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Anti-aging Research > Calcium.
Calcium
Specific Recommendations:
CME:
-
Minerals for Good Health - The University of Mississippi School of
Pharmacy, exp. 12/31/02
News & Research:
- Why you need to go with a supplement with the right
calcium, magnesium, zinc, copper ratio:
-
Magnesium--A Forgotten Mineral - Health &
Nutrition Breakthroughs, 9/97 -
"Excess calcium and phosphate also interfere with magnesium absorption.
(Thus, taking calcium supplements without adding magnesium could result in
magnesium deficiency.)"
-
Inhibitory effects of zinc on magnesium balance and magnesium absorption in
man - J Am Coll Nutr. 1994 Oct;13(5):479-84 -
"the overall effect of the high Zn intake of the three groups combined,
regardless of the Ca intake, was a highly significant decrease of Mg
absorption and of the Mg balance"
-
Zinc -- The Immune System's Missing Link? - Health & Nutrition
Breakthroughs, 12/97 -
"Supplementing with zinc is quite safe--its only significant side effect is
lowered copper levels in the body tissues, since the two minerals compete
for absorption. Considering zinc's safety, people should consider taking
zinc supplements, especially as they age--being sure to include copper in
the proper balance. Most practitioners who supplement their patients' diets
with zinc also recommend taking copper at a ratio of 10 mg to 15 mg zinc for
each milligram of copper."
-
Drugs That Deplete- Nutrients That Heal - Life Extension Magazine, 7/00
- "The irony here is that excess
calcium supplementation may lead to magnesium deficiency (it also interferes
with zinc and iron absorption)."
-
Calcium, Keep What You Take - Life Extension Magazine, 3/99 -
"The final study was a two-year, placebo controlled trial on 225
postmenopausal women. One group received calcium supplements only, the
second group zinc, manganese and copper, the third group received calcium
plus zinc, manganese and copper, while the fourth group received a placebo.
After two years, the only group who experienced an improvement in bone
mineral density was the group taking calcium plus zinc, manganese and
copper" - [Abstract]
- Magnesium: The Multi-Purpose Mineral - Think
Muscle Newsletter -
"If you take high amounts of calcium daily, you may have a magnesium
deficiency. Most experts suggest that your calcium: magnesium ration should
be 2:1. In other words, if you take 1500 mg of calcium daily through diet
and supplementation, you should try to consume at least 750 mg of magnesium
daily as well"
-
Risk of
endometrial cancer in relation to individual nutrients from diet and supplements
- Public Health Nutr. 2011 Jul 14:1-13 - "endometrial
cancer (EC) ... There existed little evidence of an association with EC for the
majority of macronutrients and micronutrients examined. We observed a
statistically significant increased risk associated with the highest, compared
with the lowest, quartile of intake of dietary cholesterol
(multivariable-adjusted OR = 1·51, 95 % CI 1·08, 2·11; P for trend = 0·02).
Age-adjusted risk at the highest level of intake was significantly reduced for
Ca from food sources (OR = 0·73, 95 % CI 0·54, 0·99) but was attenuated in the
multivariable model (OR = 0·82, 95 % CI 0·59, 1·13). When intake from
supplements was included in Ca intake, risk was significantly reduced by 28 %
with higher Ca (multivariable-adjusted OR = 0·72, 95 % CI 0·51, 0·99, P for
trend = 0·04). We also observed unexpected increased risks at limited levels of
intakes of dietary soluble fibre, vitamin C, thiamin, vitamin B6 and lutein/zeaxanthin,
with no evidence for linear trend"
-
Citrate key in bone's nanostructure - Science Daily, 6/8/11 -
"At this
point, we feel that citrate probably also has a role in the biomineralization of
the apatite ... It's also been noted in the literature that as an organism ages,
the nanocrystal thickness increases and the citrate concentration goes down ...
"and there's also support from clinical studies that citrate is good for bones,"
adding that one of the leading supplements for bone strength contains calcium
citrate ... While calcium loss is a major symptom in osteoporosis, the decline
of citrate concentration may also contribute to bone brittleness" - Note:
I read a long time ago that the citrate form of most minerals was absorbed
better and have been using that form for some time. For example, see the
magnesium citrate in
Jarrow Formulas, Magnesium Optimizer Citrate, 100 Easy-Solv Tablets at iHerb.

-
Increasing daily calcium will not reduce the risk of fractures in later life,
study suggests - Science Daily, 5/24/11 - "women had
the lowest risk of having a fracture when they consumed around 750 mg a day of
calcium. However, the fracture risk in women who started to increase their
calcium intake over time did not decrease ... while low levels of calcium intake
(less than 700 mg per day) increase the risk of fractures and osteoporosis,
there is no need to start increasing calcium intake above the amount. Increases
did not further reduce the fracture and osteoporosis risk"
-
Before
you start bone-building meds, try dietary calcium and supplements, experts urge
- Science Daily, 5/2/11 - "For many people, prescription
bone-building medicines should be a last resort ... adults who increase their
intake of calcium and vitamin D usually increase bone mineral density and reduce
the risk for hip fracture significantly ... I suspect that many doctors reach
for their prescription pads because they believe it's unlikely that people will
change their diets ... prescription bone-building medications are expensive, and
many have side effects, including ironically an increase in hip fractures and
jaw necrosis. They should be used only if diet and supplements don't do the
trick ... For bone health, the researchers also encourage consuming adequate
protein, less sodium, and more magnesium and potassium"
-
Report
sets new dietary intake levels for calcium and vitamin D to maintain health and
avoid risks associated with excess - Science Daily, 12/1/10 -
"The science on calcium's role in bone health shows that
700 milligrams per day meets the needs of almost all children ages 1 through 3,
and 1,000 milligrams daily is appropriate for almost all children ages 4 through
8. Adolescents ages 9 through 18 require no more than 1,300 milligrams per day.
For practically all adults ages 19 through 50 and for men until age 71, 1,000
milligrams covers daily calcium needs. Women starting at age 51 and both men and
women age 71 and older need no more than 1,200 milligrams per day ... As for
vitamin D, 600 IUs daily meets the needs of almost everyone in the United States
and Canada, although people 71 and older may require as much as 800 IUs per day
because of potential physical and behavioral changes related to aging"
-
Industry : Calcium research “cherry picked” results - Nutra USA, 7/30/10
-
Calcium
supplements play an important role in maintaining bone health, experts say -
Science Daily, 7/29/10 - "The authors of the
meta-analysis examined the effects of calcium supplements on the risk of
cardiovascular events, concluding there is an increased risk, and calling for a
reassessment of the role of calcium supplements for osteoporosis. According to
CRN, these conclusions are dramatically overstated, considering the limitations
of meta-analysis, in general, and this meta-analysis, specifically ... The
authors characterize these findings as though all of the selected studies
suggest increased risk. In fact, the opposite is true: most of the studies do
not suggest increased risk ... these researchers are making sweeping judgments
about the value of calcium supplements by only assessing a handful of handpicked
studies ..."
