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Welcome to the Quality Counts. For those health conscious consumers and medical professionals that are looking to purchase nutritional supplements, vitamins, herbs, learning about medications, losing weight, health food, low carbs, high protein nutrition, and exercise, you have come to the right place. Quality Counts serves both the medical practitioner and consumer interested in nutritional therapy and alternative medicine.

Home > Health Conditions > Wrinkles

Wrinkles and other skin damage

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Alternative News:

  • Study unlocks Pycnogenol’s skin health mechanism - Nutra USA, 1/26/12 - "Daily supplements of an extract from French maritime pine bark may boost skin elasticity by 25% and skin hydration by 8% ... the pine bark extract was also associated with a 3% reduction in skin wrinkles" - [Abstract] - See Pine Bark/Pycnogenol products at iHerb.  Some say grape seed extract is the same thing without the patent mark-up.  See OPC + 95 products at iHerb.
  • Antioxidant Micronutrients Improve Intrinsic and UV-Induced Apoptosis of Human Lymphocytes Particularly in Elderly People - J Nutr Health Aging. 2011;15(10):912-917 - "The study was a 2 months, double-blind, randomized trial. Three age groups were studied: children, young adults and elderly people. A total of 274 healthy subjects were allocated to a group supplemented with moderate amounts of retinol, β-carotene, α-tocopherol, ascorbic acid and selenium or placebo ... Young and elderly people have a higher intrinsic apoptosis than children, which was improved by antioxidant supplementation. UV-induced damage was attenuated by the supplementation in all three age groups"
  • Juice concentrates may boost skin-from-within - Nutra USA, 9/14/11 - "Skin hydration improved by 9% while skin thickness increased by 6% following 12 weeks of supplementation with a micronutrient-dense concentrate of a range of fruit and vegetables including cherry, apple, broccoli, cranberry, orange, pineapple, spinach, and tomato ... skin microcirculation also improved by almost 40% following supplementation with the juice concentrate, which could boost the supply of nutrients and oxygen to the skin and thereby boosting health" - [Abstract] - See Garden of Life, Radical Fruits Antioxidant Complex, 60 Caplets.  I'll save you the multi-level-marketing Juice Plus mark-up.
  • Which Foods Can Help Your Skin Look Better - CBS Chicago, 7/14/11 - "Experts say that what you eat has a big effect on how you look ... people who switched to a hypoglycemic – or low sugar – diet for three months reduced their pimples by 20 percent ... So what should we eat to prevent or even get rid of wrinkles? ... What you want to do is build up the collagen and there’s certain collagen builders, such as Vitamin C and Vitamin E ... To avoid dry, flaky skin or eczema, increase your omega 3s ... There’s less scientific proof about cellulite, but many nutritionists also feel you can reduce the appearance of those unsightly bulges by eating dark red and purple foods, which help rid the body of toxins – things like cranberry juice, blueberries, cherries and radicchio lettuce ... If you’re looking for a cure-all for nearly any skin problem, it’s extra virgin olive oil. It helps reduce inflammation, and can help everything from psoriasis to eczema to acne .. dairy, even skim-milk, seems to make nearly every skin problem worse"
  • Green Tea Polyphenols Provide Photoprotection, Increase Microcirculation, and Modulate Skin Properties of Women - J Nutr. 2011 Apr 27 - "Dietary constituents including polyphenols and carotenoids contribute to endogenous photoprotection and modulate skin characteristics related to structure and function of the tissue. Animal and in-vitro studies indicate that green tea polyphenols affect skin properties. In a 12-wk, double-blind, placebo-controlled study, 60 female volunteers were randomized to an intervention or control group. Participants consumed either a beverage with green tea polyphenols providing 1402 mg total catechins/d or a control beverage. Skin photoprotection, structure, and function were measured at baseline (wk 0), wk 6, and wk 12. Following exposure of the skin areas to 1.25 minimal erythemal dose of radiation from a solar simulator, UV-induced erythema decreased significantly in the intervention group by 16 and 25% after 6 and 12 wk, respectively. Skin structural characteristics that were positively affected included elasticity, roughness, scaling, density, and water homeostasis. Intake of the green tea polyphenol beverage for 12 wk increased blood flow and oxygen delivery to the skin. Likewise, in a separate, randomized, double-blind, single-dose (0.5, 1.0, and 2.0 g) study of green tea polyphenols, blood flow was maximized at 30 min after ingestion. In summary, green tea polyphenols delivered in a beverage were shown to protect skin against harmful UV radiation and helped to improve overall skin quality of women" - See Jarrow Green Tea extract at iHerb.
