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Home > Anti-aging Research > Ghrelin

Ghrelin

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  • Increased plasma PYY levels following supplementation with the functional fiber PolyGlycopleX in healthy adults - Eur J Clin Nutr. 2010 Jul 28 - "A variety of dietary fibers have been shown to alter satiety hormone gene expression and secretion. The objective of this study was to examine plasma satiety hormone concentrations in healthy subjects consuming either PolyGlycopleX (PGX) or control (skim milk powder) for 21 days ... Primary outcomes measured at three visits (V1, V2 and V3) were plasma active glucagon-like peptide-1 (GLP-1) total ghrelin, peptide YY (PYY) and insulin. Results: There was a significant effect of visit for fasting PYY with control participants experiencing decreased PYY levels over time while PGX prevented this decline. When stratified by body mass index (BMI), PGX increased fasting PYY levels from week 1 to week 3 compared with control in participants with BMI <23 kg/m(2). There was a significant effect of visit for fasting ghrelin with levels decreasing in both PGX and control groups over time. No differences were detected in fasting GLP-1 levels. Although there was a 14% reduction in fasting insulin between V1 and V3 with PGX this was not significantly different from control" - Note:  I don't know how they determine that a 14% reduction isn't significant.  See PGX™ products at iHerb.
  • Exercise Suppresses Appetite By Affecting Appetite Hormones - Science Daily, 12/19/08 - "A vigorous 60-minute workout on a treadmill affects the release of two key appetite hormones, ghrelin and peptide YY, while 90 minutes of weight lifting affects the level of only ghrelin"
  • What makes people fat, why diets don't work, and what triggers appetite? - Dr. Murray's Natural Facts, 3/17/04 - "preliminary evidence indicates that PGX™ has powerful effects on reducing regulatory compounds that stimulate appetite like ghrellin while at the same time increasing the levels of regulatory compounds that block the appetite like PYY, CCK, and adiponectin. Further studies being conducted by Dr. Vuksan will likely show that PGX™ exerts powerful effects on these appetite regulators" - See iHerb or Vitacosticon PGX products.

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