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Home > Health Conditions > Neuropathic Pain
Neuropathic Pain/Neuropathy
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-
Vitamin E is
a MIF Inhibitor - Biochem Biophys Res Commun. 2012 Jan 18 -
"Macrophage
migration inhibitory factor (MIF) is known to contribute to the pathogenesis of
inflammatory hyperalgesia and neuropathic pain ... Vitamin E inhibits not only
the enzymatic activity of MIF but more importantly the biological function of
MIF. Our findings suggest that Vitamin E may be attenuating hyperalgesia and
reducing neuropathic pain at least in part by inhibiting MIF activity"
- See
Jarrow FamilE (contains all eight members of the vitamin E family, includes Tocomin) at iHerb
 .
-
Long-term
dietary antioxidant cocktail supplementation effectively reduces renal
inflammation in diabetic mice - Br J Nutr. 2011 Jun 3:1-8 -
"Diabetic
nephropathy is a serious complication for diabetic patients, yet the precise
mechanism that underlies the development of diabetic complications remains
unknown. We hypothesised that dietary antioxidant supplementation with single N-acetylcysteine
(NAC) or vitamin C combined with either vitamin E or vitamin E and NAC improves
diabetic renal inflammation through the modulation of blood glucose levels,
oxidative stress and inflammatory response. Experimental animals were treated
with alloxan monohydrate to induce diabetes. Mice were divided into five groups
and supplemented with single or a combination of antioxidants. Body weights and
blood glucose levels were measured once a week. After 8 weeks of dietary
antioxidant supplementation, mice were killed and blood urea N (BUN) and plasma
creatinine levels were measured to evaluate renal function. NF-κB protein was
indirectly demonstrated by the phosphorylated IκBα (pIκBα) level, and the
expressions of oxidative stress- and inflammatory response-related proteins were
also determined. We demonstrated that dietary antioxidant supplementation
decreased lipid peroxidation levels demonstrated by thiobarbituric acid-reacting
substances, BUN and plasma creatinine levels in diabetic kidneys. Moreover,
dietary antioxidant cocktail supplementation improved blood glucose levels and
selectively regulated the expressions of Cu-Zn superoxide dismutase, haeme
oxygenase-1, pIκBα, inducible NO synthase, cyclo-oxygenase-2 and C-reactive
protein in diabetic kidneys effectively. These findings demonstrated that
diabetic renal failure was associated with inflammatory responses induced by
hyperglycaemia. In addition, results in the study suggest that antioxidant
cocktail supplementation may have beneficial effects on diabetic nephropathy
through selective reduction of blood glucose levels and inflammatory response" -
See
NAC products at iHerb.
-
Efficacy and
safety of high-dose α-lipoic acid in the treatment of diabetic polyneuropathy
- Zhonghua Yi Xue Za Zhi. 2010 Sep;90(35):2473-2476 - "total symptom score (TSS)
... 73.27% patients with symptomatic polyneuropathy improved after treatment
with α-lipoic acid for 12 weeks versus 18.27% with placebo. TSS declined by 2.6
± 2.3 with α-lipoic acid. And it was more than 0.7 ± 1.4 versus placebo (P <
0.05). TSS decreased quickly after treatment with α-lipoic acid for 2 weeks (P <
0.05). And it was better than placebo. Individual symptom scores of pain,
extremity numbness, burning sensation or resting abnormal sensations were
significantly diminished as compared to those before treatment and placebo group
(all P < 0.05). Nerve conduction velocity had no change. HbA1c further decreased
at the end of trial after α-lipoic acid treatment (P < 0.05). The incidence
rates of adverse effects were 25.4% vs 11.8% in the treatment and control
groups. The major manifestation was burning sensation from throat to stomach
(12.7%)" - See
alpha lipoic acid products at iHerb.
