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Home > Anti-aging Research > Phosphorus
Phosphorus
Note: Several years ago, I read somewhere that most people get too much phosphorus. I think that is probably why you don't see much on phosphorus supplementation. - Ben
News & Research:
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Link
between phosphate intake and heart disease demonstrated in new study -
Science Daily, 6/7/11 - "cholesterol deposits in the
wall of arteries are increased following a higher phosphate diet. This leads
to narrowing of the arteries, which is the cause of most heart attacks and
strokes ... Food high in phosphate includes biscuits, cakes, sweets, dairy
products and meats such as offal and veal" - Note: They left
out soda which is high in phosphate.
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Phosphorous in sodas and processed foods accelerates signs of aging, study
suggests - Science Daily, 4/26/10 - "high levels of phosphates may add more
"pop" to sodas and processed foods than once thought. That's because researchers
found that the high levels of phosphates accelerate signs of aging. High
phosphate levels may also increase the prevalence and severity of age-related
complications, such as chronic kidney disease and cardiovascular calcification,
and can also induce severe muscle and skin atrophy"
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Small Increases In Phosphorus Mean Higher Risk Of Heart Disease -
Science Daily, 115/09 - "Higher levels of phosphorus
in the blood are linked to increased calcification of the coronary arteries
-- a key marker of heart disease risk ... Even small increases in the blood
level of phosphorus predicted an increased risk of progressive CAC in these
apparently healthy adults ... The phosphorus-related increase in CAC was
comparable to that seen with traditional heart disease risk factors like
high blood pressure and high cholesterol"
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Chewing Chitosan-Loaded Gum Reduces Phosphate Levels in ESRD Patients -
Medscape, 2/16/09 - "Chewing chitosan-loaded gum
twice daily can significantly decrease salivary phosphate and serum
phosphate levels in hemodialysis patients and may help improve treatment for
hyperphosphatemia ... At week 1, the patients’ salivary phosphate levels had
decreased from 73.21 to 52.02 mg/dL (P < .01), and serum levels decreased
from 7.60 to 5.38 mg/dL (P < .00001). After 2 weeks, salivary phosphate
levels were reduced to 33.19 mg/dL (P < .00001) and serum levels decreased
to 5.25 mg/dL" - See
chitosan products at iHerb
 .
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Phosphorus additives pose ‘hidden’ danger to kidney patients - Nutra
USA, 2/11/09
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Common Food Additive Found To Increase Risk And Speed Spread Of Lung Cancer
- Science Daily, 12/29/08 - "a diet high in
inorganic phosphates, which are found in a variety of processed foods
including meats, cheeses, beverages, and bakery products, might speed growth
of lung cancer tumors and may even contribute to the development of those
tumors in individuals predisposed to the disease" - [WebMD]
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Phosphorus-lowering Drugs Linked To Lower Mortality In Dialysis Patients
- Science Daily, 12/17/08
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Higher Blood Phosphorus and Calcium Levels in Coronary Arteries -
Science Daily, 11/26/08 - "Higher serum phosphorus
levels, even within the normal range, may be a risk factor for coronary
artery atherosclerosis in healthy young adults"
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Boning Up - Better Health, 12/04 - "Don't overdo your phosphorus intake. Calcium is excreted when phosphorus levels are excessive"
- Regular Cola Consumption Linked to Lower Bone Density in Women - Medscape, 9/22/03 -
"Among the female subjects, regular cola drinkers had decreased BMD compared with the
infrequent drinkers. BMD was 2.3% lower in the trochanter, 3.3% lower in the femoral neck, and 5.1% lower in Ward's area ... When phosphoric acid comes packaged with other nutrients, it's absorbed
normally and everything is in balance. We think the problem with cola is that you're getting those doses of phosphoric acid without any calcium. It's not balanced, and that extra phosphorus binds with calcium and prevents it from being absorbed"
- Phosphorus Important for Bone Health in Elderly - New Hope Natural Media, 8/30/02 -
"Although most Americans consume 100% or more of the Recommended Dietary
Allowance for phosphorus, older individuals often reduce their total food intake and consume less of the high-phosphorus foods. While these dietary changes may not by themselves be enough to cause phosphorus deficiency, supplementing with large amounts of calcium could lead to a
phosphorus deficiency in people who are consuming marginal amounts of the mineral ... Taking extra phosphorus is not appropriate for individuals who already consume large amounts in their diets. In fact, much of the research on phosphorus intake has focused on the problem of excessive phosphorus intake leading to a
calcium deficiency"
- Bones Need Both Calcium and Phosphorus - WebMD, 3/20/02
Abstracts:
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Lower
concentrations of serum phosphorus within the normal range could be
associated with less calcification of the coronary artery in Koreans with
normal renal function - Am J Clin Nutr. 2011 Oct 26 -
"Serum phosphorus concentrations are associated with an increased risk of
cardiovascular disease (CVD) and mortality in patients with renal
insufficiency. This association has also been reported in Western
individuals without chronic kidney disease (CKD) ... Compared with the group
with a serum phosphorus concentration ≤3.3 mg/dL, the OR of an Agatston
score >100 in individuals with a serum phosphorus concentration >3.6 to ≤3.9
mg/dL was 3.89 (95% CI: 1.43, 10.63; P = 0.008) and in those with a serum
phosphorus concentration >3.9 mg/dL was 3.17 (95% CI: 1.19, 8.41; P = 0.021)
... A lower concentration of serum phosphorus within the normal range could
be associated with less calcification of the coronary artery in Koreans with
normal renal function"
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Once-Daily Extended-Release Niacin Lowers Serum Phosphorus Concentrations in
Patients With Metabolic Syndrome Dyslipidemia - Am J Kidney Dis. 2010
Sep 29 - Note: It doesn't have the abstract, just the title but it's
something I didn't know. Most people get too much phosphorus.
-
Is
Lowering Phosphate Exposure The Key To Preventing Arterial Stiffening With
Age? - Heart. 2009 Mar 24 - "Diets in affluent
populations are high in phosphate because of increased consumption of animal
protein and the use of phosphate containing preservatives. We suggest that
the consumption of a phosphate rich diet, exacerbated by the high prevalence
of chronic kidney disease found in ageing populations, accelerates the
development of arteriosclerosis. We hypothesise that reducing phosphate
intake will attenuate the progression of arterial stiffness with major
beneficial effects upon cardiovascular mortality and morbidity"
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Increased calcium intake does not completely counteract the effects of
increased phosphorus intake on bone: an acute dose-response study in healthy
females - Br J Nutr. 2007 Oct 1;:1-8 - "When P
intake was above current recommendations, increased Ca intake was beneficial
for bone, as indicated by decreased S-PTH concentration and bone resorption.
However, not even a high Ca intake could affect bone formation when P intake
was excessive"
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Relations of serum phosphorus and calcium levels to the incidence of
cardiovascular disease in the community - Arch Intern Med. 2007 May
14;167(9):879-85 - "Individuals
in the highest serum phosphorus quartile experienced a
multivariable-adjusted 1.55-fold CVD risk (95% confidence interval,
1.16%-2.07%; P = .004) compared with those in the lowest quartile ... Higher serum
phosphorus levels are associated with an increased CVD risk in individuals
free of CKD and CVD in the community"
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Phosphorus nutrition and the treatment of osteoporosis - Mayo Clin Proc. 2004 Jan;79(1):91-7
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