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Home > Health Conditions > Creatinine

Creatinine

Alternative News:

  • Tocotrienol-rich vitamin E improves diabetic nephropathy and persists 6-9 months after washout: a phase IIa randomized controlled trial - Ther Adv Endocrinol Metab. 2019 Dec 25 - "receive Tocovid 200 mg or placebo for 12 weeks ... Patients were reassessed 6-9 months post-washout. After 12 weeks of supplementation, Tocovid significantly decreased serum creatinine levels (mean difference: -3.3 ± 12.6 versus 5.4 ± 14.2, p = 0.027) and significantly increase eGFR (mean difference: 1.5 ± 7.6 versus -2.9 ± 8.0, p = 0.045) compared with placebo ... Subgroup analysis revealed that in patients with low serum vitamin E concentrations at baseline, Tocovid reduced serum creatinine, eGFR, and VCAM-1 significantly. After 6-9 months of washout, persistent difference in serum creatinine remained between groups (mean difference: 0.82 ± 8.33 versus 11.26 ± 15.47, p = 0.031), but not eGFR. Tocovid at 400 mg/day significantly improved renal function in 12 weeks of supplementation, as assessed by serum creatinine and eGFR, which remained significant 6-9 months post-washout" - [Nutra USA] - See Tocovid at Amazon.com.
  • Pine bark extract may benefit blood pressure-related kidney health - Nutra USA, 3/5/10 - "55 hypertensive patients to participate in the randomized, controlled study. Subjects were assigned to receive Ramipril [an ACE inhibitor] (10 mg per day), and 29 of these people were randomly selected to also receive Pycnogenol (150 mg per day) ... After six months in the Ramipril-only group the albumin levels decreased by 26 per cent to 64 mg per 24-hour period, while additional Pycnogenol produced levels that averaged 39 mg per 24-hour period, equivalent to a 57 per cent decrease ... Statistically significant decreases in patients’ blood pressure were also observed, with systolic and diastolic blood pressures dropping by more than 30 and 8 per cent, respectively in the Ramipril-only group, and by a further 3 to 6 per cent in the combination group ... Diastolic and systolic blood flow improved by 8 and 12 per cent, in the combination group" - [Abstract] - See Pycnogenol at Amazon.com.
  • Kidney flow and function in hypertension: protective effects of pycnogenol in hypertensive participants--a controlled study - J Cardiovasc Pharmacol Ther. 2010 Mar;15(1):41-6 - "evaluated the effects of Pycnogenol as an adjunct to angiotensin-converting enzyme (ACE)-inhibitor ramipril treatment of hypertensive patients presenting with early signs of renal function problems. One group of 26 patients was medicated with 10 mg ramipril per day only; a second group of 29 patients took Pycnogenol in addition to the ACE inhibitor over a period of 6 months ... Urinary albumin decreased from 87 +/- 23 to 64 +/- 16 mg/d with ramipril only. Additional Pycnogenol lowered albumin significantly better from 91 +/- 25 to 39 +/- 13 mg/day (P < .05). In both groups, serum creatinine was lowered; however, only in the combination treatment group did the effect reached statistical significance. In both groups, CRP levels decreased from 2.1 to 1.8 with ramipril and from 2.2 to 1.1 with the ramipril-Pycnogenol combination; the latter reached statistical significance. Kidney cortical flow velocity was investigated by Doppler color duplex ultrasonography. Both systolic and diastolic flow velocities increased significantly after 6 months medication with ramipril. The addition of Pycnogenol to the regimen statistically significantly further enhanced kidney cortical flow velocities, by 8% for diastolic flow and 12% for systolic flow, relative to values found for the group taking ramipril only" - See Pycnogenol at Amazon.com.
  • Omega-3 may boost kidney health in diabetics: Study - Nutra USA, 2/3/10 - "Our results showed a significant decrease in serum creatinine level after fish-oil supplement in Type 2 diabetes mellitus patients" - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.
  • Fish-oil supplement has neutral effects on vascular and metabolic function but improves renal function in patients with Type 2 diabetes mellitus - Diabet Med. 2010 Jan;27(1):54-60 - "serum creatinine was lower (-4.5 mumol/l, P = 0.01) in fish-oil-treated patients as compared with control subjects" - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.

Other News:

  • Protein in the urine: A warning sign for cognitive decline - Science Daily, 11/21/10 - "low amounts of albumin in the urine, at levels not traditionally considered clinically significant, strongly predict faster cognitive decline in older women ... participants with a urinary albumin-to-creatinine ratio of >5 mcg/mg at the start of the study experienced cognitive decline at a rate 2 to 7 times faster in all cognitive measures than that attributed to aging alone over an average 6 years of follow-up"
  • Serum Creatinine and Prostate Cancer Risk in a Prospective Study - Cancer Epidemiol Biomarkers Prev. 2009 Sep 15 - "Cases had significantly higher prediagnostic serum creatinine concentrations compared with controls (medians of 1.13 versus 1.10 mg/dL, respectively; P = 0.004). Serum creatinine was associated with a significantly greater risk of prostate cancer (multivariate odds ratio, 2.23; 95% confidence interval, 1.33-3.75 for highest versus lowest quartile), with a significant trend (P trend = 0.0008)"
 

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