|
|
|
Welcome to the Quality Counts. For those health conscious consumers and medical professionals that are looking to purchase nutritional supplements, vitamins, herbs, learning about medications, losing weight, health food, low carbs, high protein nutrition, and exercise, you have come to the right place. Quality Counts serves both the medical practitioner and consumer interested in nutritional therapy and alternative medicine.
Home > Anti-aging Research > PGX™
PolyGlycopleX™ (PGX™)
Related Topics:
Specific Recommendations:
News & Research:
-
Cholesterol
& Statin Drugs - Life Extension Magazine, 11/04 -
"PGX™. A relatively small amount (one to three grams before each meal) of this highly viscous fiber blend of glucomannan, xanthan, and alginate may help
lower LDL and total cholesterol"
-
Novel
Fiber Limits Sugar Absorption - Life Extension Magazine, 9/04 -
"With the introduction of a new highly viscous fiber blend trademarked under the name PGX™, it may now be possible to achieve the multiple
documented benefits of fiber by swallowing only a few capsules before each meal. The longevity potential associated with reducing after-meal glucose and insulin blood levels, lowering total cholesterol and LDL, and losing some weight is enormous"
-
Novel
Fiber Limits Sugar Absorption - Life Extension Magazine, 9/04 -
"Life Extension recommends that people seeking to lose weight consume the following supplements: ... Chromium
polynicotinate 600-1000 mcg daily ... Conjugated linoleic acid (CLA) 3000-4000 mg daily ... PGX™ highly viscous fiber blend 1000-3000 mg 5-10 minutes before each meal with 8-16 ounces of water ... Consider asking your doctor to prescribe 500 mg two to three times daily of the
insulin-normalizing drug metformin"
- Solving Syndrome X - Dr. Murray's Natural Facts, 7/21/04 -
"PGX lowers after meal blood sugar levels by approximately 20 to 40% and also lowers insulin secretion by
approximately 40% producing a whole body insulin sensitivity index improvement of nearly 60%" - See
iHerb
or
Vitacost PGX products.
Abstracts:
-
Effects of
added PGX®, a novel functional fibre, on the glycaemic index of starchy foods
- Br J Nutr. 2011 Oct 10:1-4 - "Healthy subjects (n 10) consumed glucose sugar
(50 g in water × 3) and six starchy foods with a range of GI values (52-72)
along with 0 (inert fibre), 2·5 or 5 g granular PGX® dissolved in 250 ml water
... PGX® significantly reduced the GI of all six foods (P < 0·001), with an
average reduction of 19 % for the 2·5 g dose and 30 % for the 5 g dose,
equivalent to a reducing the GI by 7 and 15 units, respectively. Consuming small
quantities of the novel functional fibre PGX®, mixed with water at the start of
a meal, is an effective strategy to reduce the GI of common foods"
-
Effects of
PGX, a novel functional fibre, on acute and delayed postprandial glycaemia -
Eur J Clin Nutr. 2010 Oct 6 - "Granular PGX at breakfast time at doses of 2.5, 5
and 7.5 g reduced the incremental area under the curve by up to 50% in a linear
dose-response fashion (P<0.001). The granular form of PGX (5 g), but not the
capsules, reduced glycaemia by up to 28% when consumed from -45 to +15 min
(P<0.001). Capsules containing 3, 4.5 and 6 g PGX consumed with the evening meal
reduced glycaemia at breakfast by up to 28% (P<0.001)"
-
Reduction of
Postprandial Glycemia by the Novel Viscous Polysaccharide PGX, in a
Dose-Dependent Manner, Independent of Food Form - J Am Coll Nutr. 2010
Apr;29(2):92-8 - "The objective of the study therefore was to determine
palatability and effectiveness of escalating doses of PGX, a novel viscous
polysaccharide (NVP), in reducing postprandial glycemia when added to a liquid
and a solid meal ... Addition of NVP to the meal reduced blood glucose
incremental areas under the curve irrespective of dose, reaching significance at
the 7.5 g dose when added to glucose (p < 0.01), and at the 5 and 7.5 g doses
when added to WB + Marg (p < 0.001). The GI values of glucose with 0, 2.5, 5, or
7.5 g of NVP were (mean +/- standard error of the mean [SEM]) 100.0 +/- 0.0,
83.7 +/- 9.0, 77.7 +/- 8.2, and 72.5 +/- 5.9, respectively; the GI of the WB
alone, or of WB + Marg, with 0, 2.5, 5, or 7.5 g of NVP was 71.0 +/- 0.0, 66.8
+/- 3.0, 47.5 +/- 5.9, 37.3 +/- 5.9, and 33.9 +/- 3.6, respectively. CONCLUSION:
Addition of NVP to different food matrices is highly effective in lowering the
glycemic index of a food in a dose-responsive manner" - See Natural Factors, WellBetX PGX with Mulberry, 180 Capsules at iHerb.
-
Increased
plasma PYY levels following supplementation with the functional fiber
PolyGlycopleX in healthy adults - Eur J Clin Nutr. 2010 Jul 28 -
"A variety
of dietary fibers have been shown to alter satiety hormone gene expression and
secretion. The objective of this study was to examine plasma satiety hormone
concentrations in healthy subjects consuming either PolyGlycopleX (PGX) or
control (skim milk powder) for 21 days ... Primary outcomes measured at three
visits (V1, V2 and V3) were plasma active glucagon-like peptide-1 (GLP-1) total
ghrelin, peptide YY (PYY) and insulin. Results: There was a significant effect
of visit for fasting PYY with control participants experiencing decreased PYY
levels over time while PGX prevented this decline. When stratified by body mass
index (BMI), PGX increased fasting PYY levels from week 1 to week 3 compared
with control in participants with BMI <23 kg/m(2). There was a significant
effect of visit for fasting ghrelin with levels decreasing in both PGX and
control groups over time. No differences were detected in fasting GLP-1 levels.
Although there was a 14% reduction in fasting insulin between V1 and V3 with PGX
this was not significantly different from control" - Note: I don't know
how they determine that a 14% reduction isn't significant. See
PGX™ products at iHerb.
Related Searches:
70402
|
