|
|
|
Welcome to the Quality Counts. For those health conscious consumers and medical professionals that are looking to purchase nutritional supplements, vitamins, herbs, learning about medications, losing weight, health food, low carbs, high protein nutrition, and exercise, you have come to the right place. Quality Counts serves both the medical practitioner and consumer interested in nutritional therapy and alternative medicine.
Home >
Anti-aging Research > Fructose
Fructose
News & Research:
-
High
fizzy soft drink consumption linked to violence among teens - Science
Daily, 10/25/11 - "heavy use of carbonated non-diet
soft drinks was significantly associated with carrying a gun or knife, and
violence towards peers, family members and partners ... When the findings
were divided into four categories of consumption, the results showed a clear
dose-response relationship across all four measures ... There may be a
direct cause-and-effect-relationship, perhaps due to the sugar or caffeine
content of soft drinks, or there may be other factors, unaccounted for in
our analyses, that cause both high soft drink consumption and aggression"
-
Dietary Fructose
and Risk of Metabolic Syndrome in Adults - Medscape, 9/28/11 -
"in our study the association between dietary
fructose and metabolic syndrome and its components was observed only in the
third and fourth quartiles of fructose intakes, approximately over 8 and 12%
of energy intake (> 50 g/d); while dietary intake of fructose from natural
sources including fruits and vegetables, even in the fourth quartile of
fructose intakes was only 5% of energy, approximately 30 g/d. Thus, the
increased risk of metabolic syndrome and its components may be attributed to
increase fructose intake from industrialized foods"
-
Sugar-sweetened drinks associated with higher blood pressure - Science
Daily, 3/1/11 - "for every extra sugar-sweetened
beverage drunk per day participants on average had significantly higher
systolic blood pressure by 1.6 millimeters of mercury (mm Hg) and diastolic
blood pressure higher by 0.8 mm Hg ... They found no consistent association
between diet soda intake and blood pressure levels. Those who drank diet
soda had higher mean BMI than those who did not and lower levels of physical
activity ... One possible mechanism for sugar-sweetened beverages and
fructose increasing blood pressure levels is a resultant increase in the
level of uric acid in the blood that may in turn lower the nitric oxide
required to keep the blood vessels dilated. Sugar consumption also has been
linked to enhanced sympathetic nervous system activity and sodium retention"
-
Highest Mortality Risk Seen With High-Fat Dairy and High Sugar Intake -
Medscape, 12/23/10 - "Compared to people who ate
healthy foods, men and women in their 70s had a 40% higher risk of death if
they got most of their calories from high-fat dairy foods or from sweets and
desserts" - I'd take that one study with a grain of salt. In
regard to dairy, it contradicts this analysis of many studies.
-
Milk and dairy
consumption and incidence of cardiovascular diseases and all-cause
mortality: dose-response meta-analysis of prospective cohort studies
- Am J Clin Nutr. 2011 Jan;93(1):158-71 - "PubMed,
EMBASE, and SCOPUS were searched for articles published up to February
2010. Of >5000 titles evaluated, 17 met the inclusion criteria, all of
which were original prospective cohort studies ... A modest inverse
association was found between milk intake and risk of overall CVD [4
studies; relative risk (RR): 0.94 per 200 mL/d; 95% CI: 0.89, 0.99].
Milk intake was not associated with risk of CHD (6 studies; RR: 1.00;
95% CI: 0.96, 1.04), stroke (6 studies; RR: 0.87; 95% CI: 0.72, 1.05),
or total mortality (8 studies; RR per 200 mL/d: 0.99; 95% CI: 0.95,
1.03). Limited studies of the association of total dairy products and of
total high-fat and total low-fat dairy products (per 200 g/d) with CHD
showed no significant associations"
-
Excess fructose may play role in diabetes, obesity and other health
conditions - Science Daily, 11/22/10 - "The link
between excessive intake of fructose and metabolic syndrome is becoming
increasingly established. However, in this review of the literature, the
authors conclude that there is also increasing evidence that fructose may
play a role in hypertension and renal disease. "Science shows us there is a
potentially negative impact of excessive amounts of sugar and high fructose
corn syrup on cardiovascular and kidney health," explains Dr. Johnson. He
continues that "excessive fructose intake could be viewed as an increasingly
risky food and beverage additive.""