  • Sugar and Your Skin - ABC News, 11/30/10 - It's a video.  He talks about glycation, fish oil, sugar, etc.  Things I've had in my newsletters for years.  See those pages.
  • Association of facial skin aging and vitamin D levels in middle-aged white women - Cancer Causes Control. 2010 Sep 30 - "Adjusting for age and season of blood collection, women with lower photodamage scores were associated with a 5-fold increased odds of being vitamin D insufficient (OR 5.0, 95% CI: 1.1, 23). Low scores for specific photodamage parameters including erythema/telangiectasias, hyperpigmentation, and wrinkling were also significantly associated with vitamin D insufficiency. Our results suggest an association between skin aging and 25(OH)D levels" - See vitamin D products at iHerb.
  • Pomegranate compounds show skin health potential - Nutra USA, 8/10/10 - "ellagic acid may prevent the degradation of collagen in human skin cells, which would maintain skin structure and slow the formation of wrinkles ... Topical or dietary interventions with berries and pomegranate rich in ellagic acid and ellagitannins are promising strategies in curtailing skin wrinkling and cutaneous inflammation associated with chronic UV exposure leading to photoageing" - [Abstract] - See pomegranate juice Extracts at iHerb.
  • Dietary compound ellagic acid alleviates skin wrinkle and inflammation induced by UV-B irradiation - Exp Dermatol. 2010 Aug;19(8):e182-90 - "Ellagic acid, a polyphenol compound present in berries and pomegranate, has received attention as an agent that may have potential bioactivities preventing chronic diseases ... These results demonstrate that ellagic acid prevented collagen destruction and inflammatory responses caused by UV-B. Therefore, dietary and pharmacological interventions with berries rich in ellagic acid may be promising treatment strategies interrupting skin wrinkle and inflammation associated with chronic UV exposure leading to photoageing" - See pomegranate juice Extracts at iHerb.
  • Clinical evidence of skin benefits of a dietary supplement containing probiotic and carotenoids on UV- induced damage - Br J Dermatol. 2010 Jun 9 - "Lactobacillus johnsonii (La1) ... dietary supplement (DS) combining La1 and nutritional doses of carotenoids ... A 10 week DS intake prevented the UV-DL induced decrease in Langerhans cell density and the increase in Factor XIIIa+ type I dermal dendrocytes while it reduced dermal inflammatory cells. Clinical and instrumental MED rose by 20% and 19% respectively, and skin colour was intensified, as shown by the increase in DeltaE parameter. The efficacy of DS was confirmed by dermatologists and subjects in real conditions of use. Conclusion: Nutritional supplementation combining a specific probiotic (la1) and nutritional doses of carotenoids reduced early UV-induced skin damage caused by simulated or natural sun exposure in a large panel of subjects (n=139). Altogether, these results support the use of this nutritional supplement for a global approach in photoprotection, in combination with a sunscreen" - See probiotic products at iHerband Nature's Way, Multi-Carotene Anti-oxidant at iHerb.
  • Turmeric Cream Decreases Signs of Aging - Medscape, 3/16/10 - "A new moisturizing cream containing turmeric extract, an ingredient found in curry, significantly improves the appearance of facial spots, fine lines, and wrinkles, according to results from 2 split-face studies (1 with an all-white and 1 with an all-Asian patient population) presented here at the American Academy of Dermatology 68th Annual Meeting" - See curcumin/turmeric products at iHerb.
