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Welcome to the Quality Counts. For those health conscious consumers and medical professionals that are looking to purchase nutritional supplements, vitamins, herbs, learning about medications, losing weight, health food, low carbs, high protein nutrition, and exercise, you have come to the right place. Quality Counts serves both the medical practitioner and consumer interested in nutritional therapy and alternative medicine.

Home > Health Conditions > Menopause

Menopause

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  • Menopause pill may boost sex life - USATODAY.com, 12/20/11 - "This is the first evidence that low doses of DHEA (dehydroepiandrosterone), a hormone secreted by the adrenal glands, can help sexual function as well as menopausal symptoms ... women taking DHEA had a statistically significant increase in sexual interest and activity, with similar results for women in the HRT group. Sexual activity was also higher among the women taking tiboline, but the increase was not statistically significant" - See DHEA products at iHerb.
  • Effects of red ginseng supplementation on menopausal symptoms and cardiovascular risk factors in postmenopausal women: a double-blind randomized controlled trial - Menopause. 2011 Oct 24 - "The aim of this study was to evaluate the effects of red ginseng (RG) on menopausal symptoms and cardiovascular risk factors in postmenopausal women ... either an RG group (supplemented with 3 g of RG, including 60 mg of ginsenosides, per day) or a placebo group for 12 weeks ... Significant improvements in the Kupperman index (P = 0.032) and in the menopause rating scale (P = 0.035) scores were observed in the RG group compared with the placebo group. Total cholesterol (P = 0.009) and low-density lipoprotein cholesterol (P = 0.015) significantly decreased in the group receiving RG. The RG group also showed a significant decrease in carotid intima-media thickness (P = 0.049). Serum estradiol levels were not influenced by RG supplementation" - See Panax ginseng (red ginseng) products at iHerb.
  • Valerian may ease menopausal sleep woes - msnbc.com, 8/30/11 - "For the new study, researchers in Iran randomly assigned 100 postmenopausal women with insomnia to take either two valerian capsules or inactive placebo capsules every day for a month ... Overall, the study found, 30 percent of the women assigned to valerian reported an improvement in their sleep quality -- which includes factors like how long it takes to fall asleep at night and how often a person wakes up overnight ... In contrast, only four percent of women taking the placebo reported better sleep ... Women in this study reported no side effects ... Women in the current study took two valerian capsules a day, each containing 530 milligrams of valerian root extract. Both the valerian and placebo capsules they used were made specifically for the study ... A recent report by ConsumerLab.com, an independent testing company, found that of nine valerian supplements sold in the U.S., five had lower amounts of the herb than indicated on the packaging. That included one product with no valerian in it at all" - See Valerian Nighttime (my favorite) at iHerb.
  • Vitamin D intake from foods and supplements and depressive symptoms in a diverse population of older women - Am J Clin Nutr. 2011 Aug 24 - "After age, physical activity, and other factors were controlled for, women who reported a total intake of ≥800 IU vitamin D/d had a prevalence OR for depressive symptoms of 0.79 (95% CI: 0.71, 0.89; P-trend < 0.001) compared with women who reported a total intake of <100 IU vitamin D/d. In analyses limited to women without evidence of depression at baseline, an intake of ≥400 compared with <100 IU vitamin D/d from food sources was associated with 20% lower risk of depressive symptoms at year 3 (OR: 0.80; 95% CI: 0.67, 0.95; P-trend = 0.001). The results for supplemental vitamin D were less consistent, as were the results from secondary analyses that included as cases women who were currently using antidepressant medications ... Overall, our findings support a potential inverse association of vitamin D, primarily from food sources, and depressive symptoms in postmenopausal women" - See vitamin D products at iHerb.
  • Eating protein throughout the day preserves muscle and physical function in dieting postmenopausal women, study suggests - Science Daily, 8/10/11 - "higher protein intake during weight loss can offset negative effects on muscle mass by maintaining more muscle relative to the amount of weight lost. Women who ate more protein lost 3.9 percent more weight and had a relative gain of 5.8 percent more thigh muscle volume than woman who did not ... 31 healthy, postmenopausal obese women were divided into two groups. Each group followed a 1,400-calorie weight-loss diet based on USDA's My Pyramid, but one group received a powdered whey protein supplement in the morning and again in the afternoon or evening; the other received a placebo that contained carbohydrates ... We hypothesize that more vigorous exercise -- in particular, resistance training -- would preserve even more muscle" - See whey products at iHerb or try the yogurt recipe at the top of my yogurt page.
