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Home > Anti-aging Research > Marijuana

Marijuana

News & Research:

Abstracts:

  • Cannabis Use, Ischemic Stroke, and Multifocal Intracranial Vasoconstriction: A Prospective Study in 48 Consecutive Young Patients - Stroke. 2011 Apr 21 - "Multifocal angiopathy associated with cannabis consumption could be an important cause of ischemic stroke in young people"
  • Cannabis Use and Earlier Onset of Psychosis: A Systematic Meta-analysis - Arch Gen Psychiatry. 2011 Feb 7
  • Early endothelial dysfunction as a marker of vasculogenic erectile dysfunction in young habitual cannabis users - Int J Impot Res. 2008 Nov-Dec;20(6):566-73 - "We conclude that early endothelial damage may be induced by chronic cannabis use (and endocannabinoid system activation); insulin resistance may be the hallmark of early endothelial dysfunction and may concur to determine vascular ED in the absence of obesity"
  • Atrial fibrillation and marijuana smoking - Int J Clin Pract. 2007 Nov 21 - "Marijuana smoking affects the circulatory system triggering various cardiovascular events. Of note, recent case reports indicate a possible association with atrial fibrillation (AF). In this article, we provide a brief systematic review of all reported cases implicating marijuana smoking in AF development and we concisely discuss the potential underlying mechanisms as well as the clinical implications of this emerging association"
  • Cannabis and psychosis - Lancet. 2007 Nov 3;370(9598):1540
  • Genetic effects of marijuana - Int J Addict. 1990-1991;25(1A):19-33 - "Marijuana and its constitutive cannabinoids--tetrahydrocannabinol (THC), cannabinol (CBN), and cannabidiol (CBD)--markedly affect mammalian cells. Cytogenetic studies have revealed that cannabinoids induce chromosome aberrations in both in vivo and in vitro studies. These aberrations include chromosomal breaks, deletions, translocations, errors in chromosomal segregation, and hypoploidy, and are due to the clastogenic action of cannabinoids or to cannabinoid-induced disruption of mitotic events or both. Conflicting reports of the cytogenetic effects of cannabinoids are partially explained by the different experimental protocols, cell types, and animals used by investigators. Cannabinoids also suppress macromolecular synthesis (DNA, RNA, and protein) as well as reduce the level of histone gene expression. In general these studies show that cannabinoids are detrimental to the health of an individual"
  • Effects of administration of cannabis resin during pregnancy on emotionality and learning in rats' offspring - Percept Mot Skills. 1980 Apr;50(2):359-65 - "Injection of cannabis resin as a saline-Tween 80 solution to pregnant rats resulted in pups having lower body weight, higher emotionality, poorer learning capacity, and paradoxically higher brain weight and DNA content. The cannabis appeared directly to have caused the inferior growth rate of the pups which in turn affected emotionality and learning"

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