-
Chromium
picolinate may lessen inflammation in diabetic nephropathy; Supplement linked to
decreased protein in the urine of diabetic mice - Science Daily, 9/22/10 -
"mice who received the supplement had lower levels of albuminuria (protein in
the urine), an indication of kidney disease ... the treated diabetic mice, who
were fed the diet with chromium picolinate, excreted about half as much albumin
compared to their untreated diabetic counterparts" - See
chromium products at iHerb.
-
alpha-Lipoic
acid protects diabetic apolipoprotein E-deficient mice from nephropathy - J
Diabetes Complications. 2010 Aug 26 - "LA supplementation markedly protected the
beta cells, reduced cholesterol levels, and attenuated albuminuria and
glomerular mesangial expansion in the diabetic mice. Renoprotection by LA was
equally effective regardless of whether the dietary supplementation was started
4 weeks before, simultaneously with, or 4 weeks after the induction of diabetes
by STZ. LA supplementation significantly improved DN and oxidative stress in the
diabetic mice. Severity of albuminuria was positively correlated with level of
thiobarbituric acid reactive substances (TBARs) in the kidney (r(2)=0.62,
P<.05). Diabetes significantly changed the kidney expression of Rage, Sod2,
Tgfb1 and Ctgf, Pdp2, nephrin, and Lias. LA supplementation corrected these
changes except that it further suppressed the expression of the Lias gene coding
for lipoic acid synthase" - See
Doctor's Best, Best Stabilized R-Lipoic Acid Na-RALA
at iHerb.
-
High-Dose B Vitamin
Therapy May Not Be Helpful in Diabetic Nephropathy - Medscape, 6/3/10
-
Omega-3
Polyunsaturated Fatty Acids in the Treatment of Kidney Disease - Am J Kidney
Dis. 2010 May 19 - "guidelines suggest that omega-3 polyunsaturated fatty acids
should be considered in progressive IgA nephropathy. Omega-3 polyunsaturated
fatty acids decrease blood pressure, a known accelerant of kidney disease
progression" - See
Mega Twin EPA at iHerb
and
Jarrow Max DHA at iHerb.
-
Omega-3 intakes may improve diabetic kidney health - Nutra USA, 4/12/10 -
"Albumin is the most abundant protein in human serum and in people with kidney
problems the protein leaks from the kidney into the urine. A level of 30 mg per
24 hours is reportedly representative of sufficient function ... people with a
higher average intake of omega-3s had albumin excretion levels 22.7 mg per 24
hours lower than people with the lowest average intakes of omega-3" - [Abstract] - See
Mega Twin EPA at iHerb
and
Jarrow Max DHA at iHerb.
-
Dietary
intake of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) and
diabetic nephropathy - cohort analysis of the Diabetes Control and Complications
Trial (DCCT) - Diabetes Care. 2010 Mar 31 - "In a mean follow-up of 6.5
years, we observed a lower mean UAER [difference 22.7 mg/24 hr (95% CI 1.6,
43.8)] in the top vs. bottom third of dietary n-3 LC-PUFAs, but found no
association with incident albuminuria ... Dietary n-3 LC-PUFAs appear inversely
associated with the degree, but not with the incidence of albuminuria in type 1
diabetes" - See
Mega Twin EPA at iHerb
and
Jarrow Max DHA at iHerb.
-
High-Dose N-Acetylcysteine Reduces Contrast Nephropathy - Medscape,
9/14/09 - "the odds of contrast-induced nephropathy
were 54% lower in patients randomized to high-dose N-acetylcysteine,
compared to those randomized to a control group" - See
NAC products at iHerb.
-
Metformin Linked to B12 Deficiency - WebMD, 6/8/09 -
"40% of type 2 diabetes patients using metformin had
vitamin B12 deficiency or were in the low-normal range for the essential
vitamin. And 77% of metformin users with vitamin B12 deficiency also had
peripheral neuropathy, a common form of nerve damage associated with type 2
diabetes" - See
B-12 products at iHerb.
-
Ginkgo Reduces Neuropathic Pain In Animal Studies - Science Daily,
6/5/09 - "For
both cold and pressure stimuli, pain responses were significantly reduced in
ginkgo-treated rats. This was so on before-and-after treatment comparisons
and on comparison of ginkgo-treated versus placebo-treated animals. The
higher the dose of ginkgo extract, the greater the pain-relieving effect.