  • Increased Consumption of Dairy Foods and Protein during Diet- and Exercise-Induced Weight Loss Promotes Fat Mass Loss and Lean Mass Gain in Overweight and Obese Premenopausal Women - J Nutr. 2011 Jul 20 - "Weight loss can have substantial health benefits for overweight or obese persons; however, the ratio of fat:lean tissue loss may be more important. We aimed to determine how daily exercise (resistance and/or aerobic) and a hypoenergetic diet varying in protein and calcium content from dairy foods would affect the composition of weight lost in otherwise healthy, premenopausal, overweight, and obese women. Ninety participants were randomized to 3 groups (n = 30/group): high protein, high dairy (HPHD), adequate protein, medium dairy (APMD), and adequate protein, low dairy (APLD) differing in the quantity of total dietary protein and dairy food-source protein consumed: 30 and 15%, 15 and 7.5%, or 15 and <2% of energy, respectively. Body composition was measured by DXA at 0, 8, and 16 wk and MRI (n = 39) to assess visceral adipose tissue (VAT) volume at 0 and 16 wk. All groups lost body weight (P < 0.05) and fat (P < 0.01); however, fat loss during wk 8-16 was greater in the HPHD group than in the APMD and APLD groups (P < 0.05). The HPHD group gained lean tissue with a greater increase during 8-16 wk than the APMD group, which maintained lean mass and the APLD group, which lost lean mass (P < 0.05). The HPHD group also lost more VAT as assessed by MRI (P < 0.05) and trunk fat as assessed by DXA (P < 0.005) than the APLD group. The reduction in VAT in all groups was correlated with intakes of calcium (r = 0.40; P < 0.05) and protein (r = 0.32; P < 0.05). Therefore, diet- and exercise-induced weight loss with higher protein and increased dairy product intakes promotes more favorable body composition changes in women characterized by greater total and visceral fat loss and lean mass gain" - Note:  See the yogurt recipe on my yogurt page.
  • Effect of valerian on sleep quality in postmenopausal women: a randomized placebo-controlled clinical trial - Menopause. 2011 Jul 14 - "About 50% of postmenopausal women experience sleep disturbances such as insomnia ... A randomized, triple-blind, controlled trial design was used for this study. Participants consisted of 100 postmenopausal women aged 50 to 60 years who were experiencing insomnia. A demographic data form and the Pittsburgh Sleep Quality Index were used to collect data. The women were randomly divided into two groups. Each group received either 530 mg of concentrated valerian extract or a placebo twice a day for 4 weeks. Descriptive and inferential statistics were used to analyze the data ... A statistically significant change was reported in the quality of sleep of the intervention group in comparison with the placebo group (P < 0.001). Also, 30% of the participants in the intervention group and 4% in the placebo group showed an improvement in the quality of sleep" - Note:  My sleep combo is two Nature's Way, Valerian Nighttime, Odor Free, 100 Tablets, one Jarrow Formulas, Theanine 200, 200 mg, 60 Capsules and three Source Naturals, Melatonin, Peppermint Flavored Sublingual, 1 mg, 300 Tablets.
  • Myo-inositol in Postmenopausal Women With Metabolic Syndromed (printer-friendly) - Medscape, 2/7/11 - "In conclusion, this first report concerning myo-inositol supplementation for 6 months in postmenopausal women affected by metabolic syndrome demonstrated that it may improve some of the metabolic features of the syndrome such as carbohydrate metabolism, lipid profile, and blood pressure. Further studies and a longer time of treatment are needed to determine if the improvement in risk markers might provide a decrease in cardiovascular morbidity among these women" - See Inositol products at iHerb.
  • Protective effects of dehydroepiandrosterone on atherosclerosis in ovariectomized rabbits via alleviating inflammatory injury in endothelial cells - Atherosclerosis. 2010 Aug 3 - "The risk for atherosclerosis is increased in postmenopausal women. Dehydroepiandrosterone (DHEA) is postulated to have anti-atherogenic properties ... DHEA administration alleviates efficiently the early pathologic damage of atherosclerosis, increases the serum NO level, and up-regulates the endothelial cell estrogen receptor (ER) expression of ovariectomized rabbits. DHEA in vitro significantly promotes NO synthesis, suppresses MDA and MCP-1 secretion of endothelial cells, and decreases ICAM-1, VCAM-1 and E-selectin expression in HUVECs; neither selective ERα antagonist (methyl-piperidino-pyrazole, MPP) nor ERβ antagonist (R,R-tetrahydrochrysene, R,RTHC) can abolish these effects. Furthermore, DHEA reduces CCR2, LFA-1 and VLA-4 expression in U937 cells, which in turn inhibits the adherence of monocytes to the injured endothelial cells. DHEA significantly decreased the LPS-induced NF-κB transcription" - See DHEA products at iHerb.