-
Fructose-rich beverages associated with increased risk of gout in women
- Science Daily, 11/10/10 - "Compared with
consumption of less than 1 serving per month, women who consumed one serving
per day had a 74 percent increased risk of gout; and those with 2 or more
servings per day had a 2.4 times higher risk ... Orange juice intake was
also associated with risk of gout. Compared with women who consumed less
than a glass (6 oz.) of orange juice per month, women who consumed 1 serving
per day had a 41 percent higher risk of gout, and there was a 2.4 times
higher risk with 2 or more servings per day"
-
Pancreatic cancers use fructose, common in the Western diet, to fuel their
growth - Science Daily, 8/2/10 - "The bottom
line is the modern diet contains a lot of refined sugar including fructose
and it's a hidden danger implicated in a lot of modern diseases, such as
obesity, diabetes and fatty liver ... the pancreatic cancer cells could
easily distinguish between glucose and fructose even though they are very
similar structurally, and contrary to conventional wisdom, the cancer cells
metabolized the sugars in very different ways. In the case of fructose, the
pancreatic cancer cells used the sugar in the transketolase-driven
non-oxidative pentose phosphate pathway to generate nucleic acids, the
building blocks of RNA and DNA, which the cancer cells need to divide and
proliferate"
-
High
fructose diet may contribute to high blood pressure, study finds -
Science Daily, 7/1/10 - "people who consumed a diet
of 74 grams or more per day of fructose (corresponding to 2.5 sugary soft
drinks per day) had a 26%, 30%, and 77% higher risk for blood pressure
levels of 135/85, 140/90, and 160/100 mmHg, respectively. (A normal blood
pressure reading is below 120/80 mmHg.)"
-
High
fructose, trans fats lead to significant liver disease, says study -
Science Daily, 6/22/10 - "mice fed the normal
calorie chow diet remained lean and did not have fatty liver disease. Mice
fed high calorie diets (trans-fat alone or a combination of trans-fat and
high fructose) became obese and had fatty liver disease ... it was only the
group fed the combination of trans-fat and high fructose which developed the
advanced fatty liver disease which had fibrosis ... This same group also had
increased oxidative stress in the liver, increased inflammatory cells, and
increased levels of plasma oxidative stress markers"
-
Fructose
sugar makes maturing human fat cells fatter, less insulin-sensitive, study finds
- Science Daily, 6/21/10 - "high levels of fructose, which may result from
eating a diet high in fructose, throughout childhood may lead to an increase in
visceral [abdominal] obesity, which is associated with increased cardiometabolic
risk ... For both types of fat cells, maturation in fructose decreased the
cells' insulin sensitivity, which is the ability to successfully take up glucose
from the bloodstream into fat and muscles. Decreased insulin sensitivity is a
characteristic of Type 2 diabetes"
-
Drinking fewer sugar-sweetened beverages may lower blood pressure -
Science Daily, 5/24/10 - ""Our findings suggest that
reducing sugar-sweetened beverages and sugar consumption may be an important
dietary strategy to lower blood pressure and further reduce other blood
pressure-related diseases," Chen said. "It has been estimated that a
3-millimeters of mercury (mm Hg) reduction in systolic blood pressure should
reduce stroke mortality by 8 percent and coronary heart disease mortality by
5 percent. Such reductions in systolic blood pressure would be anticipated
by reducing sugar-sweetened beverages consumption by an average of 2
servings per day ... a reduction of one serving/day of SSB was associated
with a 1.8 millimeters of mercury (mm Hg) drop in systolic pressure and a
1.1 mm Hg decline in diastolic pressure over 18 months"
-
Study: Too Much Sugar Increases Heart Risks - Time Magazine, 4/21/10 -
"Compared with people consuming less than 5% of
their daily calories in added sugar, those in the highest consumption group
— who got 25% or more of their daily calories in added sugar — were twice as
likely to have low levels of HDL cholesterol, the beneficial lipid that mops
up artery-clogging LDL cholesterol. According to government health
guidelines, HDL levels below 50 mg/dL for women and 40 mg/dL for men are
considered low; 43% of the highest sugar consumers recorded low HDL, while
only 22% of the lowest sugar consumers did ... People eating the most added
sugar also recorded the highest triglyceride levels ... Low HDL and high
triglyceride levels are two of the primary risk factors for heart disease"
-
High
fructose corn syrup linked to liver scarring, research suggests -
Science Daily, 3/22/10 - "The researchers found only
