve structure and function. Mitochondrial
energy boosters, vitamins, hormones, and other antioxidants are effective
weapons in the war against oxidative stress, safely enhancing energy
production and blood flow, suppressing inflammation, maintaining the
structural integrity of nerve cell components, and facilitating neuronal
activity"
-
Low Fatty Acid Levels, Dementia Associated in Large Study - Clinical
Psychiatry News, 3/05 - "The n-3
fatty acids are an important component of the neuronal membrane, influencing
membrane fluidity and all the related functions, such as signal transduction
and enzyme function ... Subjects with dementia had the lowest n-3 fatty acid
plasma concentrations ... Subjects with dementia had the highest plasma
concentrations of saturated fatty acids" - See Mega Twin EPA at
iHerb
or
Vitacost .
-
Cardiovascular Exercise Improves the Aging Brain - Clinical Psychiatry News, 2/05 -
"Cardiovascular exercise improves cognitive performance and cortical function in elderly people, and it also appears to roll back age-related losses in brain volume"
- Neuropsychology of vitamin B12 deficiency in elderly dementia patients and control subjects - J Geriatr Psychiatry Neurol. 2005 Mar;18(1):33-38 -
"cobalamin deficiency may cause a reversible dementia in elderly patients"
- Physical Activity in Old Age Keeps Mind Sharp - WebMD, 12/28/04 -
"elderly men who decreased the duration or intensity of their physical activity level
over a 10-year period experienced a greater decline in cognitive skills, such as attention, memory, and language skills, than men who maintained the intensity of their physical activity"
- MIT: Magnesium May Reverse Middle-age Memory Loss - Science Daily, 12/27/04 -
"In the cover story of the Dec. 2 issue of Neuron, MIT researchers report a
possible new role for magnesium: helping maintain memory function in middle age and beyond ... magnesium helps regulate a key brain receptor important for learning and memory" - See
iHerb
or
Vitacost
magnesium products.
- Memory Loss - Medscape, 12/7/04 -
"diets high in saturated fats and trans-unsaturated fats are associated with greater declines in cognitive functioning.[21] The antioxidants
vitamins E and C are thought to reduce risk of Alzheimer's disease (AD),[22] and folate, vitamins B12 and B6 have been shown to play a role in cognitive functioning in women.[23-25] Two recent reviews support the positive influences of a "heart-healthy" diet on reducing risk of cognitive decline[26] and AD.[27]
Foods high in vitamin E, omega-3 fatty acids, unsaturated fat, and nonhydrogenated fat are the most likely to reduce risk of cognitive decline"
-
Patients who follow standard preventive health advice may protect themselves against dementia - Clinical Psychiatry News, 12/04 -
"Eat more veggies ... Eat less saturated fat ... Turn off the TV ... Keep your brain, body, and social life active"
-
Nourishing Your Noggin - WebMD, 9/22/04 -
"For a long time, people believed
that a common component of vitamin E called alpha tocopherol was most
important, but another form called gamma tocopherol is definitely a
protective antioxidant in brain disorders"
- Walk Away From Dementia - WebMD, 9/21/04 -
"Those who walked more than 2 miles a day were nearly half as likely to get dementia as men who walked less
than one-quarter mile a day"
- Berries Good For Your Memory - Intelihealth, 7/16/04 -
"rats that had blueberry matter added to their diet at age 15 months -- middle
age in the rat world, and the time memory problems begin -- did much better on memory tests at 19 months (old age in rats) than same-age rats eating the same diet without blueberries"
- Homocysteine, folate, and vitamin B-12 in mild cognitive impairment, Alzheimer disease, and vascular dementia - Am J Clin Nutr. 2004 Jul;80(1):114-22 -
"Subjects in the lowest folate tertile had significantly higher adjusted odds ratios (ORs)
for mild cognitive impairment ... Hyperhomocysteinemia was significantly associated with dementia" - See
iHerb
or Vitacost folic acid products.
- Memory enhancer named best new ingredient - Functional Foods and Nutraceuticals, 4/04 -
"Citicoline is a form of choline that helps replenish the brain with
phosphatidylserine ... In a double-blind trial of 84 elderly patients with mild to moderate memory loss, subjects who took 1000mg of citicoline daily for six weeks showed improvement in the acquisition of new information and its recall and improvement in global memory efficiency" - See
iHerb
or
Vitacost
citicoline products.
