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Home > Anti-aging Research > Marijuana
Marijuana
News & Research:
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Cannabis Use Linked to
Early Age at Onset of Psychosis - Medscape, 9/11/08
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Smoking Cannabis May
Impair Function of Large Airways - Medscape, 8/1/08
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Schizophrenia Linked To Dysfunction In Molecular Brain Pathway Activated By
Marijuana - Science Daily, 7/7/08 - "The use of
marijuana in individuals with schizophrenia appears to worsen this deficit
in GABA synthesis"
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Oral
Cannabis Ineffective In Treating Acute Pain, Study Finds - Science
Daily, 6/24/08
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Cannabis 'can harm foetal brain' - BBC News, 6/16/08 -
"Smoking cannabis while pregnant could harm the
developing foetal brain ... the backbones of higher cognitive functions - do
not develop normally when endocannabinoid signalling is disturbed"
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Report: Marijuana potency rises - USATODAY.com, 6/12/08
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Marijuana Use May Shrink the Brain - WebMD, 6/2/08 -
"the hippocampus, which is thought to regulate
memory, was an average of 12% smaller among marijuana users, compared with
people who didn't smoke pot. The amygdala, involved in emotion and memory,
was an average of 7% smaller ... The study also suggests that long-term
marijuana users were more likely to report symptoms associated with mental
disorders"
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Long-term Cannabis Users May Have Structural Brain Abnormalities -
Science Daily, 6/2/08
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Marijuana Users Have Increased apoC3, Triglycerides - Medscape, 5/19/08
- "Heavy, chronic use of marijuana causes increased
levels of apolipoprotein C3 (apoC3), which in turn results in a major
increase in triglyceride levels"
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Take this Marijuana Message to Heart - WebMD, 5/13/08 -
"the active chemical in marijuana, THC, causes the
body to overproduce a protein called ApoC-111. ApoC-111 is linked to high
triglycerides (blood fats) because of problems with the breakdown of blood
fats in the body"
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Feds: Teen Use of Pot Can Lead to Dependency, Mental Illness -
Intelihealth, 5/12/08
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White House Warns of Pot-Depression Link - WebMD, 5/9/08
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Teen Marijuana Use Linked to Later Illness - washingtonpost.com, 5/8/08
- "Teenagers who smoke marijuana put themselves at
risk for future mental illness and higher rates of depression ... studies
show links between marijuana use and risk of mental illness later in life,
and that use could increase the risk by as much as 40 percent ... teenagers
who smoke marijuana at least once a month are three times more likely to
have suicidal thoughts than non-users"
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Withdrawal Symptoms From Smoking Pot? - WebMD, 5/7/08
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Smoke Pot, Get Lead Poisoning? - WebMD, 4/9/08
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Sex, Drugs, and Cancer? - WebMD, 3/11/08 - "Head
and neck cancers that were positive for HPV 16 were associated with having
more oral sex partners and smoking more marijuana ... Head and neck cancers
that were negative for HPV 16 weren't linked to sex or marijuana. Instead,
they were tied to smoking tobacco, drinking alcohol, and having poor oral
hygiene"
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Daily Cannabis Smoking
Linked With Increased Steatosis Severity - Medscape, 3/5/08
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Marijuana use
associated with increased risk of mortality among acute MI patients -
theheart.org, 3/5/08
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Marijuana, MI, and
Mortality - Medscape, 3/3/08
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Pot Use May Hamper Thinking in MS - WebMD, 2/13/08 -
"Marijuana smokers had slower average reaction times
on a test that challenged them to process information quickly. And they were
more likely to report a history of psychiatric diagnoses, most of which were
depression or anxiety diagnoses"
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Marijuana Linked to Early Gum Disease - WebMD, 2/5/08 -
"Compared with people who smoked no pot at all,
heavy marijuana users were three times more likely to have at least one gum
site with evidence of severe gum disease and 60% more likely to show
evidence of mild gum disease"
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Lung Cancer Risk Increases With Cannabis Use - oncologystat.com, 1/29/08
- "smoking a single joint is the same as smoking 20
cigarettes in terms of lung cancer risk ... cannabis smoke contains higher
levels of carcinogens than cigarette smoke ... cannabis smokers are more
likely to inhale more smoke deeply and hold it in their lungs longer,
allowing for more carcinogens to be deposited in the lungs. Marijuana
cigarettes do not usually have proper filters and are smoked to the tip,
which also increases the amount of smoke inhaled ... smoking 1 joint daily
for 10 years or 2 joints daily for 5 years increased the risk of lung cancer
5.7 times"
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Marijuana Withdrawal As Bad As Withdrawal From Cigarettes - Science