  • Association of dietary fat, vegetables and antioxidant micronutrients with skin ageing in Japanese women - Br J Nutr. 2010 Jan 20:1-6 - "The extent of facial wrinkles in the crow's-foot area was determined by observation using the Daniell scale. Each subject's usual diet was determined with the use of a validated FFQ. After controlling for covariates including age, smoking status, BMI and lifetime sun exposure, the results showed that higher intakes of total fat, saturated fat and monounsaturated fat were significantly associated with increased skin elasticity. A higher intake of green and yellow vegetables was significantly associated with a decreased Daniell wrinkling score. Intake of saturated fat was significantly inversely associated with the Daniell wrinkling score after additional adjustment for green and yellow vegetable intake"
  • Microdermabrasion May Rejuvenate Aging Skin - WebMD, 10/20/09
  • New Role Of Vitamin C In Skin Protection; Relevance To The Cosmetics Industry - Science Daily, 9/8/09 - "a form of Vitamin C helped to promote wound healing and also helped protect the DNA damage of skin cells ... Previously, the group has published evidence that DNA repair is upregulated in people consuming vitamin C supplements ... The results demonstrated that vitamin C may improve wound healing by stimulating quiescent fibroblasts to divide and by promoting their migration into the wounded area. Vitamin C could also protect the skin by increasing the capacity of fibroblasts to repair potentially mutagenic DNA lesions ... Free radicals are associated with premature skin aging, and antioxidants, such as vitamin C, are known to counter these highly damaging compounds. This new evidence suggest that, in addition to ‘mopping up’ free radicals, vitamin C can help remove the DNA damage they form, if they get past the cell’s defences"
  • Dysport Deemed Safe, Effective Anti-wrinkle Treatment, Plastic Surgeons Say - Science Daily, 8/3/09
  • Hydrolysed collagen may boost beauty from within: Rousselot studies - Nutra USA, 5/7/09 - "According to the company, women receiving the collagen supplement experienced a 28 per cent improvement in the skin hydration levels, compared to placebo, with 91 per cent of these women reporting increased skin hydration levels after eight weeks ... Furthermore, the number of micro-relief furrows and deep wrinkles decreased by 26 and 30 per cent, compared with the placebo group" - See collagen products at iHerb.
  • Anti-ageing Cosmetic Reduced Wrinkles In Clinical Trial - Science Daily, 4/28/09 - "the cosmetic, No7 Protect & Perfect Intense Beauty Serum, could improve some of these clinical features ... 70% of individuals using the beauty product had significantly fewer wrinkles after 12 months of daily use compared to volunteers using a placebo" - Note:  The best I could figure is that it is only sold in England.
  • Antioxidant Found In Berries, Other Foods Prevents UV Skin Damage That Leads To Wrinkles - Science Daily, 4/21/09 - "Using a topical application of the antioxidant ellagic acid, researchers at Hallym University in the Republic of Korea markedly prevented collagen destruction and inflammatory response – major causes of wrinkles -- in both human skin cells and the sensitive skin of hairless mice following continuing exposure to UV-B, the sun's skin-damaging ultraviolet radioactive rays ... Ellagic acid is an antioxidant found in numerous fruits, vegetables and nuts, especially raspberries, strawberries, cranberries and pomegranates ... the results demonstrate that ellagic acid works to prevent wrinkle formation and photo-aging caused by UV destruction of collagen and inflammatory response"
  • Better skin from the beauty aisle - MSNBC, 1/18/09
  • What Ages Us Most? It's Called Life - Time Magazine, 2/10/09 - "The bottom line is that if you care mostly about a young-looking face, don't smoke, don't go into the sun without protection, and try not to get into a bad relationship that will make you depressed"
  • Three Treatments Shown to Work Against Wrinkles - NYTimes.com, 8/18/08 - "A recent review in The Archives of Dermatology concludes that three anti-aging treatments are proven clinically effective: the topical application of retinol; carbon dioxide laser resurfacing; and injection of hyaluronic acid, a moisture-retaining acid that occurs naturally in the skin" - drugstore.com has retinol.  Also, see hyaluronic acid at iHerb.
  • Study supports lycopene protecting skin from within - Nutra USA, 4/29/08 - "Consuming lycopene-rich tomato paste may protect against sunburn and sun-induced skin ageing ... Skin samples taken from the subjects indicated that the tomato paste-supplemented individuals had higher skin levels of pro-collagen, a molecule which gives the skin its structure and loss of which leads to skin ageing and lack of elasticity" - See Jarrow Lyco-Sorb (contains Lyco-O-Mato) at iHerb.