- Diet May Improve Cognition, Slow Aging, And Help Protect Against Cosmic Radiation - Intelihealth, 11/10/03 -
"The role of diet in cognitive function is one
of the vastly understudied areas in the neurosciences ... old dogs that were on an antioxidant diet performed better on a variety of cognitive tests than dogs that were not on the diet ... aged rats on the blueberry-enriched diet had lower NF-kappaB
levels than aged rats fed a control data ... among the aged rats, the higher the NF-kappaB levels, the poorer their memory scores"
- Soy Isoflavones May Improve Cognition in Postmenopausal Women - Healthwell Exchange Daily News, 10/2/03 -
"Women taking soy
isoflavones had significant improvements in recall, logical thinking, planning tasks, and attention compared with women taking a placebo, which translates to better memory and ability to focus on a particular task"
- Creatine May Boost Brain Performance - WebMD, 8/13/03 -
"Forty-five vegetarian young adults received either 5 grams of creatine or a placebo
powder for six weeks, followed by six weeks of no supplementation. The groups were then switched, and the placebo group received creatine for six weeks and vice versa ... The researchers found that creatine supplementation gave a "significant, measurable boost to brain power." In a memory test that asked
participants to recall a string of numbers, people taking creatine recalled an average of 8.5 numbers vs. seven for people not taking the supplement" - See
iHerb
or
Vitacost
creatine products.
- E and C May Give Older Women a Mental Edge - Natural Foods Merchandiser, 8/03 -
"The women who had taken vitamin C
and E supplements for more than 10 years scored an average of 1.5 years younger in cognitive function than those not taking vitamins. The results were even more marked for those with low dietary vitamin E intake: Women with the lowest 30 percent of dietary vitamin E intake who did not
take supplements tested two years older in mental function than women who compensated for low dietary intake with antioxidant supplements"
- Music Lessons Boost Verbal Memory - WebMD, 7/28/03
- Chinese Herb [Gastrodine (also called gastrodin)/Gastrodia elata] May Treat Vascular Dementia - WebMD, 6/11/03 -
"Patients who took gastrodine three times a day
for 12 weeks did better on tests of mental function and behavior than patients who took Duxil"
- Antioxidants May Protect Against Alcohol Damage - Intelihealth, 6/3/03 -
"fed rats a liquid diet containing alcohol for six weeks ... They found a 66
percent decrease in the number of new cells in crucial parts of the brain and an increase in cell death of more than 227 percent ... But in rats that also received injections of the antioxidant
ebselen, the damage to developing cells did not occur ... The antioxidant ebselen
was used because it is known to have protective effects in the liver and digestive tract and has few side effects in humans"
- Cognitive decline and fatty acid composition of erythrocyte membranes - Am. J. of Clinical Nutr., 4/03 -
"studied the relation between
erythrocyte membrane fatty acid composition and cognitive decline in free-living volunteers ... Higher proportions of both stearic acid (saturated, 18:0) and total
n-6 polyunsaturated fatty acids were associated with greater risk of cognitive decline ... Conversely, a higher proportion of total n-3 fatty acids was associated with a lower risk of cognitive decline"
- Effects of Obesity Reach Into Brain - WebMD, 3/5/03 -
"obesity works independently -- as well as in conjunction with other
risk factors -- to cause a decline in thinking ability, especially memory and learning ... participants may have suffered from heart disease risk factors that were undetectable 50 years ago ... other social and psychological factors associated with obesity and overeating, such as depression and anxiety, may have
also affected the decline ... may damage brain function by making it harder for blood to reach the brain, similar to high blood pressure and heart disease"
- Alzheimer's Disease and Dementia: Vitamins Can Help Prevent - WebMD, 2/28/03 -
"High levels of a substance in the blood called
homocysteine tops the list of potentially new risk factors for heart disease, stroke, and now dementia. A new study suggests that high homocysteine levels are linked with mental
declines associated with Alzheimer's disease in elderly people ... High homocysteine levels can be treated very easily with vitamins, including folate, niacin, and B-12"
-
HDL Cholesterol Level Linked To Longevity, Cognitive Function - Clinical Psychiatry News, 2/03 -
"A
group of centenarians maintained significantly higher than normal HDL cholesterol levels, and within the group the parameter was strongly correlated with cognitive function ... The centenarians' offspring were also significantly healthier than their spouses:
They were half as likely to have diabetes or heart attacks and had significantly lower blood pressure. No strokes occurred among the offspring ... The presence of HDL might explain the health and longevity in these families. The serum concentration of HDL typically declines with age by a mean of 5 mg/dL
every 8 years ... Had the decline followed the normal pattern, the centenarians' HDL would have been about 20 mg/dL. But the actual mean value in the group was 55 mg/dL"
- See my HDL page for ways to raise it.
- Exercise Saves Brain Cells - WebMD, 1/29/03 -
"aerobic exercise can help protect brain tissue from age-related damage and mental decline ... the brain
loses an average of 15% to 25% of its tissue between the ages of 30 and 90 ... exercise decreased the amount of brain-tissue loss associated with aging"
- Using Complementary Treatments - PsychiatricTimes.com, 11/15/02 -
"Ginseng is known as an adaptogen.
Animal studies report a reversal of scopolamine-induced memory deficits in rats, an increase in acetylcholine uptake and improved learning performance. In humans, two randomized, controlled trials reported some improvement in cognitive function over eight and 12 weeks of ginseng use. Another study, looking
specifically at 50 elderly subjects, reported improvement over baseline measures ... Research has shown huperzine A to be a selective and reversible inhibitor of acetylcholinesterase.
