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Welcome to the Quality Counts. For those health conscious consumers and medical professionals that are looking to purchase nutritional supplements, vitamins, herbs, learning about medications, losing weight, health food, low carbs, high protein nutrition, and exercise, you have come to the right place. Quality Counts serves both the medical practitioner and consumer interested in nutritional therapy and alternative medicine.
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Anti-aging Research > Chromium.
Chromium
Specific Recommendations:
News & Research:
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Chromium
- Vitacost Health Library
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Chromium for Sports & Fitness
- Vitacost Health Library
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Chromium for Weight Control
- Vitacost Health Library
- Chromium - The Natural
Pharmacist
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Dangers
of Chromium? - Dr. Weil, 4/21/08 - "The possibility
of DNA damage was suggested by studies of chromium picolinate in cell cultures.
There is no evidence of such an effect in any living organism. To follow-up on
the cell culture results, researchers at New York University studied the effects
of 400 micrograms of chromium picolinate over an eight week period in 10
overweight women and found no sign of DNA damage"
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Get the diet scoop: 6 promising supplements, 6 to avoid - CNN, 2/16/07 -
"promising ...
Caffeine ... EGCG
...
Chromium ... Conjugated
Linoleic Acid (CLA) ...
5-HTP ... L-dopa or
L-tyrosine"
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Counting on Chromium Picolinate? - Dr. Weil, 2/13/07
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Research Affirms the Benefits of Combination of Chromium Picolinate and
Biotin for Improving Blood Sugar in People with Type 2 Diabetes -
Doctor's Guide, 1/8/07 - "A
significant decrease in fasting glucose levels of 4.67 mmol/L and
postprandial glucose levels of 5.77 mmol/L was seen in patients taking
chromium picolinate. The study showed that blood glucose levels continued to
improve each year throughout the six years of the study"
-
Research Affirms the Benefits of Combination of Chromium Picolinate and
Biotin for Improving Blood Sugar in People with Type 2 Diabetes -
Doctor's Guide, 12/20/06 - "The
30-day study examined 36 overweight or obese poorly controlled patients with
type 2 diabetes taking Diachrome who were already receiving oral
anti-diabetic drug(s). The results also showed a significantly greater
reduction in the total area under the curve for glucose (AUCg) during the
oral glucose tolerance test (OGTT) for the treatment group (mean change
-9.7%) compared with the placebo group (mean change +5.1%)"
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Chromium Picolinate Supplements Improve Glycemic Control - Physician's
Weekly, 11/13/06 - "Patients who
received 1,000 µg CrPic demonstrated significant improvements in insulin
sensitivity and glucose control when compared with placebo. Patients in the
CrPic arm also gained less weight (0.9 kg vs 2.2 kg) than those in the
placebo arm and had a smaller increase in body fat (0.12% vs 1.17%)"
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Chromium for Diabetes: Evidence of Benefits Grows - New Hope Natural
Media Online, 10/23/06 - "Compared
with those who took glipizide and placebo, people taking glipizide plus
chromium (500 mcg twice a day as chromium picolinate) experienced multiple
benefits, including significantly improved insulin sensitivity, less weight
gain, less abdominal fat, lower percent body fat, and lower glycohemoglobin
(an indicator of sugar-induced damage to tissues caused by diabetes)"
-
Supplementation With Chromium Picolinate Improves Glycemic Control,
Attenuates Weight Gain - Doctor's Guide, 8/9/06 -
"Blood sugar levels of study
participants taking chromium picolinate in combination with the antidiabetic
medication dropped significantly compared to the group taking the medication
plus placebo ... Study participants taking chromium picolinate also
experienced significantly lower abdominal body fat accumulation than the
group taking medication and placebo, and experienced less overall weight
gain" - See
iHerb
or
Vitacost
chromium products.