-
Calcium
supplements linked to increased risk of heart attack, study finds - Science
Daily, 7/29/10 - "calcium supplements were associated
with about a 30% increased risk of heart attack and smaller, non-significant,
increases in the risk of stroke and mortality"
-
Low
calcium intake linked with increased risk of osteoporosis and hypertension in
postmenopausal women - Science Daily, 6/18/10 - "a
significantly increased proportion of women (35.4%) who consumed a lower amount
of calcium through intake from dairy sources, had a concurrent diagnosis of both
hypertension and osteoporosis, compared with women who consumed a higher amount
of calcium (19.3% p<0.001) ... Further statistical analyses revealed that a
lower calcium intake was associated with an increased risk of developing
hypertension or osteoporosis over time when compared with controls (Odds Ratio
(OR) hypertension: 1.43; 95%CI: 1.12-1.82, osteoporosis: OR 1.46; CI:
1.15-1.85). Women who consumed a lower amount of calcium were shown to be most
likely to develop both conditions over time compared with women consuming a
higher amount of calcium (OR 1.60; CI: 1.09-2.34)"
-
Calcium
supplements: Too much of a good thing? - Science Daily, 6/1/10 -
"The incidence of the so-called milk-alkali or
calcium-alkali syndrome is growing in large part because of widespread use of
over-the-counter calcium and vitamin D supplements ... the obvious preventive
strategy against the calcium-alkali syndrome is to limit the intake of calcium
to no more than 1.2 to 1.5 grams per day. "Calcium supplements taken in the
recommended amounts are not only safe but are quite beneficial. Taken to excess
is the problem""
-
Calcium
consumption may cause prostate cancer in Chinese, research suggests -
Science Daily, 6/1/10 - "Results showed a 25 percent
increased risk of prostate cancer when comparing those who consumed, on average,
659 mg vs. 211 mg of total calcium a day ... Major food sources of calcium in
this population consisted of: vegetables (19.3 percent), dairy (17.3 percent),
grain products (14.7 percent), soyfoods (11.8 percent), fruit (7.3 percent) and
fish (6.2 percent). However, the researchers stress that there was no positive
association with prostate cancer risk and any one particular food source ...
Among men with less than average BMI (median BMI was 22.9 kg/m2), the
researchers found a twofold increased risk of prostate cancer"
-
Calcium
in early life may prevent obesity later - Science Daily, 5/13/10 -
"not getting enough calcium in the earliest days of life
could have a more profound, lifelong impact on bone health and perhaps even
obesity than previously thought"
-
High calcium intakes may improve male survival: Study - Nutra USA, 2/25/10 -
"The highest average intakes, almost double the
recommended levels, were associated with a 25 per cent reduction in so-called
all-cause mortality, compared with the lowest average intakes" - [Abstract]
-
Benefits
of calcium and vitamin D in preventing fractures confirmed - Science Daily,
1/14/10 - "both calcium and vitamin D supplements on a
daily basis reduces the risk of bone fractures, regardless of whether a person
is young or old, male or female, or has had fractures in the past, a large study
of nearly 70,000 patients from throughout the United States and Europe has
found" - See
vitamin D products at iHerb
.
-
High
Calcium Level In Arteries May Signal Serious Heart Attack Risk - Science
Daily, 7/28/09
-
Diabetics On High-fiber Diets Might Need Extra Calcium - Science Daily,
3/24/09 - "Our new findings suggest that dietary fiber
reduces the body's capacity to absorb calcium"
-
Calcium May Cut Cancer Risk - WebMD, 2/23/09 -
"older men and women who got the most calcium from food and supplements had a
16% lower risk of colorectal and other cancers of the digestive system than
those who got the least calcium"
-
Calcium
May Only Protect Against Colorectal Cancer In Presence Of Magnesium -
Science Daily, 11/16/08 - "supplementation of calcium
only reduced the risk of adenoma recurrence if the ratio of calcium to magnesium
was low and remained low during treatment. "The risk of colorectal cancer
adenoma recurrence was reduced by 32 percent among those with baseline calcium
to magnesium ratio below the median in comparison to no reduction for those
above the median"
-
Too Much
Calcium In Blood May Increase Risk Of Fatal Prostate Cancer - Science Daily,
9/3/08 - "Comparing men in the top third with men in the
bottom third, we found a significantly increased hazard for fatal prostate
cancer"
-
Calcium
With or Without Vitamin D May Help Prevent Osteoporosis - Medscape, 8/27/08
- "For best therapeutic effect, we recommend minimum
doses of 1200 mg of calcium, and 800 IU of vitamin D (for combined calcium plus
vitamin D supplementation)"
-
Calcium
Alone Does Not Reduce Hip Fracture Risk - Science Daily, 6/29/08 -
"a recent analysis of several studies found no reduction
in risk of hip fracture with calcium supplementation ... Future studies of
fracture prevention should focus on the best combination of calcium plus vitamin
D, rather than on calcium supplementation alone"
-
Vitamin
D And Calcium Influence Cell Death In The Colon, Researchers Find - Science
Daily, 4/13/08 - "We were pleased that the effects of
calcium and vitamin D were visible enough in this small study to be significant
and reportable"
-
Calcium: Heart Risk for Older Women? - WebMD, 1/15/08 -
"The women in the supplement group got 861 milligrams of
calcium from diet per day, on average, boosting their total daily intake to
1,861. The placebo group averaged about 853 milligrams of calcium daily from
their diet ... The risk of a heart attack was about 1.5 times greater for those
in the supplement group, but the link did not reach statistical significance ...
the calcium supplements may elevate blood calcium levels and possibly speed
calcification in blood vessels"
-
Calcium
In Coronary Arteries May Be Linked To Increased Risk For Heart Disease In
Low-risk Women - Science Daily, 12/12/07
-
Can Calcium & Vitamin D Reduce Diabetes Risk? - Physician's Weekly, 11/19/07
- "found a relatively consistent association between low
vitamin D status, calcium or dairy intake, and prevalent type 2 diabetes based
on the utilization of vitamin D and/or calcium supplementation ... a combination
of vitamin D and calcium supplements may play a role in type 2 diabetes
prevention particularly in high-risk populations"
-
Low Calcium May Spur Breast Cancer Spread - oncologystat.com, 10/19/07 -
"The study involved implanting breast cancer cells into
mice and feeding them a low-calcium diet. The mice experienced a high bone
turnover and showed a 43% increase in bone destruction, a 24% increase in tumor
area, and a 24% increase in tumor cell proliferation compared to a control
group"
-
Calcium Supplements Thwart Bone Loss - WebMD, 8/23/07 -
"For best therapeutic effect, we recommend minimum doses
of 1200 milligrams [mg] of calcium, and 800 IU [international units] of vitamin
D (for combined calcium plus vitamin D supplementation)"
-
The Effect of High Calcium Levels on Prostate Cancer - Physician's Weekly,
8/13/07 - "the relative risk of prostate cancer for
2,000 mg/day or more of calcium intake was 1.63. Conversely, a 1.26 relative
risk calculation was observed for ingestion of less than 1,000 mg/day of
calcium"
-
National Osteoporosis Foundation's Updated Recommendations for Calcium and
Vitamin D3 Intake - Doctor's Guide, 7/16/07 -
"adults aged 50 years and older should have 1200 mg of calcium/day and 800 to
1,000 I.U. of vitamin D3/day"
-
Cancer Benefit From Vitamin D? - WebMD, 6/8/07 -
"Women in the four-year study took 1,500
milligrams of calcium supplementation either alone or with 1,100 International
Units (IU) of vitamin D each day ... women who took both supplements wound up
with nearly 60% less risk of cancers at the end of the study compared with women
who took placebo" -
Vitamin D products at iHerb
.
