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Welcome to the Quality Counts. For those health conscious consumers and medical professionals that are looking to purchase nutritional supplements, vitamins, herbs, learning about medications, losing weight, health food, low carbs, high protein nutrition, and exercise, you have come to the right place. Quality Counts serves both the medical practitioner and consumer interested in nutritional therapy and alternative medicine.
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Anti-aging Research > Proscar/Propecia
Proscar (5 mg) Propecia(TM) (1 mg) (finasteride hydrochloride)
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Alternative News:
- See saw palmetto
- Relieve Common Men’s Condition with Saw Palmetto Extract - Healthwell Exchange Daily News, 9/16/04 -
"Comparison trials found its effects to be similar to those of finasteride and tamsulosin ... however,
while some men using the standard medications experienced sexual dysfunction as a side effect, men using the herbal extract did not" - See
iHerb
or
Vitacost
saw palmetto products.
News & Research:
-
Finasteride and High-Grade Prostate Cancer - Medscape, 6/19/08 -
"A new analysis from the national Prostate Cancer
Prevention Trial (PCPT) shows that finasteride does not increase the risk
for high-grade prostate cancer, as earlier findings appeared to indicate"
-
Proscar Lowers Prostate Cancer Risk in All Men - Medscape, 6/13/08 -
"Finasteride (Proscar) reduces the risk of prostate
cancer regardless of a patient's risk level for the malignancy ... In the
Prostate Cancer Prevention Trial, finasteride treatment was associated with
a 25% reduction in the risk of prostate cancer"
-
Finasteride May Help Preventing Prostate Cancer, Study Shows - Science
Daily, 5/18/08 - "in addition to a 25 to 30 percent
reduction in prostate cancer development overall in men taking finasteride,
there was no evidence that the drug increased the rate of aggressive tumors
and likey decreased their rate by 27 percent"
-
Pros, Cons Of Drug Proven To Prevent Prostate Cancer Should Be Considered,
Researchers Recommend - Science Daily, 1/21/08 -
"Finasteride is currently the only drug that has been shown to prevent
prostate cancer in a large in addition to preventing prostate cancer,
finasteride also reduces urinary-tract symptoms associated with benign
prostatic hyperplasia. It also decreased sexual desire and caused impotence
in 5 percent of the trial participants ... randomized trial but is used for
this purpose in very few men"
-
Diet
And Medications May Assist Prevention Of Prostate Cancer - Science
Daily, 9/24/07 - "dutasteride, has reduced by 50
percent the number of cancerous biopsies among men with benign prostatic
hypertrophy ... In one study of selenium, the incidence of prostate cancer
was reduced by 49 percent over ten years ... Data already suggests novel
uses of statins, commonly prescribed cholesterol-lowering agents, and
insulin modulating drugs, such as metformin or the glitazones" - See
dutasteride at
OffshoreRX.com
.
-
Diet, Drugs May Stop Prostate Cancer - WebMD, 9/24/07
-
Drug
That Reduces Prostate Size And Cancer Risk Also Improves Early Detection
- Science Daily, 9/11/07 - "Men now have another
good reason to consider taking finasteride, a well-known generic drug that
shrinks an enlarged prostate and reduces the risk of getting prostate cancer
by 25 percent ... finasteride also raises the odds that physicians will find
fast-growing prostate cancers early, when they are most easily treatable"
-
Prostate Cancer Prediction Not Skewed by Finasteride - Medscape, 7/30/07
- "with the exception of the approximate reduction
of PSA by half with finasteride, the impact of these risk factors is similar
to men who do not receive finasteride"
-
Prostate Drug Doesn't Limit Sexual Function In Most Men - Science Daily,
7/19/07 - "The study suggests that finasteride will
cause little or no sexual dysfunction for most men who decide to take it"
-
Prostate Drug May Not Dim Sex - WebMD, 6/26/07 -
"Six months after the men started taking their assigned drugs, the survey
scores were about three points higher for the men taking Proscar. By the end
of the study, that gap narrowed to about two points"
-
Hair-Loss Drug Alters Cancer Test - WebMD, 12/7/06 -
"We found that Propecia does exactly
the same thing as Proscar -- it cuts PSA in half after you use it for a year
... Unfortunately, cutting PSA in half doesn't mean that cancer risk is cut
in half ... Instead, it means men on Propecia may have an unseen problem"
-
Hair-Growth Drug Artificially Lowers PSA Levels in Prostate Cancer Screening
- Doctor's Guide, 12/5/06 - "When
doctors ask for their patients' medical history, they need to ask if they
have taken any drugs for hair loss, and the doctors need to multiply the PSA
readings by two"
-
Finasteride as a Chemopreventive Agent in Prostate Cancer - Medscape,
9/15/06 - "Prostate cancer was
detected in 803 of 4,368 men (18.4%) taking finasteride as opposed to 1,147
of the 4,692 men (24.4%) in the placebo group (P <0.001). This was a 24.8%
relative risk reduction in prevalence of prostate cancer during the trial
,,, The PCPT has shown finasteride to be an effective chemopreventive agent
in low-grade prostate cancer"
-
Drug May Fight Women's Hair Loss, Too - WebMD, 3/20/06 -
