Welcome to the Quality Counts. For those health conscious consumers and medical professionals that are looking to purchase nutritional supplements, vitamins, herbs, learning about medications, losing weight, health food, low carbs, high protein nutrition, and exercise, you have come to the right place. Quality Counts serves both the medical practitioner and consumer interested in nutritional therapy and alternative medicine.

Home > Health Conditions > Colon Cancer.

Colon Cancer

Popular Supplements:

• NutraFlora® FOS / folic acid / vitamin D / aspirin / calcium / IP-6 / selenium / green tea
• See Cancer Cures?

Alternative News:

• Colorectal Cancer - Life Extension Foundation
• Colon Cancer - Vitacost
• Omega-3 linked to lower colorectal cancer risk - Nutra USA, 5/16/08 - "In terms of fish intake, the highest average intake was associated with a 40 per cent reduction in the risk of colorectal cancer. In addition, this link was relevant for both colon and rectal cancers" - See Mega Twin EPA at iHerb.
• Impact of postoperative omega-3 fatty acid-supplemented parenteral nutrition on clinical outcomes and immunomodulations in colorectal cancer patients - World J Gastroenterol. 2008 Apr 21;14(15):2434-2439 - "Patients in the FO group trended to need a shorter postoperative hospital stay (17.45 +/- 4.80 d vs 19.62 +/- 5.59 d, P = 0.19) ... Postoperative supplementation of omega-3 fatty acids may have a favorable effect on the outcomes in colorectal cancer patients undergoing radical resection by lowering the magnitude of inflammatory responses and modulating the immune response" - See Mega Twin EPA at iHerb.
• Vitamin D And Calcium Influence Cell Death In The Colon, Researchers Find - Science Daily, 4/13/08 - "We were pleased that the effects of calcium and vitamin D were visible enough in this small study to be significant and reportable"
• Folate and MTHFR: risk of adenoma recurrence in the Polyp Prevention Trial - Cancer Causes Control. 2008 Mar 6 - "Low dietary folate intake has been associated with colorectal cancer risk and adenoma recurrence. A C/T transition at position 677 in the gene encoding methlylenetetrahydrofolate reductase (MTHFR C677T) has been reported to interact with folate intake to modulate colorectal adenoma recurrence or cancer risk ... In general, no statistically significant associations were found between quartile of folate intake (dietary or total) and adenoma recurrence ... No significant interaction was noted for total folate and MTHFR genotype, though an increased risk of recurrence noted for the MTHFR CT genotype was statistically significant only for those individuals with below median intake of total folate"
• Aspirin Associated With Reduced Colorectal Cancer Risk in Men - Medscape, 2/12/08 - "men who reported regular aspirin use (at least 2 times per week) had a significantly lower risk of colorectal cancer compared with those who were not regular aspirin users (multivariate RR, 0.79) ... However, men reporting 6 to 14 standard aspirin tablets per week had a multivariate RR of 0.72, and those consuming more than 14 tablets per week experienced a multivariate RR of 0.30" - Note: A RR of 0.79 is a 21% reduction, a RR of 0.30 is a 70% reduction.
• Vitamin D Appears to Cut Breast and Colorectal Cancer Risk - Medscape, 2/12/08 - "Compared with a serum 25-hydroxyvitamin D level less than 12 ng/mL, a level of at least 33 ng/mL or more was associated with a 50% reduction in the risk for incident colorectal cancer ... vitamin D intake of 1000 to 2000 IU per day would confer an appropriate balance between protection against colorectal cancer and adverse events related to hypervitaminosis" - See vitamin D products at iHerb.
• Regular, Long-Term Aspirin Use Reduces Risk of Colorectal Cancer - Doctor's Guide, 1/23/08 - "the benefit of aspirin was not apparent until after more than five years of use. The greatest reduction in risk was observed at cumulative doses of more than 14 standard tablets (325 mg) per week, which is higher than normally recommended. The benefit of aspirin use appears to diminish less than four years after stopping use and is not evident after four to five years of discontinued use"
• Recreational Physical Activity and Cancer Risk in Subsites of the Colon (the Nord-Trondelag Health Study) - Cancer Epidemiol Biomarkers Prev. 2008 Jan;17(1):183-8 - "Overall, we found an inverse association between recreational physical activity and colon cancer risk, but subsite analyses showed that the association was confined to cancer in the transverse and sigmoid colon. The adjusted HR, comparing people who reported high versus no physical activity, was 0.44 (95% CI, 0.25-0.78) for cancer in the transverse colon and 0.48 (95% CI, 0.31-0.75) for cancer in the sigmoid colon. The corresponding HR for cancer mortality was 0.33 (95% CI, 0.14-0.76) for the transverse colon and 0.29 (95% CI, 0.15-0.56) for the sigmoid colon. For rectal cancer, there was no association with physical activity in these data"
• Vitamin B6 may slash colorectal cancer risk - Nutra USA, 1/17/08 - "High vitamin B6 intakes were reported to reduce the risk of colorectal cancer by 19 per cent. The protective effect was found to be higher among 55-year-old individuals (1,001 cases compared to 1,010 controls)" - [Abstract]
• Dietary vitamin b6 intake and the risk of colorectal cancer - Cancer Epidemiol Biomarkers Prev. 2008 Jan;17(1):171-82 - "Moderately strong inverse and dose-dependent associations in the whole sample were found between CRC risk and the intake of dietary and total vitamin B6 in all three models [model III: odds ratio (OR), 0.77; 95% confidence interval (95% CI), 0.61-0.98; P for trend = 0.03; OR, 0.86; 95% CI, 0.69-1.07; P for trend = 0.12]. In addition, meta-analyses of published studies showed inverse associations between vitamin B6 and CRC (combined relative risk, 0.81; 95% CI, 0.68-0.96; test for overall effect P = 0.01; combined odds ratio, 0.67; 95% CI, 0.60-0.75; test for overall effect P < 0.00001)"
• Childhood Dairy Intake Linked to Colon Cancer - oncologystat.com, 12/19/07 - "Those who reported high levels of dairy during childhood were about 3 times more likely to develop colon cancer than those with low intake. A high intake was considered 2 or more cups a day, with a low intake being half a cup or less"
• Childhood dairy intake and adult cancer risk: 65-y follow-up of the Boyd Orr cohort - Am J Clin Nutr. 2007 Dec;86(6):1722-9 - "High childhood total dairy intake was associated with a near-tripling in the odds of colorectal cancer [multivariate odds ratio: 2.90 (95% CI: 1.26, 6.65); 2-sided P for trend = 0.005] compared with low intake, independent of meat, fruit, and vegetable intakes and socioeconomic indicators"
• Elevated Insulin, Glucose Raise Risk of Polyp Recurrence - Medscape, 12/10/07 - "patients with elevated insulin or glucose at the time of adenoma removal are at increased risk for recurrent adenoma ... Levels of glucose that produced the increased risk in this study were actually not very high, 99 mg/dL, which is right at the border of what we would describe as impaired fasting glucose ... the odds ratio for a recurrent polyp with advanced histology or large size was 2.43 at a fasting glucose level above 99 mg/dL ... These results "fit with the theory that insulin resistance, hyperinsulinemia, and hyperglycemia promote the development of colorectal neoplasia,""
• Chemoprevention, Naturally: Findings On Plant-derived Cancer Medicines - Science Daily, 12/6/07 - "rats fed a diet containing Polyphenon E, a standardized green tea polyphenol preparation, are less than half as likely to develop colon cancer ... After 34 weeks, rats that received Polyphenon E developed 55 percent fewer tumors compared to the control rats that did not receive Polyphenon E. Moreover, the tumors were 45 percent smaller in rats treated with green tea extract" - See Jarrow green tea at iHerb.
• Aspirin and Folic Acid for the Prevention of Recurrent Colorectal Adenomas - Gastroenterology. 2007 Oct 10 - "In total, 99 (22.8%) of 434 patients receiving aspirin had a recurrent adenoma compared with 121 (28.9%) of 419 patients receiving placebo (relative risk, 0.79"
• Grape Powder Blocks Genes Linked To Colon Cancer - Science Daily, 11/14/07 - "The Wnt pathway has been linked to more than 85 percent of sporadic colon cancers, which is the most common form of colon cancer ... Wnt signaling in the patients taking 80 grams of grape powder was significantly reduced ... Eighty grams of grape powder equal a half glass of wine or 1 pound of grapes, which is equivalent to three dietary servings of grapes, according to the USDA"
• Riboflavin boosts folate's colorectal cancer protection - study - Nutra USA, 10/29/07
• Mesalamine, Folic Acid Each Cut Colorectal Cancer in Patients With Inflammatory Bowel Disease - oncologystat.com, 10/24/07 - "Patients who took at least 1 mg of folic acid daily also had about a 90% cut in their CRC incidence during follow-up, compared with the controls" - See iHerb folic acid products.