-
Calcium/Vitamin D Slows Weight Gain - WebMD, 5/14/07 -
"Half the women took 1,000 milligrams of
calcium and 400 international units (IU) of vitamin D every day ... Women not
taking enough calcium were getting the greatest benefit. They were 11% less
likely to gain weight and more likely to remain weight-stable or lose weight"
-
High
Calcium And Vitamin D Intakes Associated WIth Higher Risk Of Cognitive
Impairment In Elderly - Science Daily, 5/1/07 -
"we do not know if high calcium and
vitamin D intake are involved with the causation of brain lesions, but the study
provides support to the growing number of researchers who are concerned about
the effects of too much calcium, particularly among older adults, given the
current emphasis on promoting high intakes of calcium and vitamin D"
-
Calcium
Lowers Cardiovascular Risk In People On A Weight Loss Program, Study Finds -
Science Daily, 2/14/07 - "In addition to
the low-calorie diet, participants were given daily tablets containing either a
placebo or 1,200 mg of calcium with vitamin D "to facilitate calcium
absorption," adds Dr. Tremblay. At the end of the 15-week period, researchers
observed greater drops in LDL (bad cholesterol) and increases in HDL (good
cholesterol) in the calcium-plus-vitamin D group than in the placebo group"
-
Calcium May Reduce Colon Cancer Risk - WebMD, 1/16/07 -
"Patients with a history of nonmalignant
polyps took either 1,200 milligrams of calcium in supplement form or a placebo
daily for four years ... Calcium use was associated with a 17% lower relative
risk for polyp recurrence"
-
Updated Position Statement for Calcium Intake in Postmenopausal Women -
Medscape, 11/20/06 - "The recommended
calcium requirement is 1000 mg daily for premenopausal women aged 25 to 50
years, and varies from 1200 to 1500 mg daily for postmenopausal women according
to different organizations (National Institutes of Health, Institute of
Medicine, and Osteoporosis Society of Canada)"
-
Calcium again linked to lower colorectal cancer risk - Nutra USA, 11/8/06 -
"the relative risk of colorectal cancer
for the highest calcium intake group was 40 per cent lower compared to the
lowest intake group"
-
Extra Calcium May Prevent Hypertension Problems in Pregnant Women - Doctor's
Guide, 7/21/06 - "Expectant mothers may
be able to prevent potentially serious medical problems in themselves and their
babies simply by boosting their daily calcium intake"
-
Dairy Foods May Help Prevent Diabetes - WebMD, 7/11/06 -
"each additional daily dairy serving was
associated with a 4% drop in diabetes risk ... Women with the highest dietary
calcium intake were about 20% less likely to be diagnosed with type 2 diabetes
than the ones who consumed the least amount of calcium ... the findings were
stronger for low-fat dairy products than for high-fat dairy items"
-
Calcium
May Curb Middle-Aged Spread - WebMD, 6/30/06 -
"of 5,341 women aged 53 to 57, those
taking at least 500 milligrams of calcium each day gained about 11 pounds after
age 45, compared to 15 pounds for those who didn't take the supplements"
-
New
Research Clarifies Roles Of Calcium, Vitamin D, And Protein In Bone Health,
Fracture Risk - Science Daily, 6/6/06
-
5 things you need
to know about calcium - MSNBC, 5/26/06 -
"You may need more vitamin D. Current
federal recommendations for adults aged 51 to 70 still call for the 400 IU daily
used in these studies. Yet research now shows that 700 to 1,000 IU of vitamin D
a day appears necessary to reach the most healthy blood levels of vitamin D. A
daily intake of 400 IU is now considered inadequate to prevent fractures"
-
Large Survey Finds Average Calcium Use Too Low Among Osteoporotic Women -
Doctor's Guide, 5/2/06 - "the average
daily intake of calcium among women was 660 mg/day, while the Continuing Survey
of Food Intake by Individuals (CFII) between 1994 and 1996 found that 90% of
women over 50 years consume less than the reference 1200 mg/day"
-
Calcium, vitamin D may lower diabetes risk - Nutra USA, 4/3/06 -
"A combined daily intake of more than
1,200 milligrams of calcium and more than 800 international units (IU) of
vitamin D was associated with a 33 per cent lower risk of type-2 diabetes"
-
Role and
Importance of Calcium in Preventing and Managing Osteoporosis - Medscape,
3/30/06 - "Although very high calcium
intakes can overcome much of the absorptive block of vitamin D deficiency, the
amounts needed are considerably in excess of calcium supplement doses used in
most trials.[38] Therefore, unrecognized vitamin D deficiency will also confound
a trial of calcium. This is not merely a theoretical concern. Various
population-based studies indicate that prevalence of inadequate vitamin D status
is high,[39] and in some groups nearly universal"
-
Bone
Supplements (Calcium and Vitamin D) review - ConsumerLab.com, 3/3/06 -
"one product failed testing for
containing 3.5 mcg of lead per daily serving"
-
Vitamin D, calcium supplements could reduce falls in women, not men - Nutra
USA, 2/28/06 - "700 IU of cholocalciferol (vitamin D3) plus 500 mg of calcium in the form of calcium
citrate malate ... After three years of supplementation the researchers
observed: “Long-term dietary cholocalciferol-calcium supplementation reduces the
odds of falling in ambulatory (mobile) older women by 46 per cent, and
especially in non-active women by 65 per cent.”"
-
Calcium
Plus Vitamin-D Supplementation Does An Older Body Good - Science Daily,
2/24/06 - "The older the woman, the more
likely it is that consistent use of calcium and vitamin-D supplements will play
a role in reducing her risk for osteoporosis"
-
Calcium and Vitamin D Supplements Offer Modest Bone Improvements, No Benefits
for Colorectal Cancer - Doctor's Guide, 2/16/06 -
"women who consistently took the full
supplement dose experienced a significant 29% decrease in hip fracture ... 1000
milligrams of calcium carbonate combined with 400 IUs of vitamin D3"
-
I'm not
sure if they used enough vitamin D in this study plus why didn't they include
magnesium and silicon plus why did the use the carbonate form of calcium when
the citrate form is 2.5 times more bioavailable? It's almost like they
designed the study to fail. See:
-
Vitamin D Does Prevent Fractures in Elderly - HealthDay, 5/10/05
- "If someone did not have a
fracture yet, I would recommend 700 to 800 International Units (IU) of
vitamin D a day, with at least 700 milligrams of calcium ... If you have had
a fracture, you should discuss with your physician whether you may need
more. The National Science Foundation says the safe upper limit is 2,000
units a day, so you can go to 1,500 units or higher, especially if you live
in a country like the United Kingdom, where you have little exposure to
sunlight"
-
Vitamin D:
Important for Prevention of Osteoporosis, Cardiovascular Heart Disease, Type
1 Diabetes, Autoimmune Diseases, and Some Cancers - Medscape, 11/11/05 -
"A multivitamin
containing 400 IU of vitamin D is inadequate to satisfy the body's
requirement.[32] It is estimated that at least 1,000 IU of vitamin D per day
is needed to satisfy the body's requirement"
- Calcium Supplements: Benefits and Risks -
Medscape, 1/26/05 - "Perhaps the most effective method of preventing osteoporosis
is ingestion of adequate calcium. Experts suggest the daily requirement for
calcium is 1,300 mg for people ages 9 to 18, 1,000 to 1,200 mg for adults 19
to 50, and 1,500 mg for people over 50 ... You should take only the amount
of calcium recommended. Ingesting high doses of calcium each day can be
harmful and can cause kidney stones"
-
A Deficiency of D? - WshingtonPost.com, 4/5/05 -
"most adults, especially those over
50, fall short on recommended daily levels of vitamin D, an essential
nutrient long known to preserve bones and now increasingly tied to
protection against ailments from cancer to rheumatoid arthritis ... the most
practical way to increase our vitamin D levels is from supplements ... a
growing number of scientists believe that vitamin D intake should be at
least 1,000 IU or higher"
-
Dietary Magnesium Could Lead to Stronger Bones
- Doctor's Guide, 12/21/05 -
"For every 100 milligram per day
increase in magnesium intake, data showed a 1% increase in bone density ...
this link was only true for the older white men and women"
-
Silicon May Play Important Role in Bone Health - Doctor's Guide, 9/27/05
- "Silicon, taken as
choline-stabilized orthosilicic acid (ch-OSA) supplementation, might help
improve bone health and type I collagen synthesis ... the benefits were
especially apparent when evaluating changes in PINP, the most sensitive bone
formation marker, and resulted in significant improvements after 12 months
amongst the subjects in the six and 12 mg silicon groups"
- See
Jarrow BioSil at iHerb
.
- Life Extension Foundation Newsletter - 2/18/06 -
"The dosage of vitamin D in this
study was 400 international units, an amount determined to be too low to
maintain optimal serum levels of the vitamin in other research.