Daily, 1/25/08 - "overall withdrawal severity
associated with marijuana alone and tobacco alone was of similar frequency
and intensity. Sleep disturbance seemed to be more pronounced during
marijuana abstinence, while some of the general mood effects (anxiety,
anger) seemed to be greater during tobacco abstinence"
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Marijuana Smokers Face Rapid Lung Destruction -- As Much As 20 Years Ahead
Of Tobacco Smokers - Science Daily, 1/23/08 -
"the mean age of marijuana-smoking patients with lung problems was 41, as
opposed to the average age of 65 years for tobacco-smoking patients"
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Pot Slows Cancer in Test Tube - WebMD, 12/26/07 -
"The researchers are quick to point out that much
more study is needed to find out whether these test-tube results apply to
tumor growth in animals and in humans"
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Marijuana Smoke Contains Higher Levels Of Certain Toxins Than Tobacco Smoke
- Science Daily, 12/17/07 - "ammonia levels were 20
times higher in the marijuana smoke than in the tobacco smoke, while
hydrogen cyanide, nitric oxide and certain aromatic amines occurred at
levels 3-5 times higher in the marijuana smoke"
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Study Shows Toxins in Marijuana Smoke - WebMD, 12/14/07 -
"Ammonia levels were up to 20 times higher in
marijuana smoke than in tobacco smoke. Levels of hydrogen cyanide and
nitrogen-related chemicals were three to five times higher in marijuana
smoke than in tobacco smoke"
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Cannabis Smoking Contributes to Pulmonary Disease - Medscape, 12/13/07 -
"Cannabis smoking was associated with an increased
risk of wheeze, chest tightness, and cough ... Cannabis smokers had twice
the risk of chronic bronchitis and a 70% increased risk of asthma diagnosed
after age 16 years ... Cannabis and tobacco smoking were both associated
with a reduction in the FEV1/FVC ratio ... An increased percentage of low
density lung tissue was associated with cannabis smoking ... one joint was
pathologically equivalent to 2.5 to 5 tobacco cigarettes"
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Teens Who Smoke Marijuana But Not Tobacco Are Different From Other Teen
Groups - Science Daily, 11/5/07
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Too much cannabis
'worsens pain' - BBC News, 10/24/07
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Cannabis: Potent Anti-depressant In Low Doses, Worsens Depression At High
Doses - Science Daily, 10/23/07
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1 Joint Equals Up to 5 Cigarettes - Intelihealth, 8/1/07
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Smoking Pot May Damage Lungs - WebMD, 7/31/07
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Cannabis harm
worse than tobacco - BBC News, 7/30/07
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Are Smoking Pot and Psychosis Linked? - WebMD, 7/26/07
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Study: Marijuana may increase psychosis risk - USA Today, 7/26/07 -
"even infrequent use could raise the small but real
risk of this serious mental illness by 40% ... The scientists found a more
disturbing outlook for "heavy users" of pot, those who used it daily or
weekly: Their risk for psychosis jumped to a range of 50% to 200%"
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How Pot Harms Fetal Brain Development - WebMD, 5/24/07
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Marijuana Worsens COPD Symptoms In Current Cigarette Smokers - Science
Daily, 5/21/07
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Doctors: Pot Triggers Psychotic Symptoms - Intelihealth, 5/1/07
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Does Pot Triggers Psychotic Symptoms? - Time, 4/30/07
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Cannabis 'disrupts brain centre' - BBC News, 4/30/07 -
"those who took THC showed reduced
activity in an area of the brain called the inferior frontal cortex, which
keeps inappropriate thoughts and behaviour, such as swearing and paranoia in
check"
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Marijuana Cuts Lung Cancer Tumor Growth In Half, Study Shows - Science
Daily, 4/17/07
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Long-term Marijuana Smoking Leads To Respiratory Complaints - Science
Daily, 2/14/07
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Caution: Marijuana may not be lesser evil - USA Today, 2/5/07
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Cannabis 'affecting young minds' - BBC News, 12/10/06
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Why Marijuana May Affect Memory - WebMD, 11/20/06
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Marijuana Use Causes Early Pregnancy Failure - Science Daily, 8/4/06
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FDA OKs Return of 'Marijuana' Drug - WebMD, 5/18/06
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Marijuana-like Compounds Suppress The Immune Response - Science Daily,
4/26/06
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Smoking Marijuana May Dim Memory - WebMD, 3/13/06
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Marijuana Use, Schizophrenia Show Similar Patterns in Developing Adolescent
Brains - Doctor's Guide, 12/5/05
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Cannabis doubles fatal crash risk - BBC News, 12/2/05
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Cannabis increases car-crash risk - BBC News, 4/30/05