  • Omega-3 fatty acids for major depressive disorder associated with the menopausal transition: a preliminary open trial - Menopause. 2010 Oct 27 - "The pretreatment and final mean MADRS scores were 24.2 and 10.7, respectively, reflecting a significant decrease in MADRS scores (P < 0.0001). The response rate was 70% (MADRS score decrease of ≥50%), and the remission rate was 45% (final MADRS score of ≤7). Responders had significantly lower pretreatment docosahexaenoic acid levels than nonresponders did (P = 0.03). Hot flashes were present in 15 (75%) participants. Among those with hot flashes at baseline, the number of hot flashes per day improved significantly from baseline (P = 0.02) and Hot Flash Related Daily Interference Scale scores decreased significantly ... These data support further study of omega-3 fatty acids for major depressive disorder and hot flashes in women during the menopausal transition" - See Mega Twin EPA at iHerb and Jarrow Max DHA at iHerb.
  • Effects of myo-inositol supplementation in postmenopausal women with metabolic syndrome: a perspective, randomized, placebo-controlled study - Menopause. 2010 Aug 31 - "Myo-inositol plus diet improved systolic and diastolic blood pressure, HOMA index, cholesterol, and triglyceride serum levels with highly significant differences, compared with the groups treated only with diet and placebo. In the group treated with myo-inositol, a decrease in diastolic blood pressure (-11%), HOMA index (-75%), and serum triglycerides (-20%) and an improvement in high-density lipoprotein cholesterol (22%) were shown ... CONCLUSIONS: Supplementation with myo-inositol may be considered a reliable option in the treatment of metabolic syndrome in postmenopausal women" - Note:  See raysahelian.com/inositol.html  and http://en.wikipedia.org/wiki/Inositol which claim myo-inositol and inositol are the same.  See inositol products at iHerb.
  • Isoflavones decrease insomnia in postmenopause - Menopause. 2010 Aug 19 - "Polysomnography revealed a significant increase in sleep efficiency in the isoflavone group (from 77.9% to 83.9%) when compared with the placebo group (from 77.6% to 81.2%). Isoflavones induced a decrease in the intensity and number of hot flashes and the frequency of insomnia: among the women in the placebo group, 94.7% had moderate or intense insomnia at the beginning of the study, compared with 63.2% at the end, whereas in the isoflavone group, these percentages were 89.5% and 36.9%, respectively" - See isoflavone products at iHerb.
  • Red clover extract: a source for substances that activate peroxisome proliferator-activated receptor alpha and ameliorate the cytokine secretion profile of lipopolysaccharide-stimulated macrophages - Menopause. 2010 Feb 5 - "In lipopolysaccharide-stimulated macrophages, red clover extract and its compounds reduced the secretion of proinflammatory cytokines, interleukin-6 and tumor necrosis factor alpha, increased the secretion of the anti-inflammatory interleukin-10, and/or reduced the expression of nuclear factor-kappaB, inducible nitric oxide synthase, and/or cyclooxygenase 2. Tumor necrosis factor alpha production was most efficiently reduced by biochanin A and genistein. Interleukin-6 levels were most efficiently reduced by genistein and equol. CONCLUSIONS:: Owing to its PPARalpha activation and modulation of the secreted cytokine profile, red clover extract is a putative candidate for preventing atherosclerosis and, thus, cardiovascular disease" - See Trinovin (for men), Promensil (for women) at iHerb.
  • Isoflavone Use May Improve Endothelial Function in Postmenopausal Women - Medscape, 12/11/09 - "In the overall analysis, isoflavone use significantly increased FMD"
  • Effects of a Combination of Hypericum perforatum and Vitex agnus-castus on PMS-Like Symptoms in Late-Perimenopausal Women: Findings from a Subpopulation Analysis - J Altern Complement Med. 2009 Sep;15(9):1045-8 - "At the end of the 16-week treatment phase, analyses of covariance showed the herbal combination to be superior to placebo for total PMS-like scores (p = 0.02), PMS-D (p = 0.006), and PMS-C clusters (p = 0.027). The active treatment group also showed significant reductions in the anxiety (p = 0.003) and hydration (p = 0.002) clusters, using paired-samples t tests. Results of trend analyses showed significant treatment group effects across the five phases for total PMS and all subscales, all in the clinically expected direction" - See Kira® (LI 160 extract) St. John's wort at iHerb and chaste berry products at iHerb.