• Omega-3 to cut colon cancer: meta-analysis - Nutra USA, 10/25/07 - "the highest consumption of fish oil was associated with 12 per cent reduction in the incidence of colorectal cancer" - [Abstract] - See Mega Twin EPA at iHerb.
• Proanthocyanidin from grape seeds inactivates the PI3-kinase/PKB pathway and induces apoptosis in a colon cancer cell line - Cancer Lett. 2007 Oct 6 - "grape seed proanthocyanidin extract (GSPE) ... GSPE (10-100mug/ml) significantly inhibited cell viability and increased apoptosis in CaCo2 cells, but did not alter viability in the normal colon cell line (NCM460). The increased apoptosis observed in GSPE-treated CaCo2 cells correlated with an attenuation of PI3-kinase (p110 and p85 subunits) and decreased PKB Ser(473) phosphorylation. GSPE might thus exert its beneficial effects by means of increased apoptosis and suppression of the important PI3-kinase survival-related pathway" - See grape seed products at iHerb.
• Curcumin enhances the effects of 5-fluorouracil and oxaliplatin in mediating growth inhibition of colon cancer cells by modulating EGFR and IGF-1R - Int J Cancer. 2007 Oct 4 - "inclusion of curcumin to the conventional chemotherapeutic agent(s)/regimen could be an effective therapeutic strategy for colorectal cancer" - See curcumin/turmeric products at iHerb.
• Fruits, Veggies Don’t Cut Colon Cancer - WebMD, 9/25/07 - "Overall, a higher intake of fruits and vegetables does not strongly reduce your risk of colon cancer"
• CLA isomers show promise against colon cancer - study - Nutra USA, 9/24/07 - "We have demonstrated that diets containing 0.1 per cent c9,t11 and t10,c12 CLA were equally effective in inhibiting colon cancer cell metastasis in vivo" - See CLA products at iHerb.
• Influence of conjugated linoleic acid isomers on the metastasis of colon cancer cells in vitro and in vivo - J Nutr Biochem. 2007 Oct;18(10):650-7 - "diets containing 0.1% c9,t11 and t10,c12 CLA were equally effective in inhibiting colon cancer cell metastasis in vivo. However, in vitro, only c9,t11 but not t10,c12 inhibited colon cancer cell migration and MMP-9 activity" - See CLA products at iHerb.
• Vitamin D for Cancer Prevention? - WebMD, 9/5/07 - "The 2,000-IU daily dose of vitamin D suggested by the reviewers is currently considered the "tolerable upper limit" for vitamin D ... a projected 50% reduction in colon cancer incidence would require a universal intake of 2,000 IU per day of vitamin D3 ... A similar reduction in breast cancer incidence would require 3,500 IU per day"
• Study Shines More Light On Benefit Of Vitamin D In Fighting Cancer - Science Daily, 8/21/07 - "For the first time, we are saying that 600,000 cases of breast and colorectal cancer could be prevented each year worldwide, including nearly 150,000 in the United States alone ... The serum level recommended by the study would correspond to intake of 2000 International Units per day of vitamin D3 for a meaningful reduction in colorectal cancer" - See vitamin D products at iHerb.
• Colon Cancer on curcumin and Vectibix - Johns Hopkins, 8/14/07 - "University of Texas researchers treated some human colorectal cancer cells with neurotensin, with and without curcumin. They confirmed that neurotensin started a chain reaction of chemicals that can increase the growth of cancer and also the migration of cancer cells and that curcumin blocked the process ... Curcumin appears to do this by blocking the biochemical signals sent by neurotensin that contribute to colon cancer cell growth and migration (the spread of cancer to other body sites)" - See curcumin/turmeric products at iHerb.
• Inhibition Of Tumorigenesis in Apc(Min/+) Mice by a Combination of (-)-Epigallocatechin-3-gallate and Fish Oil - J Agric Food Chem. 2007 Aug 16 - "The effect of a combination of (-)-epigallocatechin-3-gallate (EGCG) with fish oil on intestinal tumorigenesis in Apc (Min/+) mice fed a high-fat diet was investigated in the present study. The combined treatment of EGCG and fish oil for 9 weeks reduced the tumor number by 53% as compared to controls while neither agent alone had a significant effect. Apoptosis was significantly increased in all treatment groups" - See Mega Twin EPA at iHerb and Jarrow green tea at iHerb.
• Compounds That Color Fruits And Veggies May Protect Against Colon Cancer - Science Daily, 8/19/07 - "In animal studies, rats induced with colon cancer cells were fed a daily diet of anthocyanin extracts either from bilberries and chokeberries, which are most often used as flavorings or to make jams and juices. The dietary addition of the anthocyanin extracts reduced signs of colon tumors by 70 and 60 percent, respectively, when compared to control rats"
• Green tea may stop colon cancer in its tracks - study - Nutra USA, 8/9/07 - "At the age of eight weeks, the mice were divided into two groups - one to receive water or a green tea solution (0.6 per cent) as the only beverage source for a further four to eight weeks ... consumption of the green tea solution significantly inhibited the formation of new tumours in the colon" - See Jarrow green tea at iHerb.
• Green tea selectively targets initial stages of intestinal carcinogenesis in the AOM-ApcMin mouse model - Carcinogenesis. 2007 Jul 17 - "green tea specifically targets initial stages of colon carcinogenesis; the time of administration of green tea is pivotal for effective chemoprevention. Beverage levels of GT are not likely to inhibit the progress of any large adenomas or adenocarcinomas existing prior to the tea administration"
• A Nested Case-Control Study of Plasma 25-Hydroxyvitamin D Concentrations and Risk of Colorectal Cancer - J Natl Cancer Inst. 2007 Jul 10 - "Our data provide additional support for the inverse association between vitamin D and colorectal and, in particular, colon cancer risk"
• Mistletoe in Supportive Care for Colorectal and Pancreatic Cancers - Doctor's Guide, 7/12/07 - "Use of a fermented mistletoe extract (MEx; Iscador®) in long-term supportive care in hospitals and private practices demonstrated significant survival benefit and improvements in quality of life for patients with surgically treated primary, nonmetastatic colorectal carcinoma and for patients with all-stages pancreatic carcinoma, when combined with adjuvant chemotherapy and/or radiotherapy or passive aftercare in two multicentre, controlled, retrospective, epidemiological, observational, cohort studies"
• A Nested Case-Control Study of Plasma 25-Hydroxyvitamin D Concentrations and Risk of Colorectal Cancer - J Natl Cancer Inst. 2007 Jul 10 - "we observed a non-statistically significant inverse association between higher plasma 25(OH)D concentration and risk of colorectal cancer and a statistically significant inverse association for colon cancer (highest versus lowest quintile: odds ratio [OR] = 0.46, 95% confidence interval [CI] = 0.24 to 0.89; P(trend) = .005). After pooling the results from the HPFS and NHS, higher plasma 25(OH)D concentrations were statistically significantly associated with decreased risks of both colorectal cancer (highest versus lowest quintile, OR = 0.66, 95% CI = 0.42 to 1.05; P(trend) = .01) and colon cancer (highest versus lowest quintile, OR = 0.54" - See vitamin D products at iHerb.
• Different omega-3 may offer different colorectal protection - Nutra USA, 7/11/07 - "Increased intake of EPA was associated with a 41 per cent reduction in risk, while DHA was associated with a 37 per cent reduction in risk, comparing highest against lowest average intakes" - [Abstract] - See Mega Twin EPA at iHerb.
• Dietary Fatty acids and colorectal cancer: a case-control study - Am J Epidemiol. 2007 Jul 15;166(2):181-95 - "Significant dose-dependent reductions in risk were associated with increased consumption of omega-3 polyunsaturated fatty acids (highest vs. lowest quartile of intake: odds ratio = 0.63, 95% confidence interval: 0.50, 0.80; p < 0.0005 for trend) and of eicosapentaenoic (odds ratio = 0.59, 95% confidence interval: 0.47, 0.75; p < 0.0005 for trend) and docosahexaenoic (odds ratio = 0.63" - See Mega Twin EPA at iHerb.
