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Home > Anti-aging Research > Cytokines.

Cytokines

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  • Antioxidative and Anti-Inflammatory Protection from Carnosine in the Striatum of MPTP-Treated Mice - J Agric Food Chem. 2010 Oct 6 - "The preintake of carnosine significantly attenuated MPTP-induced glutathione loss, retained the activity of GPX and SOD, diminished oxidative stress, and lowered inflammatory cytokines and nitrite levels as well as suppressed iNOS activity (P < 0.05). MPTP treatment significantly suppressed GPX mRNA expression and enhanced iNOS mRNA expression (P < 0.05). Carnosine preintake significantly elevated GPX mRNA expression and declined iNOS mRNA expression (P < 0.05). Preintake of carnosine also significantly improved MPTP-induced dopamine depletion and maintained 3,4-dihydroxyphenylacetic acid and homovanillic acid levels (P < 0.05). These results suggest that carnosine could provide antioxidative and anti-inflammatory protection for the striatum against the development of Parkinson's disease" - See l-carnosine products at iHerb.
  • Resveratrol shows metabolic benefits for obese: Study - Nutra USA, 10/11/10 - "When human fat cells were exposed to IL-1B, the researchers noted increases in the secretion of pro-inflammatory compounds, including IL6, IL8, MCP-1. However, when the cells were simultaneously exposed to resveratrol, a 16 to 36 percent reduction in the expression of these cytokines was observed" - [Abstract] - See resveratrol products at iHerb.
  • Anti-inflammatory effect of resveratrol on adipokine expression and secretion in human adipose tissue explants - Int J Obes (Lond). 2010 Jun 8 - "This study is the first to show anti-inflammatory effects of RSV on adipokine expression and secretion in human adipose tissue in vitro through the SIRT1 pathway. Thus, RSV is hypothesized to possess beneficial effects and might improve the metabolic profile in human obesity" - See resveratrol products at iHerb.

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