It also has been shown to lessen neuronal toxicity caused by glutamate. Initial small investigations reported improvement in cognitive functions of subjects with AD ... Phosphatidylserine is active at cell membranes, including synaptic membrane zones. Partial improvement of learning and
recall capacity was noted in subjects with age-related cognitive decline"
- Cognitive Training Improves Memory, Reasoning, Concentration In Seniors - Doctor's Guide, 11/13/02
- The Bias is Overwhelming
- Vitacost, 8/21/02 - "It is rather appalling that the news media has been giving so much attention to this ridiculously short term negative study on ginkgo. It is even more appalling that some media sources come up with catchy
phrases like “Forget the ginkgo”. Six weeks is not enough time for any supplement or drug to work when it comes to memory"
- An Indian Spice for Alzheimer’s? - Dr. Weil, 6/12/02 -
"Curcumin blocked the accumulation of beta-amaloid
plaque and also appeared to reduce inflammation related to Alzheimer’s disease in neurologic tissue. The rats fed curcumin also performed better on memory tests than
rats on normal diets ... Researchers at the University of Illinois have also found that it helps prevent plaque formation. And preliminary studies at Vanderbilt University suggest that curcumin may block the progression of multiple sclerosis ... only low dose curcumin reduced plaque in the
Alzheimer’s disease studies ... Turmeric appears to have significant anti-inflammatory and cancer-protective effects as well"
- Active Life Keeps Brain Healthy - WebMD, 5/21/02 -
"An active lifestyle -- even if begun only in middle age -- spurs brain-cell growth and lowers risk of
Alzheimer's disease ... In another study published in the same issue of the Annals of Neurology, researchers find that a particular chemical in the blood may be linked to Alzheimer's and other dementing diseases ... The chemical is called hs-CRP. It is a sign of
inflammation -- the body's protective response to injury or infection" - See my inflammation page for natural ways to reduce it.
- Nutrition Affects Thinking in Elderly - WebMD, 4/25/02 -
"In this study of healthy elderly people, higher concentrations of
folic acid and vitamin B-12 were associated with increased memory and thinking ability"
- Breakfast Gives Memory a Boost - HealthandAge, 1/11/02
- Caffeine Sharpens the Mind - WebMD, 12/20/01 -
"The researchers looked at 40 people over 65 and tested their memory in the morning and again in the
afternoon a few days later. Each time, they drank a 12 oz. cup of coffee before going through a series of memory tests. Some drank decaffeinated coffee and some had the real thing but were not told which one they were getting ... those who drank decaffeinated coffee "showed a significant decline in memory
performance from morning to afternoon," Ryan says. Those who drank the caffeine had no fall in their memory test scores"
-
Memory
vitamins - Life Extension Magazine, 9/01 - "Folate and vitamin B12 work together to enhance cognition"
-
It
is Never Too Late to Regenerate Your Brain - Life Extension Magazine, 6/01 -
"Lower your stress, lower your cortisol levels and it is likely that your brain can regenerate its powers to learn and remember"
-
Vitamin
B12: Surprising New Findings - Life Extension Magazine, 12/00
- Breakfast May Improve Memory in Healthy Elderly - Doctor's Guide, 10/24/01
- Alzheimer's Disease May Be Linked to Deficiencies in Vitamin B12 or Folate - Doctor's Guide, 5/8/01 -
"Study authors theorized that vitamin B12 or folate deficiencies affect Alzheimer's disease by
influencing neurotransmitters or the levels of the amino acid homocysteine in the body. Either vitamin B12 or folate deficiency can increase homocysteine levels. Homocysteine has a neurotoxic effect that could lead to cell death or neurological conditions such as Alzheimer's disease"
- Folic Acid May Reduce Age-Related Memory Problems - WebMD, 4/27/01 -
"High homocysteine levels were independently associated with poor performance on the memory tests, as were low levels of the
vitamin folic acid. Folic acid, or folate, has been shown to significantly lower homocysteine levels ... a cocktail of three vitamin supplements -- folic acid, B12, and B6 -- can dramatically lower homocysteine levels, even in those who get the recommended levels of the vitamins in their diets ... Homocysteine
levels naturally increase as you age ... Jacobsen, 62, recommends taking 400-800 mcg of folic acid every day and 25-100 mg of vitamin B6. He says it is not clear if B12 supplementation is beneficial in younger people, but it does appear to benefit those over 50. He takes 500 mcg of B12 each day"
- Exercise Shown to Help Keep Elderly Minds More Alert - WebMD, 4/10/01 -
"after taking into consideration factors such as age, sex, and level of education, people who engaged in all levels of
physical activity from low to high had lower risks for thinking impairment, and were also less likely to have Alzheimer's disease or other forms of dementia"
- Sustain the Brain - Nutrition Science News, 2/01
- A Drink A Day May Keep Memory OK - WebMD, 8/1/00
-
Enhancing
Cognitive Function - Life Extension Magazine, 5/00
- Cocktails & Vitamin E Improve Memory - Nutrition Science News, 11/99
- Brain boosters: Pills and potions - CNN, 11/5/99
- Smart foods - CNN, 6/24/99
Memory and Hypertension:
-
n-3
Fatty acids, hypertension and risk of cognitive decline among older adults in
the Atherosclerosis Risk in Communities (ARIC) study - Public Health Nutr.