• Vitamin D Fights Colon Cancer - WebMD, 7/10/07 - "The findings support a number of previous studies that link vitamin D to colon cancer protection, to protection against breast and ovarian cancer, to protection against pancreatic cancer, and to overall reduction of cancer risk" - See vitamin D products at iHerb.
• Low Intake of Vitamin B-6 Is Associated with Increased Risk of Colorectal Cancer in Japanese Men - J Nutr. 2007 Jul;137(7):1808-1814 - "We observed a significant inverse association between vitamin B-6 intake and colorectal cancer in men. Compared with the lowest quartile, the multivariate hazard ratio (95% [CI]) in the highest quartile of intake was 0.69"
• Dietary fiber and colorectal cancer risk: the multiethnic cohort study - Cancer Causes Control. 2007 Jun 8 - "Dietary fiber was inversely associated with colorectal cancer risk in men, but its relation to replacement hormone use and other factors affected its inverse association in women"
• Prospective cohort study of green tea consumption and colorectal cancer risk in women - Cancer Epidemiol Biomarkers Prev. 2007 Jun;16(6):1219-23 - "The multivariate relative risk of CRC was 0.63 (95% confidence interval, 0.45-0.88) for women who reported drinking green tea regularly at baseline compared with nonregular tea drinkers" - I read that as a 37% reduction in risk.  See Jarrow green tea at iHerb. - Ben
• Diet May Influence Survival After Treatment For Stage III Colon Cancer, Study Suggests - Science Daily, 6/4/07
• Life Long Vegetarian Diet Reduces The Risk Of Colorectal Cancer - Science Daily, 5/22/07 - "a vegetarian diet is associated with reduced risk of CRC if started very early in life"
• Aspirin May Stop Colon Cancer - WebMD, 5/10/07 - "people who took a full-dose aspirin tablet every day for at least five years had as much as a 74% lower risk of colon cancer 10 to 14 years later. In the U.S."
• Curcumin for chemoprevention of colon cancer - Cancer Lett. 2007 Apr 18 - "Overwhelming in vitro evidence and completed clinical trials suggests that curcumin may prove to be useful for the chemoprevention of colon cancer in humans" - See curcumin/turmeric products at iHerb.
• Coffee consumption and risk of colorectal cancer in a population-based prospective cohort of Japanese men and women - Int J Cancer. 2007 Apr 20 - "We observed a significant inverse association between coffee consumption and the risk of developing invasive colon cancer among women. Compared with those who almost never consumed coffee, women who regularly consumed 3 or more cups of coffee per day had a RR of 0.44 ... In men, no significant decrease was observed in any colorectal cancer site"
• Berries May Help Prevent Cancer - WebMD, 3/26/07
• Blueberries tackle bowel cancer - BBC News, 3/26/07 - "The key ingredient, pterostilbene, is a natural antioxidant and mops up highly reactive molecules called free radicals that can trigger cancer growth ... Rats given a cancer-causing agent but then fed pterostilbene had far fewer pre-cancers in their bowels than other rats ... The blueberry compound also reduced inflammation and the rate of cell division in the bowel"
• Fruit May Sway Colon Cancer Risk - WebMD, 3/20/07 - "The group that had the lowest risk of having an adenoma was the group that ate a lot of fruit and avoided meat, basically"
• Magnesium intake and colorectal cancer risk in the Netherlands Cohort Study - Br J Cancer. 2007 Feb 12;96(3):510-3 - "Statistically significant inverse trends in risk were observed in overweight subjects for colon and proximal colon cancer across increasing quintiles of magnesium uptake"
• Vitamin D Backed For Cancer Prevention In Two New Studies - Science Daily, 2/8/07 - "Two new vitamin D studies using a sophisticated form of analysis called meta-analysis, in which data from multiple reports is combined, have revealed new prescriptions for possibly preventing up to half of the cases of breast cancer and two-thirds of the cases of colorectal cancer in the United States ... The serum level associated with a 50 percent reduction in risk could be maintained by taking 2,000 international units of vitamin D3 daily plus, when the weather permits, spending 10 to 15 minutes a day in the sun" - See Vitamin D products at iHerb.
• Prolonged effect of calcium supplementation on risk of colorectal adenomas in a randomized trial - J Natl Cancer Inst. 2007 Jan 17;99(2):129-36 - "placebo or 1200 mg of elemental calcium daily for 4 years ... During the first 5 years after randomized treatment ended, subjects in the calcium group still had a substantially and statistically significantly lower risk of any adenoma than those in the placebo group (31.5% versus 43.2%"
• Calcium May Reduce Colon Cancer Risk - WebMD, 1/16/07 - "Patients with a history of nonmalignant polyps took either 1,200 milligrams of calcium in supplement form or a placebo daily for four years ... Calcium use was associated with a 17% lower relative risk for polyp recurrence"
• Colorectal cancer protective effects and the dietary micronutrients folate, methionine, vitamins b6, B12, C, e, selenium, and lycopene - Nutr Cancer. 2006;56(1):11-21 - "a diet containing the dietary micronutrients involved in DNA methylation (folate, methionine, and vitamins B6 and B12) and some of those with antioxidant properties (selenium and vitamins E and C) may have a role to play in lowering colorectal cancer risk and also that such protection can be achieved by dietary means alone"
• More support omega-3 may protect against colorectal cancer - Nutra USA, 11/22/06 - "A diet rich in omega-3 polyunsaturated fatty acids (PUFAs) could reduce the risk of colorectal cancer by 85 per cent"
• Low Folate Diets Found To Increase Risk Of Colorectal Cancer - Science Daily, 11/14/06 - "None of the mice fed a control diet developed tumours whereas 1 in 4 mice on the folate-deficient diet developed at least one tumour"
• Soy, Fish May Cut Cancer Risk - WebMD, 11/14/06 - "men who ate the most fish -- and that was five or more servings per week of fish -- compared to the least fish -- less than one time per week -- had a 40% lower risk of developing colorectal cancer"
• Calcium again linked to lower colorectal cancer risk - Nutra USA, 11/8/06 - "the relative risk of colorectal cancer for the highest calcium intake group was 40 per cent lower compared to the lowest intake group"
• Grape Seed Extract Halts Cell Cycle, Checking Growth Of Colorectal Tumors In Mice - Science Daily, 10/29/06 - "documented a 44 percent reduction of advanced colorectal tumors in the animals, and also revealed, for the first time, the molecular mechanism by which grape seed extract works to inhibit cancer growth" - See iHerb or Vitacost grape seed extracts.
• Red Wine vs. Colon Cancer - WebMD, 10/24/06 - "3% of red wine drinkers had such abnormal growths, compared with nearly 9% of white wine drinkers and almost 10% of teetotalers ... they suggest that a compound found in grapes and red wine – the antioxidant resveratrol -- may cut the odds of getting abnormal colon growths that can become cancerous"
• Resveratrol in red wine could cut colorectal cancer risk - Nutra USA, 10/23/06 - "Drinking more than three glasses of red wine a week could cut the risk of colorectal cancer by almost 70 per cent ... the active component in wine that may be behind the apparent benefits is most likely resveratrol"
• Grape Seed Extract vs. Colon Cancer - WebMD, 10/19/06 - "The cancer cells treated with grape seed extract were more likely to halt their normal growth cycle and die, compared to those not treated with the extract"
• Flavonoids linked to colorectal cancer protection - Nutra USA, 8/9/06 - "A diet rich in certain flavonoids, from eating plenty of fruit and vegetables, could reduce the risk of colorectal cancer by over 40 per cent, says a large observational study from Italy"
• Chemical in Curry May Cut Colon Cancer - WebMD, 8/2/06 - "Each of the patients then received 480 milligrams of curcumin and 20 milligrams of quercetin three times a day for six months ... The results showed that treatment with the curry and onion compounds reduced the average number of polyps by 60%, and decreased their size by 50%" - See iHerb or Vitacost curcumin products and iHerb or Vitacost quercetin products.