19 percent of adults with NAFLD reported no intake of fructose-containing
beverages, while 52 percent consumed between one and six servings a week and
29 percent consumed fructose-containing beverages on a daily basis"
-
High-fructose corn syrup prompts considerably more weight gain, researchers
find - Science Daily, 3/22/10
-
Drinking sugar-sweetened beverages daily linked to diabetes - Science
Daily, 3/6/10 - "Using the Coronary Heart Disease
(CHD) Policy Model, a well-established computer simulation model of the
national population age 35 and older, researchers estimate that the
increased consumption of sugar-sweetened beverages between 1990 and 2000
contributed to 130,000 new cases of diabetes, 14,000 new cases of coronary
heart disease (CHD), and 50,000 additional life-years burdened by coronary
heart disease over the past decade"
-
Soft
drink consumption may markedly increase risk of pancreatic cancer -
Science Daily, 2/8/10 - "Consuming two or more soft
drinks per week increased the risk of developing pancreatic cancer by nearly
twofold compared to individuals who did not consume soft drinks" -
[Abstract]
-
High
Fructose Intake Linked to Metabolic Syndrome, Kidney Disease - Science
Daily, 1/14/10 - "men who were randomized to receive
200 g fructose daily for 2 weeks without or without allopurinol ... Fructose
intake was associated with an average increase in systolic and diastolic
blood pressure of 7 and 5 mm Hg, respectively ... Mean fasting triglyceride
levels rose by 0.62 mmol/L (p < 0.002), while high-density lipoprotein
cholesterol levels fell by 0.06 mmol/L ... the prevalence of metabolic
syndrome increased by 25% to 33%"
-
Sugary cola drinks linked to higher risk of gestational diabetes -
Science Daily, 11/30/09
-
High
Fructose Corn Syrup: A Recipe For Hypertension, Study Finds - Science
Daily, 11/10/09 - "people who ate or drank more than
74 grams per day of fructose (2.5 sugary soft drinks per day) increased
their risk of developing hypertension. Specifically, a diet of more than 74
grams per day of fructose led to a 28%, 36%, and 87% higher risk for blood
pressure levels of 135/85, 140/90, and 160/100 mmHg, respectively. (A normal
blood pressure reading is below 120/80 mmHg.)"
-
High Fructose Intake May Raise Blood Pressure - WebMD, 11/2/09 -
"About 2.5 sugary soft drinks a day is enough to
elevate the pressure ... Overall, intakes of 74 grams or more daily was
associated with a 36% higher risk of having blood pressure of 140/90 or
higher, she found. Ideally, blood pressure should be below 120/80 ... ''We
know that fructose has the potential to reduce nitric oxide production
within the blood vessels,'' she says. "Nitric oxide relaxes the vessel and
is supposed to lower blood pressure. Fructose reduces the production of
nitric oxide and makes it difficult for the vessels to relax and dilate."
... Fructose also raises uric acid in the blood, she says, and that could
raise blood pressure. "Fructose can tell the kidneys to 'hold onto' more
salt, and that can contribute to high blood pressure,""
-
Health Buzz: Fructose-Heavy Diet Linked to Hypertension and Other Health
News - US News and World Report, 9/24/09 - "A
small study is among the first to show that regular consumption of
fructose-heavy foods and drinks might raise blood pressure—at least in men"
-
Heat
Forms Potentially Harmful Substance In High-fructose Corn Syrup -
Science Daily, 8/26/09
-
Eating
High Levels Of Fructose Impairs Memory In Rats - Science Daily, 7/16/09 -
"What we discovered is that the fructose diet doesn't affect their ability to
learn ... But they can't seem to remember as well where the platform was when
you take it away. They swam more randomly than rats fed a control diet"
-
Fructose-Sweetened Beverages Linked to Heart Risks - NYTimes.com,
4/23/09 - "a controlled and randomized study has
found that drinks sweetened with fructose led to higher blood levels of
L.D.L, or "bad" cholesterol, and triglycerides in overweight test subjects,
while drinks sweetened with another sugar, glucose, did not. Both L.D.L. and
triglycerides have been linked to an increased risk of cardiovascular
disease"
-
Fresh Take on Fructose vs. Glucose - WebMD, 4/21/09 -
"Both the groups gained weight during the trial, but
imaging studies revealed that most of the added fat in the fructose group
occurred in the belly, while most of the fat gained by the glucose group was
subcutaneous (under the skin) ... Belly fat, but not subcutaneous fat, has
been linked to an increased risk for heart disease and diabetes ... The
fructose group had higher total cholesterol and LDL "bad" cholesterol, plus
greater insulin resistance, which are consistent with metabolic syndrome,
while the glucose group did not"
-
High fructose corn syrup: How
dangerous is it? - MSNBC, 4/17/09
-
