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Recent Longevity News for the
seven days ending 2/22/12. You should consult your doctor if you are
taking any medications.
Fructose off the Hook for Overweight and Obesity? - WebMD, 2/20/12 -
"The remaining 10 studies under review were based around
adding calories. In each, half of the participants ate their usual diet, while
the other half added fructose, a naturally occurring sweetener, to what they
normally ate. The fructose groups did gain weight, but no more than would be
expected from the amount of additional calories -- or energy -- that they took
in as part of the studies ... Our data suggests that fructose plays the same
role as any energy-dense substance"
The Body Odd - What's the lifespan of a singer's voice? - MSNBC, 2/17/12 -
"vocal cords stiffen with age ... As the vocal membranes
are used more, they become fibrous and stiff with a diminished amplitude of
vibration" - Note: When I get the yearly checkup from my throat cancer,
they stick a scope up your nose all the way down to your vocal cords and tell
you to say “eeee”. One doc remarked how strong my vocals were. I do
karaoke a lot so it would seem to throw out this theory.
Clinical trial supports CLA’s weight management in obese Chinese - Nutra
USA, 2/17/12 - "Twelve weeks of supplementation produced
an average 0.7 kg decrease in body weight and an average decrease in total
body fat of 0.6 kg ... milk supplemented
with CLA (3.4 g/d for 12 wk) ... used the Tonalin
branded ingredient from BASF" - [Abstract]
conjugated linoleic acid at Amazon.com.
Catechin-enriched green tea shows fat busting potential: RCT - Nutra USA,
2/17/12 - "Visceral fat
levels decreased by 9.5 cm2 after twelve weeks of consuming the
catechin-enriched beverage, compared with a control beverage with normal levels
green tea catechins" - See
green tea extract at Amazon.com.
food sweetener may be a hidden source of dietary arsenic - Science Daily,
2/16/12 - "Of the 17 toddler milk formulas tested, only
two had listed organic brown rice syrup as the primary ingredient. These two
formulas, one dairy-based and one soy-based, were extremely high in arsenic,
more than 20 times greater than the other formulas. The amount of inorganic
arsenic, the most toxic form, averaged 8.6 ppb for the dairy based formula and
21.4 ppb for the soy formula"
Flu may boost Alzheimer's risk, research suggests - MSNBC, 2/16/12 -
"Viruses such as
influenza and herpes may leave brain cells vulnerable to degeneration later in
life, and increase the risk of developing diseases such as
Alzheimer's and Parkinson's, research
suggests. That's because these the viruses can enter the brain and trigger an
immune response — inflammation — which can damage brain cells"
mouth, smoking zaps healthy bacteria - Science Daily, 2/15/12 -
"They need a more aggressive form of treatment, because
even after a professional cleaning, they're still at a very high risk for
getting these pathogens back in their mouths right away"
Glass half empty: Is your tap water safe? - MSNBC, 2/15/12 -
"Barium, chromium, copper, lead, nitrate, and other
chemicals, as well as E. coli (E. coli!?), have been detected over the past year
... Antibiotics, hormones, a cancer drug, a chemical found in gasoline,
antiseizure medication...research shows that hundreds of unregulated
contaminants may be flowing from my tap ... a reverse-osmosis system filters out
many EPA-regulated contaminants; and an ultraviolet filter kills bacteria and
other microorganisms" - See
water distillers at Amazon.com.
‘New Car Smell’ Toxic? - WebMD, 2/15/12 - "new car
smell comes from
toxic chemicals off-gassing in a car’s interior,
like brominated flame retardants (BFRs), chromium, and lead ... At the top of
the list for the most healthy car interior is the 2012 Honda Civic ... At the
bottom of the list are the 2011 Mitsubishi Outlander Sport and 2011 Chrysler 200
Abstracts from this week's
Doctor's Guide Nutrition/Dietetics
plus abstracts from my RSS feeds (Click here
for the journals, the PubMed ones at the top):
intake in a large cohort of patients with nonalcoholic fatty liver disease -
Am J Clin Nutr. 2012 Feb 15 - "Decreased
choline intake is significantly associated with
increased fibrosis in postmenopausal women with NAFLD" - See
citicholine at Amazon.com.