• Moderate Exercise Improves Survival Rates For Colon Cancer Survivors - Science Daily, 7/14/06
• Vitamin B6 May Help Prevent Colorectal Cancer - Medscape, 6/10/06 - "There was an inverse association between vitamin B6 intake and colorectal cancer, with the relative risk (RR) for the highest quintile vs the lowest quintile being 0.66 ... Vitamin B6 may have a role in colorectal cancer prevention through reduction of oxidative stress and synthesis of a form of folate required for DNA repair, synthesis, and methylation"
• Moderate Alcohol Consumption Protects Against Colorectal Adenoma - Doctor's Guide, 5/24/06 - "Non-drinkers had a 40% higher risk of adenoma than those in the moderate (1-2 drinks and 2-6 drinks per week) groups. Those drinking 7 or more alcoholic beverages per week had 150% higher risk of adenoma than the moderate groups"
• Lowering Colon Cancer Risk? - Dr. Weil, 5/2/06
• More support that dairy could reduce colorectal cancer risk - Nutra USA, 3/8/06 - "A diet rich in dairy products could cut the risk of colorectal cancer by half, an effect that is not due solely to calcium"
• More support for magnesium against colon cancer - Nutra USA, 1/31/06 - "The hazard ratio, a measure of the risk, was statistically 25 per cent lower for the volunteers with the highest intake of magnesium (more than 356 mg per day)"
• Epidemiology of Vitamin D and Colorectal Cancer: Recent Findings - Medscape, 1/9/06 - "In vitro, animal and clinical studies strongly indicate that vitamin D may have anticancer benefits, including against progression (such as metastasis) in colorectal cancer and possibly other cancers. Thus improving vitamin D status could be potentially beneficial against either incidence or mortality, or both ... Current recommended intakes of vitamin D (for example, 400 IU/day) may be too low to provide maximal benefits, though the precise optimal dose remains unestablished"
• High-fat dairy food and conjugated linoleic acid intakes in relation to colorectal cancer incidence in the Swedish Mammography Cohort - Am J Clin Nutr. 2005 Oct;82(4):894-900 - "For CLA, the multivariate rate ratio of colorectal cancer in a comparison of the 2 extreme quartiles of intake was 0.71 ... These prospective data suggest that high intakes of high-fat dairy foods and CLA may reduce the risk of colorectal cancer" - [Food Navigator]
• Selenium supplementation and colorectal adenomas: An analysis of the nutritional prevention of cancer trial - Int J Cancer. 2005 Oct 10 - "In addition to being associated with a reduced risk of incident CRC [colorectal cancers], selenium supplementation was associated with a significantly reduced risk of prevalent adenomas, but only among subjects with either a low baseline selenium level or among current smokers" - See iHerb or Vitacost selenium products.
• High-Dose Aspirin Prevents Colon Cancer - WebMD, 8/23/05
• Long-Term, Regular Aspirin Use Associated With Significant Reduction in Colorectal Cancer Risk Among Women - Doctor's Guide, 8/23/05 - "Among women who regularly used aspirin (2 or more standard [325-mg] tablets per week), there was a 23% reduced relative risk for colorectal cancer compared with nonregular users. However, significant risk reduction was not observed until more than 10 years of use"
• Calcium Supplements May Help Prevent Polyps - WebMD, 7/19/05 - "people who took calcium had about a 25% lower risk of developing polyps in their colon"
• Fish may protect against colorectal cancer - Nutra USA, 6/15/05 - "People eating less than 14g of fish a day were 40 per cent more likely to develop the cancer than those eating more than 50g per day"
• Vitamin B6 May Help Prevent Colorectal Cancer - Medscape, 6/10/05 - "those in the highest quintile had a 34% lower risk of colorectal cancer (multivariate rate ratio"
• High vitamin B intake cuts risk of colorectal cancer - Nutra USA, 6/6/05
• Preventing Colon Cancer? - Dr. Weil, 5/26/05
• Moderate Exercise Reduces Risk of Colon Cancer Recurrence - Doctor's Guide, 5/20/05 - "disease-free survival was 49% lower in patients who engaged in 18 to 27 MET-hours/week of physical activity, compared with those who exercised less than 3 MET-hours/week. "This is equivalent to a 2 to 3 mph walk a day, 6 days a week, running fast 2 times a week or playing tennis 3 a week,""
• Aspirin May Prevent Colon Cancer Recurrence - Doctor's Guide, 5/20/05 - "Recurrence-free survival was 55% lower in aspirin users than non-users (95% CI, 0.21-0.96), disease-free-survival was 54% lower (95% CI 0.23-0.95), and overall survival was 51% lower"
• Exercise May Cut Risk of Colon Cancer's Return - WebMD, 5/17/05
• Aspirin, COX-2 Inhibitors Effective as Adjuvant Therapy in Stage III Colon - Medscape, 5/16/05 - "The chemotherapy provides about 35% improvement in survival compared with surgery alone for that stage of colon cancer, Dr. Fuchs said in an interview. In comparison, aspirin or the two cyclooxygenase 2 (COX-2) inhibitors produced a reduction in risk of recurrence and death that was about 50% beyond what was achieved by chemotherapy after surgery"
• Aspirin Prevents Colon Cancer Return - WebMD, 5/16/05
• Vitamin B-6 May Help People Avoid Colon Cancer - WebMD, 5/3/05 - "The risk of colorectal cancer was 44% lower for the women with the highest blood level of vitamin B-6 compared with women with the lowest level of vitamin B-6"
• Calcium Supplements Keep on Working Even After They Are Stopped - Doctor's Guide, 4/21/05 - "People at high risk of colon cancer appear to reduce the risk of developing polyps while taking calcium supplements and continue to benefit for as long as 5 years after they stop taking them"
• Statins Lower Prostate Cancer Risk - WebMD, 4/18/05 - "long-term use of calcium supplements protects against the development of potentially precancerous colon polyps for years after you stop taking them"
• Calcium May Help Prevent Colorectal Cancer - WebMD, 1/28/05
• Magnesium intake in relation to risk of colorectal cancer in women - JAMA. 2005 Jan 5;293(1):86-9 - "a high magnesium intake may reduce the occurrence of colorectal cancer in women"
• Selenium May Lower Colon Cancer Risk - WebMD, 11/16/04 - "participants with the highest blood levels of selenium were 34% less likely to develop a new adenoma compared with those with the lowest selenium blood levels"
• Milk, Calcium, May Cut Colon Cancer Risk - WebMD, 7/6/04
• Calcium More Protective Against Some Polyps - WebMD, 6/15/04 - "The calcium group had 18% fewer noncancerous polyps and 35% fewer advanced polyps ... compared with the placebo group ... her study suggests that total calcium intake over 1,200 mg daily is necessary for colon protection -- and that a high-fiber diet with modest levels of fat will boost the protective effects"
• New findings on soy and cancer prevention - Nutra USA, 5/13/04
• Folate and colorectal neoplasia: relation between plasma and dietary markers of folate and adenoma recurrence - Am J Clin Nutr. 2004 Apr;79(4):691-697 - "A lower recurrence of colorectal adenomas was shown in subjects with higher intakes and plasma concentrations of folate. Additional markers involved in folate metabolism, including lower homocysteine and higher vitamin B-6 intake, were also associated with lower odds of recurrence"
• Heme Iron and Zinc Have Opposite Effects on Colon Cancer Risk - Doctor's Guide, 3/29/04 - "heme iron appears to raise the risk of proximal colon cancer while dietary zinc appears to lower the risk of both proximal and distal colon cancer"
• 5 a day force, new evidence - Nutra USA, 2/11/04 - "High intakes of vegetables, fruits and wholegrain foods reduces the risk of rectal cancer by 28 per cent, 27 per cent and 31 per cent, respectively ... High fiber diet – more that 34 grammes a day reduced risk of rectal cancer by a staggering 66 per cent"
• Aspirin Use May Prevent Colon Cancer - WebMD, 2/2/04 - "Regularly taking aspirin -- more than two tablets a week -- reduced the risks of polyps by 25% ... while higher doses of aspirin (325 milligrams per day) may be necessary for optimal prevention of polyps, the risk of severe gastrointestinal bleeding remains a serious concern" - See Drugstore.com aspirin products.