Pain was reduced for at least two hours after ginkgo treatment" - See
ginkgo biloba products at iHerb.
-
Vitamin
B(12) may be more effective than nortriptyline in improving painful diabetic
neuropathy - Int J Food Sci Nutr. 2009 Feb 12:1-6 -
"In conclusion, vitamin B(12) is more effective than
nortriptyline for the treatment of symptomatic painful diabetic neuropathy" - See
vitamin B12 products a iHerb.
-
Role of
Acetyl-L-Carnitine in the Treatment of Diabetic Peripheral Neuropathy
(November) - Ann Pharmacother. 2008 Oct 21 -
"acetyl-L-carnitine (ALC) in the treatment of diabetic peripheral neuropathy
(DPN) ... Data on treatment of DPN with ALC support its use. It should be
recommended to patients early in the disease process to provide maximal
benefit. Further studies should be conducted to determine the effectiveness
of ALC in the treatment and prevention of the worsening symptoms of DPN"
- See
acetyl-l-carnitine products at iHerb.
-
Switching from pathogenetic treatment with alpha-lipoic acid to gabapentin and
other analgesics in painful diabetic neuropathy: a real-world study in
outpatients - J Diabetes Complications. 2008 Apr 8 - "The daily costs for alpha-lipoic acid were considerably lower than those for
gabapentin or several frequently used drug combinations. The frequency of
outpatient visits was 3.8 times per 3 months during the treatment period with
alpha-lipoic acid, while it increased to 7.9 per 3 months after switching to
gabapentin or the other pain medications. In conclusion, switching from
long-term treatment with alpha-lipoic acid to central analgesic drugs such as
gabapentin in painful diabetic neuropathy was associated with considerably
higher rates of side effects, frequencies of outpatient visits, and daily costs
of treatment. The pathogenic treatment option represents for the practicing
diabetologist an effective, safe, and cost-effective treatment option for the
majority of patients with diabetic polyneuropathy" - See alpha lipoic acid products at iHerb
 .
-
Alpha-Linolenic Acid May Lower Risk of Diabetic Peripheral Neuropathy -
Medscape, 1/7/08 - "Alpha-linolenic acid is an
omega-3 fatty acid found in many vegetable oils, including flaxseed,
walnuts, and canola oil ... Relative to adults in the lowest quintile of
alpha-linolenic acid intake (< 0.61 g/day), the multivariate-adjusted odds
of having peripheral neuropathy was 0.54 for subjects in the fourth quintile
(1.35 - 2.10 g/day) of intake and 0.40 for adults in the fifth quintile
(2.11 g/day or higher)" - See
flax seed products at iHerb.
-
The effect of alpha-lipoic acid on symptoms and skin blood flow in diabetic
neuropathy - Diabet Med. 2007 May 8 - "study suggests that alpha-lipoic
acid, a potent antioxidant, improves symptoms of diabetic neuropathy"
-
Oral
Treatment With {alpha}-Lipoic Acid Improves Symptomatic Diabetic Polyneuropathy:
The SYDNEY 2 trial - Diabetes Care. 2006 Nov;29(11):2365-2370 -
"Oral treatment with ALA for 5 weeks
improved neuropathic symptoms and deficits in patients with DSP. An oral dose of
600 mg once daily appears to provide the optimum risk-to-benefit ratio" -
See
iHerb
or Vitacost
alpha lipoic acid products.
-
Copper Deficiency May Be Cause of Mysterious Neuropathy - Doctor's Guide,
5/31/06 - "Unexplained neuropathy may be
the result of a copper deficiency ... Copper deficiency has long been associated
with anemia and neutropenia, but its neurological consequences have only
recently been recognized"
-
Treatment for diabetic mononeuropathy with alpha-lipoic acid - Int J
Clin Pract. 2005 Jun;59(6):645-50 -
"alpha-lipoic acid appears to be an effective drug in the treatment for not
only peripheral and autonomic diabetic neuropathy, but also diabetic mononeuropathy of the cranial nerves leading to full recovery of the
patients" - See
iHerb
or Vitacost
alpha lipoic acid products.
