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Home > Anti-aging Research > Antidepressants & Psychotropics > Duloxetine

Cymbalta (duloxetine)

Related Topics:

• Anafranil (clomipramine) / Auroix (moclobemide) / Buspar (buspirone) / Celexa (citalopram) / Cymbalta (duloxetine) / ECT / Edronax (reboxetine) / Effexor (venlafaxine) / gepirone / Lexapro (escitalopram) / Luvox (fluvoxamine) / Paxil (paroxetine) / Pristiq (desvenlafaxine) / Prozac (fluoxetine) / Remeron (mirtazapine) / RU-486 (mifepristone) / Serzone (nefazodone) / tianeptine / tricyclics / Wellbutrin (bupropion) / Zoloft (sertraline)

• St. John's wort / 5-HTP / SAMe / NADH / Omega-3 / tyrosine / acetyl-l-carnitine / DHEA / phenylalanine / ginkgo / phosphatidylserine / folate / antidepressants

Alternative News:

• St. John's Wort and Duloxetine Equally Effective in Mild to Moderate Depression - Doctor's Guide, 9/1/08 - "Twenty patients received St. John's Wort at a dosage of 900 mg QD, whereas the remaining 20 participants were treated with duloxetine 60  30 mg QD ... In the group of patients suffering from moderate depression, we did not find any statistically significant differences between the 2 treatment groups" - See St. John's wort products at iHerb.

News & Research:

