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Anti-aging Research > HMB
News & Research:
Prevalence of and interventions for sarcopenia in ageing adults: a systematic
review. Report of the International Sarcopenia Initiative (EWGSOP and IWGS)
- oxfordjournals.org - 9/21/14 - "EAAs (with 2.5 g of leucine) and HMB seem to
have some effects on muscle mass and muscle function that need to be confirmed
in larger trials" - [Nutra
USA] - See
leucine products at Amazon.com
and Core Nutritionals Hmb Dietary Supplement, 90 Gram.
Supplements That Increase The Effects Of Resistance Exercise Identified
- Intelihealth, 3/19/03 -
"of the more than 250 dietary products available,
only HMB and creatine supplements have
sufficient scientific evidence showing that lean body mass and strength
gains accompanying resistance training are augmented with their use"
ACSM Conference Unveils Performance Enhancers - Nutrition Science News,
"(HMB) can increase strength and lean body mass ...
3 g/day HMB for four weeks ... Men in the HMB group lowered their LDL from
172 mg/dL to 123 mg/dL and increased their lean mass by 6 percent (35.3 to
37.68 kg) ... strength was significantly increased in all three tested
- HMB Pumps You Up
While Lowering Cholesterol and Blood Pressure - WebMD, 8/18/00 -
"These figures are just about what you would see by
taking medications for hypertension or lowering cholesterol."
- The effects of
phosphatidic acid supplementation on strength, body composition, muscular
endurance, power, agility, and vertical jump in resistance trained men -
J Int Soc Sports Nutr. 2016 Jun 2;13:24 - "Phosphatidic
acid (PA) is a lipid messenger that has been shown to increase muscle
protein synthesis via signaling stimulation of the mammalian target of
rapamycin (mTOR). MaxxTOR® (MT) is a supplement that contains PA as the main
active ingredient but also contains other synergistic mTOR signaling
substances including L-Leucine, Beta-Hydroxy-Beta-Methylbutyrate (HMB), and
Vitamin D3 ... participants were tested on one repetition maximum (1RM) leg
press strength (LP), 1RM bench press strength (BP), push-ups to failure
(PU), vertical jump (VJ), pro-agility shuttle time (AG), peak power output
(P), lean body mass (LBM), fat mass (FM), and thigh muscle mass (TMM) ...
There was a significant main effect (F(1,16) = 33.30, p < 0.001) for LBM
where MT significantly increased LBM when compared to the PLA group
(p < 0.001). Additionally, there was a significant main effect for LP
(F(1,16) = 666.74, p < 0.001) and BP (F(1,16) = 126.36, p < 0.001) where
both increased significantly more in MT than PLA group (p < 0.001). No
significant differences between MT and PLA were noted for FM, TMM, VJ, AG,
P, or PU"
USA] - Note: Seems like you might have gotten the same
results with l-leucine (one of the ingredients in MaxxTOR®) alone. See
phosphatidic acid at Amazon.com,
HMB at Amazon.com
leucine products at Amazon.com.
attenuates muscle loss during sustained energy deficit induced by calorie
restriction and endurance exercise - Metabolism. 2013 Jul 19 -
"Mice were divided into four groups (n=10/group): 1)
ALT=ad libitum+trained (1h/d for 3d/wk); 2) ALTH=ALT+HMB (0.5g/kg BW/d); 3)
C=calorie restricted (-30%)+trained (6h/d, 6d/wk); and 4) CH=C+HMB ... HMB
improves body composition and sensorimotor function during normal training
and attenuates muscle mass and strength loss during catabolic conditions"
Effect of β-hydroxy-β-methylbutyrate (HMB) on lean body mass during 10 days
of bed rest in older adults - Clin Nutr. 2013 Mar 4 -
"Loss of muscle mass due to prolonged bed rest decreases functional capacity
and increases hospital morbidity and mortality in older adults ... In
healthy older adults, HMB supplementation preserves muscle mass during 10
days of bed rest"
Creatine and beta-hydroxy-beta-methylbutyrate (HMB) additively increase lean
body mass and muscle strength during a weight-training program -
Nutrition 2001 Jul-Aug;17(7-8):558-66 - "In summary,
CR and HMB can increase LBM and strength, and the effects are additive"
Body Composition in 70-Year-Old Adults Responds to Dietary
beta-Hydroxy-beta-Methylbutyrate Similarly to That of Young Adults - J
Nutr 2001 Jul;131(7):2049-52 - "In conclusion,
changes in body composition can be accomplished in 70-y-old adults
participating in a strength training program, as previously demonstrated in
young adults, when HMB is supplemented daily"
Beta-hydroxy-beta-methylbutyrate (HMB) supplementation in humans is safe and
may decrease cardiovascular risk factors - J Nutr. 2000
"In conclusion, the objective data collected across
nine experiments indicate that HMB can be taken safely as an ergogenic aid
for exercise and that objective measures of health and perception of
well-being are generally enhanced."
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