  • 10 Ways to Ease Those Menopause Symptoms - US News and World Report, 9/8/09
  • Curcumin delays development of medroxyprogesterone acetate-accelerated 7,12-dimethylbenz[a]anthracene-induced mammary tumors - Menopause. 2009 Jul 22 - "Combined hormone therapy (HT) containing estrogen and progestin (medroxyprogesterone acetate [MPA]) leads to increased risk of breast cancer in postmenopausal women, compared with HT regimens containing estrogen alone or placebo ... Treatment with curcumin delayed the first appearance of MPA-accelerated tumors by 7 days, decreased tumor incidence by the end of the experiment, and reduced tumor multiplicity in DMBA-induced MPA-accelerated tumors. Curcumin also prevented many of the gross histological changes seen in the MPA-treated mammary gland. Immunohistochemical analyses of mammary tumors showed that curcumin decreased MPA-induced VEGF induction in hyperplastic lesions, although it did not affect the levels of estrogen and progesterone receptors" - See curcumin/turmeric products at iHerb.
  • Comparison of dietary conjugated linoleic acid with safflower oil on body composition in obese postmenopausal women with type 2 diabetes mellitus - Am J Clin Nutr. 2009 Jun 17 - "Supplementation with CLA reduced body mass index (BMI) (P = 0.0022) and total adipose mass (P = 0.0187) without altering lean mass. The effect of CLA in lowering BMI was detected during the last 8 wk of each 16-wk diet period. In contrast, SAF had no effect on BMI or total adipose mass but reduced trunk adipose mass (P = 0.0422) and increased lean mass (P = 0.0432). SAF also significantly lowered fasting glucose (P = 0.0343) and increased adiponectin (P = 0.0051). No differences were observed in dietary energy intake, total fat intake, and fat quality in either diet period for either intervention. CONCLUSIONS: Supplementation with CLA and SAF exerted different effects on BMI, total and trunk adipose mass, and lean tissue mass in obese postmenopausal women with type 2 diabetes" - See CLA products at iHerb.
  • Serum 25-hydroxyvitamin D is related to indicators of overall physical fitness in healthy postmenopausal women - Menopause. 2009 Jun 6 - "Serum 25(OH)D was the common contributor to physical fitness indices (androidal fat mass, lean mass, balance, handgrip strength) in healthy postmenopausal women" - See vitamin D products at iHerb.
  • Conjugated Linoleic Acids Reduce Body Fat in Healthy Postmenopausal Women - J Nutr. 2009 Jun 3 - "Isomers of conjugated linoleic acids (CLA) reduce fat mass (FM) and increase insulin sensitivity in some, but not all, murine studies. In humans, this effect is still debatable. In this study, we compared the effect of 2 CLA supplements on total and regional FM assessed by dual energy X-ray absorptiometry, changes in serum insulin and glucose concentrations, and adipose tissue (AT) gene expression in humans. In a double-blind, parallel, 16-wk intervention, we randomized 81 healthy postmenopausal women to 1) 5.5 g/d of 40/40% of cis9,trans11-CLA (c9,t11-CLA) and trans10,cis12-CLA (t10,c12-CLA) (CLA-mix); 2) cis9, trans11-CLA (c9,t11-CLA); or 3) control (olive oil) ... The CLA-mix group had less total FM (4%) and lower-body FM (7%) than the control (P = 0.02 and < 0.001, respectively). Post hoc analyses showed that serum insulin concentrations were greater in the CLA-mix group (34%) than the control group (P = 0.02) in the highest waist circumference tertile only ... In conclusion, a 50:50 mixture of c9,t11- and t10,c12-CLA isomers resulted in less total and lower-body FM in postmenopausal women and greater serum insulin concentrations in the highest waist circumference tertile" - See CLA products at iHerb.  As with all CLA studies, I wish they would state brand names instead of leaving it to the reader to figure out which mixture corresponds to which brand name.  I've seen studies where some isomers increase insulin sensitivity while others have the opposite effect.
