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Home > Anti-aging Research > Maca

Maca (Lepidium meyenii)

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  • Inflammatory pathway employed by Red Maca to treat induced benign prostatic hyperplasia in rats - Andrologia. 2020 Jan 28 - "The Peruvian plant known as Red Maca (RM) (Lepidium meyenii) inhibits BPH in rats and mice. The aim of the study was to assess the inflammatory effect of RM and finasteride in rats with testosterone enanthate (TE)-induced BPH. Thirty rats were divided into 5 groups: Control, TE (50 mg/rat), TE + F (0.6 mg/kg), and two groups of TE + RM 40/80 (40 or 80 mg). After treatments, tumour necrosis factor alpha (TNFa), interleukin 4 (IL4) and interferon gamma (INFg) as well as testosterone and oestradiol were evaluated and inflammatory cells (neutrophils, mast cells and lymphocytes) in prostate were quantified. Red Maca and finasteride treatments decreased inflammatory cells counts in prostate, inhibiting TNFa by different pathways. Finasteride increased IL4 whereas Red Maca increased INFg. In conclusion, data suggest that finasteride acts on Th2 response by increasing IL4 in prostate, while Red Maca acts on Th1 response mediated by INFg" - See Red Maca (RM) (Lepidium meyenii) at Amazon.com.
  • The Effects of Lepidium Meyenii on Grip Strength, Fatigue, and Sexual Behavior - J of Exec and Nutri, 3/19 - "Males in the treatment group showed significant improvements over the placebo group in fatigue (mean±SD: -3.3 ± 3.9 vs. 1.3 ± 6.2), handgrip (4.6 ± 7.5 vs. -0.4 ± 5.4), and sexual behavior (3.83 ± 4.3 vs. 0.7 ± 2.1). Conclusions: Maca supplementation may lessen fatigue, improve strength, and enhance sexual functioning in otherwise healthy men" - [Nutra USA] - See maca extract at Amazon.com.
  • Long-term feeding of hydroalcoholic extract powder of Lepidium meyenii (maca) enhances the steroidogenic ability of Leydig cells to alleviate its decline with ageing in male rats - Andrologia. 2017 Mar 10 - "Overall testosterone production by cultured Leydig cells decreased to about a half from 35 to 48 weeks of age. These results suggest that feeding the maca extract for a long time to male rats may enhance the steroidogenic ability of Leydig cells to alleviate its decline with ageing, whereas it may cause only a transient increase in blood testosterone concentration in sexually maturing male rats"