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Home > Anti-aging Research > Antidepressants > escitalopram
Cipralex®/Lexapro (escitalopram)
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News & Research:
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Lexapro (escitalopram oxalate) - rxlist.com
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Bupropion XL vs.
Escitalopram in Generalized Anxiety Disorder - Medscape, 3/11/08 -
"Response rates were significantly greater for
bupropion XL (100%) than for escitalopram (62%)" - That surprised me
because all the studies I've read had escitalopram beating just about
everything for depression.
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Recent Trials in Generalised Anxiety Disorder Highlight Escitalopram,
Duloxetine, and Anticonvulsants - Doctor's Guide, 11/21/07
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Data Presented Indicates Escitalopram may be a Promising Future Treatment
Option in Obsessive Compulsive Disorder - Doctor's Guide, 9/19/06
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Escitalopram Helps Prevents Relapses of Obsessive-Compulsive Disorder -
Doctor's Guide, 9/18/06
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Escitalopram Helps Prevent Relapse of Obsessive-Compulsive Disorder Symptoms
- Doctor's Guide, 5/25/06
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Double-blind Data Show No Effect With Escitalopram in Compulsive Shopping
Disorder - Doctor's Guide, 5/23/06
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Sexual Functioning in Long-term Treatment of MDD: Duloxetine, Escitalopram,
and Placebo - Doctor's Guide, 5/23/06 -
"the study found a statistically
significant worsening of sexual functioning as measured by the Changes in
Sexual Functioning Questionnaire (CSFQ) for escitalopram versus placebo at 4
weeks (P </=.01) while duloxetine was not statistically different from
placebo"
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FDA OKs Generic
Depression Drug - WebMD, 5/23/06
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Review Shows Escitalopram Prevents Relapse of Anxiety, Depression -
Doctor's Guide, 3/27/06
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Bupropion and Escitalopram Provide Similar Relief in Depressed Patients
- Medscape, 10/28/05
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For Major Depression, Escitalopram (Lexapro) Achieves Better Risk/Benefit
Profile Than Venlafaxine XR (Effexor XR) - Doctor's Guide, 5/31/05
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Escitalopram Shows Efficacy in Depressed Patients With Comorbid Anxiety
- Doctor's Guide, 5/27/05
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Escitalopram Effective in Comorbid Social Anxiety Disorder and Major
Depression - Doctor's Guide, 3/23/05
- Escitalopram in Adolescent Major Depression - Medscape, 1/31/05
- Cipralex (Escitalopram) Appears to be at Least as Effective, Faster Acting and Better Tolerated Than is Venlafaxine in Treating Major Depressive Disorder - Doctor's Guide, 10/11/04
- Cipralex (Escitalopram) Appears to be Superior to Both Placebo and Paroxetine in Treatment of General Anxiety Disorder - Doctor's Guide, 10/11/04
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Escitalopram Effective for Long-Term Treatment of GAD - Clinical Psychiatry News, 9/04
- Continuation Treatment with Escitalopram Effective in Preventing Relapse Into An Episode Of Major Depressive Disorder - Doctor's Guide, 2/25/04
- FDA Approves Treatment for GAD - Physician's Weekly, 1/26/04
- Lexapro (Escitalopram Oxalate) Receives FDA Approval FOR Treatment OF Generalized Anxiety Disorder - Doctor's Guide, 12/18/03
- Lexapro (Escitalopram Oxalate) Starting Dose Appears As Effective As Optimally Dosed Zoloft (Sertraline) In Treatment Of Major Depressive Disorder - Doctor's Guide, 12/15/03
- Faster Onset, Higher Response Rate With Escitalopram Than Racaemic Counterpart - Doctor's Guide, 10/13/03
- FDA Grants Approvable Letter for Lexapro (Escitalopram Oxalate), Treatment of Generalized Anxiety Disorder - Doctor's Guide, 9/29/03
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Try Mirtazapine or Escitalopram for Speedy Onset - Clinical Psychiatry News, 8/03 -
"When you need
the quickest possible antidepressant effect, consider choosing mirtazapine or escitalopram for treatment or combining a selective serotonin reuptake inhibitor with
pindolol
or olanzapine"
- Significant Quality Of Life Improvements Seen In Patients With Generalised Anxiety Disorder Treated With Escitalopram - Doctor's Guide, 4/1/03
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Consider Escitalopram First For Severe Major Depression - Clinical Psychiatry News, 4/03
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Escitalopram Tx Leads to Remission in GAD - Clinical Psychiatry News, 4/03
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Escitalopram Effective, Well Tolerated Depression Tx in Primary Care Setting - Clinical Psychiatry News, 4/03
- Escitalopram Effective in Social Anxiety Disorder for Up to 36 Weeks - Doctor's Guide, 3/31/03
- Escitalopram Beneficial for Treating Various Anxiety Disorders - Doctor's Guide, 3/31/03
- Lexapro (Escitalopram Oxalate) Oral Solution Formulation Provides New Option for Depressed Patients - Doctor's Guide, 12/02/02
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Escitalopram Works for Anxiety Disorders, Panic - Clinical Psychiatry News, 11/02
- Escitalopram Shows "Strong and Early Efficacy" for Major Depression in Acute Phase - Doctor's Guide, 10/10/02