• Effect of an omega-3 fatty acid containing lipid emulsion alone and in combination with 5-fluorouracil (5-FU) on growth of the colon cancer cell line Caco-2 - Eur J Nutr. 2003 Dec;42(6):324-31 - "FO has a potent antiproliferative effect on Caco-2 cells"
• Diet, lifestyle may lower colon cancer risk - MSNBC, 1/23/04 - "One prime suspect now is insulin resistance. In this condition, higher levels of insulin circulate because the body is less responsive to it. Insulin and related growth factors seem to change cell processes in ways that promote the development of cancer"
• Lycopene, ß-carotene, and colorectal adenomas -Am  J  of Clin Nutr, Vol. 78, No. 6, 1219-1224, 12/03 - "Our findings support the hypothesis that lycopene contributes to the protective effect of high tomato intakes against the risk of colorectal adenomas"
• What Causes, Prevents Colon Polyps - WebMD, 12/9/03 - "Just take an aspirin, a multivitamin, and eat a bowl of fiber-packed cereal with some milk ... In this new report, vitamin D shines -- it's associated with a one-third reduced risk of serious colon polyps that often lead to cancer in men getting at least 645 IUs of this nutrient each day"
• Calcium And Vitamin D Collaborate To Reduce Colorectal Cancer Risk - Intelihealth, 12/3/03
• Calcium Intake Plus Vitamin D May Protect Against Colon Adenomas - Medscape, 12/2/03 - "Calcium supplementation reduces the rate of colon adenomas, but only if vitamin D levels are adequate"
• Studies Associate Fish And Multivitamins With Reduced Risk For Colorectal Cancer - Doctor's Guide, 7/16/03 - "Only fish consumption was associated with a reduction in risk ... Both processed meat and red meat consumption were associated with increased risk ... Duration of multivitamin use was associated with a decreased risk of rectal cancer"
• An Aspirin a Day Does Not Reduce Colorectal Cancer Risk Among Smokers - Doctor's Guide, 7/16/03
• Night Shifts May Raise Cancer Risk - WebMD, 6/3/03 - "Data from an ongoing study of almost 80,000 nurses already suggest that working nights increases a woman's risk of breast cancer ... a new analysis points to a similar association for colorectal cancer ... "The peak production of melatonin occurs at about 1 or 2 a.m." Exposure to light at night stops the production of melatonin" - See iHerb or Vitacost melatonin products.
• 2 Studies Contradict Earlier Research Showing No Benefit of Fiber on Colon Cancer Risk - WebMD, 5/1/03 - "What's more consistent is the two newest findings, both published in the May 3 issue of The Lancet ... those eating a high-fiber diet -- upwards of 36 grams of fiber each day -- were 25% less likely to develop polyps than those eating fewer than 12 grams ... The other study, conducted on 520,000 people in 10 European countries and called the largest study ever, also initially found a 25% reduced rate in colorectal cancer in those eating high-fiber diets of about 35 grams daily compared with those eating less than 15 ... the protective effect was greatest on the left side of the colon, where most cancers originate ... Fiber is believed to help reduce risk in two ways: It keeps you regular to remove toxins from the intestines, and bacteria living in the gut feeds on it -- producing beneficial byproducts to keep the colon healthy"
• Europe-Wide Study Finds Fibre Can Cut Colorectal Cancer Risk By Up To 40% - Doctor's Guide, 5/1/03 - "People consuming an average of 35 g fibre a day can cut their risk of colorectal cancer up to 40%, compared to people who consume an average of 15 g per day ... Protection was greatest for the left side of the colon, and least for the rectum ... foods supplying fibre also contribute many other nutrients and phytochemicals that have been linked to cancer protection, and which could account for the protective effects seen"
• Latest Evidence Links High-Fibre Diet With Reduced Colon Cancer Risk - Doctor's Guide, 5/1/03
• Selenium Reduces Risk of Some Cancers: FDA Approves Claim - New Hope Natural Media, 4/17/03 - "Companies that manufacture selenium supplements will now be permitted by the United States Food and Drug Administration (FDA) to claim that selenium supplements may reduce the risk of some cancers, according to a statement by the FDA. Although the FDA does not permit manufacturers to list specific types of cancer in the health claim, studies suggest selenium supplementation may reduce the risk of colon, prostate, lung, liver and esophageal cancers" - See iHerb and Vitacost selenium products.
• Calcium, vitamin D, dairy products, and risk of colorectal cancer in the cancer prevention study II nutrition cohort - Cancer Causes Control 2003 Feb;14(1):1-12 - "Total calcium intake (from diet and supplements) was associated with marginally lower colorectal cancer risk in men and women ... The association was strongest for calcium from supplements ... Total vitamin D intake (from diet and multivitamins) was also inversely associated with risk of colorectal cancer, particularly among men"
• Red Meat + Fats + Pasta = Colon Cancer - WebMD, 2/10/03 - "Women who ate the most Western foods had 50% more colon cancers than the women who ate the least Western foods"
• Low Dietary Copper Increases Fecal Free Radical Production, Fecal Water Alkaline Phosphatase Activity and Cytotoxicity in Healthy Men - J. Nutr. 133:522-527, 2/03 - "One possible dietary factor that may increase susceptibility to colon cancer is inadequate copper intake ... Low dietary copper significantly (P < 0.01) increased fecal free radical production"
• Colon Cancer Rise Linked to Beef, Pork - WebMD, 11/15/02 - "a high intake of red meat -- including beef and pork -- doubled the risk of colorectal cancer. No rise was seen for those reporting increased consumption of other meats or seafood. Eating vegetables was associated with a reduction in risk ... People who ate lots of red meat and few vegetables were more than 2.5 times more likely to get colon cancer"
• More Good News on Tea - WebMD, 9/27/02 - "The latest studies suggest tea might lower cholesterol, improve heart health, prevent rectal cancer in women, and reduce cell damage in smokers" - See iHerb or Vitacost green tea products.
• Folic Acid Fights Colon Cancer - WebMD, 7/19/02
• Folic Acid Supplement Reduces Cell Proliferation In High Risk Colorectal Cancer Patients - Doctor's Guide, 7/18/02 - "Patients at high risk of colorectal cancer could cut their risk dramatically with a daily supplement of 2 mg of folic acid" - See iHerb or Vitacost folic acid products.
• Moderate Calorie Cutbacks Fight Cancer - WebMD, 4/24/02
• Aspirin Lowers Colon Cancer Risk - Intelihealth, 4/8/02 - "A daily baby aspirin modestly reduces the risk of colon cancer by preventing the growth of ominous polyps ... the 80-milligram baby aspirin size taken daily reduces this risk by 19 percent ... the researchers found that 38 percent of those getting baby aspirin had new polyps, compared with 47 percent of people getting placeboes. However, little benefit was seen among those getting full-size aspirin. Their recurrence rate was 45 percent"
• Baby Aspirin Lowers Colon Cancer Risk - WebMD, 4/8/02
• Exposure To Sunlight Lowers Risks Of Four Cancers - Doctor's Guide, 4/4/02 - "exposure to sunlight contributes to non-melanoma skin cancer. "By contrast, several ecological studies suggest that sunlight may protect against female breast, ovarian, prostate, and colon cancer, all diseases that contribute to a substantially higher proportion of cancer mortality in the western industrialized world." ... Some studies have suggested an association between circulating vitamin D in blood, which is largely derived from sunlight, or dietary vitamin D and colorectal, prostate and female breast cancers"
