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Anti-aging Research > Trans Fatty Acids
Trans Fatty Acids
News & Research:
Trans Fats From Foods May Worsen Memory, Study Finds - WebMD, 6/17/15 -
"each gram of trans fats eaten per day was
associated with 12 to 21 fewer words recalled, out of an average score of 86
... Golomb calls trans fats an "anti-food," noting that they increase levels
of "bad" LDL cholesterol while simultaneously driving down levels of "good"
HDL cholesterol ... Trans fats also increase inflammation and interfere with
hormone production ... Besides causing inflammation, trans fats might also
inhibit the body's production of omega 3 fatty acids"
Trans fat consumption linked to diminished memory in working-aged adults
- Science Daily, 11/18/14 - "From a health
standpoint, trans fat consumption has been linked to higher body weight,
more aggression and heart disease ... Among men under age 45, those who ate
more trans fats showed notably worse performance on the word memory test ...
Each additional gram a day of trans fats consumed was associated with an
estimated 0.76 fewer words correctly recalled"
trans fat consumption linked to greater aggression, researchers find -
Science Daily, 3/13/12 - "The study of nearly 1,000
men and women provides the first evidence linking dTFAs with adverse
behaviors that impacted others, ranging from impatience to overt aggression
... We found that greater trans fatty acids were significantly associated
with greater aggression, and were more consistently predictive of aggression
and irritability, across the measures tested, than the other known
aggression predictors that were assessed"
Alzheimer's: Diet patterns may keep brain from shrinking - Science
Daily, 12/29/11 - "People with diets high in several
vitamins or in omega 3 fatty acids are less likely to have the brain
shrinkage associated with Alzheimer's disease than people whose diets are
not high in those nutrients ... Those with diets high in omega 3 fatty acids
and in vitamins C, D, E and the B vitamins also had higher scores on mental
thinking tests than people with diets low in those nutrients ... people with
diets high in trans fats were more likely to have brain shrinkage and lower
scores on the thinking and memory tests than people with diets low in trans
fats" - See
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Eating poorly can make you blue: Trans-fats increase risk of depression,
while olive oil helps avoid risk - Science Daily, 1/26/11 -
"the participants with an elevated consumption of
trans-fats (fats present in artificial form in industrially-produced
pastries and fast food, and naturally present in certain whole milk
products) "presented up to a 48% increase in the risk of depression when
they were compared to participants who did not consume these fats," ... In
addition, the study demonstrated a dose-response relationship, "whereby the
more trans-fats were consumed, the greater the harmful effect they produced
in the volunteers," ...Furthermore, the team, ... also analyzed the
influence of polyunsaturated fats (abundant in fish and vegetable oils) and
of olive oil on the occurrence of depression. "In fact, we discovered that
this type of healthier fats, together with olive oil, are associated with a
lower risk of suffering depression,""
fructose, trans fats lead to significant liver disease, says study -
Science Daily, 6/22/10 - "mice fed the normal
calorie chow diet remained lean and did not have fatty liver disease. Mice
fed high calorie diets (trans-fat alone or a combination of trans-fat and
high fructose) became obese and had fatty liver disease ... it was only the
group fed the combination of trans-fat and high fructose which developed the
advanced fatty liver disease which had fibrosis ... This same group also had
increased oxidative stress in the liver, increased inflammatory cells, and
increased levels of plasma oxidative stress markers"
Eating Fish, Nuts And Olive Oil May Be Associated With Reduced Risk Of
Age-related Blindness - Science Daily, 5/15/09 -
"Individuals who consumed higher levels of trans-unsaturated fats—found in
baked goods and processed foods—were more likely to have late AMD, whereas
those who consumed the most omega-three fatty acids were less likely to have
early AMD. "Olive oil intake (100 milliliters or more per week vs. less than
1 milliliter per week) was associated with decreased prevalence of late
AMD," the authors write. "No significant associations with AMD were observed
for intakes of fish, total fat, butter or margarine.""