• Cymbalta (duloxetine Hcl) - rxlist.com
• Study: Cymbalta May Cut Chronic Low Back Pain - WebMD, 8/26/08
• Cymbalta Approved for Fibromyalgia - Medscape, 6/20/08
• Duloxetine Does Not Relieve Painful Physical Symptoms In Depression, According To Current Analysis - Science Daily, 1/21/08
• FDA Approves Cymbalta® for Maintenance Treatment of Major Depressive Disorder - Doctor's Guide, 11/30/07
• Recent Trials in Generalised Anxiety Disorder Highlight Escitalopram, Duloxetine, and Anticonvulsants - Doctor's Guide, 11/21/07
• Duloxetine May Improve Patients' Sleep Quality - Clinical Psychiatry News, 11/07
• Duloxetine Improves Functioning and Quality of Life in Patients with Anxiety Disorder - Doctor's Guide, 4/3/07
• Duloxetine is Effective for Anxiety - Doctor's Guide, 4/2/07
• FDA Approves Duloxetine for Anxiety - Clinical Psychiatry News, 3/07
• Duloxetine May Alleviate Both Pain and General Anxiety Disorder - Doctor's Guide, 2/12/07
• Duloxetine Treatment of Neuropathic Pain May Affect Glycemic Control - Medscape, 1/3/07
• Duloxetine Safe for Long-Term Management of Diabetic Peripheral Neuropathic Pain - Doctor's Guide, 6/28/06
• Duloxetine May Impair Metabolic Control in Patients With Diabetic Neuropathic Pain - Doctor's Guide, 6/12/06
• Sexual Functioning in Long-term Treatment of MDD: Duloxetine, Escitalopram, and Placebo - Doctor's Guide, 5/23/06 - "the study found a statistically significant worsening of sexual functioning as measured by the Changes in Sexual Functioning Questionnaire (CSFQ) for escitalopram versus placebo at 4 weeks (P </=.01) while duloxetine was not statistically different from placebo"
• Lilly Submits Supplemental New Drug Application for Generalized Anxiety Disorder - Doctor's Guide, 5/9/06
• Patients Taking Cymbalta Also Reported Reduced Painful Physical Symptoms and Improved Functioning - Doctor's Guide, 3/24/06
• Duloxetine Improves Functional Outcomes in Diabetic Neuropathic Pain - Doctor's Guide, 3/2/06
• Duloxetine Reduces Fibromyalgia Pain - Doctor's Guide, 2/27/06
• Study Finds Cymbalta as Safe and Well-Tolerated as Routine Drug Treatments for Diabetic Nerve Pain - Doctor's Guide, 2/14/06
• Duloxetine Lifts Arthritis Pain, Aids Cognition - Clinical Psychiatry News, 1/06
• Duloxetine: A Balanced and Selective Norepinephrine and Serotonin-Reuptake Inhibitor - Medscape, 12/14/05
• New Study Suggests Cymbalta (Duloxetine Hydrochloride) Reduced Depression Symptoms at Least as Fast As a Leading Competitor - Doctor's Guide, 12/13/05
• Duloxetine Improves Cognition in Elderly Patients with Major Depressive Disorder - Doctor's Guide, 11/10/05
• Liver Damage Data Prompt New Alert on Duloxetine Label - Clinical Psychiatry News, 11/05
• FDA Issues Liver Warning for Cymbalta - WebMD, 10/17/05
• Duloxetine (Cymbalta) Treatment for Diabetic Peripheral Neuropathic Pain Shows Efficacy at Week 1: Presented at ADA - Doctor's Guide, 6/15/05
• Duloxetine (Cymbalta) Improves Depression and Cognition Measures in Depressed Elderly - Doctor's Guide, 5/31/05
• Duloxetine (Cymbalta) Effective for Women With Fibromyalgia, With or Without Comorbid Depression - Doctor's Guide, 5/30/05
• Duloxetine (Cymbalta) Appears Effective for Comorbid Anxiety in Geriatric Depression - Doctor's Guide, 5/26/05
• Duloxetine Appears Safe for Hypertensive Patients With Diabetic Neuropathic Pain - Doctor's Guide, 5/18/05
• Duloxetine Reduces Diabetic Neuropathic Pain, Even Without Comorbid Depression - Doctor's Guide, 2/28/05
• FDA Approves Duloxetine in Speedy Review - Clinical Psychiatry News, 11/04
• Yentreve (Duloxetine) Appears to Reduce Frequency of Urinary Incontinence Episodes in Women - Doctor's Guide, 9/24/04
• Duloxetine Effective in Fibromyalgia - Medscape, 9/10/04
• Antidepressant Duloxetine Aids in Improving Symptoms, Relieving Pain in Fibromyalgia - Doctor's Guide, 9/9/04
• FDA Grants Priority Approval to Antidepressant Cymbalta (Duloxetine) to Treat Diabetic Peripheral Neuropathic Pain - Doctor's Guide, 9/7/04
• Duloxetine Gains FDA Approval for Major Depression - Clinical Psychiatry News, 9/04
• Duloxetine (Yentreve) Significantly Improves Stress Urinary Incontinence - Doctor's Guide, 8/26/04
• Cymbalta (Duloxetine), Treatment for Major Depression, Now Available in US - Doctor's Guide, 8/26/04 - "Cymbalta® (duloxetine HCl; pronounced SIM-BALL-TA), a new treatment for major depression, is now available by prescription in pharmacies across the United States"
• New Antidepressant Cymbalta (Duloxetine) Launched in US - Doctor's Guide, 8/24/04
• FDA Approves Cymbalta (Duloxetine) for Treatment of Depression - Doctor's Guide, 8/4/04 - "Cymbalta, a balanced and potent reuptake inhibitor of serotonin and norepinephrine"
• Duloxetine Appears to Improve Stress Urinary Incontinence in Women - Doctor's Guide, 7/29/04
• Duloxetine Effective for Diabetic Neuropathic Pain - Clinical Psychiatry News, 6/04
• Duloxetine Benefits Women With Fibromyalgia - Clinical Psychiatry News, 6/04
• Duloxetine May Be Effective for Treatment of Fibromyalgia Symptoms - Doctor's Guide, 3/5/04
• Duloxetine May Be Effective for Treatment of Pain Associated With Diabetic Neuropathy - Doctor's Guide, 3/5/04
• Cymbalta (Duloxetine) Demonstrates High Tolerability, Safety In Long-Term Study - Doctor's Guide, 11/20/03
• New Global Study of Duloxetine Effect on Stress Incontinence Supports Earlier Studies' Efficacy Findings - Doctor's Guide, 10/14/03
• Higher Depression Remission Rates With Duloxetine Than Selective Serotonin Reuptake Inhibitors - Doctor's Guide, 10/13/03
• Duloxetine Appears to Ease Pain of Diabetic Neuropathy - Clinical Psychiatry News, 10/03
• Duloxetine Treatment Causes Women with Severe Stress Urinary Incontinence to Reconsider Surgery - Doctor's Guide, 9/16/03
• Duloxetine Achieves Short- and Long-Term Improvement of Stress Urinary Incontinence - Doctor's Guide, 9/15/03
• Duloxetine Safe, Effective in Stress Urinary Incontinence - Medscape, 9/12/03
• Duloxetine Shows Promise in Depression, Pain Management - Clinical Psychiatry News, 9/03
• Duloxetine Relieves Pain Associated With Diabetic Neuropathy - Doctor's Guide, 8/26/03
• Higher Rates Of Remission, Lower Incidence Of Sexual Dysfunction Demonstrated In Patients Taking Cymbalta (Duloxetine) - Doctor's Guide, 6/3/04
• Venlafaxine Beats Selective Serotonin-Reuptake Inhibitors in Remission of Depression - Doctor's Guide, 5/22/03 - "The results of this largest-of-all comparative study of venlafaxine and other agents supports the conclusions of other investigators that, compared to other SSRIs, venlafaxine helps patients achieve remission of symptoms at relatively higher rates" - Note:  Venlafaxine increases both serotonin and norepinephrine, as does mirtazapine and the investigational drug duloxetine.
• Duloxetine Appears to Relieve Pain In Patients With Depression - Clinical Psychiatry News, 5/03
• New Antidepressants Target Aches and Pains, Too - Psychiatric News, 4/18/03
• Investigative Duloxetine Helps Physical Pain in Depression, Ups Remission Rate - Doctor's Guide, 2/20/03
• Duloxetine Resolves Pain in Depressed Patients - Doctor's Guide, 2/21/03
• Duloxetine Antidepressant Action Begins in One Week - Medscape, 11/12/02
• New Antidepressant [Cymbalta] Works Faster - WebMD, 11/11/02 - "Cymbalta affects two different brain chemical messengers -- serotonin and norepinephrine"
• Duloxetine Effective and Safe in Treatment of Major Depression in Elderly - Doctor's Guide, 11/4/02
• Antidepressant Duloxetine Considered ‘Approvable’ by FDA - Clinical Psychiatry News, 10/02
• Novel Antidepressant Therapies Near Approval - Clinical Psychiatry News, 10/02
• Meta-Analysis Shows Duloxetine Safe and Tolerable for Major Depression - Doctor's Guide, 9/25/02
• Duloxetine 60mg Once Daily Efficacious For Emotional and Physical Symptoms of Depression - Doctor's Guide, 9/24/02
• Duloxetine Controls Symptoms of Stress Urinary Incontinence - Medscape, 7/23/02
• Drug Shows Promise for Bladder Problems - WebMD, 7/22/02
• Duloxetine Has Little Effect on Body Weight - Doctor's Guide, 5/24/02
• Duloxetine Effective Against Emotional and Physical Symptoms of Depression - Doctor's Guide, 5/21/02
• Duloxetine Dampens Depression, Comorbid Pain - Clinical Psychiatry News, 2/02
• Duloxetine Shown to Significantly Reduce Symptoms of Depression, Including Physical Symptoms - Doctor's Guide, 11/19/01
• Duloxetine Shows Efficacy for Stress Urinary Incontinence - Doctor's Guide, 10/29/01