-
Benfotiamine in the treatment of diabetic polyneuropathy--a three-week
randomized, controlled pilot study (BEDIP study) - Int J Clin Pharmacol
Ther. 2005 Feb;43(2):71-7 - "A
statistically significant (p = 0.0287) improvement in the neuropathy score
was observed in the group given active drug when compared to the
placebo-treated controls"
- Common Nutrient May Ease Diabetic Pain - WebMD, 1/6/05 -
"a 1,000 milligrams three times a day of acetyl-L-carnitine was effective in
relieving pain caused by nerve damage associated with the condition"
- Supplemental Carnitine May Be Helpful in Diabetic Neuropathy - Medscape, 1/3/05 -
"Pain as the most bothersome symptom significantly improved
with ALC"
- Acetyl-L-Carnitine Improves Pain, Nerve Regeneration, and Vibratory Perception in Patients With Chronic Diabetic Neuropathy: An analysis of two randomized
placebo-controlled trials - Diabetes Care. 2005 Jan;28(1):89-94 -
"ALC treatment is efficacious in alleviating symptoms, particularly pain, and improves nerve fiber regeneration and vibration perception in patients with
established diabetic neuropathy"
- Needle Away Neuropathy? - Dr. Weil, 4/12/04
- Antioxidant [alpha]-Lipoic Acid Provides Relief for Diabetic Polyneuropathy - Doctor's Guide, 6/20/03 -
"After 3 weeks,
alpha-lipoic acid had a 24.1% improvement over placebo ... for TSS [Total Symptom Score] and 16.0% for NIS [Neuropathy Impairment Score]" -
See
iHerb
or Vitacost
alpha lipoic acid products.
- Alpha Lipoic Acid Helping the Fight against Diabetes - Physician's Weekly, 5/12/03 -
"the over-the-counter antioxidant supplement
alpha lipoic acid has been effective against the burning, numbness and pain that often is associated with diabetic neuropathy. The antioxidant works mainly as a pain medication and was clinically shown to have few side effects" - See
iHerb
or Vitacost
alpha lipoic acid products.
- Antioxidant Soothes Diabetic Neuropathy - WebMD, 4/11/03 -
"Alpha lipoic acid seems to actually change the metabolism of the nerve
or blood supply to the nerve ... It is a very strong antioxidant and it is assumed that oxidation plays a role in the development of diabetes ... This means the substance -- produced in very small amounts by the body and also found in foods such as potatoes and red meat -- protects against damage by cell-ravaging
"free radicals." This oxidation process is implicated in various diseases, including heart disease, cancer, and neurologic conditions including Parkinson's and Alzheimer's ... alpha lipoic acid improves the function of cell
"transporters" that carry and distribute glucose. "This helps insulin do its role,"" - See
iHerb
or Vitacost
alpha lipoic acid products.
- B-Vitamins Prove Effective In Relieving Chronic Pain - Intelihealth, 4/10/03 -
"B-vitamins, such as thiamin
(B1), pyridoxine (B6), and cyanocobalamin (B12), have been proven to be clinically effective in treating various painful conditions such as lumbago, sciatica, trigeminal
neuralgia, facial paralysis and optic neuritis as acting as an analgesia (pain reliever)"
- Alpha-Lipoic Acid Helpful in Diabetic Neuropathy - Medscape, 3/7/03 -
"Alpha-lipoic acid (ALA) rapidly and significantly reduces sensory
symptoms and pain of diabetic neuropathy" - Note: ALA and acetyl-l-carnitine were supplements discussed in the 2/19/02 issue of the Proceedings of the National Academy of Sciences indicating that it
may slow or reversed aging in mice. See
iHerb
or Vitacost
alpha lipoic acid products.