Additionally, the form of calcium used was calcium carbonate, which is
commonly sold as an antacid and is not known to be one of better absorbed
forms of the mineral"
-
Calcium Citrate Shown to Have Superior Bioavailability and Protects Against
Bone Loss - Medscape, 11/21/00 -
"the calcium supplement formulation calcium citrate was 2.5 times more
bioavailable than calcium carbonate, even when given with a meal, the
optimum method of ensuring calcium carbonate absorption"
- See Body Wise
Essential Calcium.
It contains calcium citrate, magnesium, boron, silica and more.
- Counting on
Calcium? - Dr. Weil, 4/24/06
-
US teens not getting sufficient calcium - Nutra USA, 2/6/06 -
"The article, published in the
journal Pediatrics (Vol. 117, pp. 578-585), reported that about 30 per cent
of boys and only 10 per cent of girls were achieving the recommended daily
intake (RDI) of calcium" - [WebMD]
-
Eat Dairy Foods,
Avoid Breast Cancer? - WebMD, 12/14/05 -
"Women who had the highest dietary
calcium intake were 20% less likely to have been diagnosed with breast
cancer than those whose diets were lowest in dietary calcium"
-
Iron, calcium linked to lung cancer - Nutra USA, 12/5/05 -
"The risk of lung cancer increased
by 50 per cent for calcium intake greater than 1270 mg per day ... the
increased lung cancer risk was the result of nonheme iron [iron from plant
sources]… heme iron [from animal sources] was associated with decreased risk
of lung cancer"
-
Too much calcium may raise prostate cancer risk - Nutra USA, 11/15/05 -
"men who consumed more than 2000mg
of calcium per day nearly doubled their risk of developing prostate cancer"
-
Women Need More Calcium, Say Experts - WebMD, 9/28/05
-
Postmenopausal Women Falling Far Short of Calcium Goals:
Presented at ASBMR
- Doctor's Guide, 9/28/05 - "A study finds that 85% of postmenopausal women do not
consume enough calcium every day, and on average consume about 500 mg less
than the US government's recommended daily intake (RDA)"
-
Calcium Supplements May Help Prevent Polyps - WebMD, 7/19/05 -
"people who took calcium had about a
25% lower risk of developing polyps in their colon"
-
Calcium, Vitamin D in Diet May Prevent PMS - WebMD, 6/13/05 -
"Those who ate about four servings a
day of low-fat dairy or yogurt or fortified orange juice had a 40% lower
risk of PMS than those who did not. That is about 1,200 milligrams of
calcium or 400 international units (IU) of vitamin D each day"
-
Fortified
Orange Juice May Not Deliver What You Expect - CBS 2 Chicago, 5/24/05 -
"calcium in some juices is absorbed
better than others ... a kind of calcium called calcium citrate malate is
the best absorbed. It's found in Tropicana juice"
-
Calcium Supplements Keep on Working Even After They Are Stopped -
Doctor's Guide, 4/21/05 - "People at
high risk of colon cancer appear to reduce the risk of developing polyps
while taking calcium supplements and continue to benefit for as long as 5
years after they stop taking them"
-
Statins Lower Prostate Cancer Risk - WebMD, 4/18/05 -
"long-term use of calcium
supplements protects against the development of potentially precancerous
colon polyps for years after you stop taking them"
-
Dairy calcium has 'no effect' on weight - Nutra USA, 4/18/05
-
Calcium as Part of a Normal Protein Diet May Increase Fecal Fat and Energy
Excretion - Medscape, 3/29/05 -
"A short-term increase in dietary calcium intake, together with a normal
protein intake, increased fecal fat and energy excretion by [approximately]
350 kJ/day ... This observation may contribute to explain why a high-calcium
diet produces weight loss, and it suggests that an interaction with dietary
protein level may be important"
-
Osteoporosis and Bone Health - Physician's Weekly, 3/21/05 -
"Calcium and vitamin D intakes are
far below recommended levels for all ages, sexes, and races in the United
States"
-
Study: Dairy Not Best Source of Calcium - WebMD, 3/7/05 -
"Of 37 studies reviewed, 27 were
found to show no relationship between dairy or dietary calcium and bone
health in children and young adults. The remaining studies found only a
small association"
-
Calcium Boost To Youths’ Bones Could Reduce Osteoporosis Risk
- Science Daily, 2/1/05 -
"elevated
calcium use by pre-adolescent girls is likely to help prevent fractures and
osteoporosis much later in life"
- Calcium May Help Prevent Colorectal Cancer -
WebMD, 1/28/05
- Calcium Supplements: Benefits and Risks -
Medscape, 1/26/05 -
"Perhaps the
most effective method of preventing osteoporosis is ingestion of adequate
calcium. Experts suggest the daily requirement for calcium is 1,300 mg for
people ages 9 to 18, 1,000 to 1,200 mg for adults 19 to 50, and 1,500 mg for
people over 50 ... You should take only the amount of calcium recommended.
Ingesting high doses of calcium each day can be harmful and can cause kidney
stones"
-
UT Southwestern Researchers Find Calcium Intake Contributing
Factor In Formation Of Kidney Stones - Science
Daily, 1/19/05 -
"Individuals
with either calcium oxalate or calcium phosphate kidney stones should not
take extra calcium on their own as suggested by previous research, but
should check with their doctors to determine the dietary guidelines that
work best for them"
-
Calcium Intake Contributing Factor In Formation Of Kidney
Stones - Doctor's Guide, 12/29/04 -
"urinary
calcium - the amount of calcium in a person's urine - is an important
contributing factor in the formation of both types of kidney stones. Earlier
studies had downplayed the significance of calcium when compared to the
levels of oxalate in urine, and even encouraged kidney stone patients to
increase their dietary intake of calcium"
-
The high five for hypertension -
Functional Foods & Nutraceuticals, 12/04 -
"Co-enzyme
Q10 ...
Omega-3 fatty acids ...
Garlic ... L-arginine
... Calcium"
- Calcium's
role in cancer - MSNBC, 12/10/04
-
Scientists call for calcium, vitamin D fortification
- Nutra USA, 7/28/04 -
"Americans consume inadequate
dietary calcium and vitamin D – far below the recommended levels established
by the Food Nutrition Board, Institute of Medicine of the National Academy
of Sciences" - See
iHerb
or
Vitacost
vitamin D products.
-
Calcium More Protective Against Some Polyps
- WebMD, 6/15/04 -
"The calcium group had 18% fewer noncancerous
polyps and 35% fewer advanced polyps ... compared with the placebo group ...
her study suggests that total calcium intake over 1,200 mg daily is
necessary for colon protection -- and that a high-fiber diet with modest
levels of fat will boost the protective effects"
-
Milk: It Does a Health Care System Good
- WebMD, 1/29/04 -
"estimated the
health benefits and health care cost savings involved if all Americans
increased their daily intake of calcium to the recommended level. For most
adults, the recommended intake ranges from 1,000-1,500 mg per day ...
Fractures due to osteoporosis would be reduced by 20% in a year ... High
blood pressure would be reduced by 40% in one year"
-
The Changing Paradigm in Osteoporosis Treatment
- Physician's Weekly, 1/5/04 -
"Patients
should wait 4 to 6 hours between doses of calcium servings because the body
will not absorb more than 500 mg at a time"
-
Calcium And Vitamin D Collaborate To Reduce Colorectal Cancer
Risk - Intelihealth, 12/3/03
- Calcium Intake Plus Vitamin D May Protect Against Colon Adenomas
- Medscape, 12/2/03 -
"Calcium
supplementation reduces the rate of
colon adenomas, but only if
vitamin D levels are adequate"
-
Elevated Serum Calcium Linked to Increased Carotid-Artery
Plaque Thickness - Doctor's Guide, 11/4/03 -
"People with
elevations of serum calcium also have thicker carotid-artery plaques, and
therefore may be at greater risk of a stroke ... This finding is important,
because the risk of myocardial infarction…increases 5-fold within 5 years
for every 0.16 mm of carotid-wall thickness"
-
Increasing Calcium More Likely to Lower Blood Pressure Than
Decreasing Sodium - Doctor's Guide, 10/12/03 -
"When the diet is "balanced with no
deficit in minerals, salt is not a problem," he said. "Salt becomes a
problem when the diet is calcium deficient. Specifically, as calcium intake
increases, blood pressure decreases."" - See
Tums
at drugstore.com.