• Calcium Intake May Be Associated With Reduced Risk Of Colon Cancer - Intelihealth, 3/19/02 - "Men and women who included more than 700 to 800 mg of calcium in their diets each day had a 40% to 50% lower risk of distal colon cancer compared with participants taking less than 500 mg of calcium each day"
• Boning Up on Calcium Fights Colon Cancer - WebMD, 3/19/02
• Well-Rounded Prevention May Lower Colon Cancer Risk - WebMD, 2/4/02
• Almonds Promote Colon Health - Nutrition Science News, 6/01
• Well-Rounded Prevention May Lower Colon Cancer Risk - WebMD, 2/4/02 - "Research suggests that aspirin, nonsteroidal anti-inflammatory drugs, the vitamin folate, and the mineral calcium, all may have a protective effect against colon cancer. Estrogen, too, may have a protective effect ... The best way to lower your risk of colon cancer is to reduce red meat intake, exercise regularly, stop smoking, and control your weight ... aspirin reduced the risk of colon cancer death by 40%, when taken 16 times per month or more. Similarly, the nonsteroidal anti-inflammatory drug Clinoril (sulindac) significantly reduced polyps in high-risk people. Both aspirin and Clinoril can cause stomach bleeding, but the new nonsteroidal anti-inflammatory drug Celebrex may prevent colon polyps without this side effect ... The herb rosemary, the spice turmeric, the skin of red grapes, and green tea all have similar effects as the [nonsteroidal anti-inflammatory drug] Celebrex"
• Very Low Fruit, Vegetable Consumption Produces Highest Colorectal Cancer Risk - Doctor's Guide, 4/6/01 - "Sub-analysis showed that this association was due largely to fruit consumption ... We observed no association between colorectal cancer risk and the consumption of cereal fiber, even at amounts substantially greater than previously examined"
• Canceling Cancer: New Cancer Prevention Strategies on the Horizon - WebMD, 3/26/01 - "Huerta and his team used a compound similar to vitamin D but with some different properties. Sure enough, this compound, which they call Ro 26-9114, reduced the growth of colon tumors in mice to a similar degree as regular vitamin D but without the problematic side effects"
• Calcium Pills May Stave Off Colon Cancer - WebMD, 3/9/01 - "among patients who took calcium (for one year), the size and growth of the benign tumors -- as measured by pathologists who looked at tissue biopsies -- was reduced by 58%. In contrast, only a 26% reduction was seen in patients who did not take calcium . . . The protective effect of calcium was most pronounced among the patients on a low-fat diet and taking calcium: 73% of those patients had noticeable reductions in adenomas. In contrast, there were no differences in adenoma reductions between high-fat eaters in the calcium and no-calcium groups"
• Vitamin A Reduces Risk Of Colorectal Adenoma - Doctor's Guide, 2/23/01 - "Higher serum concentrations of vitamin A, however, were significantly associated with a reduced risk of colorectal adenomas"
• Colon Cancer Prevented, Promoted by Diet - Nutrition Science News, 2/01
• Wine May Reduce the Risk of Colon Cancer, Even in Smokers - WebMD, 10/16/00
• Study: Fiber Doesn't Prevent Cancer - Intelihealth, 10/13/00 - "29 percent of those receiving the supplement (ispaghula husk, a compound similar to psyllium that is not part of the average diet) got at least one new tumor within three years. That compares with 20 percent of those given fake granules"
• Fiber May Hurt, More Than Help, in Preventing Colon Cancer - WebMD, 10/12/00
• Chemicals in apples slow cancer growth in lab tests, scientists report - CNN, 8/30/00
• Low Fat, High Fiber Doesn't Cut Colon Cancer Risk - Nutrition Science News, 8/00
• Can calcium prevent colon cancer? - Nutrition Science News, 6/00
• Preventing Colon Cancer: What You Can Do - WebMD, 4/19/00
• Estrogen Reduces Risk Of Colorectal Cancer - Doctor's Guide, 10/28/99
• Calcium Supplements Help Prevent Polyp Recurrence - Doctor's Guide, 1/14/99
• Study says calcium may cut colon cancer risk - CNN, 9/22/98
• Vitamin E May Enhance Effectiveness Of Colorectal Cancer Drug - Doctor's Guide, 11/20/97
• Vitamin Supplements May Reduce Colon Cancer Risk - Doctor's Guide, 11/6/97
• Vitamin E May Help Protect Against Colon Cancer - Doctor's Guide, 11/5/97
• Scientific Evidence On FOS Deserves Serious Attention, Nutrition Expert Says - Doctor's Guide, 5/8/97
• Research Highlights Positive Effects of Dietary Supplement NutraFlora FOS - Doctor's Guide, 12/9/96

CME:

• Doctor's Guide colorectal cancer CME courses
• Medscape colon cancer CME courses
• Medical Management of Colorectal Cancer - Medscape, 2/28/05
• Surgical Management of Colorectal Cancer - Medscape, 2/28/05
• New Treatment Options for Colorectal Cancer - Medscape, 2/24/05

General Information:

• Colon Cancer - American Academy of Family Physicians
• Colon Cancer - emedicine.com
• Colon Cancer - familydoctor.org
• Colorectal Cancer - Intelihealth
• Colon Cancer - Veritas Medicine
• Books on colon cancer - Amazon.com
• Treatments for colon cancer - Medifocus.com

Other News:

• Drug Combo Stops Recurrent Colon Polyps - WebMD, 4/15/08 - "A combination of the targeted anticancer agent DFMO and the antiarthritis drug sulindac reduces the risk of recurrent colon polyps by up to 95%"
• Road Map To Safer Pain Control Proposed; Cost Savings During Colonoscopies - Science Daily, 3/11/08
• Flat Lesions Linked to Colon Cancer - WebMD, 3/6/08
• High-dose NSAIDs May Prevent Colon Cancer - oncologystat.com. 2/5/08 - "people who took more than 2325 mg of aspirin weekly reduced colon cancer risk by 21%, compared to people who took less aspirin. Men who took 7 to 14 aspirins a week had a 28% decreased risk, and those who took more than 14 aspirins weekly had a 70% decrease in their risk of developing the disease. The advantages were only seen after 5 years of use, and taking less than 1½ pills weekly did not reduce the risk of developing the disease. The effect was also seen with the use of other NSAIDs, such as ibuprofen and naproxen"
• Smoking Can Double Risk Of Colorectal Polyps - Science Daily, 2/1/08 - "Smokers have a two-fold increased risk of developing colorectal polyps"
• Strong Link Between Obesity And Colorectal Cancer - Science Daily, 12/14/07 - "obese individuals (Body Mass Index* (BMI) >30 kg/m2) have a 20% greater risk of developing colorectal cancer compared with those of normal weight (BMI < 25 kg/m2) ... carrying even a few excess kilos substantially increases the risk of colorectal cancer; for every 5 kg weight gain the risk of developing the cancer increases by 7%"
• Diabetes May Increase Woman's Risk of Colorectal Cancer - oncologystat.com, 12/7/07 - "There was about a 50% increased risk of colorectal cancer in women with diabetes ... The researchers hypothesized that the elevated levels of insulin typically seen in people with type 2 diabetes may play a central role. Insulin stimulates the growth of normal colonic and carcinoma cells"
• PET/CT Combination Can Highly Increase Detection Of Colorectal Cancer - Science Daily, 10/29/07
• Insulin Linked to Colonic Polyps, Neoplasia - oncologystat.com, 10/23/07 - "those with poorly controlled diabetes, identified by a high serum level of hemoglobin A 1c (HbA 1c ), were significantly more likely to have advanced colonic adenomatous polyps, compared with diabetic patients with better glycemic control ... patients with poorly controlled diabetes were more than sixfold as likely to have advanced polyps and nearly sixfold as likely to have right-sided polyps, compared with patients who had better glycemic control. The average number of polyps found in poorly controlled patients was 5.5; in better-controlled patients, the average was 2.5 polyps per patient. Results from a third study reported at the meeting showed that having three or more polyps was the strongest predictor of risk for recurrent advanced neoplasia in the colon"