- Enzymes Can Hasten Pain Relief - Nutrition Science News, 2/01
- The Chemistry of Pain - Nutrition Science News, 2/01
- Persistent Pain - Nutrition Science News, 10/99
-
Effectiveness of different benfotiamine dosage regimens in the treatment of
painful diabetic neuropathy - Arzneimittelforschung. 1999
Mar;49(3):220-4 - "An overall
beneficial therapeutic effect on the neuropathy status was observed in all
three groups during the study, and a significant improvement in most of the
parameters studied appeared already at the 3rd week of therapy (p < 0.01).
The greatest change occurred in the group of patients receiving the high
dose of benfotiamine"
- Chronic Joint Pain - Nutrition Science News, 1/99
CME:
General Information:
Other News:
-
Inhibition of the receptor for advanced glycation endproducts (RAGE)
protects pancreatic β-cells - Biochem Biophys Res Commun. 2010 Nov 24 -
"Advanced glycation endproducts (AGEs) and the
receptor for AGEs (RAGE) have been linked to the pathogenesis of diabetic
complications, such as retinopathy, neuropathy, and nephropathy. AGEs may
induce β-cell dysfunction and apoptosis, another complication of diabetes
... Inhibition of RAGE prevented AGE-induced pancreatic β-cell apoptosis,
but could not restore the function of glucose stimulated insulin secretion
(GSIS) in rat islets. In summary, the results of the present study
demonstrate that AGEs are integrally involved in RAGE-mediated apoptosis and
impaired GSIS dysfunction in pancreatic β-cells. Inhibition of RAGE can
effectively protect β-cells against AGE-induced apoptosis, but can not
reverse islet dysfunction in GSIS"
-
Effects
of angiotensin II receptor blockers on diabetic nephropathy - J
Hypertens. 2009 Jul;27 Suppl 5:S15-21 - "Key
beneficial effects of ARBs and ACE inhibitors throughout the kidney disease
continuum are primarily explained by blood pressure lowering effects and
partially by their direct blockade of angiotensin II. Recent studies have
shown that telmisartan, an ARB with high lipophilicity and the longest
half-life compared with other ARBs, provides benefits on markers of
cardiovascular risk, that is, microalbuminuria and slowing of early-stage
nephropathy"
-
Triglycerides Implicated in Diabetic Neuropathy - Doctor's Guide,
5/22/09
-
Microalbuminuria Reduction with Telmisartan in Normotensive and Hypertensive
Japanese Patients with Type 2 Diabetes: A Post-Hoc Analysis of the Incipient
to Overt: Angiotensin II Blocker, Telmisartan, Investigation on Type 2
Diabetic Nephropathy (INNOVATION) Study - Hypertens Res. 2008
Apr;31(4):657-64 - "The patients treated with either
dose of telmisartan showed lower transition rates from microalbuminuria to
overt nephropathy compared to the placebo group. In addition, more patients
on telmisartan reverted to normoalbuminuria (UACR<30 mg/g creatinine): 15.5%
of the 40 mg group, 19.6% of the 80 mg group, and 1.9% of the placebo group
... Side effects did not differ among the groups. The present study
demonstrates that telmisartan prevents the progression of microalbuminuria
(in some cases induces remission of albuminuria) in normotensive Japanese
patients with type 2 diabetes. Telmisartan is shown to be safe and well
tolerated in these patients"
-
Protein Found That May Provide Relief From Neuropathic Pain - Science
Daily, 12/5/07
-
Pain-free Window Into Painful Neuropathies - Science Daily, 12/5/07
-
Renoprotective effect of the addition of losartan to ongoing treatment with