- Lexapro Bests Effexor in Depression Study - WebMD, 10/9/02
- Escitalopram Remission Reaches 86 Percent at One Year For Responders With Moderate or Severe Depression - Doctor's Guide, 10/9/02
- Escitalopram Achieves Earlier Response and Better Tolerability than Venlafaxine XR in First Head-to-Head Study - Doctor's Guide, 10/8/02
- Lexapro (Escitalopram Oxalate) Is Now Available In Pharmacies Nationwide For The Treatment Of Major Depressive Disorder - Doctor's Guide, 9/5/02
- Escitalopram Effective as First-Line Treatment of Severe Depression - Doctor's Guide, 9/2/02
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FDA Approves Escitalopram for Major Depression - Clinical Psychiatry News, 9/02
- Lexapro (Escitalopram Oxalate) Approved As Maintenance Treatment For Major Depressive Disorder - Doctor's Guide, 8/29/02
- Lower Depression Relapse, Continued Improvement Seen With Continued Escitalopram - Doctor's Guide, 8/29/02
- Escitalopram Safe and Effective for Patients Switched from Citalopram to Escitalopram - Doctor's Guide, 8/29/02
- Escitalopram Safe, Effective in the Treatment of Generalized Anxiety Disorder - Doctor's Guide, 8/29/02
- New Antidepressant Awaited, But Little Proof It's Much Better - Intelihealth, 8/27/02
- New Antidepressant [Lexapro] Approved - WebMD, 8/16/02
- Researchers laud new antidepressant - CNN, 8/15/02
- Lexapro(TM), The Single-Isomer of Celexa(TM), Receives FDA Approval For the Treatment of Major Depression - Doctor's Guide, 8/15/02
- Escitalopram Shows Promise for Treatment of Panic Disorder - Doctor's Guide, 6/28/02
- Escitalopram Superior to Citalopram for Severe Depression - Doctor's Guide, 6/27/02
- Escitalopram Improves Depression In Patients Treated In Primary Care - Doctor's Guide, 5/30/02
- Escitalopram Is a Well Tolerated Selective Serotonin Reuptake Inhibitor - Doctor's Guide, 5/23/02
- Study Results Published In International Clinical Psychopharmacology Show Escitalopram Effectively Treats Depression In Primary Care Settings - Doctor's Guide, 4/27/02
- The Journal Of Clinical Psychiatry Reports Escitalopram Effective And Well Tolerated - Doctor's Guide, 4/26/02
- Lexapro (Escitalopram) Significantly More Effective Than Placebo in Social/Generalized Anxiety and Panic Disorders -
Doctor's Guide, 3/22/02
- FDA Issues Approvable Letter for Lexapro (Escitalopram) for Major Depressive Disorder - Doctor's Guide, 1/24/02
- Escitalopram and Citalopram Appear Safe, Effective for Depression - Doctor's Guide, 7/5/01
- Escitalopram Shows Promise For Treatment of Major Depressive Disorder - Doctor's Guide, 5/9/01 -
"a single isomer of citalopram and a more potent and selective serotonin reuptake inhibitor (SSRI)"
- Escitalopram, New Generation Selective Serotonin Reuptake Inhibitor, Promising In Major Depressive Disorder - Doctor's Guide, 12/13/00
Abstracts:
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A
Markov cost-utility analysis of escitalopram and duloxetine for the
treatment of major depressive disorder - Curr Med Res Opin. 2008 Mar 7 -
"quality adjusted life weeks (QALWs) ... This
analysis suggests that escitalopram was more effective in terms of QALWs and
less costly than duloxetine for treatment of depression" - See
escitalopram at
OffshoreRX.com
 .
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Which antidepressants have demonstrated superior efficacy? A review of the
evidence - Int Clin Psychopharmacol. 2007 Nov;22(6):323-329 -
"Criteria were defined to judge the strength of
evidence. Two pivotal studies in moderate-to-severe major depressive
disorder that demonstrate superiority on the primary efficacy measure, or
alternatively one pivotal study supported by consistent results from
meta-analyses, was considered to constitute evidence for definite
superiority. Three antidepressants met these criteria: clomipramine,
venlafaxine, and escitalopram. Three antidepressants were found to have
probable superiority: milnacipran, duloxetine, and mirtazapine. Only
escitalopram was found to have definite superiority in the treatment of
severe depression; probable superiority was identified for venlafaxine and
possible superiority for milnacipran and clomipra"
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Escitalopram versus venlafaxine XR in the treatment of
depression - Int Clin Psychopharmacol. 2006
Sep;21(5):297-309 - "treatment with
20 mg/day escitalopram resulted in a statistically significantly (P<0.05)
higher remission rate at week 8 (47%) than treatment with venlafaxine XR
(29%) ... The relative benefit of escitalopram versus venlafaxine XR was
1.46, indicating that a patient was more likely to benefit from treatment
with escitalopram. The proportions of patients who withdrew owing to adverse
events were 7.5% in the escitalopram group and 11.2% in the venlafaxine XR
group" - See
Escitalopram 20mg (Generic Equivalent of Lexapro 20mg)
- OffshoreRx.com.
-
A comparative study of the efficacy of long-term treatment with escitalopram
and paroxetine in severely depressed patients - Curr Med Res Opin. 2006
Jul;22(7):1331-41 - "Escitalopram is
significantly more effective than paroxetine in the long-term treatment of
severely depressed patients"
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Comparison of the Effects of Citalopram and Escitalopram on 5-Ht-Mediated Neuroendocrine Responses - Neuropsychopharmacology. 2004 May 5 -
"both citalopram and escitalopram increased salivary and plasma cortisol levels with no evidence of consistent differences between them"
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