Fructose Metabolism By The Brain Increases Food Intake And Obesity, Review
Suggests - Science Daily, 3/25/09
-
Not
So Sweet: Over-consumption Of Sugar Linked To Aging - Science Daily,
3/9/09 - "We know that lifespan can be extended in
animals by restricting calories such as sugar intake ...it's not sugar
itself that is important in this process but the ability of cells to sense
its presence ... the lifespan of yeast cells increased when glucose was
decreased from their diet. They then asked whether the increase in lifespan
was due to cells decreasing their ability to produce energy or to the
decrease in signal to the cells by the glucose sensor ... cells unable to
consume glucose as energy source are still sensitive to the pro-aging
effects of glucose. Conversely, obliterating the sensor that measures the
levels of glucose significantly increased lifespan"
-
Why
Diets High In High-fructose Corn Syrup (found In Soda And Processed Foods)
Can Lead To Insulin Resistance - Science Daily, 3/3/09 -
"mice on a high-fructose diet were protected from
insulin resistance when a gene known as transcriptional coactivator PPARg
coactivator-1b (PGC-1b) was "knocked down" in the animals' liver and fat
tissue ... Fructose is much more readily metabolized to fat in the liver
than glucose is and in the process can lead to nonalcoholic fatty liver
disease ... NAFLD in turn leads to hepatic insulin resistance and type II
diabetes"
-
Fructose-sweetened Drinks Increase Nonfasting Triglycerides In Obese Adults
- Science Daily, 2/12/09 - "Obese people who drink
fructose-sweetened beverages with their meals have an increased rise of
triglycerides following the meal ... Increased triglycerides after a meal
are known predictors of cardiovascular disease"
-
Mercury in Some High Fructose Corn Syrup? - WebMD, 1/27/09 -
"we found detectable mercury in 17 of 55 samples, or
around 31%"
-
High-Fructose Corn Syrup’s Bad Rap Unfair? - WebMD, 12/11/08
-
Fructose Metabolism More Complicated Than Was Thought - Science Daily,
12/9/08
-
New data: High-fructose corn syrup no worse than sugar - USATODAY.com,
12/8/08 - "Now, the tide of research, if not public
opinion, has shifted. This week, five papers published in a supplement to
Clinical Nutrition find no special link between consumption of high-fructose
corn syrup and obesity ... It doesn't appear that when you consume
high-fructose corn syrup, you have any different total effect on appetite
than if you consume any other sugar"
-
Fructose -- Found In High-fructose Corn Syrup, Sugar -- Sets Table For
Weight Gain Without Warning - Science Daily, 10/16/08 -
"Eating too much fructose can induce leptin
resistance, a condition that can easily lead to becoming overweight when
combined with a high-fat, high-calorie diet"
-
High Fructose Corn Syrup: Too Sweet to Eat? - Dr. Weil, 9/1/08
-
Fructose May Make You Fatter - WebMD, 7/31/08 -
"Fructose gets made into fat more quickly, and when that process is turned
on there seems to be a signal that goes to the liver that says store all the
other fats you are seeing"
-
Limiting Fructose May Boost Weight Loss, Researcher Reports - Science
Daily, 7/24/08 - "One of the reasons people on
low-carbohydrate diets may lose weight is that they reduce their intake of
fructose, a type of sugar that can be made into body fat quick ... Fructose,
on the other hand, enters this metabolic pathway downstream, bypassing the
traffic cop and flooding the metabolic pathway"
-
High Fructose Corn Syrup Gets Unlikely Ally - WebMD, 6/18/08 -
"At a meeting in Chicago, AMA delegates backed a
resolution that argues that there's no scientific proof that high fructose
corn syrup deserves the blame for obesity more than sugar or other caloric
sweeteners. The resolution also nixes putting warning labels on products
containing high fructose corn syrup"
-
Sweet Soft Drinks,
Fructose Linked to Increased Risk for Gout - Medscape, 2/4/08
-
Blame
Sweet Soda for Gout? - WebMD, 1/31/08 -
"Compared with men who almost never drank sugar-sweetened soft drinks --
fewer than one per month -- frequent soft-drink drinkers were significantly
more likely to suffer gout: ... Two or more soft drinks each day upped gout
risk by 85% ... One soft drink each day upped gout risk by 45% ... Five or
six soft drinks each week upped gout risk by 29%"
-
Too
Much Fructose Could Leave Dieters Sugar Shocked - Science Daily,
12/13/07 - "Eating too much fructose causes uric
acid levels to spike, which can block the ability of insulin to regulate how
body cells use and store sugar and other nutrients for energy, leading to
obesity, metabolic syndrome and type 2 diabetes"
-
Too
Much Sugar Turns Off Gene That Controls Effects Of Sex Steroids -
Science Daily, 11/21/07 - "This discovery reinforces
public health advice to eat complex carbohydrates and avoid sugar ...