2008 Jan;11(1):17-29 - "Word Fluency Test (WFT) ... an
increase of one standard deviation in dietary long-chain n-3 fatty acids (% of
energy intake) and balancing long-chain n-3/n-6 decreased the risk of 6-year
cognitive decline in verbal fluency with an odds ratio (95% confidence interval)
of 0.79 (0.66-0.95) and 0.81 (0.68-0.96), respectively, among hypertensives. An
interaction with hypertensive status was found for dietary long-chain n-3 fatty
acids (g day-1) and WFT decline (likelihood ratio test, P = 0.06). This exposure
in plasma cholesteryl esters was also protective against WFT decline,
particularly among hypertensives (OR = 0.51" - See Mega Twin EPA at
iHerb
.
-
High
Blood Pressure Associated With Risk For Mild Cognitive Impairment - Science
Daily, 12/12/07 - "Hypertension (high blood pressure)
was associated with an increased risk of all types of mild cognitive impairment
that was mostly driven by an increased risk of non-amnestic mild cognitive
impairment ... Preventing and treating hypertension may have an important impact
in lowering the risk of cognitive impairment"
-
High
Blood Pressure May Heighten Effects Of Alzheimer's Disease - Science Daily,
11/28/07 - "Having hypertension, or high blood pressure,
reduces blood flow in the brains of adults with Alzheimer's disease"
-
Arterial
Stiffness and Memory and Concentration - Medscape, 11/23/07 -
"Increasing pulse-pressure levels and higher baseline
pulse-wave velocity — indications of increased arterial stiffness — were linked
to a decline in memory and concentration among aging individuals who
participated in the Baltimore Longitudinal Study of Aging"
-
High
Blood Pressure Or Irregular Heartbeat Linked To Alzheimer's Disease Progression
- Science Daily, 11/5/07 - "10 with high blood pressure
(systolic pressure over 160) at the time of AD diagnosis showed a rate of memory
loss roughly 100 percent faster than those with normal blood pressure ... 10
with atrial fibrillation at the time of the diagnosis showed a rate of memory
decline that was 75 percent faster than those with normal heartbeats"
-
Antihypertensive Treatment May Help Maintain Memory - Medscape, 9/27/07 - "Pretreatment
correlation of parietal and prefrontal change was 0.61 vs 0.94 after treatment.
According to the investigators, similar differences were observed for all areas,
with an average pretreatment correlation of 0.66 vs an average posttreatment
correlation of 0.91"
-
Some
Hypertension Drugs May Help Reduce Dementia Risk - Science Daily, 5/5/07 -
"Centrally acting drugs include captropril (Capoten®), fosinopril (Monopril®), lisinopril (Prinivil® or Zestri®),
perindopril (Aceon®), ramipril (Altace®) and trandolapril (Mavik®) ... The study
found a link between taking centrally active ACE inhibitors and lower rates of
mental decline as measured by the Modified Mini-Mental State Exam, a test that
evaluates memory, language, abstract reasoning and other cognitive functions"
-
Elderly Blood Pressure Variability Affects Cognitive Function - Doctor's
Guide, 5/26/06 - "study suggested that
lowering the systolic BP by 20 mm Hg or diastolic blood pressure by 10 mm Hg
would have a considerable beneficial effect on the preservation of cognitive
abilities in the whole population"
-
Senior Moment? Check Blood Pressure - WebMD, 5/17/06 -
"the greater the numeric differences
in blood pressure readings during the day, the greater the risk of cognitive
dysfunction"
-
Sustained Blood Pressure Treatment Lowers Dementia Risk In Elderly -
Science Daily, 4/10/06 - "each year
of treatment reduced the risk of developing dementia during the follow-up
period by about 3 percent. Compared with men who were never treated for
hypertension, the risk of developing dementia during the follow-up period
was: ... 60 percent lower in those treated more than 12 years -- similar to
the risk in a control group of 446 men with normal blood pressure"
-
Uncontrolled High Blood Pressure Means More Cognitive Problems in Old Age
- Doctor's Guide, 12/5/05
-
Hypertension Control May Lower Risk of Dementia - Clinical Psychiatry
News, 10/13/05 - "effective
antihypertensive therapy may reduce cognitive decline in these patients"
-
Brain May Benefit by Lowering Blood Pressure - WebMD, 9/7/05 -