consumption and risk of chronic disease in the European Prospective
Investigation into Cancer and Nutrition (EPIC)-Germany study - Am J Clin
Nutr. 2012 Feb 15 - "A lower risk of T2D was associated
with caffeinated (HR: 0.77; 95% CI: 0.63, 0.94; P-trend 0.009) and decaffeinated
(HR: 0.70; 95% CI: 0.46, 1.06; P-trend: 0.043) coffee consumption (≥4 cups/d
compared with <1 cup/d), but cardiovascular disease and cancer risk were not"
consumption in relation to mortality from cardiovascular disease among Japanese
men and women - Eur J Clin Nutr. 2012 Feb 15 -
"Moderate meat consumption, up to ~ 100 g/day, was
not associated with increased mortality from ischemic heart disease,
stroke or total
among either gender"
and A1c Relationship in the National Health and Nutrition Examination Survey
(NHANES) 2003-2006 - J Am Coll Nutr. 2011 Dec;30(6):477-83 -
"The consumption of foods high in vitamin C has
been associated with lower risk of diabetes ... Vitamin C concentrations were
inversely associated with A1c (p = 0.0202).
Stronger inverse associations were observed in subjects 18-44 years of age (p =
0.0017), as well as in female (p = 0.0035) and Mexican American (p = 0.0149)
subgroups. Evidence of a significant interaction between vitamin C and vitamin D
was noted in subjects aged 18-44 years and in females (p = 0.0073 and 0.0095
respectively), with the inverse association tending to be evident at lower
levels of vitamin D"
Neat Tech Stuff / "How To's":
Health Focus (Hair
Ginseng Rhizome and Ginsenoside Ro on Testosterone 5α-Reductase and Hair
Re-growth in Testosterone-treated Mice - Phytother Res. 2011 May 2 -
"Extracts of red ginseng rhizome showed greater
dose-dependent inhibitory effects against testosterone 5α-reductase (5αR) when
compared with extracts of the main root. Ginsenoside Ro, the predominant
ginsenoside in the rhizome, and ginsenoside Rg(3) , a unique ginsenoside in red
ginseng, showed inhibitory activity against 5αR with IC(50) values of 259.4 and
86.1 µm, respectively. The rhizome of P. japonicus, which contains larger
amounts of ginsenoside Ro, also inhibited 5αR. Topical administration of
extracts of red ginseng rhizomes (2 mg/mouse) and ginsenoside Ro (0.2 mg/mouse)
to shaved skin inhibited hair re-growth suppression after shaving in the
testosterone-treated C57BL/6 mice. These results suggest that red ginseng
rhizomes containing both oleanane- and dammarane-type ginsenosides are a
promising raw material for cosmetic use. This is the first report that
ginsenoside Ro enhances in vivo hair re-growth based on their inhibitory
activity against 5αR in the androgenetic alopecia model" - See
ginseng at Amazon.com.
Treating Hair Loss Naturally - WebMD -
"Daly says he routinely recommends up to 3 mg of
biotin daily for his hair loss patients, while Lessman developed a healthy
hair, skin, and nails product containing 2 mg of biotin per daily dosage,
which he believes is the minimum for healthy hair"
Nizoral Shampoo for Hair Loss
- DermaDoctor.com - "They found that Nizoral
increased hair thickness and decreased hair shedding, whereas the zinc
pyrithione shampoo had the opposite effect" - See
Nizoral Shampoo at drugstore.com
Can Lasers Zap Baldness? One Woman Thinks So - CBS Chicago, 2/11/11 -
NEW iGrow Laser Hair Rejuventation System for Home Use - Physician Supported
Click here for the press release.
Hair loss in
long-term or home parenteral nutrition: are micronutrient deficiencies to blame?
- Curr Opin Clin Nutr Metab Care. 2010 Sep 4 - "A serum
ferritin level of 70 mug/l should be targeted when hair loss is unexplained"
Slow Fe Slow Release Iron Tablets 90-Count Box at Amazon.com.
Snack Size Science: Vitamin E and the quest for thick hair - Nutra USA,
5/5/09 - "The experiments used Carotech’s Tocomin
SupraBio ingredient, which contains vitamin E in its tocotrienol forms.
Vitamin E comes in eight forms, including four types of tocopherols, and
four types of tocotrienols ... According to the company, the Malaysian
researchers observed significant hair re-growth of about 42 per cent in the
tocotrienol group, with eight volunteers experiencing greater than 50 per
cent hair growth. No one in the placebo group experienced any hair growth
Jarrow FamilE (contains all eight members of the vitamin E family, includes
Tocomin) at Amazon.com.
