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Anti-aging Research > Cayenne/Capsicum (Capsicum frutescens).
Cayenne/Capsicum (Capsicum frutescens)
News & Research:
pepper compound could help hearts - Science Daily, 3/27/12 -
"The team found, for instance, that capsaicin and a
close chemical relative boost heart health in two ways. They lower cholesterol
levels by reducing accumulation of cholesterol in the body and increasing its
breakdown and excretion in the feces. They also block action of a gene that
makes arteries contract, restricting the flow of blood to the heart and other
organs. The blocking action allows more blood to flow through blood vessels"
peppers may come with blood pressure benefits - Science Daily, 8/3/10 -
found that long-term dietary consumption of capsaicin, one of the most abundant
components in chili peppers, could reduce blood pressure in genetically
evidence that chili pepper ingredient fights fat - Science Daily, 6/2/10
- "The capsaicin-treated rats lost 8 percent of
their body weight and showed changes in levels of at least 20 key proteins
found in fat. The altered proteins work to break down fats. "These changes
provide valuable new molecular insights into the mechanism of the
antiobesity effects of capsaicin,""
Chilli extract may prevent obesity complications: Study - Nutra USA,
pain relievers - MSNBC, 9/14/08 - "Capsaicin:
For arthritis, shingles, or neuropathy ... InflaThera or Zyflamend: For
arthritis ... Aquamin: For osteoarthritis ... SAM-e (S adenosylmethionine):
For osteoarthritis ... Fish oil: For joint pain from arthritis or autoimmune
disorders ... Methylsulfonyl-methane (MSM): For osteoarthritis"
Fiery Pepper Fatal for Fat Cells? - WebMD, 3/6/07
Pepper: Hot Stuff For Fighting Fat? - Science Daily, 3/5/07
3 Herbal Medicines
May Ease Back Pain - WebMD, 4/18/06 -
"A 60-milligram daily dose of
devil's claw also appeared to cut back pain as much as a 12.5-milligram
daily dose of Vioxx, a painkiller no longer on the market due to a rise in
the risk of cardiovascular events -- such as heart attack and stroke -- in
Pepper Component Hot Enough To Trigger Suicide In Prostate Cancer Cells
- Science Daily, 3/19/06 - "Capsaicin induced approximately 80 percent of prostate cancer cells growing
in mice to follow the molecular pathways leading to apoptosis. Prostate
cancer tumors treated with capsaicin were about one-fifth the size of tumors
in non-treated mice"
Spicy Spin on Treating Prostate Cancer - WebMD, 3/15/06 -
"Capsaicin prompted cancer cells to
die and curbed tumor growth ... Capsaicin was also linked to lower levels of
prostate specific antigen (PSA)"
Pepper extract could stop prostate cancer growth - Nutra USA, 3/15/06 -
"capsaicin has a profound inhibiting
effect on the growth of prostate cancer cells in vitro and in vivo ,
inducing apoptosis [programmed cell death] of prostate cancer cell lines"
Fiery Hot Therapy
Improves Asthma - WebMD, 5/25/04
- Topical Capsaicin Confers Moderate to Poor Pain Reduction for Neuropathic
and Musculoskeletal Disorders - Doctor's Guide,
- Capsaicin Patch Eases Postherpetic Neuralgia Pain
- Medscape, 4/3/03
- Women Rate Capsaicin Pain Stimulus as More Intense than Men
- Doctor's Guide, 8/22/02
- Topical Capsaicin 0.075 Percent Best Choice For Double Blinded Studies
- Doctor's Guide, 8/21/02
Cayenne Is A Hot Therapeutic Ticket - Functional Foods & Nutraceuticals,
Antitumor Activity of Capsaicin on Human Colon Cancer Cells in Vitro and
Colo 205 Tumor Xenografts in Vivo - J Agric Food Chem. 2010 Nov 17 -
"capsaicin induced cytotoxic effects in a time- and
dose-dependent manner and increased reactive oxygen species (ROS) and Ca(2+)
but decreased the level of mitochondrial membrane potential (ΔΨ(m)) in colo
205 cells. Data from Western blotting analysis indicated that the levels of
Fas, cytochrome c, and caspases were increased, leading to cell apoptosis.
Capsaicin decreased the levels of anti-apoptotic proteins such as Bcl-2 and
increased the levels of pro-apoptotic proteins such as Bax.
Capsaicin-induced apoptosis in colo 205 cells was also done through the
activations of caspase-8, -9 and -3. In vivo studies in immunodeficient
nu/nu mice bearing colo 205 tumor xenografts showed that capsaicin
effectively inhibited tumor growth. The potent in vitro and in vivo
antitumor activities of capsaicin suggest that capsaicin might be developed
for the treatment of human colon cancer"