• The Association of Elevated HbA1c on the Behavior of Adenomatous Polyps in Patients with Type-II Diabetes Mellitus - Dig Dis Sci. 2007 Oct 16 - "colonic adenomatous polyps (APs) ... univariate analysis (UA) ... UA demonstrated that patients with poorly controlled DM-2 had a significantly increased incidence of right-sided APs (P = 0.001), a greater number of APs (P < 0.005), more advanced APs (P < 0.005), a younger age of presentation (P = 0.001), a history of smoking (P = 0.05), and greater use of exogenous insulin (P = 0.01). Logistic regression, as measured by HbA1c, demonstrated that poorly controlled DM-2 independently predicted a greater prevalence of right-sided AP, a more advanced lesion at the time of presentation, a greater number of polyps, and greater use of exogenous insulin"
• Removing Colon Polyps Cuts Death Risk - WebMD, 10/15/07 - "The researchers analyzed data on 2,602 men and women in the National Polyp Study, the landmark trial that showed that an initial colonoscopy during which the colon is cleared of precancerous polyps with regular follow-up exams significantly cut the risk of developing colon cancer by up 90% and of dying from the cancer by up to 92%"
• Obesity Ups Women’s Colon Cancer Risk - WebMD, 10/15/07 - "Obesity more than doubles a woman’s risk of developing colon cancer or growths that can lead to colon cancer"
• Interleukin-8, Key Marker For Colorectal Cancer Treatment - Science Daily, 10/9/07
• Inside Job: New Radioactive Agents For Colon Cancer Work Inside Cells - Science Daily, 10/9/07
• Low-Dose Aspirin Plus Statins Protects Against Colorectal Cancer - Medscape, 10/4/07 - "Dr. Brenner's group observed a modest risk reduction of colorectal cancer among regular users of low-dose aspirin (adjusted odds ratio = 0.77). A stronger association was found with regular use of statins (OR 0.65). The strongest risk reduction was seen in subjects who used combination low-dose aspirin and statins (OR 0.63), especially if both drugs were used for at least 5 years (OR 0.38)"
• Studies endorse 'virtual colonoscopy' - USATODAY.com, 10/4/07
• Studies Lend Insights Into Colorectal Cancer Screening - Science Daily, 10/1/07
• SCOUT Regimen Useful as First-Line Treatment for Metastatic Colorectal Cancer - Doctor's Guide, 9/26/07
• Current Chemotherapy Regimens for Advanced Colorectal Cancer Prolong Survival - Doctor's Guide, 9/21/07
• ‘Western’ Diet Tied to Colon Cancer - WebMD, 8/14/07 - "Colon cancer recurrences or death were nearly 3.5 times more common among patients who most closely followed a Western diet than among patients who followed it the least"
• Statins May Cut Colon Cancer Recurrence - Medscape, 7/26/07 - "Just 6 of 89 patients (6.7%) treated with any statin relapsed, as opposed to 43 of 269 (16%) patients with no statin use"
• Flaws In Colonoscopies May Increase Risk Of Colon Cancer - Science Daily, 5/23/07
• Cetuximab Increases Survival In Advanced Colorectal Cancer Patients - Science Daily, 4/19/07
• Colon Polyp Return Likelier in Men - WebMD, 4/16/07
• Colon Cancer Survival Linked To Number Of Lymph Nodes Examined - Science Daily, 3/22/07
• Aspirin Or NSAIDs Won't Prevent Colorectal Cancer - Science Daily, 3/20/07
• New Combined Laparoscopy and Colonoscopy Procedure May Avoid Need for Major Surgery - Doctor's Guide, 3/7/07
• Avastin Slows Colon Cancer Growth - WebMD, 1/22/07
• Lymph Node Yield Similar With Laparoscopic or Open Colectomy - Doctor's Guide, 10/20/06
• Adding Cetuximab (Erbitux) to First-Line Chemotherapy Boosts Results in Metastatic Colorectal Cancer - Doctor's Guide, 10/4/06
• FDA Approves New Colon Cancer Drug - WebMD, 9/27/06
• Chemotherapy Does Not Improve Survival in Rectal Cancer - Medscape, 9/13/06
• Study Finds That Vioxx Reduces The Risk Of Colorectal Polyps - Science Daily, 8/31/06
• FDA Approves Avastin (Bevacizumab) in Combination With Chemotherapy for Second-Line Metastatic Colorectal Cancer Patients - Doctor's Guide, 6/21/06
• Trial Demonstrates Safety of Oxaliplatin/5-FU Combination in Treating Colorectal Cancer - Doctor's Guide, 6/9/06
• Adding Cetuximab to Two Chemotherapy Regimens for Metastatic Colorectal Cancer Appears to Enhance Overall Response and Survival - Doctor's Guide, 6/6/06
• Continuous Chemotherapy No More Helpful Than Retreatment in Metastatic Colorectal Cancer - Doctor's Guide, 6/6/06
• Virtual Colonography and Optical Colonoscopy Yield Similar Screening Accuracy - Doctor's Guide, 5/24/06
• Is Colonoscopy After Age 80 Worth It? - WebMD, 5/23/06
• Women With Type 2 Diabetes at Increased Risk of Colorectal Adenomas - Doctor's Guide, 5/23/06 - "type 2 diabetics had up to a 2- to 3-fold increased risk of having any adenoma or advanced adenomas, which are precancerous polyps"
• Almost 1/3 of Colon Cancer Patients Stop Chemotherapy, Leading to Double The Death Rate - Doctor's Guide, 4/28/06
• New Drug Combination May Enhance Effectiveness of Colorectal Cancer Treatments - Doctor's Guide, 4/11/06
• Smokers, Drinkers and Men Appear to Develop Colorectal Cancer at Earlier Ages - Doctor's Guide, 3/30/06
• Antidepressants May Cut Colon Cancer - WebMD, 3/27/06
• Combination of Pemetrexed and Oxaliplatin Shows Activity in Metastatic Colorectal Cancer Patients - Doctor's Guide, 1/31/06
• Phase 2 Trial of Avastin (Bevacizumab) and FOLFIRI Produce Clinical Benefit in Most Metastatic Colorectal Cancer Patients - Doctor's Guide, 1/30/06
• Addition of Oxaliplatin to FOLFIRI Regimen Increases Survival of Patients With Metastatic Colon Cancer - Doctor's Guide, 1/30/06
• Use of Chemotherapy after Surgery for Colon Cancer Has Risen - Doctor's Guide, 12/7/05
• Many colon cancer patients under-treated - MSNBC, 12/7/05
• Molecular Advances Driving New Approaches in Colorectal Cancer Treatment - Doctor's Guide, 11/18/05
• Treatment Advances in Colorectal Cancer Often Accompanied by Toxicity Management Challenges - Doctor's Guide, 11/17/05
• New Treatment Combinations Expanding Options for Patients with Early-Stage Colorectal Cancer - Doctor's Guide, 11/17/05
• Diabetics Face Increased Risk of Colorectal Cancer - Doctor's Guide, 11/2/05 - "hyperinsulinemia and hyperglycemia promote the growth of colorectal cancer"
• Xeloda plus Oxaliplatin (Xelox) Dramatically Reduces Hospital Visits by Over 60% - Doctor's Guide, 11/2/05
• Combination Therapy with Irinotecan (CPT-11) and Pyrimidine S-1 for Inoperable Recurrent Advanced Colorectal Cancer UEGW - Doctor's Guide, 10/21/05
• Chemotherapy Plus Radiation Better in Preventing Local Recurrence of Rectal Cancer - Doctor's Guide, 10/21/05
• Dual-Drug Therapy Targets One Colon Cancer Gene - Doctor's Guide, 8/16/05
• FDA Grants Fast Track Designation for Panitumumab for Treatment of Metastatic Colorectal Cancer - Doctor's Guide, 8/1/05
• Flexible Sigmoidoscopy in Early Detection of Colorectal Cancer - Doctor's Guide, 7/7/05
• Landmark Study Shows Oral Xeloda Could Replace Standard Intravenous 5-Fu/Lv Chemotherapy - Doctor's Guide, 6/30/05
• Type 2 diabetes mellitus and the risk of colorectal cancer - Clin Gastroenterol Hepatol. 2005 Jun;3(6):587-94 - "Type 2 diabetes mellitus is associated with an increased risk of colorectal cancer"
• Revolutionary Treatment Avastin (Bevacizumab) Helps People With Advanced Colorectal Cancer Live Longer While Preserving Quality of Life - Doctor's Guide, 6/17/05
• Bevacizumab for Colorectal and Other Cancers - Medscape, 6/15/05
• FDA Approves Oral Xeloda (Capecitabine) for Adjuvant Treatment of Colon Cancer - Doctor's Guide, 6/15/05
• Chemotherapy Options Improve For Patients With Advanced Colorectal Cancer - Science Daily, 6/9/05
• Oral-Based Regimen Safe, Effective for Metastatic Colorectal Cancer - Doctor's Guide, 6/6/05
• Cholesterol Drugs May Prevent Colon Cancer - WebMD, 5/25/05 [Abstract] - "people who took cholesterol-lowering statin drugs for five years cut their colon cancer risk in half"
• Multi-National Trial Demonstrates Efficacy of Capecitabine (Xeloda) Compared With 5-Fluorouracil and Leucovorin - Doctor's Guide, 5/23/05