an Angiotensin converting enzyme inhibitor in type-2 diabetic patients with
nephropathy - Hypertens Res. 2007 Oct;30(10):929-35 -
"During the 12-month treatment, addition of losartan
or addition of an ACE-I to the treatment protocol reduced systolic blood
pressure (SBP) by 10% and 12%, diastolic blood pressure (DBP) by 7% and 4%,
and urinary albumin excretion by 38% and 20% of the baseline value,
respectively. However, the effects on both BP and urinary albumin were not
significantly different between the two therapies. In conclusion, addition
of losartan or an ACE-I to an ongoing treatment with an ACE-I, or addition
of an ACE-I to ongoing treatment with a conventional antihypertensive were
equally effective at reducing the urinary albumin excretion and BP, and
provided renal protection in patients with type-2 diabetic nephropathy"
-
Thiazolidinediones: A novel class of drugs for the prevention of diabetic
nephropathy? - Kidney Int. 2007 Dec;72(11):1301-1303 -
"Miyazaki et al. report that rosiglitazone, a
thiazolidinedione insulin sensitizer and a potent peroxisome proliferator-activated
receptor gamma agonist, not only effectively improves glycemic control but
also halts progression of albuminuria in type 2 diabetic patients with
early-stage diabetic nephropathy. These findings could offer a new
prevention of diabetic nephropathy in insulin-resistant diabetic patients"
-
Common Drugs Cut Diabetes Nerve Damage - WebMD, 6/22/07 -
"protection was 35% for statins and 48% for fibrates
-- statistically the same protection -- and these effects were independent
of blood sugar control, height, age, other things associated with
neuropathy"
-
Amitriptyline Commonly Prescribed for Neuropathy Despite Contraindications
- Doctor's Guide, 5/29/06
-
Lacosamide May Provide Treatment Option for Painful Distal Diabetic
Neuropathy - Doctor's Guide, 4/7/06
-
Local Anesthetics Are Effective For Neuropathic Pain - Science Daily,
10/26/05
-
Ruboxistaurin May Improve Diabetic Nephropathy: Presented at ADA -
Doctor's Guide, 6/14/05
-
Pregabalin Cuts Pain in Tough-To-Treat Patients With Neuropathic Pain and
Fibromyalgia Syndrome - Doctor's Guide, 4/13/05
- FDA Approves New Pain Reliever - WebMD, 1/3/05
-
Pregabalin Appears Benefit Patients With Peripheral Neuropathic Pain - Doctor's Guide, 9/22/04
-
Lyrica (Pregabalin) Offers Sustained Relief Of Peripheral Neuropathic Pain - Doctor's Guide, 9/8/04
- Lidocaine Patch Safe and Effective for Diabetic Neuropathic Pain - Medscape, 6/24/04
-
Painful Diabetic Neuropathy Often Inadequately Treated - Doctor's Guide, 6/7/04
-
Pregabalin Shows Sustained Relief of Diabetic Neuropathic Pain - Doctor's Guide, 6/7/04
-
Duloxetine Effective for Diabetic Neuropathic Pain - Clinical Psychiatry News, 6/04
-
Duloxetine May Be Effective for Treatment of Pain Associated With Diabetic Neuropathy - Doctor's Guide, 3/5/04
-
Neuropathic Pain: Guidelines Simplify Management - Clinical Psychiatry News, 3/04
-
Topiramate Used for Successful Treatment of Diabetic Peripheral Neuropathy: a Case Report - Doctor's Guide, 9/17/03
-
Duloxetine Relieves Pain Associated With Diabetic Neuropathy - Doctor's Guide, 8/26/03
-
Effective Treatments Available for Diagnosed Diabetic Neuropathy - Doctor's Guide, 7/3/03
-
Neuropathic Pain: Anticonvulsants and Antidepressants are Effective Adjuvant Analgesics - Physician's Weekly, 5/5/03
-
Relieve Range of Neuropathic Pain in Diabetics - Clinical Psychiatry News, 4/03
-
Controlled-Release Oxycodone Helps Resolve Sleep Problem in Patients with Diabetic Neuropathy - Doctor's Guide, 2/21/03