-
Best Ways To Fight Osteoporosis -
CBS News, 9/18/03 -
"64 percent of women don't know how
much calcium they need every day ... women from 19- to 50-years-old should
consume 1,000 mg; and women over 50-years-old should consume 1,200 mg ... a
high calcium intake will not protect a person against
bone loss caused by estrogen deficiency,
physical inactivity, smoking, alcohol abuse or various medical disorders or
treatments"
- Supplement
Week: Calcium: How much is too much? - Dr. Weil, 9/4/03
-
Low Dietary Calcium May be Major Cause of Nutritional Rickets
Among North American Infants - Doctor's Guide,
8/12/03 -
"New
research shows that some North American infants are not receiving enough
dietary calcium and, as a result, are developing rickets -- a disease
usually attributed to a lack of
vitamin D or insufficient exposure to sunlight
-- at a higher level than previously thought"
-
Vitamin D and Calcium Supplementation Effective for
Prevention and Treatment of Osteoporosis -
Doctor's Guide, 7/18/03 -
"Adequate
vitamin D and calcium intake is essential to
the prevention and treatment of
osteoporosis. The Institute of Medicine
(IOM) recommends 200 IU/day of vitamin D for women aged 50 or younger years,
400 IU/day for those aged 51-70 years, and 600 IU/day for those older than
70 years ... In women over the age of 65, there is increased risk of
osteoporotic fracture of the hip and non-vertebral sites. Daily vitamin D
intake between 800 and 900 IU and 1200-1300 mg of calcium for this
population results in increased bone density, decreased bone turnover, and
decreased non-vertebral fractures ... Studies have linked vitamin D
supplementation to a decrease in body sway, suggesting that vitamin D
supplementation may protect against fracture by preventing falls" -
See
drugstore.com/GNC calcium plus vitamin D supplements
.
-
High Dietary Calcium Intake Associated with Lower Age-Related
Hypertension - Doctor's Guide, 7/16/03 -
"In industrialized nations,
SBP
increases with age, whereas diastolic
blood pressure (DBP)
tends to decrease with age, thereby increasing
pulse pressure (defined as the difference between
SBP
and
DBP)
... higher calcium intake was associated with lower rates of age-related
increases of systolic blood pressure and pulse pressure ... If the calcium
intake of the general population were to increase to above 1,200 mg, the
incidence of isolated systolic hypertension in the elderly might be
decreased"
- See
drugstore.com/GNC calcium supplements
.
- Guarding
Your Gums? - Dr. Weil, 6/16/03 -
"Periodontal
disease is a chronic gum infection caused by bacteria in plaque ...
Coenzyme Q10: Take 120 mg per day of a soft-gel
form with meals ... young women who get less than 800 mg of calcium a day
have double the risk of periodontal disease" - See
iHerb
or
Vitacost
coenzyme Q10 products.
-
Regulators want to stop false health claims about coral
calcium supplements - USA Today, 6/10/03 -
"The Federal
Trade Commission is asking a federal court in Chicago to shut down an
operation that sells Coral Calcium Supreme, a product advertised with one of
the most widely run infomercials on cable television this year"
-
The Dairy Calcium in Yogurt Helps People Lose Belly
- WebMD, 4/15/03 -
"put 34 obese
people on a low-cal diet. Sixteen of them got pills with 400 to 500 mg of
calcium per day. The other 18 people ate enough yogurt to give them 1100 mg
of calcium per day ... After 12 weeks, everybody lost a lot of fat ... Sixty
percent of the yogurt eaters'
weight loss was
belly fat, while only 26% of the comparison
group's loss was belly fat"
-
Calcium for Weight Loss? - WebMD,
4/14/03
-
Calcium Supplementation and Exercise Improves Bone Mineral
Status in Adolescent Girls - Doctor's Guide,
4/10/03
-
Vitamin D Plus Calcium Supplements Boosts Calcium Absorption
- WebMD, 4/1/03 -
"We need
calcium for
good bones, but
vitamin D is equally important -- it helps the
body with calcium absorption. In fact, calcium supplements plus vitamin D
can increase calcium absorption by up to 65%"
-
Postmenopausal Women May Need Supplements To Suppress
Parathyroid Hormone Levels - Doctor's Guide,
12/20/02 -
"These
findings may call for widespread supplementation with calcium and
vitamin D may be required in postmenopausal
women"
-
Formulation of some calcium supplements interferes with
calcium absorption - Doctor's Guide, 9/23/02 -
"The formulation of some calcium
carbonate supplements significantly interferes with calcium absorption and
patients may thus be getting substantially less calcium than might be
presumed based on product labeling ... the team found that only two calcium
carbonate supplements - both oral tablets, although one was chewable - had
rates of absorbability that were comparable to plain calcium carbonate ...
The other six supplements were substantially less absorbable ... Our
findings suggest that pharmaceutical formulation affects absorbability...and
we encourage industry to study this issue and to produce calcium supplements
with demonstrated absorbability"
-
Osteoporosis in Elderly Men Underestimated
- Doctor's Guide, 6/24/02 -
"As many as 30 percent of men over
65 years old may have
osteoporosis ... The serum
thyroid-stimulating hormone (TSH), although normal, was slightly lower in
men with osteoporosis, an average of 1.57±0.74 in comparison to an average
of 2.34±1.93 in men with no osteoporosis ... Because both groups of men have
low-normal 25-OH
vitamin D, and low urinary calcium, the
investigators suggest that patients in their situation, could benefit from
enhancing their nutritional status"
- Counting on
Coral Calcium? - Dr. Weil, 6/18/02
-
Getting Calcium On Young Girls' Radar
- Intelihealth, 5/23/02 -
"Ninety percent of girls ages 9 to
12 don't get enough calcium in their diets ... Ninety to 98 percent of your
skeletal system is developed by age 20, so it's important that these
bone-healthy activities are done early. After that, you're either going to
maintain the
bone density or you're going to lose it"
-
Calcium and Vitamin D3 Effective and Cost-Saving in
Preventing Hip Fracture in Elderly European Women
- Doctor's Guide, 5/13/02 -
"simple dietary supplementation with
calcium and vitamin D not only helps prevent
hip fracture in institutionalized elderly
women, it also saves up to 711,000 Euros (some US $640,000) per 1000 treated
... One group received elemental 1200 mg/day calcium plus 800 IU/day vitamin
D3, while the other received a placebo. After three years, 25 percent fewer
hip fractures were found among members of the supplemented group ... The
savings may even be greater than this: remember, this study only takes into
account hip fractures, but supplementation could prevent many other types of
fracture as well"
-
Calcium, Vitamin D3 Supplementation Reduces
Hyperparathyroidism And Hip Fracture - Doctor's
Guide, 5/9/02 -
"Supplementation with a combination of
calcium and vitamin D3 reverses
hyperparathyroidism and the risk of hip fracture in elderly women"
-
Calcium Citrate May Also Lower Cholesterol In Women
- Doctor's Guide, 4/24/02 -
""This study showed that 1 gram of
calcium (as the citrate) taken daily lowers the damaging component of blood
cholesterol (LDL or low-density lipoprotein), and increases the protective
cholesterol (HDL or high-density lipoprotein). As a result, calcium citrate
may reduce the incidence of heart attacks and angina in postmenopausal
women," ... study was designed to determine the effect of calcium
supplementation with calcium citrate (1 gram daily as
Citracal®
Ultradense™
calcium citrate) on circulating lipid concentrations in normal older women"
-
Aging Bone Mineral Density Better With High Protein Diet Plus
Extra Calcium, Vitamin D - Doctor's Guide, 4/1/02
-
High-Protein
Diet Could Repair Bone Loss - WebMD, 3/25/02 -
"The supplement group --
particularly those who ate a diet high in
protein -- had significantly better bone mass
density -- an accurate measure of bone loss.