"lowering blood pressure may halt or
slow the progression of brain abnormalities called white matter hyperintensities (WMH) ... WMH may be accompanied by dementia, depression,
and trouble with walking"
-
High Blood Pressure Related Decline in Cognitive Function Affects Adults Young and Old - Doctor's Guide, 10/5/04 -
"To the
extent that BP (blood pressure) effects on cognition are not reversible, it is important to prevent an increase in BP levels as early as possible in the life cycle"
- Hypertension Linked to Cognitive Decline at All Ages - Medscape, 10/4/04
- High Blood Pressure and the Elderly Mind - WebMD, 10/30/03
- Hypertension May not Speed Brain Decline - WebMD, 9/29/03
- High Blood Pressure Causes Memory Lapse? - WebMD, 9/23/03 -
"some short-term memory lapses often attributed to aging may actually result from having
high blood pressure"
- Perindopril/Indapamide Therapy May Help Reduce Dementia Risk In Patients With Cerebrovascular Disease - Doctor's Guide, 6/16/03
- Low Blood Pressure and Risk of Dementia in the Kungsholmen Project: A 6-Year Follow-up Study - Archives of Neurology, 2/03 -
"Subjects with
very high systolic pressure (>180 vs 141-180 mm Hg) had an adjusted relative risk of 1.5 (95% confidence interval [CI], 1.0-2.3; P = .07) for Alzheimer disease,
and 1.6 (95% CI, 1.1-2.2) for dementia ... high diastolic pressure (>90 mm Hg) was not associated with dementia incidence, whereas extremely low diastolic pressure (65 vs 66-90 mm Hg) produced an
adjusted relative risk of 1.7 (95% CI, 1.1-2.4) for Alzheimer disease and 1.5 (95% CI, 1.0-2.1; P = .03) for dementia"
- Blood Pressure Linked To Cognitive Performance In Elderly Men - Doctor's Guide, 2/11/03 -
"Diastolic
blood pressure at 68 years of age showed an inverse relationship to men's performance on verbal, spatial and speed assessments when tested at 81 years ... systolic blood pressure at 68 years showed an inverse relationship with spatial performance"
-
BP Lowering May Halt Descent Into Dementia - Clinical Psychiatry News, 12/02 -
"Dr. Hansson served as cochair of SCOPE, a 15-nation study in which 4,937 mildly hypertensive patients aged
70-89 were randomized to the angiotensin-receptor blocker candesartan or diuretic-based therapy. Serial Mini-Mental Status Exams (MMSEs)
conducted during more than 18,000 patient-years of follow-up demonstrated that among individuals with a baseline MMSE of 24-28—indicative of normal to slightly impaired cognitive function—those in the candesartan arm had a
mean 0.5-point decline in MMSE scores during follow-up, compared with a 6-point drop in those on a diuretic. The cognitive benefit was even more pronounced in patients over age 85"
- Blood Pressure Medication Preserves Cognitive Function In Older African-Americans - Doctor's Guide, 10/14/02
- Blood Pressure Meds Help Heart and Mind - WebMD, 10/14/02
- Blood Pressure Drugs Keep Brain Healthy - KGTV.com, 10/14/02 -
"the continuous use of medications to lower
blood pressure reduced the risk of memory loss by more than one-third"
- Hypertension May Signal Vascular Dementia For Some In Later Life - Doctor's Guide, 5/7/02
- Lowering High Blood Pressure Can Reverse Some Dementia in the Elderly, Improves Memory and Thinking Limited by Vascular Dementia - WebMD, 5/18/01 -
"At 12 weeks, both thinking and memory improved by
15% to 40%, and there were similar improvements in gait and other movements, says Jacobson. These improvements were still present at six months"
- Blood Pressure Control Improves Cognitive Function In Hypertensive Patients - Doctor's Guide, 5/17/01 -
"When the tests were repeated at 12 and 24 weeks, patients averaged a 15-40 percent improvement in the
areas of executive function, memory, concentration and information processing, as well as spatial skills and some motor function"
- Short-term Cognition Improves With Seroquel (Quetiapine Fumarate) for Schizophrenia or Schizoaffective Disorder - Doctor's Guide, 5/8/01
- Cognitive Effects Seen With Mild Hypertension - Doctor's Guide, 2/19/01 -
"But even in these young, high functioning, mild hypertensives you can find differences and deficits in cognitive function of about 4
Intelligence Quotient (IQ) points."