Glucose and fructose are metabolized in the liver. When there’s too much
sugar in the diet, the liver converts it to lipid. Using a mouse model and
human liver cell cultures, the scientists discovered that the increased
production of lipid shut down a gene called SHBG (sex hormone binding
globulin), reducing the amount of SHBG protein in the blood. SHBG protein
plays a key role in controlling the amount of testosterone and estrogen
that’s available throughout the body"
-
Sugary Drinks, Not Fruit Juice, May Be Linked To Insulin - Science
Daily, 9/5/07 - "Study participants who consumed two
or more sugar-sweetened beverages per day had significantly higher fasting
blood levels of insulin as compared to participants who did not report
consuming any such beverages, regardless of age, sex, weight, smoking
status, or other dietary habits ... Higher fasting levels of insulin mean
these study participants are more at risk for developing Type 2 diabetes ...
consumption of 100 percent fruit juice was not significantly related to any
of our measures of insulin resistance"
-
Soda
Warning? High-fructose Corn Syrup Linked To Diabetes, New Study Suggests
- Science Daily, 8/23/07 - "high-fructose corn syrup
(HFCS) ... Chi-Tang Ho, Ph.D., conducted chemical tests among 11 different
carbonated soft drinks containing HFCS. He found 'astonishingly high' levels
of reactive carbonyls in those beverages. These undesirable and
highly-reactive compounds associated with "unbound" fructose and glucose
molecules are believed to cause tissue damage ... Ho estimates that a single
can of soda contains about five times the concentration of reactive
carbonyls than the concentration found in the blood of an adult person with
diabetes ... adding epigallocatechin gallate (EGCG), a compound in tea,
significantly reduced the levels of reactive carbonyl species in a
dose-dependent manner when added to the carbonated soft drinks studied. In
some cases, the levels of reactive carbonyls were reduced by half"
-
Not
Enough Evidence To Indict High Fructose Corn Syrup In Obesity - Science
Daily, 7/27/07
-
Fructose: Sugar's Dark Side? - WebMD, 6/25/07
-
Fructose-Sweetened Drinks Tougher on Arteries - washingtonpost.com,
6/23/07 - "Fructose-sweetened drinks are more likely
to provoke the development of fatty artery deposits in overweight adults
than glucose-sweetened beverages ... Those who drank fructose-sweetened
drinks also had a boost in fasting blood concentrations of LDL ("bad")
cholesterol and other measures. Those levels were unaltered in those
consuming glucose-sweetened drinks, however"
-
Fructose-sweetened Beverages Increases Risk Of Obesity In Rats - Science
Daily, 3/16/07
-
Fructose-sweetened Beverages Increases Risk Of Diabetes In Rats -
Science Daily, 3/15/07
-
Sugar intake may hurt liver - Reuters, 10/31/06 -
"fatty liver disease was more common
in the group given sugar water, especially when exposed to a type of sugar
called fructose ... These data support the hypothesis that high fructose
consumption may not only (damage) the liver through over-feeding, but may be
directly" toxic"
-
Obesity and Fatty Liver disease - MedicineNet.com -
"Doctors also are using
medications to treat non alcoholic fatty liver disease. For example,
insulin-sensitizing agents, such as the thiazolidinediones,
pioglitazone (Actos)
and rosiglitazone
(Avandia), and metformin (Glucophage) not
only help to control blood glucose in patients with diabetes, but they
also improve enzyme levels in patients with non alcoholic fatty liver
disease"
- See pioglitazone or rosiglitazone at
OffshoreRx.com
 ,
XlPharmacy
or
SuperSaverMeds.com.