-
Chromium Improves Glycemic Control When Sulfonylurea Is Insufficient -
Medscape, 8/3/06 - "By the end of
the randomized treatment period, mean fasting glucose had decreased by 31.0
mg/dL in the CrPic group, which was significantly superior to the mean 11.3
mg/dL decrease in the placebo group ... Participants receiving placebo
gained weight and percent body fat during the randomized treatment period,
whereas subjects receiving CrPic experienced an increase in fat-free mass vs
baseline. Only subjects receiving placebo had increases in total abdominal,
visceral, and abdominal subcutaneous fat"
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Chromium supplement offers diabetes hope – animal study - Nutra USA,
2/7/06 - "Obese rats treated with
chromium picolinate had significantly improved glucose disposal rates"
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Chromium Supplementation May Reduce Carbohydrate Cravings of Atypical
Depression - Medscape, 10/6/05
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Chromium Picolinate Linked With Reduced Carbohydrate Cravings in People With
Atypical Depression - Doctor's Guide, 9/29/05 -
"65% of the chromium picolinate
patients with high carbohydrate craving versus 33% of those receiving
placebo had significantly greater improvements on total HAM-D-29 scores (p <
0.05). HAM-D-29 is a standard tool commonly used in assessing severity of
symptoms in depressed patients"
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Study Results Show Diachrome(R) Improves Poorly-Controlled Blood Sugar
Levels for People on Antidiabetic Prescription Medications - Doctor's
Guide, 9/13/05 - "Study participants
taking Diachrome with one or more antidiabetic medications saw an average
range of 0.7 - 1.9% point reduction in HbA1c levels. The study also showed
that insulin resistance was significantly reduced (P<0.05) in those taking
thiazolidinediones and Diachrome ... Diachrome is a nutritional supplement
specifically formulated for people with diabetes. It contains 600 mcg of
chromium as Chromax(R) chromium picolinate and 2 mg of biotin" - See
chromium
and
biotinat
iHerb.
-
Chromax earns another tick in the box marked 'safety' - Nutra USA,
6/27/05
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Supplemental Chromium Picolinate and Biotin Appear to Decrease Blood Glucose
and Lipid Levels in Type 2 Diabetics: Presented at ADA - Doctor's Guide,
6/17/05 - "Our most important
finding is that chromium picolinate and biotin help to decrease hemoglobin
A1c [HbA1c] values in poorly controlled diabetics ... 600 mcg chromium
picolinate and biotin 2 mg/per day" - See
chromium
and
biotinat
iHerb.
-
New Trial Shows Chromium Picolinate Reduces Weight Gain Associated with
Diabetes Medication - Doctor's Guide, 6/16/05 -
"The study participants who took
1,000 mcg of Chromax(R) chromium picolinate in combination with the
antidiabetic medication experienced significantly lower body fat
accumulation (0.12%) than the group taking medication and placebo (1.1%),
particularly in the abdomen area. The study also found those taking chromium
gained less weight"
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Chromium picolinate is best absorbed, shows study - Nutra USA, 4/5/05
- Chromium Supplementation May Not Improve Impaired Glucose Tolerance
- Medscape, 3/1/05 - "We found no
beneficial effect of chromium supplementation in the treatment of people
with
IGT
despite increases in serum chromium levels, which suggested an adequate
dosage regimen"
- Three New Studies Confirm Safety of Chromium Picolinate
- NPI Center, 11/10/04
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Novel Fiber Limits Sugar Absorption - Life Extension Magazine, 9/04 -
"Life
Extension recommends that people seeking to lose weight consume the
following supplements: ... Chromium polynicotinate 600-1000 mcg daily ...