- Dementia Protection Of Anti-Hypertensive Medication Underestimated - Doctor's Guide, 1/23/01
- Lower Blood Pressure Means Less Chance of Dementia, Study Finds Thinking Skills Fall in People With High BP - WebMD, 12/14/00
- High blood pressure, cholesterol and weight increase dementia risk - Doctor's Guide, 5/2/00
- High Blood Pressure Linked To Mental Decline - Doctor's Guide, 11/10/98
- Antihypertensive Drugs May Lower Risk Of Dementia - Doctor's Guide, 10/23/98
- High Blood Pressure Could Mean Greater Risk Of Dementia - Doctor's Guide, 3/19/98
- High Blood Pressure Speeds Brain Shrinkage And Memory Loss In Elderly - Doctor's Guide, 7/7/97
- Research: Hypertension speeds up brain aging, shrinkage - CNN, 7/7/00
General Information:
-
Memory loss - American Academy of Family Physicians
-
Memory loss - emedicine.com
-
Memory loss - FamilyDoctor.org
-
Aging And Your Mind - Intelihealth
Other News:
-
Perk of Good Job: Aging Mind Is Sharp - WebMD, 5/7/08 -
"Jobs that have elements where you need to solve
problems, plan and organize, and think flexibly and on your feet appear to
carry cognitive benefits throughout your life. You can potentially draw on
them later as reserves"
-
Memory Of One In Three People Over 70 Is Impaired, Study Shows - Science
Daily, 3/18/08 - "More than a third of people over
age 70 have some form of memory loss according to a national study by a team
of researchers at Duke University Medical Center"
-
Stress Hormone Impacts Memory, Learning In Diabetic Rodents - 2/17/08 -
"A new study in diabetic rodents finds that
increased levels of a stress hormone produced by the adrenal gland disrupt
the healthy functioning of the hippocampus, the region of the brain
responsible for learning and short-term memory. Moreover, when levels of the
adrenal glucocorticoid hormone corticosterone (also known as cortisol in
humans) are returned to normal, the hippocampus recovers its ability to
build new cells and regains the "plasticity" needed to compensate for injury
and disease and adjust to change"
-
More
Brain Research Suggests 'Use It Or Lose It' - Science Daily, 2/7/08 -
"It appears that if a cell is not appropriately
stimulated by other cells, it self-destructs ... This self-destruct process
is also known to be an important factor in stroke, Alzheimer's and motor
neuron diseases, leading to the loss of essential nerve cells from the adult
brain"
-
Testosterone May Improve Mental Function - Science Daily, 1/14/08 -
"higher testosterone levels in midlife have been
linked to better preservation of tissue in some parts of the brain. And in
older men, higher testosterone levels have been associated with better
performance on cognitive tests ... Three studies linked impaired performance
on cognitive tests with androgen deprivation therapy"
-
Stiff Arteries May Stifle Aging Mind - WebMD, 11/20/07 -
"A new study links stiffer arteries to lower memory
and concentration test scores as adults age"
-
Cholesterol Drugs May Reduce Dementia & Parkinson's Risk - Physician's
Weekly Article, 10/15/07 - "there appears to be a
strong reduction in dementia and Parkinson’s disease incidence attributed to
the use of simvastatin, a cholesterol lowering drug. The researchers also
observed a moderate reduction in incidence of these conditions with
atorvastatin, another cholesterol-lowering drug"
-
Higher serum free testosterone is associated with better cognitive function
in older men, while total testosterone is not. The Health In Men Study -
Clin Endocrinol (Oxf). 2007 Sep 20 - "In
community-dwelling older men, serum free testosterone >/= 210 pmol/l is
associated with better cognitive performance"
-
ACE Inhibitors May Protect Against Mental Decline - Clinical Psychiatry
News, 8/07 - "The group of patients on an
antihypertensive other than an ACE inhibitor had a mean decline in exam
scores of 0.64 points per year. Those on an ACE inhibitor had a mean decline
of 0.38 points per year ... It is thought that some ACE inhibitors protect
from dementia and mental decline by decreasing oxidative stress and
inflammation in the brain"
-
Sleep Strengthens Your Memory - Science Daily, 4/24/07
-
Strengthen Memory While You Sleep - WebMD, 4/24/07
-
High-normal Uric Acid Linked With Mild Cognitive Impairment In The Elderly
- Science Daily, 1/3/07 - "older
people with serum (blood) uric-acid levels in the high end of the normal
range are more likely to process information slowly and experience failures
of verbal and working memory ... Higher levels of uric acid are linked with
known risk factors for dementia, including high blood pressure,
atherosclerosis, Type 2 diabetes and the "metabolic syndrome" of abdominal
obesity and insulin resistance"
- Virus may
affect memory years later - MSNBC, 10/23/06 -
"A family of viruses that cause a
range of ills from the common cold to polio may be able to infect the brain
and cause steady damage"
-
Is Cholesterol a Memory Thief? - Geriatrics and Aging, Volume 9, Number
7, JulyAugust 2006, Pages 484-490 -
"Emerging data indicate that circulating cholesterol levels may influence
progression of the dementing disorder. A recent pilot, proof-of-concept,
placebo-controlled clinical trial suggests that the cholesterol-lowering
medication atorva-statin provides benefit in treating mild-to-moderate AD.
Although not approved for the treatment of AD, statin therapy might be
considered in the setting of elevated cholesterol levels--even when LDL/HDL
ratios are acceptable"
-
Insulin Sensitizers Cut Cognitive Decline in AD - Clinical Psychiatry
News, 4/06 - "There is a critical
relationship between insulin resistance and key aspects of brain function
... patients taking
rosiglitazone performed significantly better than those taking placebo
on a delayed memory task (the Buschke Selective Reminding Test)" -
See OffshoreRX.com
.
