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Home > Anti-aging Research > HRT > CombiPatch
CombiPatch
Related Topics:
- HRT in general / Female Sexuality / hot flashes / PMS / menopause /
contraception / osteoporosis
- Conjugated estrogens - Cenestin / Estrace / Ogen / Premarin
- Esterified estrogens - Menest
- Estrogen (estradiol) patches - Alora / Climara / Estraderm / Vivelle / Menostar
- Vaginal estrogen - Estring / Premarin
- Combination estrogen and methyltestosterone - Estratest
- Medroxyprogesterone - Cycrin / Provera
- Estrogen progestin tablets - Activella / Femhrt / Prempro
- Estrogen and progesterone patch - Combipatch
- Estrogen cream - Estrasorb
- Drospirenone and estradoil - Yasmin
/ Angeliq
- Transdermal - EstroGel® (estradiol gel)
/ Elestrin™/Bio-E-Gel® (estradiol gel)
Where to purchase:
General Information:
News & Research:
-
Renin Substrate Levels Decrease with Transdermal Hormone Therapy and Increase with Oral Hormone Therapy - Doctor's Guide, 5/6/03 -
"Oral
Prempro (conjugated equine estrogen/medroxyprogesterone) appears to increase plasma levels of renin substrate (angiotensinogen) to a significantly greater extent than CombiPatch (estradiol/norethindrone) ... The problem is that increases in the renin substrate (RS) can trigger activity in [renin-angiogenesis-aldosterone
system] that can lead, in turn, to higher blood pressure and, possibly, hypertension"
- Transdermal Hormones Better than Oral for Improving Women's Sexual Quality of Life - Doctor's Guide, 5/2/03 -
"At end point (20 weeks), 33% of
81 women on CombiPatch eported improvement in Quality of Life scores compared to 17% of 84 on Prempro"
- Hormone Studies: What Went Wrong? - NY Times, 4/22/03 -
"He said it was possible that estradiol, the estrogen women naturally produce and
that goes directly to their bloodstream is protective. The estrogen in pills, metabolized by the liver before entering the blood, may be harmful. Neither the nurses' study nor the Women's Health Initiative addressed that question, Dr. Rossouw said"
- Estrogen Patch Compared To Pill Minimizes Cardiovascular Risk Factor In Postmenopausal Women - Doctor's Guide, 4/15/03
- Estrogen Patch More Heart-Friendly Than Pills - WebMD, 4/15/03 -
"the C-reactive protein increased to an average
of almost twice their baseline levels when the women took oral estrogen replacement, but not when they were on the estrogen patch"
-
Transdermal Estradiol May Be An Effective Antidepressant - Clinical Psychiatry News, 1/03 -
"The
response to transdermal estradiol was “quite rapid,” compared with conventional antidepressants ... Moreover, transdermal estradiol's antidepressant effect remained significant during the 4-week washout period
at the end of the 12-week study period"
- Estradiol Alone Does Not Increase Breast Cancer Risk - Doctor's Guide, 12/16/02 -
"Hormone replacement therapy containing progestins
significantly elevates breast cancer risk, but preparations containing estradiol alone do not, a large Swedish observational study suggests"
- Nonoral HRT May Be Safer Alternative - WebMD, 10/10/02 -
"Investigators conducting a small European study in which HRT was given in the form of estrogen
skin patches and vaginally administered natural progesterone say these methods may be free of the cardiovascular risks that have recently been associated with oral hormone therapy. As an added benefit, postmenopausal women who were on the regimen for one year lost weight, lowered their blood pressure, and had less
vaginal bleeding ... the weight loss and the decreases in blood pressure may have been associated with the use of natural progesterone in the HRT regimen, rather than the synthetic form of the hormone that is commonly used"
- CombiPatch Now Available In U.S. For Menopause Symptoms - Doctor's Guide, 9/30/98
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