  • Vitamin C can keep you healthy, looking younger - CNN.com, 2/27/08 - "people who ate foods rich in vitamin C had fewer wrinkles and less age-related dry skin than those whose diets contained only small amounts of the vitamin. C helps form collagen, which smooths fine lines and wrinkles ... Farris recommends La Roche-Posay Active C facial moisturizer or SkinCeuticals C E Ferulic topical antioxidant treatment ... taking more than 700 milligrams of C supplements daily reduced the risk of cardiovascular disease by 25 percent. And a recent study from Harvard University researchers hints that women who take a combo of 500 milligrams of vitamin C daily and 600 IU of vitamin E (another antioxidant) can cut their risk of stroke by 30 percent ... Pairing vitamins C and E is smart for another reason: It may lessen your Alzheimer's risks by as much as 64 percent ..." - See La Roche-Posay Active C facial moisturizer or SkinCeuticals C E Ferulic at Amazon.com and Vitamin C products at iHerb.
  • What To Eat For Glowing Healthy Skin - Science Daily, 11/14/07 - "the antioxidants in vitamins C and E can protect the skin from sun damage and help reduce damage in skin cells caused by harmful free radicals, which contribute to aging skin. Similarly, we have long known that the B vitamin biotin is responsible for forming the basis of skin, hair and nail cells, and vitamin A – found in many fruits and vegetables – maintains and repairs skin tissue"
  • Vitamin K shows potential in the fight against wrinkles - Nutra USA, 10/19/07 - [Abstract] - "Recent studies have linked vitamin K to the elasticity of skin in patients suffering from pseudoxanthoma elasticum (PXE), an inherited condition resulting in severe wrinkling of the skin on the face and body" - See vitamin K products at iHerb.
  • Wrinkle creams: Your guide to younger looking skin - CNN - "Coenzyme Q10 is a nutrient that helps regulate energy production in cells. Some studies have shown reduction in fine wrinkles around the eyes with no side effects"
  • Vitamin C May Slow Skin Wrinkling - WebMD, 10/8/07 - "After adjusting for other factors likely to influence skin aging, such as sun exposure and smoking, vitamin C and linoleic acid were independently associated with skin aging ... After digestion, linoleic acid is converted to DHA and EPA -- two fatty acids" - See vitamin C products at iHerb and Mega Twin EPA at iHerb. - Note:  I'm not sure that is correct.  Linoleic acid is an omega-6, which is not converted to DHA and EPA.  Most Americans get about ten time too much omega-6 already.
  • Dietary nutrient intakes and skin-aging appearance among middle-aged American women - Am J Clin Nutr. 2007 Oct;86(4):1225-1231 - "Higher intakes of vitamin C and linoleic acid and lower intakes of fats and carbohydrates are associated with better skin-aging appearance. Promoting healthy dietary behaviors may have additional benefit for skin appearance in addition to other health outcomes in the population"
  • Antioxidant To Retard Wrinkles Discovered - Science Daily, 8/30/07 - "Antioxidants operate against free radicals which cause a breakdown of many tissues in the body, including the skin. When found in small quantities in the body, free radicals are not harmful and are even involved in various physical processes. When there is an excess of free radicals, however, as occurs during normal aging or as a result of excessive exposure to ultra-violet radiation from the sun, the result, among other things, is a breakdown of the collagen and elastin fibers in the skin. When this happens, there is a loss of skin elasticity and the formation of wrinkles ... A problem with many of the commercial antioxidants found today in the market that are said to retard the aging process is that they oxidize quickly and therefore their efficiency declines with time"
  • Vitamin A (Retinol) Effaces Wrinkles in Naturally Aged Skin - Medscape, 5/39/07 - "Fine wrinkling improved with retinol treatment, whereas there was little change in the control group. This benefit of retinol was evident at 4 weeks of treatment and continued through week 24" - See retinol products at drugstore.comicon.
  • Vitamin A Helps Reduce Wrinkles Associated With Natural Skin Aging - Science Daily, 5/21/07 - "Applying vitamin A to the skin appears to improve the wrinkles associated with natural aging and may help to promote the production of skin-building compounds ... Researchers applied a lotion containing 0.4 percent retinol"
  • On The Cover: Scientifically Advanced Skin Care - Life Extension Magazine, 1/07
  • Lutein skin health study elicits excited response at conference - Nutra USA, 9/13/06 - "the oral lutein supplement was seen to increase skin hydration by 38 per cent, skin elasticity by 8 per cent, and the level of superficial lipids by 33 per cent (after adjustments for placebo)" - See iHerb or Vitacosticon lutein products.
