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Home > Health Conditions > Stress

Stress

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  • Does depression contribute to the aging process? - Science Daily, 2/21/12 - "telomere length was shorter in the depressed patients, which confirmed prior findings. Importantly, they also discovered that shorter telomere length was associated with a low cortisol state in both the depressed and healthy groups ... stress plays an important role in depression, as telomere length was especially shortened in patients exhibiting an overly sensitive HPA axis. This HPA axis response is something which has been linked to chronic stress and with poor ability to cope with stress" - Note:  I'm not sure if that's correct because depressed people usually have high cortisol, not low cortisol.  I read somewhere that PTSD was associated with low cortisol.
  • Anticipation of stressful situations accelerates cellular aging - Science Daily, 2/21/12 - "The researchers assessed cellular age by measuring telomeres, which are the protective caps on the ends of chromosomes. Short telomeres index older cellular age and are associated with increased risk for a host of chronic diseases of aging, including cancer, heart disease and stroke ... higher levels of anticipated threat in daily life may promote cellular aging in chronically stressed individuals"
  • Depression and chronic stress accelerates aging - Science Daily, 11/9/11 - "The telomere is the outermost part of the chromosome. With increasing age, telomeres shorten, and studies have shown that oxidative stress and inflammation accelerates this shortening. On this basis it has been suggested that telomere length is a measure of biological aging, and telomere length has subsequently been linked to age-related diseases, unhealthy lifestyle, and longevity. The research team shows that shorter telomere length is associated with both recurrent depression and cortisol levels indicative of exposure to chronic stress"
  • At last, a reason why stress causes DNA damage - Science Daily, 8/21/11
  • Stress can affect future offspring - Science Daily, 8/16/11
  • Stress may increase risk for Alzheimer's disease - Science Daily, 5/26/11 - "Fewer than ten percent of Alzheimer cases have a genetic basis. The factors that contribute to the rest of the cases are largely unknown ... life events (stress) may be one trigger ... stress, and the hormones released during stress, can accelerate the development of Alzheimer disease-like biochemical and behavioural pathology"
  • Social isolation, stress-induced obesity increases breast cancer risk in mice - Science Daily, 4/4/11 - "Stress from social isolation, combined with a high-fat diet, increases levels of a brain neurotransmitter -- neuropeptide Y, or NPY -- in mice that then promotes obesity, insulin resistance, and breast cancer risk ... To conduct the study, the researchers used female mice that develop breast cancer when given progesterone and a carcinogen. They established four groups of these mice: one group that lived together (not socially isolated) and ate a normal diet; a group that was isolated (each alone in a cage) and ate normally; an isolated group that ate a high-fat diet, and a group that lived together and ate a high-fat diet ... Ten weeks after treatment and living in these environments (for a total of 17 weeks), 92 percent of the socially-isolated mice fed a high-fat diet had developed tumors, compared to 36 percent of socially-isolated mice fed a normal diet and 36 percent of grouped mice that were also fed normally. But 67 percent of mice who were happy in group homes, but were fed a high fat diet, developed breast cancer"
  • Even mild stress is linked to long-term disability, study finds - Science Daily, 3/23/11 - "Between 2002 and 2007, the authors tracked the health of more than 17,000 working adults up to the age of 64, who had been randomly selected from the population in the Stockholm area ... Higher levels of stress at the start of the study were associated with a significantly greater likelihood of subsequently being awarded long term disability benefits ... But even those with mild stress were up to 70% more likely to receive disability benefits ... One in four of these benefits awarded for a physical illness, such as high blood pressure, angina, and stroke, and almost two thirds awarded for a mental illness, were attributable to stress"