Vitamin E may reverse male pattern baldness: Study - Nutra USA, 4/28/09
- "Volunteers were randomly assigned to the palm
tocotrienol complex (total tocotrienol intake of 100 mg) or the placebo
(soft gelatin capsule containing 600 mg soy bean oil) ... Hair counts,
measured by the counting the number of hairs in a pre-selected 2x2 cm area,
were found to significantly increase by an average of 41.8 per cent in the
tocotrienol group, with eight volunteers experiencing greater than 50 per
cent hair growth ... There are eight forms of vitamin E: four tocopherols
(alpha, beta, gamma, delta) and four tocotrienols (alpha, beta, gamma,
delta). Alpha-tocopherol is the main source found in supplements ... While
the majority of research on vitamin E has focused on alpha-Toc, studies into
tocotrienols account for less than one per cent of all research into vitamin
E" - See
Jarrow FamilE (contains all eight members of the vitamin E family, includes
Tocomin) at Amazon.com.
An Herbal Solution to Baldness? - Dr. Weil, 4/24/08
Effect of Dietary
Supplementation With INVERSION(R) Femme on Slimming, Hair Loss, and Skin and
Nail Parameters in Women - Adv Ther. 2007 Sep-Oct;24(5):1154-71 -
"Weight reduction and slimming were measured after
INVERSION Femme was taken for 28 and 58 d. All women showed significant
reductions in weight, body fat, and thigh circumference. During the second
month of treatment, subjects showed an average 50% reduction in hair loss"
Low Iron Could Help Spur Baldness - HealthDay, 5/31/06 -
"Iron deficiency is the world's most common
nutritional deficiency ... If iron deficiency is detected and treated in the
early stages, patients may be able to grow hair more effectively"
Hair Loss? It May
Be Iron Deficiency - WebMD, 5/17/06 -
"whatever the cause of hair loss -- for both women
and men -- having too little iron in the blood makes it worse"
Flax lignans: a cure for hair loss? - Nutra USA, 5/9/05 -
"Ten male sufferers of androgenetic alopecia aged
between 20- and 70- years received a 50mg daily dose of SDG in the form of
one 250 mg capsule of Acatris’ LinumLife Extra ... eight of the participants
reported a modest improvement in their hair loss condition, one reported a
great improvement and one reported no effect at all" - See
Omega-3 fatty acids might curb hair loss - azcentral.com, 4/12/05
Reversing Hair Loss? - Dr. Weil, 6/22/04 -
"you may be able to prevent further loss and
encourage re-growth by including omega-3 fatty acids to your diet"
Soy: Prevent Prostate Cancer, Male Baldness? - WebMD, 3/30/04 -
"A little-known molecule called equol ... is showing
promise as a powerful blocker of a potent male hormone involved in prostate
cancer, male baldness, even acne ... Actually, the protective effects occur
when two chemicals in soy protein -- genistin and daidzin -- reach the
digestive system, Setchell explains. There, they are metabolized to form
genistein and daidzein. Daidzein is metabolized once again, to form equol"
Laser Comb [Hairmax] May Stimulate Hair Growth - thesandiegochannel.com,
""In our clinical trials in Canada, (the comb) does
both," said Dr. Martin Unger, plastic surgeon. "We are getting over 97
percent -- sorry, 95 percent -- of the people who are using this are either
stopping their hair loss or regrowing hair, and over 75 percent of the
patients regrew hair to a significant amount." ... The Hairmax laser
comb costs about $700." - See
HairMax at drugstore.com
Laser Comb May Stimulate Hair Growth - NBCSandiego.com, 5/8/03
- Can I
Stop My Hair from Thinning? - Dr. Weil, 9/13/02 -
"Make sure you’re getting enough
omega-3 fatty acids ... supplement your
GLA (gamma-linolenic acid) in
the form of black currant oil or
evening primrose oil"
Natural Treatment for Male Pattern Baldness - New Hope Natural Media,
"Those with male pattern baldness may increase hair
growth by taking a preparation containing
saw palmetto (Serenoa repens) and
beta-sitosterol ... Conventional
medicines used to treat male pattern baldness are designed to block the
conversion of testosterone to DHT. Topical application of minoxidil
(Rogaine®) and taking oral finasteride (Propecia®) have been shown to
inhibit this conversion and to increase hair growth, but both medications
have been linked with several adverse side effects, including fast heart
rate, headaches, impotence, and decreased libido ... 400 mg of a
standardized extract of saw palmetto and 100 mg of beta-sitosterol per day
... After about five months, hair growth in 60% of the men taking the herbal
combination had improved compared with their initial evaluation. In
contrast, only 11% of those receiving the placebo improved"
Nutritional factors and hair loss - Clinical & Experimental Dermatology,
concentrations were a factor in female hair loss ... The role of the
essential amino acid,
l-lysine in hair loss also appears to be
important. Double-blind data confirmed the findings of an open study in
women with increased hair shedding, where a significant proportion responded