-
Avandia Positively Impacts On Factors Linked With Insulin Resistance
- Doctor's Guide, 9/18/00 - "Increased deposits of fat around the internal organs and in the liver
are commonly associated with insulin resistance and are found in many
type 2 diabetes patients ... Avandia helps prevent accumulation of fat
around the internal organs and significantly reduces hepatic fat"
-
Is Fructose Dangerous? -
thenutritionreporter.com
Abstracts:
-
COFFEE,
TEA AND SUGAR-SWEETENED CARBONATED SOFT DRINK INTAKE AND PANCREATIC CANCER
RISK: A POOLED ANALYSIS OF 14 COHORT STUDIES - Cancer Epidemiol
Biomarkers Prev. 2011 Dec 22 - "Sugar-sweetened
carbonated soft drink (abbreviated as SSB) intake has been associated with
higher circulating levels of insulin, which may promote carcinogenesis. Few
prospective studies have examined SSB intake and pancreatic cancer risk;
results have been heterogeneous ... pooled analysis from 14 prospective
cohort studies ... No statistically significant associations were observed
between pancreatic cancer risk and intake of coffee (MVRR=1.10, 95%
CI=0.81-1.48 comparing >900 to <0g/day; 237g≈8oz), tea (MVRR=0.96, 95%
CI=0.78-1.16 comparing >400 to 0g/day; 237g≈8oz) or SSB (MVRR=1.19, 95%
CI=0.98-1.46 comparing >250 to 0g/day; 355g≈12oz) (p-value, test for
between-studies heterogeneity >0.05). These associations were consistent
across levels of sex, smoking status and body mass index. When modeled as a
continuous variable, a positive association was evident for SSB (MVRR=1.06,
95% CI=1.02-1.12)"
-
Consumption of Fructose and High Fructose Corn Syrup Increase Postprandial
Triglycerides, LDL-Cholesterol, and Apolipoprotein-B in Young Men and Women
- J Clin Endocrinol Metab. 2011 Aug 17 - "The
American Heart Association Nutrition Committee recommends women and men
consume no more than 100 and 150 kcal of added sugar per day, respectively,
whereas the Dietary Guidelines for Americans, 2010, suggests a maximal added
sugar intake of 25% or less of total energy ... To address this discrepancy,
we compared the effects of consuming glucose, fructose, or high-fructose
corn syrup (HFCS) at 25% of energy requirements (E) on risk factors for
cardiovascular disease ... Twenty-four-hour triglyceride area under the
curve was increased compared with baseline during consumption of fructose
(+4.7 ± 1.2 mmol/liter × 24 h, P = 0.0032) and HFCS (+1.8 ± 1.4 mmol/liter ×
24 h, P = 0.035) but not glucose (-1.9 ± 0.9 mmol/liter × 24 h, P = 0.14).
Fasting LDL and apoB concentrations were increased during consumption of
fructose (LDL: +0.29 ± 0.082 mmol/liter, P = 0.0023; apoB: +0.093 ± 0.022
g/liter, P = 0.0005) and HFCS (LDL: +0.42 ± 0.11 mmol/liter, P < 0.0001;
apoB: +0.12 ± 0.031 g/liter, P < 0.0001) but not glucose (LDL: +0.012 ±
0.071 mmol/liter, P = 0.86; apoB: +0.0097 ± 0.019 g/liter, P = 0.90).
Conclusions: Consumption of HFCS-sweetened beverages for 2 wk at 25% E
increased risk factors for cardiovascular disease comparably with fructose
and more than glucose in young adults"
-
Sucrose,
high-sugar foods and risk of endometrial cancer - a population-based cohort
study - Cancer Epidemiol Biomarkers Prev. 2011 Jul 15 -
"During 18.4 years of follow-up, 729 participants
were diagnosed with incident endometrial cancer. Total sucrose intake and
consumption of sweet buns and cookies was associated with increased risk of
endometrial cancer. RRs (with 95% CIs) for consuming more than 35 grams of
sucrose/day and consuming sweet buns and cookies more than 3 times/week were
1.36 (1.04-1.77) and 1.42 (1.15-1.75) as compared to less than 15 grams of
sucrose/day and consuming sweet buns and cookies less than 0.5 times/week,
respectively. RRs for consuming more than 15 grams of sucrose/day as
compared to 15 grams or less were 1.97 (1.27-3.04) among obese women and
1.56 (1.20-2.04) among women with low fat intake"
-
Habitual
sugar intake and cognitive function among middle-aged and older Puerto
Ricans without diabetes - Br J Nutr. 2011 Jun 1:1-10 -
"Intake of added sugars, mainly fructose and
sucrose, has been associated with risk factors for cognitive impairment,
such as obesity, the metabolic syndrome and type 2 diabetes. The objective
of this analysis was to examine whether habitual intakes of total sugars,
added sugars, sugar-sweetened beverages or sweetened solid foods are
associated with cognitive function. The present study included 737
participants without diabetes, aged 45-75 years, from the Boston Puerto
Rican Health Study, 2004-9. Cognitive function was measured with a battery
of seven tests: Mini-Mental State Examination (MMSE), word list learning,
digit span, clock drawing, figure copying, and Stroop and verbal fluency
tests. Usual dietary intake was assessed with a validated FFQ. Greater
intakes of total sugars, added sugars and sugar-sweetened beverages, but not
of sugar-sweetened solid foods, were significantly associated with lower
MMSE score, after adjusting for covariates. Adjusted OR for cognitive
impairment (MMSE score < 24) were 2.23 (95 % CI 1.24, 3.99) for total sugars
and 2.28 (95 % CI 1.26, 4.14) for added sugars, comparing the highest with
lowest intake quintiles. Greater intake of total sugars was also
significantly associated with lower word list learning score. In conclusion,
higher sugar intake appears to be associated with lower cognitive function,
but longitudinal studies are needed to clarify the direction of causality"
-
Exercise
counteracts fatty liver disease in rats fed on fructose-rich diet -
Lipids Health Dis. 2010 Oct 14;9(1):116 - "The
fructose-fed rats showed decreased insulin sensitivity, and the
late-exercise training protocol counteracted this alteration. There was no
difference between the groups in levels of serum ALT, whereas AST and liver
lipids increased in the fructose-fed sedentary group when compared with the
other groups. Serum triglycerides concentrations were higher in the
fructose-fed trained groups when compared with the corresponding control
group"
-
Sugar
Sweetened Beverages and Risk of Metabolic Syndrome and Type 2 Diabetes: A
Meta-analysis - Diabetes Care. 2010 Aug -
"sugar-sweetened beverages (SSBs), which include soft drinks, fruit drinks,
iced tea, energy and vitamin water drinks ... Based on data from these
studies, including 310,819 participants and 15,043 cases of T2DM,
individuals in the highest quantile of SSB intake (most often 1-2
servings/day) had a 26% greater risk of developing T2DM than those in the
lowest quantile (none or < 1 serving/month) (RR:1.26 (95% CI: 1.12, 1.41)).