• Afternoon Colonoscopies Show Significantly Higher Failure Rates Than Morning Procedures - Doctor's Guide, 5/20/05
• What Colon Cancer Test Is Best for Women? - WebMD, 5/18/05
• Reduced-Dose Capecitabine Effective as First-Line Therapy in Older, Less Fit Patients With Advanced Colorectal Cancer - Doctor's Guide, 5/17/05
• Oxaliplatin Reduces Recurrence in Early-Stage Colorectal Cancer - Doctor's Guide, 5/17/05
• Wireless Capsule Endoscopy Finds More Small Bowel Polyps Than Barium Contrast Series - Doctor's Guide, 5/16/05
• 'Keyhole' Surgery Effective for Colon Cancer - WebMD, 5/12/05
• 'Virtual Colonoscopy' Effective In Finding Most Polyps But May Miss Small Ones - Science Daily, 4/23/05
• Transanal Endoscopic Microsurgery Effective on Early Rectal Cancer - Doctor's Guide, 3/7/05
• New Approach for Determining Who Should Receive Bowel Resectioning - Doctor's Guide, 3/7/05
• In Colorectal Liver Metastases, Complete Clinical Response Still Requires Surgery - Doctor's Guide, 3/7/05
• Concurrent Capecitabine With Preoperative Radiotherapy in Rectal Cancer - Doctor's Guide, 2/4/05
• Simplified Regimen May Have Higher Efficacy Than Standard Regimen for Advanced Colorectal Cancer - Doctor's Guide, 1/31/05
• 4-Year Data Show FOLFOX Maintains Disease-Free Survival Benefit for Adjuvant Colorectal Cancer Patients - Doctor's Guide, 1/31/05
• Radiation Therapy Plus Irinotecan, 5-Fluorouracil and Folinic Acid Feasible, Effective in Advanced Rectal Cancer - Doctor's Guide, 1/31/05
• Anemia Occurs Frequently in Colerectal Cancer Patients on FOLFOX Regimens - Doctor's Guide, 1/31/05
• First-Line Fluoroxuridine-Based Therapy Appears Active for Advanced Colorectal Cancer - Doctor's Guide, 1/31/05
• High-Dose Bevacizumab Plus Chemotherapy Shows Survival Benefit as Second-Line Treatment for Colorectal Cancer - Doctor's Guide, 1/28/05
• 4-Year Data Show FOLFOX Maintains Disease-Free Survival Benefit for Adjuvant Colorectal Cancer Patients - Doctor's Guide, 1/28/05
• Anaemia as a symptom of right colon cancer - Tech Coloproctol. 2004 Nov;8 Suppl 1:s62-4 - "Iron deficiency anaemia is a common symptom of right colon cancer"
• Colonoscopy Still Most Effective Colorectal Cancer Screening Method - Doctor's Guide, 1/20/05
• Colon Cancer Screening Test Called Inaccurate - WebMD, 1/18/05
• Red-Meat Eaters Risk Colon Cancer - WebMD, 1/11/05 - "Those who eat the most red meat -- beef and/or pork and/or processed meat products -- get colon cancer 30% to 40% more often than those who eat these foods only once in a while"
• Colorectal Cancer Screening Underutilized - Doctor's Guide, 1/10/05
• New Computer-Aided Detection System Detects Colon Polyps in Colons Previously Obscured by Contrast-Enhanced Fluid - Doctor's Guide, 1/5/05
• The Role of Targeted Therapies in Colorectal Cancer: An Expert Interview With Axel Grothey, MD - Medscape, 12/23/04
• Colonoscopy Best at Detecting Colon Cancer - WebMD, 12/16/04
• Bevacizumab Plus Oxaliplatin-Based Chemotherapy Prolongs Survival For Previously Treated Patients With Advanced Colorectal Cancer - Doctor's Guide, 11/29/04
• Gefitinib (Iressa) Active against Advanced Colorectal Cancer - Doctor's Guide, 11/18/04
• Xeloda (Capecitabine) Appears To Reduce Risk Of Colon Cancer Recurrence, Lessen Side Effects At Lower Cost Than Current Standard Treatment - Doctor's Guide, 11/15/04
• Bevacizumab Improves Survival Among All Colorectal Cancer Subgroups - Doctor's Guide, 11/15/04
• Panitumumab Plus Irinotecan, Fluorouracil, and Leucovorin Active as First-Line Treatment in Metastatic Colorectal Cancer - Doctor's Guide, 11/12/04
• Panitumumab Monotherapy Safe, Effective in Metastatic Colorectal Cancer - Doctor's Guide, 11/12/04
• Bevacizumab-Oxaliplatin Combination Safe in Second-Line Colorectal Cancer Treatment - Doctor's Guide, 11/12/04
• Gefitinib (Iressa) Active against Advanced Colorectal Cancer - Doctor's Guide, 11/12/04
• Oral Capecitabine Improves Disease-Free Survival as Adjuvant Colon Cancer Therapy - Doctor's Guide, 11/12/04
• Eloxatin (Oxaliplatin) Receives FDA Approval for the Treatment of Colon Cancer Following Surgery (Adjuvant Treatment) - Doctor's Guide, 11/5/04
• Staged Combination Treatment a Gentler Option for Advanced Colorectal Cancer Patients - Doctor's Guide, 11/4/04
• Ibandronate Reduces Bone Complications in Colorectal Cancer Patients With Bone Metastases - Doctor's Guide, 11/1/04
• Gout Drug Prevents Colon Cancer - WebMD, 10/18/04 - "Zyloprim reduced risk of colon cancer by two-thirds"
• Insulin May Increase Colon Cancer Risk - WebMD, 10/1/04 - "people with diabetes who had been taking insulin for three to five years had almost a threefold increase in colorectal cancer risk compared with those who did not take insulin ... The risk was even higher in people who took insulin for more than five years"
• Confocal Laser Colonoscopy May Accurately Diagnose Colorectal Cancer - Medscape, 9/29/04
• Colonoscopy Remains Most Sensitive, Best Test for Colorectal Cancer Screening - Doctor's Guide, 9/7/04
• Colonoscopy Doesn't Find All Polyps - WebMD, 9/6/04
• Virtual Colonoscopy Showing Promise as Colorectal Cancer Screening Option - Doctor's Guide, 9/1/04
• Study Shows Colonoscopy Misses 4% of Cancers - WebMD, 8/30/04
• New Colon Cancer Guideline On Chemotherapy For Stage II Colon Cancer - Doctor's Guide, 8/17/04
• Are Physicians Over-Performing Colonoscopy? - Doctor's Guide, 8/17/04
• Too Many Repeat Colonoscopies Performed - WebMD, 8/16/04
• ASCO Releases New Guideline on Chemotherapy for Stage II Colon Cancer - Doctor's Guide, 8/16/04
• Colon Cancer:  Prevention and Early Detection - Physician's Weekly, 8/9/04
• Adjuvant Chemotherapy For Colon Cancer Offers No Survival Benefit After 10 Years - Science Daily, 8/9/04
• Anastomotic Leak After Colorectal Cancer Surgery Linked to Lower Survival - Medscape, 8/6/04
• Erbitux (Cetuximab) Appears to Slow Disease Progression in Metastatic Colorectal Cancer - Doctor's Guide, 7/22/04
• Cetuximab Helpful in Irinotecan-Resistant Colon Cancer - Medscape, 7/21/04
• Current Issues in Systemic Treatment of Advanced Colorectal Carcinoma - Doctor's Guide, 7/9/04
• Bevacizumab Plus Fluorouracil-Based Chemotherapy is a New Option for Patients With Metastatic Colorectal Cancer - Doctor's Guide, 6/18/04
• Oxaliplatin Plus Fluorouracil and Leucovorin Improves Standard Adjuvant Therapy in Patients With Colon Cancer - Doctor's Guide, 6/17/04
• Oral Capecitabine (Xeloda) as Effective as Bolus 5-Fluorouracil/Leucovorin for Adjuvant Treatment of Colon Cancer - Doctor's Guide, 6/10/04
• Oral Uracil/Tegafur as Effective as Bolus 5-fluorouracil for Adjuvant Treatment of Stage II or III Colon Cancer - Doctor's Guide, 6/10/04
• Bleeding Negligible in Colorectal Cancer Patients on Anti-Coagulation and Bevacizumab Therapy - Doctor's Guide, 6/9/04
• Statin Use Appears to Reduce Risk of Colorectal Cancer - Doctor's Guide, 6/7/04
• Statin Drugs May Cut Colon Cancer Risk - WebMD, 6/7/04 - "When they added in those factors, "use of statins was still associated with a 46% reduction in risk.""
• FOLFOX4 (Oxaliplatin, Leucovorin, and Fluorouracil) Regimen Benefits Patients With Stage II Colon Cancer - Doctor's Guide, 6/6/04
• Presurgical Radiation and Chemotherapy Increased Complete Response Rate in Rectal Cancer - Doctor's Guide, 6/6/04
• Disease-Free Survival Rates Improve With the Addition of Oxaliplatin to Adjuvant Fluorouracil Plus Leucovorin for Resected Colon Cancer - Doctor's Guide, 6/3/04
• Drug That Cuts Off Tumor's Blood Supply Extends Lives Of Colorectal Cancer Patients - Science Daily, 6/3/04
• Fluorouracil-Based Chemotherapy Plus Bevacizumab Increased Survival Rates for Patients with Metastatic Colorectal Cancer - Doctor's Guide, 6/2/04
• Longer Survival With Colorectal Cancer Drugs - WebMD, 6/2/04
• Easier, Safer Colon Cancer