Oil Not A Healthy Substitute For Trans Fats, Study Finds - Science
Natural Oils Can Be Hydrogenated Without Making Unhealthy Trans Fats -
Science Daily, 1/23/09
Not All Trans Fats Are Equally Risky - WebMD, 3/7/08
Are trans fat substitutes really healthier? - CNN, 4/16/07
Trans Fats, Heart Risk: 'Strong' Link - WebMD, 3/26/07
Nutrition Researchers Provide The Skinny On Trans Fats - Science Daily,
McDonald's finally settles on trans-fat-free cooking oil - USA Today,
Trans Fats May
Increase Infertility - WebMD, 1/12/07
Trans Fats Up
Heart Disease Risk - WebMD, 11/15/06 -
"even those eating just 1.3 grams per 1,000 calories
per day were at increased risk ... That's not much, when you consider that a
typical serving of french fries has about 5 grams of trans fats, a Danish
has more than 3 grams, and even microwave popcorn has 1.1 grams"
Trans fat adds more pounds than other fat, research indicates - USA
Trans Fat Leads To Weight Gain Even On Same Total Calories, Animal Study
Shows - Science Daily, 6/19/06 - "Diets rich in
trans fat cause a redistribution of fat tissue into the abdomen and lead to
a higher body weight even when the total dietary calories are controlled"
Eat Trans Fat, Get
Big Belly - WebMD, 6/12/06 - "Trans fats make
you fatter than other foods with the same number of calories -- but that's
not all ... trans fats increase the amount of fat around the belly"
How Much Trans Fat
in Those Fries? - WebMD, 4/12/06
- How to keep trans fats
under control - MSNBC, 2/10/06 -
"But the Daily Value for saturated fat is high for
two reasons. It overestimates the amount needed by people who should have
less than 1,800 calories per day because they are sedentary or overweight.
It also overestimates how much the average person with high blood
cholesterol should have. Their saturated fat should be below seven percent
of their calorie total"
Trans Fats May Raise Risk of Gallstones - WebMD, 5/11/05 -
"those who consumed the most trans fats had a 23%
higher risk of gallstone disease than those who ate the least amount of
- Trans fat-free — the next
food fad? - MSNBC, 1/18/05
What’s Wrong with Trans Fats? - Delicious Living, 1/05
- Group Wants
Trans Fats Banned - WebMD, 5/18/04
- Trans Fat
Raises Bad Cholesterol - WebMD, 4/19/04
- Dietary Trans Fatty
Acids Increase Small, Dense LDL Particles - Medscape, 9/2/03 -
"Consumption of dietary trans fatty acids (FAs) is
associated with a deleterious increase in small, dense low-density
lipoprotein (LDL) cholesterol particles ... Accumulating evidence indicates
that the size of LDL particles confers an independent risk, with small and
dense particles being more atherogenic than are larger, less dense particles
... the diet enriched with saturated fat (butter) was associated with the
highest plasma LDL-cholesterol concentrations but, paradoxically, the
largest LDL particles ... These data reinforce the importance of promoting
diets that are low in saturated fat and that contain a minimal quantity of
trans fatty acids"
- Targeting Trans Fatty
Acids? - Dr. Weil, 7/29/03
Fessing Up to Fats - Time Magazine, 7/21/03 -
"Even small quantities of trans-fatty acids, we now
know, raise bad cholesterol and other blood fats. They may also reduce
levels of HDL — or good — cholesterol and increase the risk of diabetes. And
because of antiquated labeling rules, products that were practically
swimming in trans-fatty acids could be called "fat-free.""
- Trans Fatty
Acids - WebMD, 7/11/03 -
"Saturated fats and trans fat have bad effects on
cholesterol levels. Polyunsaturated fats and monounsaturated fats (such as
olive oil, canola oil, soybean oil, and corn oil) have good effects ... If
the ingredient list includes the words "shortening," "partially hydrogenated
vegetable oil" or "hydrogenated vegetable oil," the food contains trans fat.
Because ingredients are listed in descending order of predominance, smaller
amounts are present when the ingredient is close to the end of the list"
- Food Labels to
Include Trans Fat Content - WebMD, 7/9/03
- Is Butter Better? - Dr.
Weil, 2/28/03 -
"margarine is made from liquid vegetable oils that
are artificially saturated (with hydrogen) to make them semisolid. This
process changes the fat molecules making them capable of damaging arteries
and raising the risk for heart attack. I believe that these oils also
promote cancer, inflammation, damage to the immune system and premature
aging. Some of this harm is due to unnatural fat molecules (trans-fats)
created in the hydrogenation process."