Conjugated linoleic acid (CLA) 3000-4000 mg daily
... PGX™ highly viscous fiber blend 1000-3000 mg
5-10 minutes before each meal with 8-16 ounces of water ... Consider asking
your doctor to prescribe 500 mg two to three times daily of the
insulin-normalizing drug metformin"
- Low
Chromium Linked to Heart Disease Risk in Patients With Diabetes
- Medscape, 9/3/04 -
"Our results suggest that diabetic men with CVD have lower toenail chromium
than healthy control subjects"
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Chromium: An Element Essential to Health - Life Extension Magazine, 8/04
- "By interacting with proteins and
nucleic acids, excess glucose molecules wreak havoc with tissue elasticity
and normal function.33 Thus, controlling blood sugar may actually put the
brakes on the aging process, and should be an essential component of any
life-extension strategy"
- Chromium Picolinate Supplementation Linked With Reduced Chromium Picolinate
Supplementation Linked With Reduced Carbohydrate Cravings Associated With
Atypical Depression - Doctor's Guide, 6/2/04 - [WebMD]
"daily supplementation with 600 mcg of chromium as chromium picolinate,
significantly reduced carbohydrate cravings compared to placebo, and
improved other symptoms such as mood swings, fatigue and weight gain
perception"
-
What You Don’t Know About Blood Sugar - Life Extension Magazine, 1/04 -
"it now appears that optimal fasting blood glucose levels should probably be
under 86 mg/dL ... Chromium supplements have been shown to reduce blood
glucose significantly.70-74 The dose used in human studies ranges from 200
to 1000 mcg of elemental chromium a day, with best results occurring when
400 mcg or more of chromium is taken daily"
-
The Chromium Connection - Natural Foods Merchandiser, 9/03 -
"The body requires certain nutrients to control glucose metabolism,
especially chromium, zinc
and vitamins B and C
... Diabetes is devastating because of its
consequences. The condition often leads to hypertension, lipid disorders,
cardiovascular disease, blindness, skin problems, nerve damage, kidney
disorders and loss of limbs. Although it appears chromium picolinate may
benefit your customers with type 2 diabetes, supplementation represents just
one facet of treatment"
- Chromium Supplements Appear to Improve Glucose Sensitivity in Diabetics
- Medscape, 8/29/03 - "We think that
chromium picolinate can influence a person's
diabetic treatment so that levels of insulin required may be reduced ...
HbA1c levels decreased from 9.5% to 9% during a six-month period in patients
receiving a higher dose of the supplement, a difference that was
statistically significant ... The study also showed a significant reduction
in cholesterol levels and trends for improvement in triglycerides in both
chromium picolinate groups as well as a reduction in blood pressure in all
groups"
- Chromium Effective for Common Type of Depression -
New Hope Natural Media, 4/10/03 -
"15 people suffering from atypical depression,
who had been off of antidepressant medication for at least seven days, were
randomly assigned to receive chromium picolinate or a placebo for eight
weeks. The dose was 400 mcg per day for the first two weeks, then 600 mcg
per day for the remainder of the study ... Seventy percent (7 of 10) of
those receiving chromium responded to the treatment, whereas none of the
five individuals in the placebo group had a positive response. Although the
number of participants in the study was small, the difference in outcome
between the chromium and placebo groups was highly statistically
significant. Moreover, in 60% of those receiving chromium, the depression
went into remission"
-
Chromium For Insulin Function - Functional Foods & Nutraceuticals, 1/03
-
EU And US Split Over Chromium - Functional Foods & Nutraceuticals, 1/03
-
Octacosanol Beats Statins - Dr. Janson, 4/02 -
"Chromium supplements in the range of 200 to 400 mcg daily reduce total
cholesterol and raise HDL levels, and up to 1000 mcg also help control blood
sugar levels"
- Could Chromium Picolinate Cause Cancer? - WebMD,
12/11/01
- Can a Mix of Chromium and Biotin Help Diabetics Control Blood Sugar?