Those who took the placebo, however, had less calcium absorbed into their
bloodstream when they consumed more protein"
-
Bones Need Both
Calcium and Phosphorus - WebMD, 3/20/02 -
"taking
a lot of calcium supplements without enough phosphorus could be a waste of
money ... Rhodia, a major producer of calcium phosphates, partially funded
this research" - I read an article on this several years ago and it
said that the average American diet already gets too much phosphorus. - Ben
-
Calcium Intake May Be Associated With Reduced Risk Of Colon
Cancer - Intelihealth, 3/19/02 -
"Men and women
who included more than 700 to 800 mg of calcium in their diets each day had
a 40% to 50% lower risk of distal colon cancer compared with participants
taking less than 500 mg of calcium each day"
-
Boning Up on
Calcium Fights Colon Cancer - WebMD, 3/19/02
-
Study: Calcium may help determine risk of stroke
- USA Today, 1/31/02
-
Kids Plagued by
'Calcium Crisis' - WebMD, 12/14/01 -
"Only 14% of girls and 36% of boys
age 12 to 19 in the U.S. are getting the recommended amounts of calcium,
according to the U.S. Department of Agriculture ... Close to 90% of adult
bone is established by the end of the teen years. So if kids are off to a
bad start in getting enough calcium, says the National Institute of Child
Health and Human Development (NICHD),
down the road, they are at serious risk of developing the brittle-bone
disease osteoporosis as well as other bone diseases"
-
"Calcium Crisis" Affects American Youth
- NIH, 12/10/01
-
A Better Bone Builder [calcium threonate]
- Nutrition Science News, 12/01
-
Calcium, Vitamin
D Help You Hold on to Those Pearly Whites - WebMD, 10/29/01 -
"examined 145 healthy men and women
aged 65 and older who had taken either calcium plus
vitamin D supplements or placebo ... The
calcium was given at a dose of 500 mg and vitamin D at 700 IU
daily ... 27% of the placebo group, but only 13% of the supplement group,
lost one or more teeth during the three-year study ... Once the study was
finished, the researchers continued to count teeth for a couple of more
years. Again, they found that those taking in at least 1,000 mg of calcium
each day were able to hold on to more teeth"
-
Mining Mineral Supplements -
Nutrition Science News, 7/01 -
"One approach is to provide both
minerals, but at different times of day in different products. Another is to
accept the antagonism but provide enough of each mineral so each can be of
benefit. If it is eventually shown that certain mineral complexes are only
mildly antagonistic, then providing these forms together would enhance
patient compliance"
- Calcium
Supplementation Prevents Bone Loss in Renal Transplant Patients -
Doctor's Guide, 5/13/01
-
Calcium Pills
May Stave Off Colon Cancer - WebMD, 3/9/01 -
"among patients who took calcium
(for one year), the size and growth of the benign tumors -- as measured by
pathologists who looked at tissue biopsies -- was reduced by 58%. In
contrast, only a 26% reduction was seen in patients who did not take calcium
. . . The protective effect of calcium was most pronounced among the
patients on a low-fat diet and taking calcium: 73% of those patients had
noticeable reductions in adenomas. In contrast, there were no differences in
adenoma reductions between high-fat eaters in the calcium and no-calcium
groups"
-
Calcium supplements do not help nails - CNN, 12/14/00
-
Calcium Citrate Shown to Have Superior Bioavailability and Protects Against
Bone Loss - Medscape, 11/21/00 -
"the calcium supplement formulation calcium citrate was 2.5 times more
bioavailable than calcium carbonate, even when given with a meal, the
optimum method of ensuring calcium carbonate absorption" - See
Citracal
at drugstore.com.
-
Low Calcium May
Equal High Lead Levels in Pregnant Women - WebMD, 11/8/00
- Calcium
Deficiency Permits Faster Lead Release From Pregnant Women's Bones -
Doctor's Guide, 11/6/00
-
Bone Up on Osteoporosis - Nutrition Science News, 11/00
-
Calcium Less Available from Soy Milk - Nutrition Science News, 10/00
-
Kids Taking
Steroids for Asthma Need Calcium and Exercise - WebMD, 10/20/00
-
Keep That Smile!
Calcium and Vitamin D Prevent Tooth Loss - WebMD, 9/27/00
-
Lead still in calcium supplements - CNN, 9/20/00
-
Bone Up on
Calcium Supplements, What Are Their Benefits and Risks? - WebMD, 9/19/00
-
Study Turns Up
Lead in Some Calcium Supplements - WebMD, 9/19/00
-
Calcium Supplements Have Lead - Intelihealth, 9/20/00
-
Individuals Vary Greatly In Their Ability To Absorb Calcium - Doctor's
Guide, 8/1/00
- Vitamin D
Plus Calcium Prevents Falls in Elderly Women - Doctor's Guide, 6/17/00
- Majority
Of Women Treated For Osteoporosis Not Taking Calcium Supplements -
Doctor's Guide, 6/15/00
-
Hearts & Bones: Calcium's Many Applications - Nutrition Science News,
2/00
-
Postmenopausal Bone Loss Prevented With Low Dose HRT Plus Calcium -
Doctor's Guide, 6/2/99
-
Essential Nutrients for Endurance Athletes - Nutrition Science News,
5/99
-
Calcium, Keep What You Take - Life Extension Magazine, 3/99
-
Anti-dairy group opens campaign attacking benefits of milk - CNN, 3/1/99
- Calcium
Supplements Help Prevent Polyp Recurrence - Doctor's Guide, 1/14/99
-
Weight
training, calcium, hormones the key to fighting osteoporosis - CNN,
11/6/98
-
Guidelines to prevent, diagnose and treat osteoporosis expected - CNN,
11/5/98
-
Study
says calcium may cut colon cancer risk - CNN, 9/22/98
- Low
Dietary Calcium, Low Vitamin C Linked To Increased Risk Of Gum Disease -
Doctor's Guide, 6/29/98
- Extra
Calcium Benefits Women On Hormone Replacement Therapy
- Doctor's Guide, 1/15/98 -
"women who consumed high levels of
calcium in conjunction with hormone replacement therapy (HRT) had much
greater increases in bone mass than those who used either estrogen or
calcitonin alone"
-
Misconceptions Keep Some Wormen for Taking Action on Osteroporosis -
Doctor's Guide, 10/9/97
- Female
Teens Need Calcium During Window Of Opportunity - Doctor's Guide, 9/5/97
- Calcium,
Vitamin D Combo Reduces Bone Loss, Fracture Rate for Older People -
Doctor's Guide, 9/4/97
-
Report:
Americans need more calcium - CNN, 8/13/97
- Calcium
Intake During Pregnancy May Predict Life Long Cardiovascular Risk -
Doctor's Guide, 10/10/96
Abstracts:
-
Vitamin or
mineral supplement intake and the risk of head and neck cancer: Pooled analysis
in the INHANCE consortium - Int J Cancer. 2011 Dec 15 -
"To investigate the potential role of vitamin or mineral
supplementation on the risk of head and neck cancer (HNC), we analyzed
individual-level pooled data from 12 case-control studies ... A decreased risk
of HNC was observed with ever use of vitamin C (OR=0.76, 95% CI=0.59-0.96) and
with ever use of calcium supplement (OR=0.64, 95% CI=0.42-0.97). The inverse
association with HNC risk was also observed for 10 or more years of vitamin C
use (OR=0.72, 95% CI=0.54-0.97) and more than 365 tablets of cumulative calcium
intake (OR=0.36, 95% CI=0.16-0.83), but linear trends were not observed for the
frequency or duration of any supplement intake. We did not observe any strong
associations between vitamin or mineral supplement intake and the risk of head
and neck cancer"
-
Serum
Calcium Levels and Hypertension Among US Adults - J Clin Hypertens
(Greenwich). 2011 Oct;13(10):716-21 - "Elevated serum
total calcium levels were positively associated with hypertension, independent
of potential confounders including C-reactive protein, estimated glomerular
filtration rate, serum albumin, 25(OH)D, and phosphorous. Compared with the
lowest quartile of serum total calcium (referent category), the multivariable
odds ratio (95% confidence interval) of hypertension was 1.49 (1.15-1.93) for
the highest quartile (P=.005). This association persisted in subgroup analyses
stratified by sex, age, and race-ethnicity. In contrast, serum ionized calcium
levels were not associated with hypertension. Higher serum total calcium levels
are positively associated with hypertension in a representative sample of US
adults"
-
Calcium
intake and prostate cancer among African Americans: Effect modification by
vitamin D receptor calcium absorption genotype - J Bone Miner Res. 2011 Sep
1 - "Compared to men in the lowest quartile of calcium
intake, men in the highest quartile had an approximately two-fold increased risk
of localized and advanced prostate cancer (odds ratio [OR]= 2.20, 95% confidence
interval [CI]= 1.40, 3.46), with a significant dose-response. Poor absorbers of
calcium (VDR Cdx2 GG genotype) had a significantly lower risk of advanced
prostate cancer (OR= 0.41, 95% CI = 0.19, 0.90). The gene-calcium interaction
was statistically significant (p = 0.03). Among men with calcium intake below
the median (680 mg/day), carriers of the G allele had an approximately 50%
decreased risk compared to men with the AA genotype. These findings suggest a
link between prostate cancer risk and high intestinal absorption of calcium"
-
Serum
Calcium Level is Associated with Metabolic Syndrome in the General Population.