- Unhealthy Trans
Fats Not Labeled on Foods - WebMD, 2/10/03 -
"[Trans fats] are there and they are not labeled ...
Saturated fats are the only fats given special treatment on a product's
label. Yet trans fats are just as bad. They may even be worse ... Trans fat
increases 'bad' LDL cholesterol -- in some studies more than saturated fat
... It also has a tendency to reduce 'good' HDL
cholesterol, which saturated fat doesn't do ... Trans fat also increases
blood levels of two other bad actors. One is the kind of fat called
triglycerides. The other is a particle called lipoprotein(a), which
promotes clogged arteries ... Any amount of trans fat is bad"
- New Report Says Only
Safe Intake of Trans Fatty Acids is Zero - New Hope Natural Media,
"Studies show that these fats elevate total
cholesterol levels, decrease
high-density lipoprotein (“good”) cholesterol, and interfere with
essential fatty acids and with the liver’s detoxification system. There is
circumstantial evidence that consuming trans fatty acids may increase the
risk of developing heart disease or
- Is New Improved [Smart
Balance] Margarine Good for You? - Dr. Weil, 4/3/02 -
"While Smart Balance may be better than most
margarine – if you adhere to the specified "balance" of fats in the rest of
your diet – my views about margarine remain unchanged. It is still fat,
mostly unhealthy fat, and a highly processed food. The less processed food
you eat, the better."
Trans-Fatty Acids In Diet May Be Associated With First Heart Attack -
Doctor's Guide, 2/20/02
Hydrogenated Oils Affect Amount of Vitamin K Available to Bone -
Doctor's Guide, 11/30/01 -
"Hydrogenation of plant oils decreases the amount of
vitamin K available to bone in consumers using food products containing the
oils ... available data indicate that more than half of younger US adults do
not meet the current guidelines governing adequate intake of the nutrient"
- Another reason to stay away from the brands of peanut butter that are
hydrogenated. - Ben
- Trans Fats and Type
II Diabetes - DrMirkin.com, 11/15/01 -
"Until labeling laws are changed, the only way to
know whether a food contains trans fats is to read the list of ingredients
on any processed food. If you see the words "partially hydrogenated" in
front of any vegetable oil, the food contains trans fats"
- Trans Fats
Tops List of Heart Unhealthy Foods - WebMD, 7/13/01 -
"That treat you love probably contains trans fats,
which not only affect your cholesterol levels, but also may harm the
functioning of your blood vessels. This dangerous combination may increase
atherosclerosis, the hardening of your arteries ... A diet high in trans
fats appears to be unhealthier than a diet that's "just high in saturated
- 'Bad' Fats
Found in Processed Foods Linked to Diabetes Risk - WebMD, 6/8/01 -
"Fats known as trans fatty acids, commonly seen in
these foods, already have been linked to heart disease and high cholesterol.
Now a study from the Harvard School of Public Health suggests that limiting
their consumption also can greatly lower diabetes risk"
High Trans Fatty Acid Intake Linked To Coronary Heart Disease - Doctor's
- Trans Fatty
Acids Enough of a Risk for the FDA to Consider New Labeling Laws -
WebMD, 3/8/01 -
"Increasingly, scientific evidence is demonstrating
that eating foods containing trans fatty acids contributes to increases in
LDL or "bad" cholesterol and decreases in HDL or "good" cholesterol. They
also may have other negative effects on heart health. This is a major
concern in North America, where intake of trans fatty acids, which are found
not only in margarines but also in many baked goods as well as processed and
fast foods, is high and where heart disease is the leading cause of death .