Abstracts:

• A Markov cost-utility analysis of escitalopram and duloxetine for the treatment of major depressive disorder - Curr Med Res Opin. 2008 Mar 7 - "quality adjusted life weeks (QALWs) ... This analysis suggests that escitalopram was more effective in terms of QALWs and less costly than duloxetine for treatment of depression" - See escitalopram at OffshoreRX.com.
• Evidence for the efficacy of duloxetine in treating mild, moderate, and severe depression - Int Clin Psychopharmacol. 2007 Nov;22(6):348-55
• Which antidepressants have demonstrated superior efficacy? A review of the evidence - Int Clin Psychopharmacol. 2007 Nov;22(6):323-329 - "Criteria were defined to judge the strength of evidence. Two pivotal studies in moderate-to-severe major depressive disorder that demonstrate superiority on the primary efficacy measure, or alternatively one pivotal study supported by consistent results from meta-analyses, was considered to constitute evidence for definite superiority. Three antidepressants met these criteria: clomipramine, venlafaxine, and escitalopram. Three antidepressants were found to have probable superiority: milnacipran, duloxetine, and mirtazapine. Only escitalopram was found to have definite superiority in the treatment of severe depression; probable superiority was identified for venlafaxine and possible superiority for milnacipran and clomipra"
• A randomized, double-blind comparison of duloxetine and venlafaxine in the treatment of patients with major depressive disorder - J Psychiatr Res. 2007 Apr 17 - "were no significant differences between duloxetine 60mg/day and venlafaxine 150mg/day as measured by GBR assessment at the end of 6 weeks (-1.418 vs. -1.079, P=0.217) or 12 weeks ... Nausea was the most common treatment-emergent adverse event (TEAE) for both drugs, and was significantly higher with duloxetine 60mg/day compared to venlafaxine 150mg/day during the first 6 weeks of treatment"
• Duloxetine in the treatment of depression: a double-blind placebo-controlled comparison with paroxetine - J Clin Psychopharmacol. 2004 Aug;24(4):389-99 - "Duloxetine 80 mg/d was superior to placebo for most other measures, including overall pain severity, and was superior to paroxetine on 17-item Hamilton Depression Rating Scale improvement (by 2.39 points; 95% CI 0.14, 4.65; P = 0.037) and estimated probability of remission"

Related Searches:

• Doctor's Guide search of duloxetine
• Doctor's Guide (2) search of duloxetine
• Drugstore.com search of duloxetine
• Life Extension Foundation search
• Medline search of duloxetine
• Medscape search of Cymbalta or duloxetine
• Google search of duloxetine
• Nutrition Science News search
• RxList information on duloxetine
• WebMD search of duloxetine

Related Sites:

• Inside Cymbalta Home
• Books on depression at Amazon.com

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