-
Less Cognitive Impairment Seen in Women Taking Drug for Osteoporosis -
Doctor's Guide, 4/7/05 - "The drug,
raloxifene, modulates
the activity of the hormone estrogen ... the 120 mg dose conferred a 33%
lower risk of developing mild cognitive impairment when compared with the 60
mg dose and with placebo. The 60 mg dose offered no apparent prevention of
cognitive impairment. While researchers also observed a reduced risk of
developing Alzheimer's disease, that reduction was of borderline statistical
significance"
-
Homocysteine and cognitive function - Medscape, 3/25/05 -
"Higher
homocysteine levels were associated with
worse function across a broad range of cognitive domains, and the magnitude
of the associations was large. The data suggest that homocysteine may be a
potentially important modifiable cause of cognitive dysfunction"
- Healthy Midlife Heart Lowers Dementia Risk - WebMD, 1/24/05 -
"Middle-aged people with high blood pressure, high cholesterol, and diabetes are 20%-40% more
likely to develop dementia in old age"
-
CV Risk Factors May Be Bad for Brain, as Well as Heart - Clinical Psychiatry News, 12/04 -
"Dyslipidemia,
obesity, and hypertension aren't just bad for the heart. They're bad for the brain, too ... women in the highest versus the lowest quintiles for HDL were 2 years younger. … Simple lifestyle changes that increase HDL cholesterol may have a substantial health impact"
- Metabolic Syndrome Can Reduce Mental Function - WebMD, 11/9/04 -
"those with metabolic syndrome were 20% more likely to
develop a decline in mental function compared with a group of elderly people without metabolic syndrome"
- Metabolic Syndrome Associated with Cognitive Decline in Elderly Persons - Doctor's Guide, 11/9/04 -
"persons with the
metabolic syndrome (n = 1016) were 20 percent more likely to develop cognitive impairment ... Those with both metabolic syndrome and high inflammation (n = 348) were 66 percent more likely to have cognitive impairment than those without the metabolic
syndrome"
- High-fat Diets Hammer Memory, More Than A Waistline Worry - Science Daily, 11/3/04 -
"the mice on the high-fat and high-fat, high-sugar
diets could not learn and remember the maze as well as those on the other diets"
- Low Testosterone Linked With Memory Loss - WebMD, 10/27/04
- Testosterone Deprivation Makes Men Forget - Science Daily, 10/22/04 -
"word retention drops sharply after only two minutes among men
undergoing testosterone deprivation therapy"
- Specific Type of Cognition Improves with Hormone Replacement in Postmenopausal Women - Doctor's Guide, 6/24/03 -
"The
oestrogen therapy had no effect on overall verbal recall; however, it reduced perseverative errors -- the repetition of words already recalled -- by almost half.
Perseveration is an important part of verbal learning, representing either inability to inhibit a previously stated response or true forgetting that a response was already given"
- Tests that Measure Learning and Recall Most Likely to Predict Mild Cognitive Impairment - Doctor's Guide, 4/8/03
- Total Recall - The future of memory. By David Plotz - MSNBC, 3/11/03
- Alzheimer's, Dementia Not Inevitable With Age - WebMD, 2/11/03 -
"In their study, fully one-half of the 111 nonagenarians -- people 90-99 years old --
had no signs of clinically measurable memory loss, while another 12% had only mild cognitive impairment. Only about one in three had dementia ... One of the things that struck me is that most of the people we studied who lived into their 90s -- whether or not they had dementia -- had
at least one parent who lived into their 80s or 90s ... And while some were obese, the vast majority of the study participants and those who had no signs of memory loss were thin"
- High Blood Sugar Linked To Lost Memory - Intelihealth, 2/4/03
- Brain Feedback May Improve Memory - WebMD, 1/27/03
- Can a Good Memory Be Inherited? - WebMD, 1/24/03
-
Statin Therapy Does Not Slow Cognitive Decline - Clinical Psychiatry News, 1/03 -
"pravastatin
showed no effect at all on cognition in PROSPER. Similarly, simvastatin exerted no impact upon cognitive decline in the earlier 20,536-patient randomized double-blind Heart Protection Study ... It might be better to look at the use of
antihypertensives
in the elderly to prevent cognitive decline” based upon accumulating extremely promising clinical trials data on that score ... Prior statin trials in middle-aged patients have shown stroke prevention but not until after 5-6 years of treatment"
-
Mild Cognitive Impairment Is Widespread - Clinical Psychiatry News, 11/02
- Forgetfulness Is No Laughing Matter - WebMD, 9/27/02
- Scientists Improve Memory In Mice By Turning Off Enzyme [PP1] - Intelihealth, 8/28/02
- Mini-Mental Test Helps Spot Alzheimer's Versus Dementia With Lewy Bodies - Doctor's Guide, 6/12/02
- Statins May Preserve Brain Power - WebMD, 3/18/02 -