to l-lysine and iron therapy"
Monthly Updates - Hair Loss Research, 10/01 -
"While finasteride (Propecia/Proscar) decreases
serum DHT, it also is thought to increase estrogen which suggests that men
over 35 may want to consider using it in conjunction with a systemic
aromatase inhibitor such as
Arimidex, or stinging nettle extract,
to maximize its hair growth effects and minimize potential side effects
(that are listed in the PDR) such as
(breast enlargement in males), sexual side effects, and an increase in fat
deposition. These compounds have been reliably shown to increase
testosterone and reduce excess estrogen, resulting in a youthful hormone
profile that optimizes immune function and to some degree, body composition"
Antiaging Products for Skin, Hair and Nails - Nutrition Science News,
"A lack of silicon is known to reduce normal growth
and repair of the skin, hair and nails. However, studies show that silicon
supplementation has delivered few benefits. The reason for this in most
cases is that a nonbioavailable silicon source has been used. Silicon is a
nonmetallic element that is very reactive. It occurs naturally almost
exclusively in silicates, the geologic rock-forming minerals. Although
silicates are the most abundant materials on earth, they don't provide a
bioavailable form of dietary silicon. Moreover, silica, often used as a
dietary supplement, is a polymeric silicon-hydroxide-oxide-water complex
from hard stone, such as quartz, that has anywhere from two to trillions of
silicon atoms, and is also very poorly bioavailable. On the other hand,
orthosilicic acid, which consists of only one
Si bonded to four hydroxides instead of oxygen, is the form of Si that is
found in our bloodstream. Therefore, stabilized orthosilic acid is the only
form of supplemental silicon that has been shown conclusively to be
bioavailable for humans. Silicates, silica gel, colloidal silica, clays,
horsetail (Equisetum arvense) and most foods don't contain the orthosilicic
acid form of silicon."
Hair Graying and Loss - Nutrition Science News, 10/00 -
"Japanese researchers found that topical application
of procyanidin-B2 from
grape seed and apple extracts activate hair follicles in mice, resulting
in increased hair growth. Furthermore, Italian researchers found that a
topical preparation containing esculin (an oxolinic acid) from horse
chestnut (Aesculus hippocastanum) reduced hair loss and increased
circulation to the hair follicles in men and women suffering from hair
loss.3 Reduced scalp microcirculation is also one of the factors causing
Essential Oils Can Help Regrow Hair - Nutrition Science News, 9/00
Proanthocyanidin Power - Nutrition Science News, 6/00 -
"Japanese researchers shaved mice and found that 40
percent of their hair grew back naturally. When a 1 percent solution of any
was applied to the skin, however, between 70 and 80 percent of the hair grew
back. Test tube studies confirm that OPCs actually stimulate the hair
keratinocytes to produce three times more hair than the controls."
Hair Loss- MinSaw-A, Nizoral and Dercos- The bald truth! - By Phil
Micans PharmB -
"the addition of retinolic acid (the active
ingredient in the famous anti-wrinkle skin cream-
Retin-A), helps to further stimulate the blood supply on the scalp
surface and therefore to the hair follicle"
for your dome? Drug thickens thin hair - MSNBC, 11/14/11 -
"The appeal of using Latisse for hair loss is its ease
and convenience, as it seems to only require one drop to the affected area once
a day ... The major drawback: It's expensive. Each 2-ounce bottle costs $100 to
$150 — and some patients will run through two or three bottles a month"
Regrowing hair: Researchers may have accidentally discovered a solution -
Science Daily, 2/16/11 - "a short-duration treatment
with this compound causes an astounding long-term hair regrowth in chronically
stressed mutant mice ... the researchers had been using mice that were
genetically altered to overproduce a stress hormone called
corticotrophin-releasing factor, or CRF. As these mice age, they lose hair and
eventually become bald on their backs, making them visually distinct from their
unaltered counterparts. The Salk Institute researchers had developed the
chemical compound, a peptide called astressin-B, and described its ability to
block the action of CRF. Stenzel-Poore had created an animal model of chronic
stress by altering the mice to overproduce CRF ... researchers injected the
astressin-B into the bald mice to observe how its CRF-blocking ability affected
gastrointestinal tract function. The initial single injection had no effect, so
the investigators continued the injections over five days to give the peptide a
better chance of blocking the CRF receptors. They measured the inhibitory
effects of this regimen on the stress-induced response in the colons of the mice
and placed the animals back in their cages with their hairy counterparts ...