  • Intravaginal dehydroepiandrosterone (Prasterone), the physiological and a highly efficient treatment of vaginal atrophy - Menopause. 2009 May 8 - "All three doses (0.25%, 0.5%, and 1.0%) of DHEA ovules applied daily intravaginally induced a highly significant beneficial change in the percentage of vaginal parabasal and superficial cells and pH as well as in the most bothersome symptom at 2 weeks. At the standard 12-week time interval, 0.5% DHEA caused a 45.9 +/- 5.31 (P < 0.0001 vs placebo) decrease in the percentage of parabasal cells, a 6.8 +/- 1.29% (P < 0.0001) increase in superficial cells, a 1.3 +/- 0.13 unit (P < 0.0001) decrease in vaginal pH, and a 1.5 +/- 0.14 score unit (P < 0.0001) decrease in the severity of the most bothersome symptom. Similar changes were seen on vaginal secretions, color, epithelial surface thickness, and epithelial integrity. Comparable effects were observed at the 0.25% and 1.0% DHEA doses ... Local Prasterone, through local androgen and estrogen formation, causes a rapid and efficient reversal of all the symptoms and signs of vaginal atrophy with no or minimal changes in serum steroids, which remain well within the normal postmenopausal range. This approach avoids the fear of systemic effects common to all presently available estrogen formulations and adds a novel physiological androgenic component to therapy"
  • Serum steroid levels during 12-week intravaginal dehydroepiandrosterone administration - Menopause. 2009 May 8 - "The present data show that local daily intravaginal DHEA administration at DHEA doses of 3.25-13 mg was able to rapidly and efficiently achieve correction of all the signs and symptoms of vaginal atrophy and improve sexual function and caused no or minimal changes in serum sex steroid levels, which all remain within the normal postmenopausal range, thus avoiding the risks of all estrogen formulations"
  • Efficacy and safety of low-dose regimens of conjugated estrogens cream administered vaginally - Menopause. 2009 May 8 - "At week 12, improvements in VMI with daily and twice-weekly use of low-dose CE cream (27.9% and 25.8%, respectively) were significantly greater compared with placebo (3.0% and 1.0%, respectively; P < 0.001). Improvements in vaginal pH with daily and twice-weekly CE cream (-1.6 for both) were also significantly greater relative to placebo (-0.4 and -0.3, respectively; P < 0.001). VMI and vaginal pH responses were sustained through 52 weeks. Both CE cream regimens significantly reduced most bothersome symptom scores compared with placebo (P </= 0.001), including those for dyspareunia (P </= 0.01). There was no report of endometrial hyperplasia or carcinoma. Adverse events occurred with similar frequency among the active and placebo groups during the double-blind phase"
  • Soybean Component Reduces Menopause Effects - Science Daily, 4/11/09
  • Effects of Hypericum perforatum (St. John's wort) on hot flashes and quality of life in perimenopausal women: a randomized pilot trial - Menopause. 2009 Feb 3 - "After 3 months of treatment, compared with the placebo group, women in the St. John's wort group reported significantly better menopause-specific quality of life (P = 0.01) and significantly fewer sleep problems (P = 0.05) ... Hypericum perforatum may improve quality of life in ways that are important to symptomatic perimenopausal women" - See Kira® (LI 160 extract) St. John's wort at iHerb.
  • Flaxseed combined with low-dose estrogen therapy preserves bone tissue in ovariectomized rats - Menopause. 2009 Jan 29 - "Flaxseed + low-dose estrogen therapy resulted in the highest bone mineral density and peak load at the lumbar vertebrae, with no effect on bone mineral density or strength in the tibia and femur. Flaxseed and flaxseed + low-dose estrogen therapy resulted in significantly higher relative levels of alpha-linolenic acid and eicosapentaenoic acid and lower levels of linoleic acid, arachidonic acid, and n-6/n-3 ratio in the lumbar vertebrae and tibia compared with all other groups" - See flax seed products at iHerb.
  • Omega-3 Fatty Acids Ease Depressive Symptoms Related To Menopause - Science Daily, 1/28/09 - "Their study, published in the February issue of The American Journal of Clinical Nutrition, presents the first evidence that omega-3 supplements are effective for treating common menopause-related mental health problems ... Test results before and after the eight-week period indicate that omega-3s significantly improved the condition of women suffering symptoms of psychological distress and mild depression ... Women with hot flashes also noted that their condition improved after consuming omega-3s. At baseline, the number of daily hot flashes was 2.8 and dropped by an average of 1.6 in the group taking omega-3s and by 0.5 in the control group" - See Mega Twin EPA at iHerb and Jarrow Max DHA at iHerb.