"Propecia, a drug used to treat male
hair loss, may help fix women's hair loss when taken with birth control
pills"
-
Analysis Shows Drug Could Save Lives From Prostate Cancer
- Science Daily, 3/16/05 - "the commonly used drug finasteride reduced the incidence of
prostate cancer by 24.8 percent compared to a placebo. However, a possible
increase in the number of high-grade tumors in the trial prompted many to
question whether any benefits of the drug would be offset by an increase in
mortality related to the higher-grade tumors. No difference in mortality was
seen during the 7 years of PCPT"
- Prostate Cancer Drug Has Lifesaving Potential - WebMD, 2/28/05
- Finasteride Promising Treatment to Reduce Incidence of Prostate Cancer - Doctor's Guide, 2/28/05
- Sexual Adverse Effects Uncommon With Finasteride - Medscape, 7/19/04 -
"Sexual adverse effects from the use of 1 mg of finasteride for the treatment of
alopecia are not common"
- Testosterone Plus Finasteride Improves BMD in Men With Low Testosterone - Medscape, 2/25/04 -
"The combination of testosterone (T) and finasteride (F) improves bone mineral density
(BMD) in men with low T levels without increasing prostate-specific antigen (PSA) levels"
- Finasteride Treatment Associated with Lower Incidence of Prostate Cancer, But Also Higher Risk of High-Grade Disease and Sexual Dysfunction - Doctor's Guide, 10/20/03
- 2 in 1: Drug Works Against Baldness and Cancer - Physician's Weekly, 7/21/03
- Does Finasteride Prevent Prostate Cancer? - Medscape, 7/18/03
-
Hair-Loss Drug Prevents Prostate Cancer - HealthDay, 7/16/03
- Public Forum Participants Cautiously Optimistic on New Finasteride Data - Doctor's Guide, 7/14/03
- Finasteride Reduced Prevalence of Prostate Cancer, But Not Without Risks - Doctor's Guide, 6/25/03
- Proscar for Prostate Cancer Prevention: Q&A - WebMD, 6/24/03 -
"a drug called Proscar can also prevent or delay prostate
cancer. It also shows that the drug may increase the risk of aggressive, high-grade prostate tumors. And while men taking Proscar have fewer urinary problems, they also have more sexual problems"
-
Drug [finasteride] Prevents Prostate Cancer - HealthDay, 6/24/03
- Drug Prevents Prostate Cancer - WebMD, 6/24/03
- Men With Benign Prostate Hyperplasia, Obstruction Symptoms, Can Switch From Alpha-Blocker To Finasteride - Doctor's Guide, 5/5/03
- Sexual Adverse Events From Finasteride Most Prominent First Year - Medscape, 4/7/03
- Monthly Updates - Hair Loss Research, 10/01 -
"While finasteride (Propecia/Proscar) decreases serum DHT, it also is thought to increase estrogen which suggests
that men over 35 may want to consider using it in conjunction with a systemic aromatase inhibitor such as Chrysin/Piperine
(Super Miraforte), Arimidex,
or stinging nettle extract, to maximize its hair growth effects and minimize potential side effects (that are listed in the PDR) such as
Gynocaemastia (breast enlargement in males), sexual side effects, and an increase in fat deposition. These compounds have been reliably shown to increase testosterone and reduce excess estrogen, resulting
in a youthful hormone profile that optimizes immune function and to some degree, body composition"
Abstracts:
-
Does
the level of prostate cancer risk affect cancer prevention with finasteride?
- Urology. 2008 May;71(5):854-7 - "Finasteride
significantly reduced prostate cancer risk for all risk quintiles. For quintiles
1 through 5, odds ratios were 0.72, 0.52, 0.64, 0.66, and 0.71, respectively"
-
The
Rationale for Inhibiting 5alpha-Reductase Isoenzymes in the Prevention and
Treatment of Prostate Cancer - J Urol. 2008 Feb 14 -
"The 2 5alpha-reductase inhibitors currently
clinically available are finasteride, a type 2 5alpha-reductase inhibitor,
and dutasteride, a dual 5alpha-reductase inhibitor. Dual inhibition by
dutasteride has been shown to translate into a greater degree and
consistency of dihydrotestosterone suppression compared with finasteride.
The Prostate Cancer Prevention Trial showed that finasteride significantly
decreased the 7-year risk of prostate cancer in men with prostate specific
antigen 3.0 ng/ml or less, while the ongoing Reduction by Dutasteride of
Prostate Cancer Events study is assessing whether dutasteride decreases the
risk of biopsy detectable prostate cancer in men with prostate specific
antigen 2.5 to 10 ng/ml and a previous negative biopsy"
-
The importance of dual 5alpha-reductase inhibition in the treatment of male
pattern hair loss: results of a randomized placebo-controlled study of
dutasteride versus finasteride - J Am Acad Dermatol. 2006
Dec;55(6):1014-23 - "Dutasteride
increased target area hair count versus placebo in a dose-dependent fashion
and dutasteride 2.5 mg was superior to finasteride at 12 and 24 weeks"
- Note: Dutasteride is Avodart®.
See dutasteride at OffshoreRX.com
.
-
Should finasteride be used to prevent prostate cancer? - Curr Treat
Options Oncol. 2006 Sep;7(5):346-54 - "At trial's end, there was a 25%
reduction in period prevalence in all prostate cancers (24.4% for placebo vs
18.4% for finasteride)"
-
Finasteride-induced depression : A prospective study - BMC Clin
Pharmacol. 2006 Oct 7;6(1):7 - "finasteride might induce depressive symptoms; therefore this medication
should be prescribed cautiously for patients with high risk of depression"
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