  • Simple spit and blood tests might detect burnout before it happens - Science Daily, 2/21/11 - "In addition to professional and personal suffering, burnout puts distressed workers at further risk of physical and psychological problems if ignored ... We hypothesized that healthy workers with chronic stress and with mild burnout symptoms would have worse physiological dysregulations and lower cortisol levels -- a profile consistent with burnout ... Cortisol is a stress hormone involved in our bodies stress response and naturally as part of our body's daily rhythm. Cortisol levels are often high in people suffering from depression, while it tends to be low in cases of burnout. Too much cortisol can be as bad as too little when it comes to both mental and physical health ... Critically, people with burnout are often treated with anti-depressant medications that lower cortisol levels. If cortisol is already lower than it should be, this course of treatment could represent a therapeutic mistake. "The use of an allostatic load index gives researchers and clinicians a window to see how chronic stress is straining the person"
  • Casualties of war: Wounded veterans more likely to die of coronary heart disease - Science Daily, 1/26/11 - "During the 28 year follow up , out of 412 deaths, 140 were due to coronary heart disease (CHD), making wounded veterans 1.7 times more likely to die from CHD than the comparison group ... those who had been wounded in action had a higher BMI, a greater history of self-reported depression and were more likely to be claiming disability pension. This also suggests that as well as increased risk of PTSD, physical trauma in early life may cause longstanding physiological implications"
  • Social stress leads to atherosclerosis, research suggests - Science Daily, 12/6/10
  • Stress accelerates breast cancer progression in mice, researchers find - Science Daily, 9/15/10 - "stress is biologically reprogramming the immune cells that are trying to fight the cancer, transforming them instead from soldiers protecting the body against disease into aiders and abettors. The study found a 30-fold increase in cancer spread throughout the bodies of stressed mice compared to those that were not stressed ... Beta blockers, used in this study to shut down the stress pathways in the mice, are currently being examined in several large breast cancer databases for their role in potential prevention of recurrence and cancer spread ... using beta blockers in stressed mice prevented the same cancer progression seen in the stressed mice that did not receive medication"
  • Hair provides proof of the link between chronic stress and heart attack - Science Daily, 9/3/10 - "Cortisol is considered to be a stress hormone. Its secretion is increased during times of stress. Traditionally it's been measured in serum, urine and saliva, but that only shows stress at the time of measurement, not over longer periods of time. Cortisol is also captured in the hair shaft"
  • Seeing family for the holidays? Scientists discover how the stress might kill you - Science Daily, 11/30/09
  • Prolonged Stress Sparks Endoplasmic Reticulum To Release Calcium Stores And Induce Cell Death In Aging-related Diseases - Science Daily, 9/27/09
  • Stress Raises Belly Fat, Heart Risks - WebMD, 8/6/09 - "Even compared to other monkeys with the same body mass index and weight, CT scans showed that the stressed monkeys had a great deal more belly fat. And when the researchers looked at the animals' arteries, they found plaque clogging the arteries of the stressed monkeys ... it's not how much fat you have, but where it is located ... Over time, high cortisol levels cause belly fat to accumulate. It also makes individual fat cells get larger ... When you have lots more fat in visceral fat cells and all the characteristics of the metabolic syndrome, each of these things promotes atherosclerosis"
  • Life's Stress May Lead to Weight Gain - WebMD, 7/8/09
  • Stress Makes Your Hair Go Gray - Science Daily, 6/11/09 - "Those pesky graying hairs that tend to crop up with age really are signs of stress, reveals a new report in the journal Cell"
  • Symptoms Of Depression Associated With Increase In Abdominal Fat - Science Daily, 12/1/08 - "There are several mechanisms by which depression might increase abdominal fat, they note. Chronic stress and depression may activate certain brain areas and lead to increased levels of the hormone cortisol, which promotes the accumulation of visceral fat. Individuals with depression may have unhealthier lifestyles, including a poor diet, that could interact with other physiological factors to produce an increase in abdominal obesity" - See my cortisol page for ways to reduce it.  Cortisol is like the chicken and the egg with depression.  They don't seem to know whether it is the cause or result.