  • Too Much Body Fat Bad for Bones? - WebMD, 10/31/08 - "postmenopausal women with a higher proportion of body fat tend to have lower bone mineral content"
  • Pine bark extract may ease menstrual pains: study - Nutra USA, 6/20/08 - "Pycnogenol, 60 mg per day ... At the end of the study, Suzuki and co-workers found that, while women in the low pain group showed no benefits from pine bark supplementation, women with dysmenorrhea did significantly benefit. In addition to a reduction in the use of NSAIDs, a reduction in the number of painful days due to dysmenorrhea from 2.1 days before supplementation to 1.3 days during the third and fourth menstrual cycle" - See Pine Bark/Pycnogenol products at iHerb or OPC + 95 products at iHerb (some say the grape seed extract is the same without the patent markup).
  • Daidzein-rich isoflavone aglycones are potentially effective in reducing hot flashes in menopausal women - Menopause. 2007 Jul 18 - "DRI supplementation may be an effective and acceptable alternative to hormone treatment for menopausal hot flashes"
  • Daidzein-rich supplement shows menopause potential - Nutra USA, 1/11/08 - "The new study, led by George Blackburn, assigned the subjects to receive daily supplements of the daidzein-rich isoflavone-aglycone (DRI) supplement at a dose of either 40 or 60 milligrams, or placebo for 12 weeks ... At the end of the study, the researchers report that the number of hot flushes in the group receiving the lower dose was reduced by 52 per cent, while the women receiving the higher dose experienced a 51 per cent reduction in the number of hot flushes. The placebo group reported a 39 per cent reduction in hot flush frequency" - [Abstract]
  • Endocrine regulation of the course of menopause by oral melatonin: first case report - Menopause. 2007 Nov 8 - "The data obtained in this case report show that melatonin administration was able to delay the characteristic endocrine changes that occur during the course of menopause" - See melatonin products at iHerb.
  • Flaxseed May Ease Hot Flashes - WebMD, 8/30/07
  • Flaxseed Shows Potential To Reduce Hot Flashes - Science Daily, 8/29/07 - "The frequency of hot flashes decreased 50 percent over six weeks, and the overall hot flash score decreased an average 57 percent for the women who completed the trial. Participants also reported improvements in mood, joint or muscle pain, chills and sweating; which significantly improved their health-related quality of life" - See flax seed products at iHerb.
  • Flaxseed shows potential against hot flushes - Nutra USA, 8/29/07
  • Walking, Yoga May Enhance Quality of Life During Menopause - Doctor's Guide, 3/22/07
  • Isoflavone treatment for acute menopausal symptoms - Menopause. 2007 Feb 6 - "In women receiving 60 mg isoflavones daily, hot flashes and night sweats were reduced by 57% and 43%, respectively" - See Isoflavone products at iHerb.
  • A Natural Approach to Menopause - Life Extension Magazine, 4/06
  • Exercise Eases Menopause Symptoms - WebMD, 3/24/06
  • Supplements for Menopausal Symptoms (Soy and Red Clover Isoflavones, Black Cohosh, and Progesterone Cream) review - ConsumerLab.com, 8/2/05
  • Sizing Up Alternatives to Hormones - Intelihealth, 3/30/05
  • Menopause at 20? - Dr. Weil, 8/26/04
  • Diet, Exercise Help Menopausal Women - WebMD, 8/3/04
  • DHEA Relieves Postmenopausal Symptoms - Healthwell Exchange Daily News, 3/18/04 - "DHEA supplementation can increase hormone levels in postmenopausal women toward premenopausal levels. They further suggest that women’s quality of life may be improved by DHEA supplementation after menopause. The increases in estrogen, testosterone, and DHEA levels observed in this study were 20 to 45% less than those observed in studies using 50 mg of DHEA per day, leading some to suggest that 25 mg per day might be a safer amount to use as a supplement" - See iHerb or Vitacosticon DHEA products.
