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Guarana

Specific Recommendations:

• guarana at Amazon.com

News & Research:

• Guarana intake associated with reduction in metabolic disorders: Study - Nutra USA, 3/2/11
• Novel Method of Enhancing Anti-Fat Effects of CLA - Life Extension Magazine, 8/02 - "The results of this study demonstrate that dietary CLA decreases excess fat accumulation by reducing the capacity of adipocytes to store fat. When guarana is added to CLA, there is an additional effect of reduction in adipocyte number, as well as a decrease in adipocyte size. The impact of this finding in preventing obesity is profound ... CLA improves insulin sensitivity ... Guarana is an herb that contains a form of caffeine called guaranine, which is 2.5 times stronger than the caffeine found in coffee, tea and soft drinks ... Caffeine accelerates the effectiveness of CLA, thus making CLA a more potent fat burner" - See iHerb CLA products.

Abstracts:

• Alterations in Bacterial Metabolism Contribute to the Lifespan Extension Exerted by Guarana in Caenorhabditis elegans - Nutrients 2022 May 9 - "Guarana (Paullinia cupana) is a widely consumed nutraceutical with various health benefits supported by scientific evidence ... guarana was found to decrease E. coli folate production, revealing one possible route for its beneficial effects" - See guarana at Amazon.com.
• Guaraná, a Highly Caffeinated Food, Presents in vitro Antitumor Activity in Colorectal and Breast Cancer Cell Lines by Inhibiting AKT/mTOR/S6K and MAPKs Pathways - Nutr Cancer. 2017 Jun 1:1-11 - "Guaraná decreased the colony formation and cell growth in MCF-7 and HT-29 cells. Guaraná did not affect normal cells. In conclusion, guaraná could be an important agent in antitumor pharmacologic therapies by inhibiting the mTOR and MAPKs pathways"
• Heart Rate Variability and Cognitive Function Following a Multi-Vitamin and Mineral Supplementation with Added Guarana (Paullinia cupana) - Nutrients. 2014 Dec 31;7(1):196-208 - "The aim of this study was to assess cognitive performance and heart rate variability (HRV) following the ingestion of either a multi-vitamin-mineral preparation supplemented with 300 mg guarana (Ac); a caffeine supplement (C) or a placebo supplement (Pl) ... The results suggest that the ingestion of a multi-vitamin-mineral with added guarana improves decision-making performance and is accompanied by a stable autonomic nervous system regulation during the first hour"