Among studies evaluating MetSyn, including 19,431 participants and 5,803
cases, the pooled RR was 1.20 (95% CI: 1.02, 1.42)"
-
Nutrition and aging skin: sugar and glycation - Clin Dermatol. 2010
Jul-Aug;28(4):409-11 - "The effect of sugars on
aging skin is governed by the simple act of covalently cross-linking two
collagen fibers, which renders both of them incapable of easy repair.
Glucose and fructose link the amino acids present in the collagen and
elastin that support the dermis, producing advanced glycation end products
or "AGEs." This process is accelerated in all body tissues when sugar is
elevated and is further stimulated by ultraviolet light in the skin. The
effect on vascular, renal, retinal, coronary, and cutaneous tissues is being
defined, as are methods of reducing the glycation load through careful diet
and use of supplements"
-
Sweetened beverage consumption and risk of coronary heart disease in women
- Am J Clin Nutr. 2009 Feb 11 - "sugar-sweetened
beverages (SSBs) ... After standard and dietary risk factors were adjusted
for, the RRs (and 95% CIs) of CHD according to categories of cumulative
average of SSB consumption (<1/mo, 1-4/mo, 2-6/wk, 1/d, and >/=2 servings/d)
were 1.0, 0.96 (0.87, 1.06), 1.04 (0.95, 1.14), 1.23 (1.06, 1.43), and 1.35
(1.07, 1.69)"
-
Dietary
Green Tea Extract Lowers Plasma and Hepatic Triglyceride and Decreases the
Expression of Sterol Regulatory Element-Binding Protein-1c mRNA and Its
Responsive Genes in Fructose-Fed Ovariectomized Rats - J Nutr. 2009 Feb
4 - "Fructose elevated plasma TG and cholesterol
compared with the S group. GT at 0.5 and 1.0% markedly lowered plasma and
liver TG. Fructose increased the expression of SREBP-1c, fatty acid synthase,
and stearoyl-CoA desaturase 1 mRNAs in the liver, whereas GT decreased the
expression of these lipogenic genes. Similarly, fructose increased the
abundance of hepatic 3-hydroxy-3-methyl-glutaryl-CoA reductase mRNA, whereas
GT significantly decreased its expression ... the lipid-lowering effect of
GT is mediated partly by its inhibition of hepatic lipogenesis involving
SREBP-1c and its responsive genes without affecting lipoprotein assembly"
- See
Jarrow green tea extract at iHerb
 .
-
Straight
talk about high-fructose corn syrup: what it is and what it ain't - Am J
Clin Nutr. 2008 Dec;88(6):1716S-1721S - "Although
examples of pure fructose causing metabolic upset at high concentrations
abound, especially when fed as the sole carbohydrate source, there is no
evidence that the common fructose-glucose sweeteners do the same. Thus,
studies using extreme carbohydrate diets may be useful for probing
biochemical pathways, but they have no relevance to the human diet or to
current consumption. I conclude that the HFCS-obesity hypothesis is
supported neither in the United States nor worldwide"
-
Fructose
consumption and consequences for glycation, plasma triacylglycerol, and body
weight: meta-analyses and meta-regression models of intervention studies
- Am J Clin Nutr. 2008 Nov;88(5):1419-37 - "The
meta-analysis shows that fructose intakes from 0 to >or=90 g/d have a
beneficial effect on HbA(1c). Significant effects on postprandial
triacylglycerols are not evident unless >50 g fructose/d is consumed, and no
significant effects are seen for fasting triacylglycerol or body weight with
intakes of <or=100 g fructose/d in adults" - I don't get it. It
would seem like fructose would make HbA(1c) worse.
