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Home > Health Conditions > ApoB.
ApoB (apolipoprotein B)
Alternative News:
-
Omega-3
fatty acid containing diets decrease plasma triglyceride concentrations in mice
by reducing endogenous triglyceride synthesis and enhancing the blood clearance
of triglyceride-rich particles - Clin Nutr. 2008 Mar 22 -
"Levels of hepatic TG and apoB synthesis were 30-50% and
42% lower in mice fed with the fish oil diet compared to the other three diets.
In addition, compared to soy oil diet, fish oil feeding significantly increased
blood clearance of chylomicron-like lipid emulsions by 21-26%" - See
Mega Twin EPA at
iHerb
 .
-
Resveratrol attenuates the expression of HMG-CoA reductase mRNA in hamsters
- Biochem Biophys Res Commun. 2007 Dec 28 - "The
concentrations of serum total cholesterol and triglyceride were significantly
lower in the resveratrol-fed group than in the control group. The resveratrol
contained diet significantly decreased Apo B, Lp(a), and
cholesterol-ester-transport protein (CETP) concentrations, but increased Apo A-I
levels and the Apo A-I/Apo B ratio. The contents of cholesterol and triglyceride
in hepatic tissue were significantly lower in the resveratrol group than in the
control group. Real-time PCR analysis revealed that HMGR mRNA expression was
significantly lower in the resveratrol group than in the control group" -
See
Jarrow Resveratrol 100 at iHerb.
-
Broccoli compound identified for heart benefits - Nutra USA, 10/3/07 -
"the indole-based compound, indole-3-carbinol, was
able to reduce the secretion of apolipoprotein B-100 (apoB) by 56 per cent,
and thereby confer cardiovascular benefits" - See
I3C products at iHerb.
-
Novel
Dietary Supplement [Sytrinol™] Shows Dramatic Effects in Lowering Cholesterol, LDL, and Triglycerides - Life Extension Magazine, 11/04 -
"those with the highest ratios of apolipoprotein B to apolipoprotein A were at the greatest risk of dying from a
heart attack ... treatment with Sytrinol™ substantially cut levels of plasma
total cholesterol (-20%), LDL (-22%), apolipoprotein B (-21%), and
triglycerides (-28%). Additionally, subjects in the second trial benefited
from a significant 5% increase in apolipoprotein A1, an important structural
protein of HDL" - See
Sytrinol products at iHerb
 .
- Fish Oil May Augment Atorvastatin As Treatment For Dyslipidemia In Obese, Insulin-Resistant Men - Doctor's Guide, 8/7/02 -
"fish
oils significantly decreased plasma levels of triglycerides and very low density lipoprotein-apoB, decreased the very low density lipoprotein-apoB secretion rate" - See TwinLab TwinEPA at
iHerb
 and
Vitacost .
- Randomized controlled trial of the effect of n–3 fatty acid supplementation on the metabolism of apolipoprotein B-100 and chylomicron remnants in men with visceral obesity1 - Am. J.
of Clin. Nutr., 2/03 - "Fish oil supplementation significantly (P < 0.05) lowered plasma concentrations of triacylglycerols (-18%) and VLDL apo B (-20%) and the hepatic secretion of VLDL apo B (-29%) compared with placebo" - Doing the math, 45% of 4 grams equals 1,800
mg of EPA, 39% of 4 grams equals 1,560 mg of DHA.
Other News:
-
Cholesterol Testing Not Enough for Some - WebMD, 3/27/08 -
"once LDL cholesterol is lowered to recommended levels
in high-risk patients, testing for the protein ApoB may more accurately identify
those still at risk for cardiovascular events"
-
HDL cholesterol and
large HDL particles not cardioprotective when adjusted for apoA-1 and apoB -
theheart.org, 2/4/08
-
Improving The Assessment Of Coronary Heart Disease Risk In Chinese - Science
Daily, 10/12/07 - "the risk of developing coronary heart
disease was more than three times as high in participants with the highest
values of both apolipoprotein B and the ratio of the total cholesterol over
HDL-C than patients who did not have the disease"
-
ApoB/apoA-I ratio: an independent predictor of insulin resistance in US
non-diabetic subjects - Eur Heart J. 2007 Sep 1 -
"In the US population, apoB/apoAI ratio is significantly associated with insulin
resistance in non-diabetic subjects"
- The
apo B/A-I Ratio -- A Stronger Predictor of Cardiovascular Events Than LDL,
HDL, or Total Cholesterol, Triglycerides, or Lipid Ratios - Medscape,
7/28/06 - "the predictive power of
the apo B/A-I ratio is superior to, and cannot be improved by adding, any
other lipid parameter or ratio"
-
Rosuvastatin Provides Better Rates of Lipid Lowering Compared to Other Statins - Doctor's Guide, 10/27/04 -
"switching to
rosuvastatin from another statin agent helped more patients achieve primary treatment goals for low-density lipoprotein cholesterol (LDL-C) and secondary apolipoprotein (apo)
B treatment goals in coronary heart disease (CHD) patients with high lipid levels"
- Scientists Tout New Cholesterol Test - Intelihealth, 9/1/04 -
"Globally, 50 percent of the risk of a heart attack is predicted by the apo B/apo A1 ratio"
- Non-HDL Cholesterol and Apolipoprotein B Predict Cardiovascular Disease Events Among Men With Type 2 Diabetes - Diabetes Care. 2004 Aug;27(8):1991-7 -
"Non-HDL cholesterol and apoB are more potent predictors of CVD incidence among diabetic men than LDL cholesterol. Statistically, the ratio of total to HDL cholesterol is the best predictor of CVD in this cohort of diabetic men"
- Bad Cholesterol, Worst Cholesterol - WebMD, 10/28/03
- Rosuvastatin Improves Apolipoprotein Levels - Doctor's Guide, 10/1/03
- FDA Approves New Lescol Indication To Reduce Triglycerides And Apo B - Doctor's Guide, 3/9/99
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