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Home > Health Conditions > White Coat Hypertension

White Coat Hypertension

News and Research:

• Treatment of white coat hypertension with metformin - Int Heart J. 2008 Nov;49(6):671-9 - "White coat hypertension (WCH) is most likely a disorder associated with metabolic syndrome ... Twenty-five cases (14.7%) stopped metformin therapy due to excessive anorexia. At the end of a 6-month period, there were highly significant differences between the two groups with respect to the prevalences of resolved WCH, hyperbetalipoproteinemia, hypertriglyceridemia, dyslipidemia, overweight and obesity, and decreased fasting plasma glucose below 110 mg/dL ... Thus, the management of WCH should not focus solely on the regulation of blood pressure with antihypertensive medications, but rather on the prevention of future excess weight and various associated disorders, and metformin alone is an effective therapeutic option, most likely due to its powerful inhibitory effect on appetite"
• 'White Coat Effect' Linked to Hypertension Overtreatment - WebMD, 6/21/11 - "the stress of a medical exam can cause large elevations in blood pressure ... the new research highlights the largely unrecognized risk of treating patients too aggressively based on falsely high blood pressure readings"

Abstracts:

• Can blood pressure measurements taken in the physician's office avoid the 'white coat' bias? - Blood Press Monit. 2011 Sep 3 - "physician's clinic (CBP) ... ambulatory (ABP) and home (HBP) monitoring ... nonclinical setting by trained technicians (NCBP) ... Multiple regression analysis showed that HBP and NCBP (P<0.001) explained 94 and 87% of the variance in systolic and diastolic ABP, respectively. The agreement between NCBP and ABP was greater than that between CBP and ABP or between HBP ... When ABP monitoring and HBP monitoring are not options, the NCBP at the clinic can avoid the white coat bias and therefore improve diagnosis"