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Home > Anti-aging Research > Cytokines.
Cytokines
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Alternative News:
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Antioxidative and Anti-Inflammatory Protection from Carnosine in the Striatum of
MPTP-Treated Mice - J Agric Food Chem. 2010 Oct 6 - "The preintake of
carnosine significantly attenuated MPTP-induced glutathione loss, retained the
activity of GPX and SOD, diminished oxidative stress, and lowered inflammatory
cytokines and nitrite levels as well as suppressed iNOS activity (P < 0.05).
MPTP treatment significantly suppressed GPX mRNA expression and enhanced iNOS
mRNA expression (P < 0.05). Carnosine preintake significantly elevated GPX mRNA
expression and declined iNOS mRNA expression (P < 0.05). Preintake of carnosine
also significantly improved MPTP-induced dopamine depletion and maintained
3,4-dihydroxyphenylacetic acid and homovanillic acid levels (P < 0.05). These
results suggest that carnosine could provide antioxidative and anti-inflammatory
protection for the striatum against the development of Parkinson's disease" -
See l-carnosine products at iHerb.

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Resveratrol shows metabolic benefits for obese: Study - Nutra USA, 10/11/10
- "When human fat cells were exposed to IL-1B, the
researchers noted increases in the secretion of pro-inflammatory compounds,
including IL6, IL8, MCP-1. However, when the cells were simultaneously exposed
to resveratrol, a 16 to 36 percent reduction in the expression of these
cytokines was observed" - [Abstract]
- See
resveratrol products at iHerb
.
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Anti-inflammatory effect of resveratrol on adipokine expression and secretion in
human adipose tissue explants - Int J Obes (Lond). 2010 Jun 8 -
"This study
is the first to show anti-inflammatory effects of RSV on adipokine expression
and secretion in human adipose tissue in vitro through the SIRT1 pathway. Thus,
RSV is hypothesized to possess beneficial effects and might improve the
metabolic profile in human obesity" - See
resveratrol products at iHerb.

General Information:
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Cytokine - American Academy of Family Physicians
- Cytokine - emedicine.com
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Cytokine - familydoctor.org
- Books on Cytokine - Amazon.com
News & Research:
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What role do cytokines play in autoimmune diseases? - Science Daily,
10/27/11
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Inflammation May Be Link Between Extreme Sleep Durations And Poor Health
- Science Daily, 2/7/09
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Vitamin E Shows Possible Promise In Easing Chronic Inflammation -
Science Daily, 12/4/08 - "the larger take-home
message of the study, published in the December issue of the journal
Experimental Physiology, is that Vitamin E “may be beneficial in individuals
with chronic inflammation, such as the elderly or patients with type II
diabetes or chronic heart failure" - See
Jarrow FamilE (contains all eight members of the vitamin E family) at iHerb
.
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Proinflammatory Cytokines Could Help Improve Diagnosis And Treatment Of
Prostate Cancer - Science Daily, 12/3/08
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Red
Wine's Resveratrol May Help Battle Obesity - Science Daily, 6/16/08 -
"resveratrol inhibited the pre-fat cells from
increasing and prevented them from converting into mature fat cells. Also,
resveratrol hindered fat storage. Most interesting, according to Fischer-Posovszky,
was that resveratrol reduced production of certain cytokines (interleukins 6
and 8), substances that may be linked to the development of obesity-related
disorders, such as diabetes and clogged coronary arteries. Also, resveratrol
stimulated formation of a protein known to decrease the risk of heart
attack. Obesity decreases this substance, called adiponectin" - See
Jarrow Resveratrol 100 at iHerb
.
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Curcumin Suppresses IgE-Mediated Allergic Response and Mast Cell Activation
- Medscape, 6/3/08 - "Two cytokines, TNF-alpha and
IL-4, are among those that are critical to allergic inflammation. In studies
using the RBL-2H3 tumor mast cell line, the researchers found that curcumin
significantly inhibited the antigen-stimulated expression of mRNA for both
cytokines, and the secretion of both cytokines in the mast cells, in a
dose-dependent manner" - See
curcumin/turmeric products at iHerb
.
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Link
Between Inflammation, Cancer Confirmed - Science Daily, 6/2/08 -
"Chronic inflammation of the intestine or stomach
can damage DNA, increasing the risk of cancer ... Researchers have long
known that inflammation produces cytokines (immune response chemicals that
encourage cell proliferation and suppress cell death), which can lead to
cancer"
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Protein Found That May Provide Relief From Neuropathic Pain - Science
Daily, 12/5/07
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Depression
Associated With Low Bone Mineral Density - Medscape, 12/3/07 -
"The novelty of this study is the fact that these
women were not severely depressed ... Depression is considered a disease of
chronic stress, Dr. Cizza said, with attendant increases in the stress
hormone cortisol, and cytokines produced by the immune system. "Those
substances are helpful to fight stress, but if there is too much cortisol or
cytokines, there are side effects," he said. "One of the side effects is
bone loss, so it was obvious to ask the question, 'do women with depression
have low bone mass?'""
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Exercise May Play Role In Reducing Inflammation In Damaged Skin Tissue -
Science Daily, 11/28/07 - "moderate exercise sped up
how fast wounds heal in old mice ... the improved healing response “may be
the result of an exercise-induced anti-inflammatory response in the wound.”
... Cytokines are molecules that signal and direct immune cells, such as
macrophages, to the site of an infection ..."
- Blood
Inflammation Plays Role in Alzheimer's Disease - Doctor's Guide, 5/29/07
- "The participants' blood was
tested for levels of cytokines, which are protein messengers that trigger
inflammation. Those with the highest amount of cytokines in their blood were
more than twice as likely to develop Alzheimer's disease as those with the
lowest amount of cytokines"
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Cytokines Play Role in Sleep Disorders, Obesity - Clinical Psychiatry
News, 10/06 - "Interventions to
reduce or neutralize proinflammatory cytokines may be novel treatments in
patients with sleep disorders and obesity ... Three inflammation-associated
cytokines—tumor necrosis factor-α (TNF-α, interleukin-1 (IL-1), and IL-6—are
elevated in obese and sleep-deprived patients, and may mediate excessive
daytime sleepiness and fatigue"
- High
Cytokine Levels Linked to Fatigue and Cognitive Impairment - Medscape,
8/24/06
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Cytokines
Play Crucial Role In Depression-Cardiac Link - Psychiatric News,
10/21/05
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Fibrogenic Cytokines May Play Role in Nephrogenic Fibrosing Dermatopathology - Doctor's Guide, 10/15/02
- Cytokine Levels Signal Worse Prognosis in Severe Sepsis - Doctor's Guide, 9/20/02
- Growth Hormone Benefits Cardiomyopathy Patients - Doctor's Guide, 9/2/02 -
"Growth hormone reduces serum
levels of proinflammatory cytokines in patients with chronic heart failure secondary to idiopathic dilated cardiomyopathy.
It also reduces soluble Fas and soluble Fas ligand
system in these patients ... The investigators also observed significant improvements in peak oxygen consumption"
Abstracts:
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