  • Eat Right To Keep Healthy Skin - CBS 2 Chicago, 4/30/05 - "Clinical studies have found that eating a diet rich in fruits, vegetables, whole grains, legumes and omega-3 fatty acids can help skin retain its healthy glow and look youthful ... foods for healthy skin include those rich in lycopene. That's a pigment that gives many fruits and vegetables their red color. It's a proven antioxidant, and antioxidants are important because they reduce the risk of several types of cancer and they prevent the formation of harmful byproducts of metabolism called free radicals"
  • A Partial Reversal of Skin Aging - Life Extension Magazine, 4/04
  • Fighting Back Against Skin Aging - Life Extension Magazine, 8/03
  • Risky Wrinkle Removers? - Dr. Weil, 5/16/03
  • Green Tea Gives Skin Healthy Glow - HealthDay, 5/15/03 - "Green tea contains compounds called polyphenols, which help eliminate free radicals. These free radicals can cause cancer by altering DNA. Polyphenols also protect healthy cells while promoting the death of cancer cells ... Cells that migrate toward the surface of the skin normally live about 28 days, and by day 20 they basically sit on the upper layer of the skin getting ready to die. But EGCG reactivates them ... EGCG may offer potential benefits for skin conditions including psoriasis, rosacea, wrinkles and wounds" - See iHerb or Vitacosticon green tea extracts.  My favorite is Jarrow green tea at iHerb.
  • Vitamin K and niacin good for complexion, experts say - HealthDay, 3/26/03 - "Vitamin K was found to be successful in treating dark circles under the eyes. It's also been found effective for treating bruising on the face following dermatologic procedures such as laser treatment for spider veins ... Niacin shows promise as an over-the-counter ingredient in anti-aging products"
  • Combating Skin Aging - Life Extension Magazine, 1/03 - "Factors that induce skin damage involve the excessive production of free radicals. Protecting against these free radical insults is a proven way to slow the effects of aging ... the vitamin C-treated side of the face showed a statistically significant 71% combined score improvement ... The oral ingestion of fish, flax or perilla oil provides abundant quantities of the omega-3 fatty acids that are so beneficial to the health and appearance of the skin ... DMAE may be the first topical agent that can help firm sagging skin" - See Drugstore.com vitamin C serumsicon and glycolic acidicon products.
  • The Anti-Aging Effects of Carnosine - Life Extension Magazine, 1/03 - "Carnosine quenches the most destructive protein-oxidizing agent (the hydroxyl radical). One study showed carnosine was the only antioxidant to significantly protect cellular chromosomes from oxidative damage.2 Antioxidants cannot completely protect proteins. Nature's second line of defense is to repair or remove damaged proteins.3 This is where carnosine demonstrates its most profound anti-aging effect ... Studies show that carnosine is effective against cross-linking and the formation of advanced glycation end products (AGE).6,7 Glycated proteins produce 50-fold more free radicals than nonglycated proteins and carnosine may be the most effective anti-glycating agent known" - See iHerb and Vitacosticon carnosine products.
