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Home > Anti-aging Research > Glucarate

Calcium D-glucarate

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Abstracts:

  • Modulation of carcinogen metabolism and DNA interaction by calcium glucarate in mouse skin - Toxicol Sci. 2004 May;79(1):47-55. Epub 2004 Feb 19 - "Cag exerted its antitumor effect possibly by inhibiting the carcinogen-DNA binding, which appears to be due to reduced DNA synthesis and AHH activity"
  • Detoxifying cancer causing agents to prevent cancer - Integr Cancer Ther. 2003 Jun;2(2):139-44 - "There is now growing evidence for the possible control of different stages of the cancer induction by inhibiting beta-glucuronidase with D-glucaric acid derivatives, especially with its salts (D-glucarates) ... the consumption of fruits and vegetables naturally rich in D-glucaric acid or self-medication with D-glucaric acid derivatives such as calcium D-glucarate offers a promising cancer prevention approach"
  • Calcium glucarate prevents tumor formation in mouse skin - Biomed Environ Sci. 2003 Mar;16(1):9-16 - "antitumorigenic effect of Cag is considered to be possibly due to stimulation of differentiation and suppression of proliferation"