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Home > Anti-aging Research > Spirulina

Spirulina

Specific Recommendations:

News & Research:

  • Spirulina (Aphanizomenon flos-aquae) - M. D. Anderson Cancer Center
  • Spirulina shows immune boosting power for seniors - Nutra USA, 2/17/11 - "Twelve weeks of spirulina supplementation were associated with increased counts of white blood cells, foot soldiers of the immune system ... Immune function was measured using complete blood cell (CBC) counts and indoleamine 2,3-dioxygenase (IDO) enzyme activity, and results showed that over half of all participants receiving spirulina had higher IDO activity after 6 and 12 weeks, while this proportion was “striking in men with over 75 percent of subjects manifesting such phenomenon” ... In terms of cell counts, spirulina was associated with a steady increase in corpuscular hemoglobin, thereby ameliorating anemia" - [Abstract]
  • Spirulina extract may reverse pain sensitivity - Nutra USA, 6/2/09 - "Both doses of C-phycocyanin were found to “significantly attenuate carrageenan-induced” inflammation ... Markers of inflammation, including inducible nitric oxide synthase (iNOS), cyclooxygeanase-2 (COX-2), and the formation of nitrate, tumour necrosis factor-alpha (TNF-alpha) and prostaglandin E2, were also measured ... induction of both iNOS and COX-2 was suppressed by the compound, and this was accompanied by an inhibition of the nitrate, PGE, and TNF-alpha formation" - [Abstract] - See spirulina products at iHerb.
  • Want Antioxidants? Have You Eaten Micro-algae Lately? - Science Daily, 10/11/07
  • In Praise of Spirulina - CancerDecisions.com, 12/12/02 - "According to a recent scientific review from Latin America, spirulina has a vast array of beneficial properties. It has been shown to be effective in the treatment of allergies, anemia, cancer, high cholesterol, elevated blood sugar, viral infections, inflammatory conditions, liver damage, immunodeficiency, cardiovascular diseases, and other conditions ... In a 2002 Japanese study, 12 adult males were administered an oral hot water extract of spirulina, and the number and activity of their natural killer (NK) cells was measured before and after treatment. (NK cells destroy tumor cells by binding to them and delivering lethal chemicals that kill on contact.) At the study's end, there was a significant increase in the production and cancer-killing ability of these subjects' NK cells ... Spirulina also shows potential for decreasing the adverse effects of both chemotherapy and radiation"
  • Pond Scum Makes a Health Splash, Scientists Debate Immune Benefits of Spirulina Algae - WebMD, 12/11/00
  • Spirulina May Boost Immune Response - Medscape, 12/8/00 - "We found that nutrient-rich spirulina is a potent inducer of interferon-gamma (13.6-fold increase) and a moderate stimulator of both interleukin-4 and interleukin-1beta (3.3-fold increase)"

Abstract:

  • Exercise and spirulina control non-alcoholic hepatic steatosis and lipid profile in diabetic Wistar rats - Lipids Health Dis. 2011 May 15;10(1):77 - "The rats were divided into four groups: Diabetic Control (DC) - diabetic rats fed with a control diet and no physical exercise; Diabetic Spirulina (DS) - diabetic rats fed with a diet that included spirulina; Diabetic Spirulina and Exercise (DSE) - diabetic rats fed with a diet that included Spirulina and that exercised; and Diabetic Exercise (DE) - diabetic rats fed with a control diet and that exercised. Results The groups DS, DSE, and DE presented lower plasma concentrations of LDL cholesterol than DC, as well as lower levels of total liver lipids in groups DS, DSE, and DE in comparison to DC. Conclusion Thus, spirulina appears to be effective in reducing total circulating levels of LDL-cholesterol and hepatic lipids, alone or in conjunction with physical exercise in diabetic rats"
  • The effects of Spirulina on anemia and immune function in senior citizens - Cell Mol Immunol. 2011 Jan 31 - "Participants took a Spirulina supplementation for 12 weeks and were administered comprehensive dietary questionnaires to determine their nutritional regimen during the study. Complete cell count (CCC) and indoleamine 2,3-dioxygenase (IDO) enzyme activity, as a sign of immune function, were determined at baseline and weeks 6 and 12 of supplementation. Thirty study participants completed the entire study and the data obtained were analyzed. Over the 12-week study period, there was a steady increase in average values of mean corpuscular hemoglobin in subjects of both sexes. In addition, mean corpuscular volume and mean corpuscular hemoglobin concentration also increased in male participants. Older women appeared to benefit more rapidly from Spirulina supplements. Similarly, the majority of subjects manifested increased IDO activity and white blood cell count at 6 and 12 weeks of Spirulina supplementation. Spirulina may ameliorate anemia and immunosenescence in older subjects"
  • Antiinflammatory and antihyperalgesic activity of C-phycocyanin - Anesth Analg. 2009 Apr;108(4):1303-10 - "Pre- or posttreatment with C-PC (30 or 50 mg/kg, IP) significantly attenuated carrageenan-induced inflammatory nociception and the induction of iNOS and COX-2 at the late phase, (4 h) accompanied by an inhibition of the formation of TNF-alpha, prostaglandin E(2), nitrate and myeloperoxidase activity ... Based on these results, it is suggested that the inhibition of NO and prostaglandin E(2) over-production through suppressing iNOS and COX-2 induction and attenuation of TNF-alpha formation and neutrophil infiltration into inflammatory sites by C-PC may contribute, at least in part, to its antihyperalgesic activity"
  • Antihyperlipemic and antihypertensive effects of Spirulina maxima in an open sample of Mexican population: a preliminary report - Lipids Health Dis. 2007 Nov 26;6:33 - "the calculated values for cholesterol associated to low density lipoprotein (LDL-C) were significantly reduced by the Spirulina maxima ... significant differences were found comparing initial and final SYST-P and DIAST-P blood pressure in both male and female: SYST-P male 121 +/- 9 vs. 111 +/- 8 mm Hg (p < 0.01), DIAST-P male 85 +/- 6.5 vs. 77 +/- 9 mm Hg (p < 0.01); SYST-P female 120 +/- 9.5 vs. 109 +/- 11 mm Hg (p < 0.002), DIAST-P female 85 +/- 11 vs. 79 +/- 7.5 mm Hg"

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