. . a 2% increase in trans fatty acid intake causes a 25% jump in the risk
of heart disease . . . you are not doing yourself any favors by substituting
trans fatty acids for saturated fats" - I feel that the producers of
these new "stanol" margarines are pulling a wall
over customer's head because their products contain trans fatty acids. See
"partially hydrogenated soybean oil" on their ingredients list. - Ben
- All Fats Are
Not Created Equal, Trans Fats, Omega Fats, Good Fats, Bad Fats: Are You
Confused? - WebMD, 7/4/00 -
"Trans fats act very much like saturated fat in
raising cholesterol levels. They also lower good HDL cholesterol, the
protective cholesterol. ... Some people say they're actually worse than
Compared to Low Dietary Intake of trans-Fatty Acids Impairs Strength of Old and
Aerobic Capacity of Young SAMP8 Mice in Both Sexes - Lipids. 2013 Aug 18 -
"We studied the effects of trans-fatty acids (2 % of
total energy, TFA diet) on the loss of strength and aerobic exercise capacity
(VO2peak) with age. SAMP8 mice were studied at two ages (young, 25 weeks; old,
60 weeks) and on two diets (control vs TFA) ... There was a significant
age-related decline in total grip strength as well as that normalized to
fat-free mass (FFM) (p < 0.05) with a further decrease at old age in these
metrics of strength on the TFA diet vs control diet"
trans Fatty Acid Intake Is Associated with Increased Risk and n3 Fatty Acid
Intake with Reduced Risk of Non-Hodgkin Lymphoma - J Nutr. 2013 Mar 13 -
"diets high in TFAs, processed meats, and higher fat
dairy products were positively associated with NHL risk, whereas diets high
in n3 fatty acids and total seafood were inversely associated with risk"
Nutrients and risk of prostate cancer - Nutr Cancer. 2010
Aug;62(6):710-8 - "Intake of trans fat was
associated with the risk of PCa; the OR for the highest vs. the lowest
quartile was 1.45 (95% CI = 1.16-1.81); the association was apparently
stronger in subjects aged less than 65, normal weight men, and ever smokers.
An increased risk was also observed with increasing intake of sucrose and
disaccharides. In contrast, men in the highest quartile of cholesterol
intake were at lower risk of PCa. No association was found with intake of
total proteins, total fat, monounsaturated fats, polyunsaturated fats,
monosaccharides, and total carbohydrates. The findings provide evidence that
a diet low in trans fat could reduce PCa risk"
consumption and its association with age-related macular degeneration -
Arch Ophthalmol. 2009 May;127(5):674-80 - "Higher
trans-unsaturated fat intake was associated with an increased prevalence of
late AMD; the odds ratio comparing the highest with the lowest quartile of
trans fat was 1.76 (95% confidence interval, 0.92-3.37; P = .02). Higher
omega-3 fatty acid intake (highest quartile vs lowest quartile) was
inversely associated with early AMD (odds ratio, 0.85; 95% confidence
interval, 0.71-1.02; P = .03). Olive oil intake (> or =100 mL/week vs <1
mL/week) was associated with decreased prevalence of late AMD (odds ratio,
0.48; 95% confidence interval, 0.22-1.04; P = .03). No significant
associations with AMD were observed for intakes of fish, total fat, butter,
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fatty acids and trans fatty acids in patients with the metabolic syndrome: a
case-control study in Korea - Br J Nutr. 2008 Feb 28;:1-6 -
"trans fatty acids of erythrocytes (RBC) ... There
were significant positive relationships between trans fatty acids and waist
circumference, and between trans fatty acids and BMI. The results suggested
that RBC trans fatty acids might be a predictor of increased risk for the
metabolic syndrome, but n-3 fatty acids were not in this population"
A prospective study of trans-Fatty Acid levels in blood and risk of prostate
cancer - Cancer Epidemiol Biomarkers Prev. 2008 Jan;17(1):95-101 -
"The relative risks (95% confidence intervals; P
trend) comparing top with bottom quintile trans-fatty acid levels were 2.16
(1.12-4.17; 0.11) for 18:1n-9t, 1.97 (1.03-3.75; 0.01) for total 18:2t, and
2.21 (1.14-4.29; 0.06) for total trans-fatty acids"
Dietary Fats and the Risk of Incident Alzheimer Disease - Archives of
Neurology, 2/03 -
"Intakes of saturated fat and trans-unsaturated fat
were positively associated with risk of
whereas intakes of
polyunsaturated fat and monounsaturated
fat were inversely associated. Persons in the upper fifth of saturated-fat
intake had 2.2 times the risk of incident Alzheimer disease compared with
persons in the lowest fifth" - See the tables on my
fatty acids page. For example, palm oil is 51% saturated fat while
canola oil is 8% saturated.
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