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Home > Anti-aging Research > Anti-depressants > Depacon
Depacon® (valproate)
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News & Research:
- valproate at drugstore.com
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Depacon (valproate
sodium) - rxlist.com
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Epilepsy Drugs May Cause Sexual Disorders - Science Daily, 10/29/07
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Epilepsy Drug Linked to Low IQ - WebMD, 5/3/07
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Epilepsy Drug Poses High Risk for Fetal Death and Birth Defects -
Doctor's Guide, 8/8/06
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Weight and Cholesterol Gains Greater with Valproate than with Lamotrigine in
Epileptic Women - Doctor's Guide, 12/8/05
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Epilepsy Drug Linked to Birth Defects, Low IQ - WebMD, 3/21/05
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Valproate Use Related to PCOS In 10% of Bipolar Women - Clinical Psychiatry News, 1/05
- Bipolar Alcoholics Helped by Seizure Drug - Intelihealth, 1/4/05
- Epilepsy Drug Linked to Lower IQ - WebMD, 10/13/04
- Valproate Use May Lead to Polycystic Ovarian Syndrome - Doctor's Guide, 6/18/04
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Sodium Valproate Appears Effective for Aggressive Behaviour in Demented Patients with Extended Treatment - Doctor's Guide, 4/28/04
- Carbamazepine, Oxcarbazepine, and Valproate Reduce Serum Thyroid Hormone Concentrations in Female Adolescents - Doctor's Guide, 3/23/03
- Epilepsy Drug May Slow Progression Of Alzheimer’s - Psychiatric News, 3/5/04
- Women Gain Weight with Valproate, But Not with Lamotrigine - Doctor's Guide, 5/6/03
- No Sign That Valproate Affects Thyroid Or Parathyroid Function In Children - Doctor's Guide, 3/18/03
- Valproate Linked To Hyperinsulinemia And Dyslipidemia In Obese Men - Doctor's Guide, 3/18/03
- No Link Found Between Valproate And Weight Gain In Prepubescent Children With Epilepsy - Doctor's Guide, 3/3/03
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Valproate Tied to Highest Rate of Birth Defects - Clinical Psychiatry News, 2/03
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Newer Anticonvulsants Seem Well Tolerated, but Carry Other Risks - Clinical Psychiatry News, 2/03
- Clinical Signs Of Hyperandrogenism With Valproate More Common In Epilepsy Patients Than Bipolar Patients - Doctor's Guide, 2/10/03
- Generalized Epilepsy And Use Of Valproate Linked To Reproductive Dysfunction - Doctor's Guide, 12/19/02
- Lamotrigine Linked To More Quality Of Life Improvements Than Valproate In Epilepsy Patients - Doctor's Guide, 11/1/02
- Olanzapine Plus Lithium or Valproate Effective for Bipolar Relapse Prevention - Doctor's Guide, 5/22/02
- Anticonvulsant, Valproate (Divalproex), Possible Treatment Option for Alcohol Withdrawal Syndrome - Doctor's Guide, 9/17/01
- Antiepileptic, Valproate, Associated With Weight Gain - Doctor's Guide, 2/7/01
- Fewer Side Effects With Depakote (Divalproex) Than With Olanzapine For Acute Mania - Doctor's Guide, 12/12/00 -
"The following adverse events showed a statistically significant difference: edema (0 percent
vs. 14 percent), somnolence (29 percent vs. 47 percent), speech disorder (0 percent vs. 7 percent), rhinitis (3 percent vs. 14 percent) and weight gain (10 percent vs. 25 percent), in the Depakote- and olanzapine-treated groups respectively ... Depakote patients had significantly less weight gain than olanzapine
patients ... Cases of life-threatening pancreatitis, some rapidly progressing to death, have been reported in both adults and children receiving valproate. The frequency of adverse effects, particularly elevated liver enzymes and thrombocytopenia may be dose-related. Valproate may produce teratogenic effects in the
offspring of women receiving the drug during pregnancy. Depakote (divalproex sodium) is a derivative of valproic acid"
- Rapid infusion valproate sodium safe and effective for epilepsy - Doctor's Guide, 5/1/00
- Valproate Effective In Stopping Persistent Migraine - Doctor's Guide, 6/25/99
- Folate May Not Be Recommended In Women Taking Anti-Epileptics - Doctor's Guide, 4/23/99 -
"Expectant mothers who were taking more than one anti-epileptic drug -- valproate and
carbamazepine in particular -- had a 22 percent risk of having a child with birth defects"
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