- WebMD, 10/15/01 - "when chromium
and biotin are present together, they have more of a response than what
would be expected by adding their effects separately. "As soon as you put
those two together, you get a much greater increase in glucose metabolism,""
-
A Dose of Chromium - Nutrition Science
News, 4/99
- Chromax
Effective For Steroid-Induced Diabetes Treatment - Doctor's Guide,
3/26/99
-
Chromium Steels the Body Against Diabetes - Nutrition Science News, 2/99
- Study
Confirms That Chromium Picolinate Aids In Body Fat Loss
- Doctor's Guide, 6/23/98
- Chromium
Picolinate Supplements Help Control Diabetes -
Doctor's Guide, 11/4/97
- Chromium May
Help Obese People Avoid Diabetes - Doctor's Guide, 6/30/97
Abstracts:
-
Phenotype of subjects with type 2 diabetes mellitus may determine clinical
response to chromium supplementation - Metabolism. 2007
Dec;56(12):1652-5 - "Sixty-three percent of the
subjects with type 2 diabetes mellitus responded to the Cr treatment as
compared with 30% with placebo ... Subject phenotype appears to be very
important when assessing the clinical response to Cr because baseline
insulin sensitivity was found to account for nearly 40% of the variance in
the clinical response to Cr"
-
Effect of Chromium Supplementation on Glucose Metabolism and Lipids: A
Systematic Review of Randomized Controlled Trials - Diabetes Care. 2007
May 22 - "There was no benefit in
individuals without diabetes ... Chromium supplementation significantly
improved glycemia among patients with diabetes"
-
The Effect of Chromium Picolinate and Biotin Supplementation on Glycemic
Control in Poorly Controlled Patients with Type 2 Diabetes Mellitus: A
Placebo-Controlled, Double-Blinded, Randomized Trial - Diabetes Technol
Ther. 2006 Dec;8(6):636-643 -
"randomized to receive 600 microg of chromium as chromium picolinate and
biotin (2 mg/day) ... supplementation with a combination of chromium
picolinate and biotin in poorly controlled patients with diabetes receiving
antidiabetic therapy improved glucose management and several lipid
measurements. Chromium picolinate/ biotin supplementation may represent an
effective adjunctive nutritional therapy to people with poorly controlled
diabetes with the potential for improving lipid metabolism"
-
Chromium picolinate supplementation attenuates body weight gain and
increases insulin sensitivity in subjects with type 2 diabetes -
Diabetes Care. 2006 Aug;29(8):1826-32 -
"1,000 mug Cr as CrPic ... CrPic
supplementation in subjects with type 2 diabetes who are taking sulfonylurea
agents significantly improves insulin sensitivity and glucose control.
Further, CrPic supplementation significantly attenuated body weight gain and
visceral fat accumulation compared with the placebo group" - See
iHerb
or
Vitacost
chromium products.
-
The influence of chromium chloride-containing milk to glycemic control of
patients with type 2 diabetes mellitus: a randomized, double-blind,
placebo-controlled trial - Metabolism. 2006 Jul;55(7):923-7 -
"one group to receive
chromium-containing milk powder (chromium 200 mug/20 g milk powder) and the
other to receive placebo twice a day for 16 weeks ... The chromium group
demonstrated a lower FPG and fasting insulin (-38.1 +/- 9.2 vs 63 +/- 8. 5
mg/dL and -1.7 +/- 0.2 vs 1.9 +/- 0.3 muU/mL, respectively"
-
Effect of chromium on the insulin resistance in patients with type II
diabetes mellitus - Folia Med (Plovdiv). 2005;47(3-4):59-62 -
"We found a significant decrease of
the immune-reactive insulin and the insulin resistance index after a
two-month application of chromium 30 microg daily (1 tablet of chrome
picolinate) ... Chromium included early in the complex therapy of diabetes
is beneficial in the reduction of the degree of insulin resistance"
-
Effect of chromium supplementation on blood glucose and lipid
levels in type 2 diabetes mellitus elderly patients
- Int J Vitam Nutr Res. 2004 May;74(3):178-82 -
"study group received 200 microg of chromium twice a day for a three-week
period ... Significant differences in the fasting blood level of glucose
compared to the baseline (190 mg/dL vs 150 mg/dL, p < 0.001) were found at
the end of the study. HbA1c also improved from 8.2% to 7.6% (p < 0.01).
Total cholesterol was also reduced from 235 mg/dL to 213 mg/dL (p < 0.02). A
trend towards lowered triglyceride levels was also observed (152 mg/dL vs
136 mg/dL)"
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