  • Psychological Distress May Increase Risk of Breast Cancer - Medscape, 9/15/08 - "The team evaluated interactions between breast cancer and severe life events -- such as loss of a parent or divorce of parents before age 20, or loss of a close relative or spouse -- and mild to moderate life events -- e.g., separation from a spouse, loss of a job, an economic crisis, or severe illness in a close relative ... Multivariate analysis revealed a positive association (odds ratio, 1.62) between exposure to more than one adverse life event and breast cancer. "It wasn't enough to be exposed to one life event, a woman had to be exposed to more than one event,""
  • Neurogenesis In Adult Brain: Association With Stress And Depression - Science Daily, 8/31/08 - "Chronic stress can affect the brain and lead into depression"
  • Stress Hormone Found To Regulate Brain Neurotransmission - Science Daily, 8/7/08 - "When we are subjected to a stress, our adrenal glands secrete hormones that affect our entire body. One of these hormones, cortisol, enables us to adapt physically and mentally to the stimulus. Following a major or repeated stress that the individual has no control over, however, cortisol is secreted in great quantities over a long period of time. This hypersecretion has damaging effects on the individual, to the point of accelerating aging and facilitating the onset of illnesses such as depression"
  • Stress May Increase A Woman's Risk Of Developing Cervical Cancer - Science Daily, 2/15/08
  • Stress At Work Is Linked To Heart Disease - Science Daily, 1/22/08 - "chronic work stress was associated with CHD and this association was stronger among both men and women aged under 50 -- their risk of CHD was an average of 68% more than for people who reported no stress at work"
  • Sept. 11 Stress Increases Risk Of Heart Problems, Study Suggests - Science Daily, 1/7/08 - "Our study is the first to show that even among people who had no personal connection to the victims, those who reported high levels of post-traumatic stress symptoms in the days following the 9/11 attacks were more than twice as likely to report being diagnosed by their doctors with cardiovascular ailments like high blood pressure, heart problems and stroke up to three years later"
  • Depression Associated With Low Bone Mineral Density - Medscape, 12/3/07 - "The novelty of this study is the fact that these women were not severely depressed ... Depression is considered a disease of chronic stress, Dr. Cizza said, with attendant increases in the stress hormone cortisol, and cytokines produced by the immune system. "Those substances are helpful to fight stress, but if there is too much cortisol or cytokines, there are side effects," he said. "One of the side effects is bone loss, so it was obvious to ask the question, 'do women with depression have low bone mass?'""
  • Stress Hormone May Hasten The Progression Of Certain Blood Cancers - Science Daily, 11/19/07
  • Feeling Stressed? How Your Skin, Hair And Nails Can Show It - Science Daily, 11/12/07 - "When a person becomes stressed, the level of the body’s stress hormone (cortisol) rises. This in turn causes an increase in oil production, which can lead to oily skin, acne and other related skin problems ... stress has a negative effect on the barrier function of the skin, resulting in water loss that inhibits the skin’s ability to repair itself after an injury"
  • Psychological Stress May Mar Skin WebMD, 11/1/07
  • How Stress Harms the Heart - Time, 10/9/07
  • Stress Contributes To Range Of Chronic Diseases, Review Shows - Science Daily, 10/9/07
  • High Hostility Linked with Poor Ability to Cope With Stress, Low HDL Levels - Medscape, 8/30/07 - "individuals who were very hostile were more likely to perceive problems as stressful and to cope with stress by using interpersonal hostility, self-blame, and social isolation; they also tended to have lower levels of HDL"
  • New Alzheimer's findings: High stress and genetic risk factor lead to increased memory decline - Doctor's Guide, 8/27/07 - "High stress levels may contribute to memory loss among people at risk for developing Alzheimer's disease"
  • Coping With Stress Helps Cholesterol - WebMD, 8/20/07 - "People who coped well had higher levels of HDL than people who didn't cope well ... The amount of stress you deal with isn't as important, they also found, as how you deal with it. "Stress doesn't matter nearly as much as how you cope with it,""
  • Stress May Wreak Havoc on Your Mouth - WebMD, 8/13/07
  • Job Stress Jacks Up Blood Pressure - WebMD, 4/10/07 - "Their blood pressure was highest on the job, when they had 5.9/3.0 mm Hg higher blood pressure than the nonstressed workers did. But the stressed-out workers also had higher blood pressure while at home, including while they were sleeping"
  • Stress May Help Cancer Cells Stay Alive - Doctor's Guide, 4/10/07 - "the stress hormone epinephrine causes changes in prostate and breast cancer cells that may make them resistant to cell death"
  • Reactions to Stress May Affect Brain Aging - Medscape, 8/14/06 - "the adrenal stress hormone cortisol appears to play an important role in mediating the effects of stress on the brain ... Although acute stress seems to enhance immune function and improve memory, chronic stress has the opposite effect and may even lead to disorders that become more prevalent with aging, such as depression, diabetes, and cognitive impairment"