  • Preparing Your Own Skin Potions? - Dr. Weil, 7/30/02
  • Few Vitamins Effectively Prevent or Reverse Skin Damage - Medscape, 3/02 - "Despite advertising claims, almost all available topical formulations contain very low concentrations of antioxidants that are not well absorbed by the skin ... There are 3 antioxidants that have been proven to decrease the effect of the sun on the skin and actually prevent further damage: selenium, vitamin E, and vitamin C ... Recent animal studies have found that when selenium is taken orally or through the skin in the form of L-selenomethionine, it provided protection against both everyday and excessive UV damage ... New laboratory studies suggest vitamin E helps inactivate free radicals, making them less likely to cause damage ... Even minimal UV exposure can decrease the vitamin C levels in the skin by 30%, while exposure from the ozone of city pollution can decrease the level by 55%"

General Information:

Other News:

  • New anti-aging treatments make it easier to turn back the clock - Science Daily, 2/7/12 - "The newest filler introduced and approved by the U.S. Food and Drug Administration (FDA) for facial rejuvenation is calcium hydroxylapatite. This filler restores facial volume and promotes collagen production, lasting for up to a year in most cases. This calcium hydroxylapatite filler is thicker than the hyaluronic acid fillers currently available, requiring less product to be used. However, Dr. Kim noted that the thickness of calcium hydroxylapatite also is associated with slightly higher adverse effects than hyaluronic acid fillers ... Dr. Kim recommends that patients look for ingredients such as retinoids (chemical compounds derived from vitamin A), peptides (smaller proteins that stimulate collagen production), and growth factors (compounds that act as chemical messengers between cells and play a role in collagen production). Added into inexpensive skin care products, these have the ability to repair skin damage from sun exposure or other toxic chemicals and, in some cases, stimulate collagen production"
  • FDA Approves Gel Dermal Filler for Facial Wrinkles - Medscape, 11/21/11 - "The product combines a cohesive polydensified matrix technology with a hyaluronic acid base that attracts water to the injected area to fill and plump the wrinkle in natural way ... Potential treatment areas include nasolabial folds, worry lines, crow's feet, lips/chin/cheek augmentation, marionette lines, smile lines, perioral lines, and wrinkles at the décolletage ... According to information on the company Web site, patients are able to see the lines and wrinkles on their face softening and becoming less noticeable immediately after treatment. Results improve during the first week or so and continue for about 6 to 12 months before additional treatments are needed"
  • Facial Wrinkles Linked to Lower Bone Density - WebMD, 6/7/11 - "Researchers measured the number and depth of facial wrinkles and the skin firmness of 114 women who were within three years of their last menstrual period ... Women who had worse wrinkles also had lesser bone density ... Pal thinks the connection may be a protein called type 1 collagen, a building block of skin and bone tissue, which is lost with age. It is thought that this loss may be accelerated during menopause, when hormone levels drop ... The strongest association of the facial wrinkles with the bone was between the eyebrows ... When we looked at the effects of sun exposure on skin, we did not see that women who had more sun exposure had worse skin wrinkles"
  • Nutrition and aging skin: sugar and glycation - Clin Dermatol. 2010 Jul-Aug;28(4):409-11 - "The effect of sugars on aging skin is governed by the simple act of covalently cross-linking two collagen fibers, which renders both of them incapable of easy repair. Glucose and fructose link the amino acids present in the collagen and elastin that support the dermis, producing advanced glycation end products or "AGEs." This process is accelerated in all body tissues when sugar is elevated and is further stimulated by ultraviolet light in the skin. The effect on vascular, renal, retinal, coronary, and cutaneous tissues is being defined, as are methods of reducing the glycation load through careful diet and use of supplements"
  • Phosphorous in sodas and processed foods accelerates signs of aging, study suggests - Science Daily, 4/26/10 - "high levels of phosphates may add more "pop" to sodas and processed foods than once thought. That's because researchers found that the high levels of phosphates accelerate signs of aging. High phosphate levels may also increase the prevalence and severity of age-related complications, such as chronic kidney disease and cardiovascular calcification, and can also induce severe muscle and skin atrophy"
  • Why Women Wrinkle Around Mouth - WebMD, 12/16/09
  • Zap! Wrinkles And Sun Spots Be Gone - Science Daily, 6/1/09 - “Patients are generally treated in two passes. The first pass acts very deeply on the skin, working on deeper lines, atrophic scars and the like,” Orringer says. “The second, more superficial pass, typically focuses more on blending skin tones and getting rid of sun spots and uneven pigmentation.”