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More
Evidence Of Cannabis-induced Psychosis - Science Daily, 4/19/05
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Cannabis medicine 'causes harm' - BBC News, 4/1/05
- Drug 'doubles mental health risk' - BBC News, 3/1/05
- Regular Cannabis Use May Increase Risk Of Stroke - Doctor's Guide, 2/21/05
- Marijuana's Effects Linger in the Brain - WebMD, 2/7/05
- Marijuana Associated With Same Respiratory Symptoms as Tobacco - Doctor's Guide, 1/13/05
- Cannabis raises risk of psychosis - BBC News, 12/1/04
- Study Finds Cannabis Triggers Transient Schizophrenia-like Symptoms - Science Daily, 6/15/04
- Heavy, Long-Term Use of Cannabis Might Be Linked to Numerous Negative Features in American Users - Doctor's Guide, 1/2/04
- Portly Pot Puffers Beware - CBS News, 10/17/03
- Marijuana Smoking Doesn't Kill - WebMD, 9/18/03
- Marijuana Withdrawal Syndrome a Real Entity - Medscape, 8/8/03
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Prenatal Exposure to Marijuana Is Tied to Hearing Problems - Clinical Psychiatry News, 7/03
- Heavy Marijuana Use Doesn't Damage Brain - WebMD, 7/1/03
- Pot and Pregnancy: A Potent Mix? - Dr. Weil, 5/21/03
- Cannabis May Suppress Immune System - WebMD, 4/15/03
- Smoking Marijuana While Pregnant Could Have Lasting Effect on Fetus - WebMD, 3/25/03
- Twin Study Adds Fuel To Marijuana Debate - Psychiatric Times, 3/21/03 -
"Findings from a new study of more than 300 sets of twins show that early
use of marijuana, independent of genetic background and environment, is associated with later drug use and abuse"
- Synthetic Marijuana May Ease Depression - WebMD, 12/2/02
- Pot May Cause Depression, Schizophrenia - WebMD, 11/21/02
- Pot as Tough on Lungs as Tobacco - WebMD, 11/12/02
- Study of Marijuana to Treat Glaucoma Turns out to be a Bust - Doctor's Guide, 10/25/02
- Marijuana-Derived Compound Targets Pain, Inflammation - Intelihealth, 8/22/02
- Survey Of MS Patients Suggests Widespread Use of Cannabis for Pain and Symptom Relief - Doctor's Guide, 8/20/02
- Marijuana-Like Compound Banishes Fear - WebMD, 8/2/02
- Jury's Still Out On Use Of Marijuana Derivative For MS - Intelihealth, 5/14/02
- Marijuana's So-Called Gateway Effect - WebMD, 4/5/02
- Pot Lowers IQ - WebMD, 4/2/02
- Heavy Pot Use Impairs Brain Functioning - Intelihealth, 3/6/02
- Long-Term Pot Smokers Risk Brain Damage - WebMD, 3/5/02
- Link Between Cannabis Abuse And Depression Needs Further Investigation - Doctor's Guide, 1/2/02
- Marijuana-Linked Memory Problems Not Lasting - Doctor's Guide, 11/9/01
- Marijuana Withdrawal Similar To That of Nicotine - Doctor's Guide, 11/9/01
- Pot Is Part of a Heart Un-Healthy Lifestyle - WebMD, 6/15/01
- Marijuana Use May Trigger Acute CNS Infarction - Doctor's Guide, 3/4/01
- Heavy Pot Use Can Cause Physical Dependence - WebMD, 11/27/00
- Marijuana may be greater cancer risk than tobacco, research suggests - CNN, 6/21/00
- Regular Marijuana Use Could Lead to Emphysema - WebMD, 3/20/00
- More Evidence Shows Marijuana Is Addictive - Doctor's Guide, 6/9/98
- Effects of Long-Term Marijuana Use on the Brain Shown Similar To Other Addicting Drugs - Doctor's Guide, 6/27/97
- Marijuana Alters Immunity As Well As Mood, Researcher Says - Doctor's Guide, 6/9/97
Abstracts:
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Atrial fibrillation and marijuana smoking - Int J Clin Pract.
2007 Nov 21 - "Marijuana smoking affects the
circulatory system triggering various cardiovascular events. Of
note, recent case reports indicate a possible association with
atrial fibrillation (AF). In this article, we provide a brief
systematic review of all reported cases implicating marijuana
smoking in AF development and we concisely discuss the potential
underlying mechanisms as well as the clinical implications of this
emerging association"
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Cannabis and psychosis - Lancet. 2007 Nov 3;370(9598):1540
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Genetic effects of marijuana - Int J Addict.
1990-1991;25(1A):19-33 - "Marijuana and its
constitutive cannabinoids--tetrahydrocannabinol (THC), cannabinol
(CBN), and cannabidiol (CBD)--markedly affect mammalian cells.
Cytogenetic studies have revealed that cannabinoids induce
chromosome aberrations in both in vivo and in vitro studies. These
aberrations include chromosomal breaks, deletions, translocations,
errors in chromosomal segregation, and hypoploidy, and are due to
the clastogenic action of cannabinoids or to cannabinoid-induced
disruption of mitotic events or both. Conflicting reports of the
cytogenetic effects of cannabinoids are partially explained by the
different experimental protocols, cell types, and animals used by
investigators. Cannabinoids also suppress macromolecular synthesis
(DNA, RNA, and protein) as well as reduce the level of histone gene
expression. In general these studies show that cannabinoids are
detrimental to the health of an individual"
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Effects of administration of cannabis resin during pregnancy on
emotionality and learning in rats' offspring - Percept Mot
Skills. 1980 Apr;50(2):359-65 - "Injection
of cannabis resin as a saline-Tween 80 solution to pregnant rats
resulted in pups having lower body weight, higher emotionality,
poorer learning capacity, and paradoxically higher brain weight and
DNA content. The cannabis appeared directly to have caused the
inferior growth rate of the pups which in turn affected emotionality
and learning"
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