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Home > Anti-aging Research > Pectin
Pectin
Specific Recommendations:
News & Research:
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Apple fibres may boost immune health: Study - Nutra USA, 3/3/10 -
"fed
low-fat diets supplemented with either soluble (pectin, 10 per cent of the diet)
or insoluble fibre (cellulose, 5 or 10 per cent of the diet) for six weeks. At
the end of this period the mice were challenged with an endotoxin to induce
sickness ... Two hours after [entotoxin] injection, the mice fed soluble fibre
were only half as sick as the other group, and they recovered 50 per cent
sooner. And the differences between the groups continued to be pronounced all
the way out to 24 hours" - [Abstract]
[Science
Daily]
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Pectin Power: Why Fruits And Vegetables May Protect Against Cancer's Spread
- Science Daily, 10/13/08 - "They have shown that a
fragment released from pectin, found in all fruits and vegetables, binds to
and is believed to inhibit galectin 3 (Gal3), a protein that plays a role in
all stages of cancer progression"
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Pectin shows potential against prostate cancer - Nutra USA, 8/22/07 -
"The new study looked at the effect of different
forms of pectin - commercially available fractionated pectin powder (FPP),
citrus pectin (CP), and pH-modified CP (PectaSol) - on hormone- (androgen)
responsive and androgen-independent human prostate cancer cells ... the FPP
induced apoptosis (programmed cell death) by about 40 fold, compared to
non-treated cells, for both types of cancer cell" - [Abstract]
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MCP
for Prostate Cancer - Life Extension Magazine, 3/04
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A
Commentary on Modified Citrus Pectin - Life Extension Magazine, 3/04
- Citrus Nutrient Helps Slow Prostate Cancer - WebMD, 12/16/03 -
"Every day, patients took 18 capsules of pectin: Each contained 14 grams of pectin, equaling 800 mg a day ...
Fourteen months later, 70% of the men had significant increases in the time it took to produce PSA -- it took longer for prostate cells to produce a doubling of blood PSA levels"
Abstracts:
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Dietary
Pectin Regulates the Levels of Inflammatory Cytokines and Immunoglobulins in
Interleukin-10 Knockout Mice - J Agric Food Chem. 2010 Oct 14 -
"Pectin has
protective, anti-inflammatory effects on inflammatory bowel disease (IBD), but
the exact mechanism is unknown ... Pectin treatment reduced expression of TNF-α
and GATA-3, an important transcription factor for the Th2 immune response. These
mice also expressed lower levels of IgE in the spleen and Peyer's patches (PP)
and lower IgG and IgM expression in PP. Interestingly, IL-10 deficiency resulted
in lower CD4(+) and CD8(+) populations in the spleen, mesenteric lymph node
(MLN), and PP; however, pectin counteracted these declines in the MLN and PP.
Therefore, dietary pectin downregulates the inflammatory response in the colon
by moderating the production of proinflammatory cytokines and immunoglobulins"
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Sickness behavior induced
by endotoxin can be mitigated by the dietary soluble fiber, pectin, through
up-regulation of IL-4 and Th2 polarization - Brain Behav Immun. 2010 Feb 6 -
"We show that a diet rich in soluble fiber protects mice from endotoxin-induced
sickness behavior by polarizing mice Th2 when compared to a diet containing only
insoluble fiber. Mice fed soluble fiber became less sick and recovered faster
from endotoxin-induced sickness behaviors than mice fed insoluble fiber ...
These data show that a diet rich in soluble fiber protects against endotoxin-induced
sickness behavior by polarizing mice Th2 and promoting alternative activation of
macrophages" - See
pectin products at iHerb.
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