  • Face facts: Too much sugar causes wrinkles - MSNBC, 10/21/07 - "At blame is a natural process that's known as glycation, in which the sugar in your bloodstream attaches to proteins to form harmful new molecules called advanced glycation end products (or, appropriately, AGEs for short). The more sugar you eat, the more AGEs you develop. "As AGEs accumulate, they damage adjacent proteins in a domino-like fashion," ... Supplement your diet with at least 1 mg of vitamins B1 and B6 a day. These vitamins proved to be potent AGE inhibitors in a number of published studies"
  • Smokers' Skin Is More Wrinkled, Even In Areas Shielded From Sunlight - Science Daily, 3/22/07
  • Multiple Low-Energy Plasma Skin Treatments May Help Diminish Facial Wrinkles - Doctor's Guide, 2/20/07 - "Three months after treatment, the participants had 37% fewer wrinkles as judged by the researchers, and the patients reported a 68% improvement in overall facial appearance. Tissue had re-grown over the treated area after four days, while patient-reported redness lasted six days. No scarring or loss of pigment occurred. When examining the biopsied skin tissue under a microscope, the researchers found that a new band of collagen, the primary protein in skin, had formed in the inner layers of the skin"
  • Study: Most Wrinkle Creams Don't Work - WebMD, 12/14/06 - "In their first-ever investigation to compare wrinkle creams, Consumer Reports investigators tested nine products, ranging in price from $38 to $335 ... The investigation found only slight improvements overall in wrinkles for any of the tested products"
  • Women's Skin May Age Faster - WebMD, 10/5/06
  • How Long Do Wrinkle Fillers Last? - WebMD, 2/17/06
  • How to Get Younger Looking Hands - ABC News, 10/18/05
  • Fewer Wrinkles And Firmer Skin Linked To Earlier Use Of Estrogen Therapy - Science Daily, 8/26/05 - “We don’t believe hormone therapy will make wrinkles melt away once they’re already there, but the results of our study shows that hormone therapy can prevent them. Hormone therapy makes wrinkles less severe and keeps skin more elastic”
  • Wiping out wrinkles - MSNBC, 2/25/04 - "And in December, the FDA OK'd Restylane, the first drug in a new class of fillers known as hyaluronic acids. Restylane contains a naturally occurring component of skin that serves as a lubricant and shock absorber in joints. It also doesn't require skin testing and the results can last six to nine months or more, twice as long as collagen"
  • New Treatments to Chase Away Wrinkles, Frowns - HealthDay, 9/19/03
  • Wrinkle erasers fill market - USA Today, 5/18/03
  • New Wrinkle Treatment -- Plexiglas [Artecoll] - CBS News, 4/24/03
  • New Treatments for Facial Wrinkles, Acne Scars - HealthDay, 3/12/03
  • New Product [Artecoll] Erases Wrinkles Permanently - The San Diego Channel, 2/26/03
  • New Skin Cream [Avage] Reverses Sun Damage - WebMD, 11/22/02 - "At the 24-week point, researchers found significantly more patients who used the tazarotene cream experienced a more than 50% overall improvement in skin appearance compared to those who received the placebo. The Avage users also reported less wrinkling, mottled pigmentation, and skin roughness" - See See Tazorac at Drugstore.comicon, prescription required.
  • Botulinum Toxin Can Go Systemic for Facial Lines - Doctor's Guide, 9/24/02
  • Palmitoyl Pentapeptide Improves Photo-aged Skin - Doctor's Guide, 7/2/02
  • Premature Skin Wrinkling And Cigarette Smoking In Young People Connected - Doctor's Guide, 3/26/02
  • Signs Of Premature Aging Significantly Improved With Daily Tazarotene Cream - Doctor's Guide, 2/26/02
  • Retinol and Salicylic Acid Combination Facial Cream Improves Both Acne And Photo Aging - Doctor's Guide, 2/24/02 - "developed and tested the efficacy of a new combination facial cream containing stabilized all-trans-retinol 0.075% (vitamin A), salicylic acid 2%, pro-vitamin B5 and anti-oxidants versus placebo ... By the eighth week of treatment, dermatologists noted significant differences between women who used the test cream and placebo controls in coarse wrinkling, laxity of skin, actinic lentigines and skin texture ... Acne products can dehydrate the skin making wrinkles look worse, while some anti-aging products aggravate acne-prone skin ... women are often forced to choose products to treat their more bothersome condition, often at the detriment of the other"
  • Sun Damage to the Skin Can Be Treated - Medscape, 10/00
  • FDA Approves New Formulation Of Renova (Tretinoin Cream) For Reduction Of Fine Facial Wrinkles - Doctor's Guide, 9/6/00

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