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Welcome to the Quality Counts. For those health conscious consumers and medical professionals that are looking to purchase nutritional supplements, vitamins, herbs, learning about medications, losing weight, health food, low carbs, high protein nutrition, and exercise, you have come to the right place. Quality Counts serves both the medical practitioner and consumer interested in nutritional therapy and alternative medicine.
Home > Health Conditions
> Uric Acid
Uric Acid
Alternative News:
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Polyphenols may reduce risk of gout: Study - Nutra USA, 12/13/10 -
"Gout is
a painful form of arthritis caused by disturbances in uric acid metabolism, when
an overload of uric acid leads to the formation of urate crystals in bodily
tissues, especially the joints – leading to recurring attacks of joint
inflammation ... Hyperinsulinemia and insulin resistance can lead to increased
uric acid re-absorption in the kidneys, which in turn can lead to a rise in
serum uric acid concentration ... these results suggest that Oligonol lowers
serum uric acid through inhibition of xanthine oxidase, and may be effective for
prevention and treatment of hyperuricemia and/or gout" - See
oligonol products at iHerb.
-
Vitamin C May Prevent Hyperuricemia, Gout - Medscape, 9/26/08 -
"Hyperuricemia is considered a precursor of gout,
which is the most common inflammatory arthritis in adult men ... An
association was observed between greater vitamin C intake and lower
prevalence of hyperuricemia defined as > 6 mg/dL. The multivariable odds
ratio for hyperuricemia for the highest intake of vitamin C (>1000 mg/d)
compared to the lowest (<90 mg/d) was 0.34 ... These findings support a
potential role of vitamin C in the prevention of hyperuricemia and gout" - See
vitamin C products at iHerb.
Other News:
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Friend or Foe? Uric
Acid a 'Probable Cause' of CVD - Medscape, 4/30/12 -
"Using the electronic database of the HMO, Clalit,
starting in 2002, Leiba et al compared a historical cohort of healthy adults
(40–70 years) with low uric-acid levels (<3 mg/dL) with those who had normal
values (3.1–6.8 mg/dL) during 10 years of follow-up ... After 10 years of
follow-up, healthy subjects with normal uric-acid levels had a 53% higher
risk of developing hypertension (HR 1.53; p<0.001) compared with the
hypouricemic group ... the risks of developing new-onset diabetes and
chronic kidney disease were almost doubled (HR 1.84, p<0.001; and HR 1.93,
p=0.055, respectively) in the normal-uric-acid-level group compared with the
hypouricemic group ... "What do you do about it? I can't imagine putting
people with normal uric acid on allopurinol, so it comes back to the usual
kind of lifestyle advice.""
-
Uric
acid may increase likelihood of severe osteoarthritis - Science Daily,
1/18/11 - "The researchers looked at 159 people, who
had knee osteoarthritis but no history of gout, a type of arthritis
triggered by uric acid crystals in the joints. The researchers found the
severity of osteoarthritis in their knees to be strongly correlated with the
amount of uric acid in their knees. The results, which are published online
in the Proceedings of the National Academy of Sciences, show, despite the
lack of gout history, above normal uric acid levels in 39 percent of the
study population, and evidence of the form of inflammation in the joints
that is typically triggered by uric acid crystals"
-
Uric
acid level and allopurinol use as risk markers of mortality and morbidity in
systolic heart failure - Am Heart J. 2010 Nov;160(5):928-33 -
"The
allopurinol group
and highest uric acid quartile had the highest total mortality (41.7 and
42.4 per 100 person-years, respectively) and combined morbidity/mortality
(45.6 and 51.0 per 100 person-years, respectively). Allopurinol use and
highest uric acid quartile were independently associated with mortality
(hazard ratio [HR] 1.65, 95% CI 1.22-2.23, P = .001 and HR 1.35, 95% CI
1.07-1.72, P = .01, respectively) and combined morbidity/mortality (uric
acid quartile 4 vs 1: HR 1.32, 95% CI 1.06-1.66, P = .02; allopurinol use:
HR 1.48, 95% CI 1.11-1.99, P = .008) ... Elevated uric acid level was
independently associated with mortality in patients with severe systolic HF,
even when accounting for allopurinol use"
-
Serum Uric Acid Linked With Development of Type 2 Diabetes - Science
Daily, 10/2/09 - "The pooled crude relative risk
(RR) of a 1 mg/dL increase in serum uric acid was 1.17"
-
Gout Drug May Lower Blood Pressure - WebMD, 9/23/09 -
"A new study suggests a direct link between a
high-sugar diet and high blood pressure ... allopurinol could lower high
blood pressure by lowering uric acid" - Note: Kind of a
confusing article. Yeah, high blood sugar probably is a cause of high
blood pressure and high uric acid but the article implies that allopurinol
lowers blood pressure by lowering the uric acid not the blood sugar so why
is it discussing blood sugar? I've written WebMD before about
articles like that and they've agreed and changed it. This one is
minor I guess.
-
Healthy People With Elevated Levels Of Uric Acid Are At Risk Of Developing
Kidney Disease - Science Daily, 9/17/08 -
"Elevated uric acid levels in the blood indicate an increased risk of
new-onset kidney disease ... it may be appropriate to prescribe uric
acid–lowering drugs, such as allopurinol and probenecid, to these otherwise
healthy individuals ... individuals in the slightly elevated uric acid group
were 1.26 times as likely to develop kidney disease as those in the low uric
acid group. The odds of developing kidney disease among volunteers in the
elevated uric acid group were 1.63 times greater than that of individuals in
the low uric acid group"
-
High
Levels Of Uric Acid May Be Associated With High Blood Pressure - Science
Daily, 8/26/08 - "In the study, half of the 30
teen-agers with newly diagnosed high blood pressure and higher than normal
levels of uric acid in their blood underwent treatment with allopurinol
twice a day for four weeks. The other half received a placebo (an inactive
drug) on the same schedule. They then went without either drug for two weeks
before receiving the opposite treatment for another four weeks ... blood
pressures decreased to normal in 20 of the 30 teens when they were on
allopurinol. By contrast, only 1 of the 30 teens had normal blood pressure
when receiving placebo"
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