-
Glucose Tolerance Test Advised For Idiopathic Neuropathy - Doctor's Guide, 1/30/03
-
Heavy Proteinuria May Speed Progression Of Diabetic Nephropathy - Doctor's Guide, 1/13/03
-
Lidoderm (Lidocaine 5%) Patch Provides Effective Analgesia for Painful Diabetic Neuropathy - Doctor's Guide, 12/13/02
-
Range-Of-Motion Exercise Program May Help Prevent Diabetic Neuropathic Ulceration - Doctor's Guide, 10/30/02
- Diabetic Neuropathy, Gastropathy Respond to New Treatments - Medscape, 10/3/02
- Spray [ISDN] Eases Diabetic Foot Pain - WebMD, 10/3/02 -
"Although the exact cause of diabetic neuropathy is unknown, researchers believe the nerve damage
is related to an impaired ability to generate nitric oxide (NO). NO is used by the body to encourage healthy blood flow and oxygen circulation"
-
C-Peptide May Improve Sub-clinical Neuropathy in Type I Diabetics - Doctor's Guide, 9/4/02
-
Quinapril and Losartan Effectively Treat Diabetic Autonomic Neuropathy, Improve Left Ventricular Function - Doctor's Guide, 9/4/02
- Insulin Resistance Best Predictor of Diabetic Nephropathy - Medscape, 9/3/02
-
Zonegran (Zonisamide) May Be Effective Second-line Treatment for Neuropathic Pain - Doctor's Guide, 8/21/02
-
Intravenous Adenosine Effective For Control Of Neuropathic Pain - Doctor's Guide, 8/21/02
-
Lidocaine 5% Patch May Play Role in Treatment of Painful Diabetic Neuropathy - Doctor's Guide, 8/20/02
-
PKS-beta Inhibitor a "Breakthrough" for Diabetic Peripheral Neuropathy - Doctor's Guide, 6/18/02
- IVIG Effective in Diabetic-Related Inflammatory Neuropathy - Medscape, 6/5/02
-
Dextromethorphan Effective in Select Patients With Painful Diabetic Neuropathy - Doctor's Guide, 5/22/02
-
Lidoderm (Lidocaine Patch 5%) Effective for Neuropathic Pain - Doctor's Guide, 4/17/02
-
Combination ACE Inhibitors and Angiotensin II Blockers Decreases Proteinuria in Patients with Diabetic Nephropathy - Doctor's Guide, 4/11/02
- Lamotrigine Controls Pain In Patients With Polyneuropathy - Doctor's Guide, 10/2/01
- Lamictal (Lamotrigine) Relieves Pain of Diabetic Neuropathy - Doctor's Guide, 9/4/01
- Controlled-Release OxyContin (Oxycodone) Provides Analgesia In Painful Diabetic Neuropathy - Doctor's Guide, 6/24/01
- Stubborn Neuropathic Pain Responds to Buproprion - Doctor's Guide, 6/22/01
- Irbesartan Delays Nephropathy In Diabetic Patients - Doctor's Guide, 6/17/01
- Enzyme Therapy Effective, Safe for Fabry Disease - Doctor's Guide, 6/6/01
- Antihypertensive Control Needed To Delay Progression Of Diabetic Neuropathy - Doctor's Guide, 4/6/01 -
"Proper control of blood pressure is the single most important factor in delaying the progression of
diabetic neuropathy ... majority of such patients require more than a single antihypertensive agent to achieve adequate BP control (£ 130/80)"
- Higher Dose Of Duraclon (Clonidine) Now Available For Severe Neuropathic Pain - Doctor's Guide, 3/2/00
- Venlafaxine Has Role In Painful Diabetic Neuropathy - Doctor's Guide, 6/11/00
- Memantine reduces neuropathic pain in diabetics - Doctor's Guide, 5/3/00
- Memantine Significantly Reduces Peripheral Neuropathy Pain In Diabetics - Doctor's Guide, 1/25/00
- Neurontin Significantly Reduces Chronic Neuropathic Pain - Doctor's Guide, 12/23/98
- Severe Shingles Pain Relieved With Anti-Convulsant Drug Gabapentin - Doctor's Guide, 12/2/98
- Gabapentin Effective At Managing Pain Of Diabetic Neuropathy - Doctor's Guide, 12/1/98
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