FIN-D2D-study - Eur J Endocrinol. 2011 Jun 9 - "The
mean age in men was 60.3±8.3 years and in women 59.8±8.5 years. The prevalence
of MetS was 50.7 % in women and 55.8 % in men. The prevalence of MetS and its
components, except HDL-cholesterol, increased in a linear trend with increasing
serum calcium (p<0.001), even after adjustment for age, physical activity,
alcohol, vitamin D intake, calcium intake and smoking. The threshold value for
serum calcium for MetS was 2.50 mmol/L in this population. The association of
MetS with total serum calcium was similar even after exlusion of patients
treated with hypertensive drugs. The drug treatments for hypertension,
dyslipidaemia and diabetes increased in a similar pattern. Conclusions: Serum
calcium level is associated with MetS and its components, except
HDL-cholesterol"
-
Effect of a
high-calcium energy-reduced diet on abdominal obesity and cardiometabolic risk
factors in obese Brazilian subjects - Int J Clin Pract. 2010
Jul;64(8):1076-83 - "(i) a low-calcium diet (LCD; < 500
mg/day) or (ii) a HCD [1200-1300 mg/day ... 16 weeks of energy restriction, a
significant reduction was observed in all anthropometric parameters, metabolic
variables (except for high-density lipoprotein cholesterol) and blood pressure
levels in both the groups. Insulin was significantly reduced only in the HCD
group. Subjects on the HCD compared with those on the LCD exhibited a greater
reduction in waist circumference (p = 0.002), waist-to-hip ratio (p = 0.0001),
diastolic blood pressure (p = 0.04) and mean blood pressure (p = 0.03).
Conclusions: Our study suggests that increased calcium intake may enhance the
beneficial effects of energy restriction on abdominal obesity and blood
pressure"
-
Independent
and joint effects of serum 25-hydroxyvitamin D and calcium on ovarian cancer
risk: A prospective nested case-control study - Eur J Cancer. 2010 Jun 18 -
"We observed a significant inverse association between
calcium and ovarian cancer risk. Relative risk (estimated as odds ratio, OR)
comparing the highest quartile to the lowest quartile was significantly
decreased; 0.41 [95% confidence interval (CI) 0.19-0.85, P-trend 0.004]. Even
though a comparable association between 25-OHD and ovarian cancer did not reach
statistical significance (OR 0.57, 95% CI 0.26-1.24, P-trend 0.07), having
sufficient (>75nmol/L) serum 25-OHD levels compared to insufficient serum 25-OHD
was associated with a significantly decreased risk of ovarian cancer (OR 0.32;
95% CI 0.12-0.91, p-value 0.03)"
-
Dietary
Calcium and Magnesium Intake and Mortality: A Prospective Study of Men - Am
J Epidemiol. 2010 Feb 19 - "Dietary calcium was
associated with a statistically significant lower rate of all-cause mortality
(hazard ratio (HR) = 0.75, 95% confidence interval (CI): 0.63, 0.88; P(trend) <
0.001) and a nonsignificantly lower rate of CVD (HR = 0.77, 95% CI: 0.58, 1.01;
P(trend) = 0.064) but not cancer mortality (HR = 0.87, 95% CI: 0.65, 1.17;
P(trend) = 0.362) when the highest intake tertile (mean = 1,953 mg/day; standard
deviation (SD), 334) was compared with the lowest (990 mg/day; SD, 187)"
-
Vitamin
D, Calcium Shown to Reduce Mortality - Medscape, 9/17/09 -
"Vitamin D and calcium have been shown to help lower
mortality risk among older people, but the benefits are not necessarily
explained by a reduced risk for hip fracture ... When given with vitamin D,
calcium reduced mortality (hazard ratio [HR], 0.88 [0.81–0.97]; P < .01),
whereas studies involving vitamin D alone showed no significant reduction in
mortality" - See
vitamin D products at iHerb
.
-
Serum
calcium and the risk of prostate cancer - Cancer Causes Control. 2009 Apr 18
- "These data do not support the hypothesis that high
serum calcium levels is a risk factor for prostate cancer. On the contrary, the
data suggest that high serum levels of calcium in young overweight men may be a
marker for a decreased risk of developing prostate cancer"
-
Vitamin D, calcium combo may cut exercise-related stress fractures - Nutra
USA, 4/25/08 - "randomly assigned the recruits to
receive daily supplements of 2,000 mg of calcium and 800 IU of vitamin D, and
the other group received a placebo ... Women receiving the vitamin-mineral
combination were 20 per cent less likely to experience the fractures" - [Abstract]
-
Calcium
and vitamin d supplementation decreases incidence of stress fractures in female
navy recruits - J Bone Miner Res. 2008 May;23(5):741-9 -
"randomized them to 2000 mg calcium and 800 IU vitamin
D/d or placebo ... found a 21% lower incidence of fractures in the supplemented
versus the control group" - [Nutra
USA]
-
Dietary intake adequacy and cognitive function in free-living active elderly: A
cross-sectional and short-term prospective study - Clin Nutr. 2007 Dec 12 -
"mini-mental state examination (MMSE) ... subjects whose
consumption of calcium was above the dietary reference intake had a
significantly higher odds ratio (OR) of improving their MMSE (OR=5.41; 95% CI:
1.44-20.29)"
-
The influence of calcium consumption on weight and fat following 9 months of
exercise in men and women - J Am Coll Nutr. 2007 Aug;26(4):350-5 -
"Average calcium consumption was 987 +/- 389 mg/day for
men and 786 +/- 276 mg/day for women. Weight change over the 9 months was -4.6
+/- 4.6 kg for men and 0.2 +/- 3.3 kg for women ... Weight and fat weight loss
as a result of nine months of moderate intensity exercise may be improved by
increased calcium consumption in men but was not observed in women" -
Note: 4.6 kg is 10.14 lbs.