  • Chronic Stress May Make You Age Faster - WebMD, 8/11/06 - "Chronic stress -- the type that drags on, rather than being just a momentary crisis -- can affect hormone levels and shift the body's delicate hormone balance ... In this way, there may be synergistic effects of aging and chronic stress"
  • Chronic Stress, Depression and Cortisol Levels Are Potential Risk Indicators for Periodontal Disease - Doctor's Guide, 5/31/06 - "being a caregiver to relatives with dementia, hypercortisolemia (overproduction of cortisol) or stress were associated with elevated plaque levels and increased gingival bleeding in a study that examined adults aged 50 years and older"
  • Stress at Work an Important Risk Factor for Development of Heart Disease and Diabetes - Doctor's Guide, 1/20/06 - "Researchers examined the association between work stress and the metabolic syndrome ... men with chronic work stress were nearly twice as likely to develop the syndrome than those with no exposure to work stress"
  • Sweet Snacks Could Be Best Medicine For Stress - Science Daily, 11/28/05
  • Cut Stress, Help Your Cholesterol - WebMD, 11/22/05
  • Drug Counters Mental Effect of Stress - WebMD, 11/16/05
  • Women More Sensitive to Stress Than Men? - WebMD, 11/15/05
  • Lost Extra Weight? Stress May Help Gain It Back - WebMD, 10/17/05
  • Chronic Stress Makes Cells Age Faster - WebMD, 11/29/04 - "In translating telomere length into years of aging, researchers determined the cells from the highly stressed mothers had aged from nine to 17 additional years compared with the cells from the low-stress mothers"
  • Stress Linked to Painful Menstrual Periods - WebMD, 11/17/04
  • Commuting Stress Hurts Heart - WebMD, 9/21/04
  • Levels Of Certain Hormones May Be Increased By Stress - Science Daily, 8/3/04
  • Women Snack More After Stress - WebMD, 5/28/04
  • Stress Disrupts Sleep in More Ways Than One - WebMD, 2/6/04
  • In times like these, depressive disorders are a danger - USA Today, 10/6/03
  • Stress Feeds the Need for Comfort Food - WebMD, 9/9/03
  • Job Worries Up Women's Heart Attack Risk - WebMD, 9/4/03 - "Many studies have pointed to high blood pressure, insomnia, anxiety, and depression -- as well as increased levels of the stress hormone cortisol"
  • Is all that stress killing you? - USAToday.com, 5/26/03
  • Highly Educated Workers More Stressed - WebMD, 4/18/03
  • New Stress-Buster Drugs Block Hormone Binding - Clinical Psychiatry News, 4/03 - "A new class of anxiety-relieving drugs—agents that interrupt core hypothalamic-pituitary-adrenal (HPA) stress signals—will emerge in the next 2-3 years ... In his HPA axis model of depression, the affected individual has a blunted ability to counterregulate in response to stress-induced cortisol increases, and thus is unable to turn off the fight-or-flight HPA mechanism. The result is constant anxiety and overreaction to external stimuli, followed by a sense of learned helplessness and loss of motivation. Many symptoms of deeply entrenched depression—anxiety, loss of appetite, reduced libido, elevated heart rate, hypertension, and dyslipidemia—point to HPA dysregulation ... People with melancholic depression do tend to produce abnormally high levels of CRH. These individuals also have elevated levels of cortisol" - See my cortisol page for ways to reduce it.
  • High stress before cancer diagnosis may raise risk - USA Today, 3/10/03
  • Can Stress Affect Your Overall Health? - TheSanDiegoChannel.com, 2/20/03
  • Chronic Stress And Metabolic Syndrome Linked - Doctor's Guide, 11/27/02 - "While the 24-hour cortisol metabolite and normetanephrine (three-methoxynorepinephrine) outputs were higher among cases than controls, HRV and total power were lower among cases" - Makes sense.  Stress increases cortisol, cortisol causes high blood sugar.  Also see my metabolic syndrome page. - Ben
  • Too Much Stress Hinders Immune System - WebMD, 11/4/02
  • Job Stress, Work Strain Double Risk of Death From Heart Disease - WebMD, 10/17/02
  • Financial Stress of Job Loss Linked to Poor Health - WebMD, 10/8/02
  • Exercise, Eating to Enhance Memory? - Dr. Weil, 9/26/02 - "Dr. Khalsa explains that in addition to age, chronic stress can harm the hippocampus via the release of high levels of the hormone cortisol from the adrenal gland"
  • Stress Affects Men's Health More - WebMD, 9/25/02
  • Taking Action Best for 9/11 Stress - WebMD, 9/10/02
  • Putting the Reins on Stress - WebMD, 9/5/02
  • Practical Stress Management Program Found To Improve Health Of People With Type 2 Diabetes - Doctor's Guide, 8/26/02
  • Mental Stress, Physical Illness - WebMD, 8/12/02 - "women who report high levels of mental stress are twice as likely to die from stroke or heart disease than those with low stress levels. And stressed-out men may not fare much better" - This article doesn't get in to it but stress raises cortisol, which may be responsible for the damage.
  • Putting the Reins on Stress - WebMD, 10/10/01

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