"The study also found that statin use was associated with a lower risk of memory problems or dementia, regardless of total
cholesterol level. The authors say more research is needed to understand exactly how statins seem to protect the brain, but they suspect that the drugs may work by improving muscle function and reducing inflammation"
- Endogenous Estradiol in Elderly Individuals: Cognitive and Noncognitive Associations - Archives of Neurology, 3/02 -
"Lower E2
[estradiol] levels are correlated with poor cognitive, behavioral, and functional status in older individuals"
- Moderate Alcohol Use By Seniors May Curb Cognitive Impairment - Doctor's Guide, 1/15/02
- Estrogen Patch May Improve Memory for Women with Alzheimer's - Doctor's Guide, 8/27/01
- Estrogen Patch Found to Improve Memory - WebMD, 8/27/01 -
"after two months of wearing an estrogen patch, postmenopausal women with mild to moderate
Alzheimer's disease showed some improvement in both memory and thinking ability"
- Older Women Who Keep Active Have Lower Risk for Mental Decline - WebMD, 5/9/01 -
"women who walked the most were the least likely to suffer a decline in thought processes and that there was a direct
relationship between activity and mental function: As the amount of walking or calories burned per week rose, the risk for loss of mental abilities declined"
- New Alzheimer Guidelines Issued - Intelihealth, 5/8/01 -
"People diagnosed with persistent short-term memory loss have an increased risk of developing Alzheimer's disease and
should be aggressively monitored by their physicians"
- Cholesterol drug may prevent Alzheimer's - CNN, 5/1/01 -
"What we found was that patients taking statins have a
60 to 70 percent reduction in the risk of Alzheimer's disease"
- Decreased Memory After Age 60 Linked To High Homocysteine Levels - Doctor's Guide, 4/26/01 -
"High circulating levels of homocysteine, especially with increasing age, have
been associated with cognitive impairment. In recent studies, Alzheimer disease and dementia after multiple strokes have been linked to extremely high serum homocysteine concentrations ... The folate status of the participants was an important consideration
because folate has been shown to significantly modify homocysteine levels"
- Researchers Find Link For Estrogen's Power To Protect The Brain - Intelihealth, 4/12/01 -
"Dubal used female rats whose ovaries were surgically removed - thereby eliminating
estradiol production - and induced strokes in the animals by blocking an artery carrying blood to the brain. The rats given supplemental estrogen had far less brain damage than those from whom the hormone supplement was withheld"
- Don't Chalk Forgetfulness Up to Normal Aging, Memory Loss May Really Be a Sign of Early Alzheimer's - WebMD, 3/14/01 -
"older people who have repeated memory lapses may actually have an early form
of Alzheimer's disease, even if they do not have the dementia characteristic of the disease"
- Scientists Can Make Mice Smarter -- Are We Next? - WebMD, 3/8/01 -
"A complex chain of enzymes in the brain normally limits the amount of memories that can be stored ... Removing these inhibitory
constraints can enhance ... learning and can lead to an improvement in certain aspects of memory storage ... Combined with earlier studies, our work clearly shows that calcineurin is involved in learning and memory ... behavioral changes related to learning involve strengthening the connections between nerve cells
rather than changing the way nerve cells are hard-wired together"
- Male Brains Need Estrogen for Good Memory - WebMD, 11/7/00
- Estrogen Therapy May Help Prevent Memory Decline In Elderly Women - Doctor's Guide, 10/11/00
- Boost Your Memory - WebMD, 10/9/00
- Male Hormone May Improve Some Memory For Women - WebMD, 8/24/00
- Estrogen Replacement May Stimulate Blood Flow To The Brain, Improve Memory - Doctor's Guide, 6/28/00
- How to Grow Old Successfully - WebMD, 6/26/00
- Neuroscience finds foggy link between depression and memory loss - CNN, 4/18/00
- Social and Intellectual Stimulation May Prevent Memory Loss - WebMD, 4/13/00
- Possible Link Found Between Tamoxifen, Memory Loss - Doctor's Guide, 10/15/99
- Some SSRIs May Impair Vigilance And Long-Term Memory - Doctor's Guide, 9/27/99
- Risperidone Reduces Aggression and Agitation in Patients with Severe Dementia - Doctor's Guide, 9/22/99
- Depression Commonly Misdiagnosed As Dementia - Doctor's Guide, 9/13/99
- Smoking Doubles Risk Of Dementia And Alzheimer's Disease - Doctor's Guide, 6/19/98
- Estrogen Replacement May Help Slow Decline In Memory - Doctor's Guide, 12/22/97
- Study Links Between Calcium Blockers And Brain Damage, Memory Loss - Doctor's Guide, 12/2/97
- Effects Of Dopamine-Like Drug Enhances Short-Term Memory, Up To A Point - Doctor's Guide, 11/21/97
- New Study Finds Substance That Helps Working Memory Work Better - Doctor's Guide, 6/10/97
Related Searches:
Recommended Books:
70215
|