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Home > Anti-aging Research > HRT > Premarin

Premarin (conjugated estrogens or estrogen cream)

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News & Research:

  • Study Favors Premarin for Osteoporosis - HealthDay, 4/26/04 - "three-year study ... Bone density declined by 2 percent in the placebo group, remained stable in the two raloxifene groups, and increased by 4.6 percent in the CEE group"
  • FDA Approves Low Dose Premarin (Conjugated Estrogens Tablets) - Doctor's Guide, 4/28/03 - "Premarin® (conjugated estrogens tablets, USP) 0.45 mg contains 28 percent less estrogen than the standard 0.625 mg dose. Premarin 0.45 mg was approved for the treatment of moderate to severe vasomotor symptoms associated with menopause and the treatment of moderate to severe symptoms of vulvar and vaginal atrophy"
  • Estradiol Alone Does Not Increase Breast Cancer Risk - Doctor's Guide, 12/16/02 - "Hormone replacement therapy containing progestins significantly elevates breast cancer risk, but preparations containing estradiol alone do not, a large Swedish observational study suggests"
  • Are there any side effects to using the estrogen ring - Dr. Weil, 8/2/02 - "clinical trials showed only mild and transient vaginal discomfort, irritation or abdominal pain. Of more concern to some women is whether estrogen from the ring (and the creams) can be absorbed into your bloodstream and carried elsewhere in the body. This may not be a major problem. Studies have shown that when the vaginal lining has thickened in response to the hormone, it becomes more difficult to penetrate, reducing absorption of topical estrogen into the body"

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