  • Soy + Melatonin: Slight Effect in Menopause - WebMD, 2/20/04
  • Low-Dose DHEA Increases Androgen, Estrogen Levels in Menopause - Medscape, 12/12/03 - "Testosterone and dihydrotestosterone plasma levels, and plasma E1 and E2 levels increased significantly and progressively in both groups ... Cortisol F plasma levels progressively decreased throughout the study. Both groups also experienced significantly reduced LH and FSH plasma levels. GH and IGF-1 levels significantly increased in both groups. Supplementation did not induce changes in endometrial thickness ... These data support and confirm that DHEA must be considered a valid compound and drug for [hormone therapy] in postmenopausal women and not just a 'dietary supplement" - See iHerb or Vitacosticon DHEA products.
  • Managing Menopause Naturally - Health Supplement Retailer, 10/03
  • Soy Protein May Be Better Than Supplements for Menopause - WebMD, 4/24/03
  • Grape Seed Extract May Be A Useful Supplement To Blunt Hypertension In Postmenopausal Women - Intelihealth, 4/10/03 - "a diet moderately high in grape seed extract can blunt salt (sodium chloride)-sensitive hypertension to about the same extent as treatment with either plant estrogens or 17ß-estradiol. This suggests that mechanisms other than the estrogen receptor activation actually provides the beneficial effects of estrogen therapy and that grape seed extract may be a useful supplement to blunt hypertension and other cardiovascular symptoms in postmenopausal women" - See iHerb or Vitacosticon grape seed extract products.
  • Postmenopausal Women May Need Supplements To Suppress Parathyroid Hormone Levels - Doctor's Guide, 12/20/02 - "These findings may call for widespread supplementation with calcium and vitamin D may be required in postmenopausal women"
  • Diet Rich In Soy Protein Lowers Estrogens Associated With Breast Cancer - Intelihealth, 9/24/02 - "Consuming tofu and other soy-based foods significantly lowers levels of a class of estrogens normally associated with breast cancer risk in postmenopausal women ... The study found a link between soy-rich diets consumed by Asian women in Singapore and reduced levels of an estrogen called estrone, the predominant form of estrogen in women following menopause ... estrone levels did not decline in a linear manner with increasing soy intake; an apparent reduction was only seen among those in the top 25 percent of soy protein consumers ... The study also showed that hormone levels remained unaffected by other dietary and lifestyle choices. These included consumption of alcohol, coffee, tea, fat, fiber and various micronutrients, including vitamins A, C and E, along with calcium and carotenoids ... There is a suggestion that weight change (particularly weight increase) has a profound influence on breast cancer rates in Asian-American women"
  • Back Exercises Reduce Risk of Vertebral Fracture Even After Exercises are Discontinued - Doctor's Guide, 9/23/02
  • Herbs, Supplements Offer Menopause Solutions - Natural Foods Merchandiser, 9/02
  • Herb Fights Menopause Symptoms - WebMD, 3/28/02 - "New research suggests that a black cohosh extract, marketed as Remifemin, works differently from estrogen, which has been linked to an increase in breast cancer risk ... As many as 80% will experience menopausal symptoms such as hot flashes, mood swings, night sweats, and bouts of insomnia ... These days, many different manufacturers market black cohosh supplements. But Remifemin is the only one that has been extensively studied"
  • Can Healthy Foods Replace Hormone Therapy? - Natural Foods Merchandiser, 10/01
  • Menopause Relief: From Burgers to Buttercups - WebMD, 7/23/01
  • Chaste Tree Bears Fruit for PMS Relief, Dried Fruit Extract Improves Symptoms in Half of Women Tested - WebMD, 1/19/01 - "A little more than half of the women who received the real Vitex reported improvements in five of six symptoms, including irritability, mood alteration, anger, headache, and breast fullness."
  • Sex . . . Power . . . and Health - Life Enhancement Magazine, 9/00 - "Whereas placebo did not alleviate any symptom in any member of the control group, Tribulus brought about some significant level of improvement in 98% (49 out of 50) of the women in the treatment group, including the alleviation of hot flashes, sweating, depression, insomnia, and anxiety. There were no significant changes in any measured hormone level, including FSH (follicle-stimulating hormone), LH (luteinizing hormone), prolactin, estradiol, progesterone, and testosterone. Tribulus was without significant side effects."
  • For Reducing Heart Disease Risk, Fish Oil Isn't Snake Oil - WebMD, 8/8/00
  • Postmenopausal Bone Loss Prevented With Low Dose HRT Plus Calcium - Doctor's Guide, 6/2/99
  • Menopause - Stopping The Symptoms Before They Stop You - Life Extension Magazine, 6/98

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