-
Increased calcium intake does not completely counteract the effects of increased
phosphorus intake on bone: an acute dose-response study in healthy females -
Br J Nutr. 2007 Oct 1;:1-8 - "When P intake was above
current recommendations, increased Ca intake was beneficial for bone, as
indicated by decreased S-PTH concentration and bone resorption. However, not
even a high Ca intake could affect bone formation when P intake was excessive"
-
Bone mineral density and bone markers in patients with a recent low-energy
fracture: effect of 1 y of treatment with calcium and vitamin D - Am J Clin
Nutr. 2007 Jul;86(1):251-9 - "A 1-y intervention with
calcium and vitamin D reduced bone turnover, significantly increased BMD in
patients younger than 70 y, and decreased bone loss in older patients. The
effect of treatment was related to physical performance"
-
Vitamin D and calcium supplementation reduces cancer risk: results of a
randomized trial - Am J Clin Nutr. 2007 Jun;85(6):1586-91 -
"Improving calcium and vitamin D
nutritional status substantially reduces all-cancer risk in postmenopausal
women"
-
Calcium plus vitamin d supplementation and the risk of postmenopausal weight
gain - Arch Intern Med. 2007 May 14;167(9):893-902 -
"Calcium plus cholecalciferol
supplementation has a small effect on the prevention of weight gain, which was
observed primarily in women who reported inadequate calcium intakes"
-
Two-year randomized controlled trial of vitamin K1 (phylloquinone) and vitamin
D3 plus calcium on the bone health of older women - J Bone Miner Res. 2007
Apr;22(4):509-19 - "women who took
combined vitamin K and vitamin D plus calcium showed a significant and sustained
increase in both BMD and BMC at the site of the ultradistal radius"
-
The Effects of Calcium and Vitamin D Supplementation on Blood Glucose and
Markers of Inflammation in Non-diabetic Adults - Diabetes Care. 2007 Feb 2 -
"Among participants with IFG at baseline
those who took combined calcium-vitamin D supplements had a lower rise in FPG at
3 years compared to those on placebo"
-
Prolonged effect of calcium supplementation on risk of colorectal adenomas in a
randomized trial - J Natl Cancer Inst. 2007 Jan 17;99(2):129-36 -
"placebo or 1200 mg of elemental calcium
daily for 4 years ... During the first 5 years after randomized treatment ended,
subjects in the calcium group still had a substantially and statistically
significantly lower risk of any adenoma than those in the placebo group (31.5%
versus 43.2%"
-
Vitamin D and calcium intake in relation to type 2 diabetes in
women - Diabetes Care. 2006 Mar;29(3):650-6 -
"A combined daily intake of >1,200 mg
calcium and >800 IU vitamin D was associated with a 33% lower risk of type 2
diabetes with RR of 0.67 (0.49-0.90) compared with an intake of <600 mg and 400
IU calcium and vitamin D, respectively"
-
Effect of cholecalciferol plus calcium on falling in ambulatory older men
and women: a 3-year randomized controlled trial - Arch Intern Med. 2006
Feb 27;166(4):424-30 - "Long-term
dietary cholecalciferol-calcium supplementation reduces the odds of falling
in ambulatory older women by 46%, and especially in less active women by
65%"
-
Calcium plus vitamin D supplementation and the risk of fractures - N
Engl J Med. 2006 Feb 16;354(7):669-83
-
Calcium plus vitamin D supplementation and the risk of colorectal cancer
- N Engl J Med. 2006 Feb 16;354(7):684-96
-
Vitamin D and calcium deficits predispose for multiple
chronic diseases - Eur J Clin Invest. 2005
May;35(5):290-304 - "calcium and vitamin D deficits increase the risk of
malignancies, particularly of colon, breast and prostate gland, of chronic
inflammatory and autoimmune diseases (e.g. insulin-dependent diabetes
mellitus, inflammatory bowel disease, multiple sclerosis), as well as of
metabolic disorders (metabolic syndrome, hypertension)"
-
Overweight Postmenopausal Women Lose Bone With Moderate
Weight Reduction and 1 g/day Calcium Intake - J
Bone Miner Res. 2005 Mar;20(3):455-63 -
"Despite an intake of
1 g Ca/day, bone loss occurred at some sites because of weight loss. Calcium
intake of 1.7 g/day will minimize bone loss during weight loss in
postmenopausal overweight women"
-
Effects of calcium supplementation on circulating lipids :
potential pharmacoeconomic implications - Drugs
Aging. 2004; 21(1): 7-17 -
"calcium and lipids
bind to one another in the gut, each interfering with the other's
absorption. Calcium also causes malabsorption of bile acids, which is likely
to contribute further to malabsorption of fat ... The largest randomised
controlled trial of calcium effects on lipids was carried out in 223 healthy
postmenopausal women, and found that low density lipoprotein-cholesterol
(LDL-C) decreased 6.3% and high density lipoprotein-cholesterol (HDL-C)
increased by 7.3% at 1-year. The resultant 16.4% increase in HDL-C/LDL-C
ratio would be predicted to reduce cardiovascular event rates by 20-30%,
which is consistent with the available observational data"
-
Dietary calcium lowers the age-related rise in blood pressure
in the United States: the NHANES III survey - J
Clin Hypertens (Greenwich). 2003 Mar-Apr;5(2):122-6 -
"higher calcium intake was associated with lower rates of
age-related increases of systolic blood pressure and
pulse pressure (p<0.001). If the calcium intake of the general
population were to increase to above 1200 mg, the incidence of isolated
systolic hypertension in the elderly might be decreased"
-
Calcium intake, body composition, and lipoprotein-lipid
concentrations in adults - Am J Clin Nutr. 2003
Jun;77(6):1448-52 -
"divided into 3 groups
on the basis of their daily calcium intake: groups A (< 600 mg), B (600-1000
mg), and C (> 1000 mg) ... In women, a significantly greater ratio of total
to HDL cholesterol (P < 0.05) was observed in group A than in group C after
correction for body fat mass and waist circumference. In women, body weight,
percentage body fat, fat mass, body mass index, waist circumference, and
total abdominal adipose tissue area measured by computed tomography were
significantly greater (P < 0.05) in group A than in groups B and C, even
after adjustments for confounding variables. Comparable trends were observed
in men, but not after adjustment for the same covariates. CONCLUSION: A low
daily calcium intake is associated with greater adiposity, particularly in
women. In both sexes, a high calcium intake is associated with a plasma
lipoprotein-lipid profile predictive of a lower risk of coronary heart
disease risk compared with a low calcium intake"
-
Calcium, vitamin D, milk consumption, and hip fractures: a
prospective study among postmenopausal women - Am.
J. of Clin. Nutr., 2/03 -
"Women consuming 12.5
µg vitamin D/d from food plus supplements had
a 37% lower risk of hip fracture (RR =
0.63; 95% CI: 0.42, 0.94) than did women consuming < 3.5 µg/d. Total calcium
intake was not associated with hip fracture risk (RR = 0.96; 95% CI: 0.68,
1.34 for 1200 compared with < 600 mg/d). Milk
consumption was also not associated with a lower risk of hip fracture (P for
trend = 0.21)"
-
Calcium, vitamin D, dairy products, and risk of colorectal
cancer in the cancer prevention study II nutrition cohort
- Cancer Causes Control 2003 Feb;14(1):1-12 - "Total calcium intake (from diet and supplements) was
associated with marginally lower colorectal cancer
risk in men and women ... The association was strongest for calcium from
supplements ... Total vitamin D intake (from diet and multivitamins) was
also inversely associated with risk of colorectal cancer, particularly among
men"
-
Calcium supplementation prevents seasonal bone loss and
changes in biochemical markers of bone turnover in elderly New England
women: a randomized placebo-controlled trial
- J Clin Endocrinol Metab. 1998 Nov;83(11):3817-25
-
Dietary protein intake and urinary excretion of calcium: a
cross-sectional study in a healthy Japanese population
- Am J Clin Nutr. 1998 Mar;67(3):438-44 - "Our findings suggest
that excess protein, especially that rich in sulfur-containing amino acids,
in habitual diets may augment calcium excretion in the urine, at least in
the elderly."
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