-
Dietary fructose and the metabolic syndrome - Curr Opin Gastroenterol.
2008 Mar;24(2):204-9 - "Recent animal studies have
confirmed the link between fructose feeding and increased plasma uric acid,
a potentially causative factor in metabolic syndrome. Advanced glycation end
products are also implicated because of their direct protein modifications
and indirect effects on inflammation and oxidative stress. Human studies
have demonstrated fructose's ability to change metabolic hormonal response,
possibly contributing to decreased satiety ... There is much evidence from
both animal models and human studies supporting the notion that fructose is
a highly lipogenic nutrient that, when consumed in high quantities,
contributes to tissue insulin insensitivity, metabolic defects, and the
development of a prediabetic state"
-
Sugar-sweetened soft drinks, diet soft drinks, and serum uric acid level:
The third national health and nutrition examination survey - Arthritis
Rheum. 2007 Dec 28;59(1):109-116 - "sugar-sweetened
soft drink consumption is associated with serum uric acid levels and
frequency of hyperuricemia, but diet soft drink consumption is not"
-
Dietary glycemic load, added sugars, and carbohydrates as risk factors for
pancreatic cancer: the Multiethnic Cohort Study - Am J Clin Nutr. 2007
Nov;86(5):1495-501 - "Glycemic load and added sugars
were not significantly associated with pancreatic cancer risk. The risk
increased with higher intakes of total sugars, fructose, and sucrose, and
the association with fructose was significant when the highest and lowest
quartiles were compared (relative risk: 1.35; 95% CI: 1.02, 1.80; P for
trend = 0.046). A significant association was found with fruit and juices
intake (1.37; 1.02, 1.84; P for trend = 0.04) but not with soda intake.
Statistical evidence of a significant interaction with body mass index was
present only for sucrose intake (P = 0.04). A comparison of the highest and
lowest quartiles of sucrose intake in overweight or obese participants gave
a relative risk of 1.46 (0.95-2.25; P for trend = 0.04), but the comparison
was not significant in normal-weight participants"
-
Fructose intake is a predictor of LDL particle size in overweight
schoolchildren - Am J Clin Nutr. 2007 Oct;86(4):1174-1178 -
"After control for adiposity, the only dietary
factor that was a significant predictor of LDL particle size was total
fructose intake"
-
Potential role of sugar (fructose) in the epidemic of hypertension, obesity
and the metabolic syndrome, diabetes, kidney disease, and cardiovascular
disease - Am J Clin Nutr. 2007 Oct;86(4):899-906 -
"We also present evidence that the unique ability of
fructose to induce an increase in uric acid may be a major mechanism by
which fructose can cause cardiorenal disease"
-
Consumption of sweetened beverages and intakes of fructose and glucose
predict type 2 diabetes occurrence - J Nutr. 2007 Jun;137(6):1447-54 -
"Combined intake of fructose and
glucose was associated with the risk of type 2 diabetes but no significant
association was observed for intakes of sucrose, lactose, or maltose. The
relative risk between the highest and lowest quartiles of combined fructose
and glucose intake was 1.87"
-
High fructose diet increases mortality in hypertensive rats compared to a
complex carbohydrate or high fat diet - Am J Hypertens. 2007
Apr;20(4):403-9 - "a high fructose
diet consumed during hypertension increases mortality and left ventricular
(LV) wall thickness compared to either a high fat, high starch, or a
"western" diet"
-
A 4-wk high-fructose diet alters lipid metabolism without affecting insulin
sensitivity or ectopic lipids in healthy humans - Am J Clin Nutr. 2006
Dec;84(6):1374-9 - "Moderate
fructose supplementation over 4 wk increases plasma triacylglycerol and
glucose concentrations without causing ectopic lipid deposition or insulin
resistance in healthy humans"
-
Catalytic amounts of fructose may improve glucose tolerance in subjects with
uncontrolled non-insulin-dependent diabetes - Clin Nutr. 2006 Jan 3 -
"were assigned to either fructose or
maltodextrin supplementation (7.5g) tri-daily after each main meal ... After
1 month fructosamin levels decreased in the fructose-supplemented group but
not in the maltodextrin-supplemented group (P<0.052). Hgb(A1C) levels
decreased with time in both groups but were significantly lower at 2 months
in the fructose group as compared to the maltodextrin group"
Where to purchase fructose separately:
Related Searches:
70926
|