About three months later, the investigators returned to these mice to conduct
further gastrointestinal studies and found they couldn't distinguish them from
their unaltered brethren. They had regrown hair on their previously bald backs"
- Note: To the best of my knowledge there's nothing non-experimental on the
market, either conventional or alternative, that inhibits CRF. If there were
people would be taking it to reduce cortisol.
for hair loss and benign prostatic hyperplasia may result in loss of libido,
erectile dysfunction in men - Science Daily, 1/11/11 -
"5a-reductase inhibitors (5a-RIs), while improving
urinary symptoms in patients with benign prostatic hyperplasia (BPH) and
possible hair loss prevention, produces significant adverse effects in some
individuals including loss of libido, erectile dysfunction (ED), ejaculatory
dysfunction and potential depression" - Note: That goes back and forth.
One study claimed that finasteride improved sex after after six months of taking
it. Regarding gynaecomastia, if you're taking low dose letrozole to increase
testosterone and to prevent aromatization it many also help prevent
Prostate Drug May Not Dim Sex - WebMD, 6/26/07 -
"Six months after the men started taking their assigned drugs, the survey
scores were about three points higher for the men taking Proscar. By the end
of the study, that gap narrowed to about two points"
Prostate Drug Doesn't Limit Sexual Function In Most Men - Science Daily,
7/19/07 - "The study suggests that finasteride will
cause little or no sexual dysfunction for most men who decide to take it"
Ask a Medical Question - Can letrozole cure gynecomastia - JustAnswer -
"Letrozole may be effective in preventing and
reversing the gynaecomastia provided it is used early enough in steroid
induced gynaecomastia" - See letrozole at
believe the recommended dose is something like a quarter tablet every three
days but don't quote me on it. That's what I take.
Types of Hair Loss
and Treatment Options, Including Low-Level Light Therapy - Medscape, 10/7/10
Treatment of Hair Loss in Women (June) - Ann Pharmacother. 2010 May 4
Dermatologists Can Help Women Win the Fight Against Common Forms of Hair Loss
- Science Daily, 3/6/10
Shining a Light on 9 Hair Loss
Treatments - ABC News, 7/8/09
Scientists Inch Closer to Figuring Out How Hair Grows - WebMD, 7/31/08
Quick Test May Help Spot Male Hair Loss - WebMD, 6/16/08
To The Roots Of Hair Loss - Science Daily, 2/24/08
Men Who Smoke May Have Increased Risk For Hair Loss - Science Daily,
Treatment Found To Reverse Hair Loss - Science Daily, 6/11/07 -
"one of each pair of twins was given 0.5 mg/day of the
medication, the other receiving a placebo ... After both 6 and 12-month
intervals, hair loss was found to not only have been halted in twins using
dutasteride, but hair growth was actively improved"
- Note: Dutasteride is Avodart®. See dutasteride at
Hair Follicles Created For The First Time, Mouse Study - Science Daily,
Grasping at strands for baldness remedies - USA Today, 3/18/07 -
"So where does the laser comb fit in? Leavitt points
to the six-month study reviewed by the FDA that shows men who used the comb
grew an average of 19 more "terminal" (thick, rather than thin) hairs per
square centimeter than those who used sham devices. That's a "medically
significant" amount, he says, though the average healthy scalp has 160 to
260 hairs per square centimeter" - See the HairMax at
Drug May Fight Women's Hair Loss, Too - WebMD, 3/20/06 -
"Propecia, a drug used to treat male hair loss, may
help fix women's hair loss when taken with birth control pills"
Production rates of testosterone and of dihydrotestosterone in female
pattern hair loss - Metabolism. 2003 Jul;52(7):927-929
A randomized clinical trial of 5% topical minoxidil versus 2% topical
minoxidil and placebo in the treatment of androgenetic alopecia in men -
Journal of the American Academy of Dermatology, 9/02 -
"In men with AGA, 5% topical minoxidil was clearly superior to 2% topical
minoxidil and placebo in increasing hair regrowth, and the magnitude of its
effect was marked (45% more hair regrowth than 2% topical minoxidil at week
48)." - See
5% minoxidil at drugstore.com
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